Pulmonary hypertension associated with COPD

References

• AbrahamASColeRBBishopJMReversal of pulmonary hypertension by prolonged oxygen administration to patients with chronic bronchitisCirc Res196823147575661934
   PubMed Web of Science ®Google Scholar
• AgostoniPDoriaEGalliCNifedipine reduces pulmonary pressure and vascular tone during short- but not long-term treatment of pulmonary hypertension in patients with chronic obstructive pulmonary diseaseAm Rev Respir Dis198913912052912331
   PubMed Web of Science ®Google Scholar
• Alhenc-GelasFTsai CallahanKSStimulation of prostaglandin formation by vasoactive mediators in cultured human endothelial cellsProstaglandins198224723426819604
   PubMed Web of Science ®Google Scholar
• AlpSSkryganMSchmidtWESildenafil improves hemodynamic parameters in COPD – an investigation of six patientsPulm Pharmacol Ther2006193869016291503
   PubMed Web of Science ®Google Scholar
• AnthonisenNRConnettJEKileyJPThe effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline in FEV1: the Lung Health StudyJAMA199427214975057966841
   PubMed Web of Science ®Google Scholar
• AnthonisenNRConnettJEMurrayRPSmoking and lung function of Lung Health Study participants after 11 yearsAm J Respir Crit Care Med2002166675912204864
   PubMed Web of Science ®Google Scholar
• AnthonisenNRWrightECHodgkinJEIPPD Trial Group. Prognosis in chronic obstructive pulmonary diseaseAm Rev Respir Dis198613314203510578
   PubMed Web of Science ®Google Scholar
• ArcasoySMChristieJDFerrariVAEchocardiographic assessment of pulmonary hypertension in patients with advanced lung diseaseAm J Respir Crit Care Med20031677354012480614
   PubMed Web of Science ®Google Scholar
• BachDSCurtisJLChristensenPJPreoperative echocardiographic evaluation of patients referred for lung volume reduction surgeryChest1998114972809792564
   PubMed Web of Science ®Google Scholar
• BarberaJAPeinadoVISantosSReduced expression of endothelial nitric oxide synthase in pulmonary arteries of smokersAm J Respir Crit Care Med20011647091311520741
   PubMed Web of Science ®Google Scholar
• BarberaJAPeinadoVISantosSPulmonary hypertension in chronic obstructive pulmonary diseaseEur Respir J20032189290512765440
   PubMed Web of Science ®Google Scholar
• BarberaJARiverolaARocaJPulmonary vascular abnormalities and ventilation-perfusion relationships in mild chronic obstructive pulmonary diseaseAm J Respir Crit Care Med199414942398306040
   PubMed Web of Science ®Google Scholar
• BarberaJARogerNRocaJWorsening of pulmonary gas exchange with nitric oxide inhalation in chronic obstructive pulmonary diseaseLancet1996347436408618485
   PubMed Web of Science ®Google Scholar
• Ben-DorIMordechaiMRaccahACheocardiography versus right-sided heart catheterization among lung transplantation candidatesAnn Thorac Surg20068110566016488722
   PubMed Web of Science ®Google Scholar
• BonettiPOLermanLONapoliCStatin effects beyond lipid lowering: are they clinically relevant?Eur Heart J2003242254812590901
   PubMed Web of Science ®Google Scholar
• BoscoeMJGoodwinATAmraniMEndothelins and the lungInt J Biochem Cell Biol200032416210661893
   PubMed Web of Science ®Google Scholar
• BredikisAJLiebsonPRThe echocardiograpm in COPD: estimating right heart pressuresJ Respir Dis1998191918
   Google Scholar
• BurrowsBEarleRHCourse and prognosis of chronic obstructive lung disease: a prospective study of 200 patientsN Engl J Med19692803974045763088
   PubMed Web of Science ®Google Scholar
• BurrowsBKettelLJNidenAHPatterns of cardiovascular dysfunction in chronic obstructive lung diseaseN Engl J Med1972286912185013974
   PubMed Web of Science ®Google Scholar
• BurrowsBArterial oxygenation and pulmonary hemodynamics in patients with chronic airways obstructionAm Rev Respir Dis197411064704613234
   PubMed Web of Science ®Google Scholar
• CalverleyPMAHowatsonRFlenleyDCClinicopathological correlations in cor pulmonaleThorax19924749481412090
   PubMed Web of Science ®Google Scholar
• CarmelietPDorYHerbertJMRole of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesisNature1998394485909697772
   PubMed Web of Science ®Google Scholar
• CelliBRMacNeeWcommittee membersStandards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paperEur Respir J2004239324615219010
   PubMed Web of Science ®Google Scholar
• CerdaEEstebanAde la CalMAHemodynamic effects of vasodilators on pulmonary hypertension in decompensated chronic obstructive pulmonary diseaseCrit Care Med19851322133979067
   PubMed Web of Science ®Google Scholar
• ChaouatABugnetASKadaouiNSevere pulmonary hypertension and chronic obstructive pulmonary diseaseAm J Respir Crit Care Med20051721899415831842
   PubMed Web of Science ®Google Scholar
• ChenSJChenYFMengQCEndothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in ratsJ Appl Physiol1995792122318847282
   PubMed Web of Science ®Google Scholar
• ChettyKGBrownSELightRWIdentification of pulmonary hypertension in chronic obstructive pulmonary disease form routine chest radiographsAm Rev Respir Dis1982126338417103259
   PubMed Web of Science ®Google Scholar
• ChhabraSKDeSClinical significance of hilar thoracic index and width of right descending branch of pulmonary artery in chronic obstructive pulmonary diseaseChest200446917
   Google Scholar
• ChristensenCCRygMSEdvardsenARelationship between exercise desaturation and pulmonary haemodynamics in COPD patientsEur Respir J200424580615459136
   PubMed Web of Science ®Google Scholar
• CliniECremonaGCampanaMProduction of endogenous nitric oxide in chronic obstructive pulmonary disease and patients with cor pulmonale. Correlates with echo-Doppler assessmentAm J Respir Crit Care Med20001624465010934068
   PubMed Web of Science ®Google Scholar
• CottinVNunesHBrilletPYCombined pulmonary fibrosis and emphysema: a distinct underrecognised entityEur Respir J20052658659316204587
   PubMed Web of Science ®Google Scholar
• Dal NogareARRubinLJThe effects of hydralazine on exercise capacity in pulmonary hypertension secondary to chronic obstructive pulmonary diseaseAm Rev Respir Dis198613338593954247
   PubMed Web of Science ®Google Scholar
• DefouilloyCTeigerESediameSPolycythemia impairs vasodilator response to acetylcholine in patients with chronic hypoxemic lung diseaseAm J Respir Crit Care Med19981571452609603123
   PubMed Web of Science ®Google Scholar
• DiasCAAssadRSCaneoLFReversible pulmonary trunk banding. II. An experimental model for rapid pulmonary ventricular hypertrophyJ Thorac Cardiovasc Surg2002124999100612407385
   PubMed Web of Science ®Google Scholar
• DiCarloVSChenSJMengQCETA-receptor antagonist prevents and reverses chronic hypoxia-induced pulmonary hypertension in ratAm J Physiol1995269L69077491990
   PubMed Web of Science ®Google Scholar
• Dinh-XuanATHigenbottamTWClellandCAImpairment of endothelium-dependent pulmonary-artery relaxation in chronic obstructive lung diseaseN Engl J Med19913241539472027358
   PubMed Web of Science ®Google Scholar
• DoiMNakanoKHiramotoTSignificance of pulmonary artery pressure in emphysema patients with mild-to-moderate hypoxemiaRespiratory Medicine2003979152012924518
   PubMed Web of Science ®Google Scholar
• DubinDPrattREKookeJPEndothelin, a potent vasoconstrictor, is a vascular smooth muscle mitogenJ Vasc Biol Med198911504
   Google Scholar
• EddahibiSChaouatAMorrellNPolymorphism of the serotonin transporter gene and pulmonary hypertension in chronic obstructive pulmonary diseaseCirculation200310818394414530202
   PubMed Web of Science ®Google Scholar
• EddahibiSChaouatATuLInterleukin-6 gene polymorphism confers susceptibility to pulmonary hypertension in chronic obstructive pulmonary diseaseProc Am Thorac Soc20063475616921112
   PubMedGoogle Scholar
• EddahibiSHumbertMFadelESerotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertensionJ Clin Invest200110811415011602621
   PubMed Web of Science ®Google Scholar
• EltonTSOparilSTaylorGRNormobaric hypoxia stimulates endothelin-1 gene expression in the ratAm J Physiol1992263R126041481936
   PubMed Web of Science ®Google Scholar
• FishmanAPState of the art: chronic cor pulmonaleAm Rev Respir Dis197611477594788575
   PubMed Web of Science ®Google Scholar
• FletcherECLuckettRAGoodnight-WhiteSA double-blind trial of nocturnal supplemental oxygen for sleep desaturation in patients with chronic obstructive pulmonary disease and a daytime PaO2 above 60 mm HgAm Rev Respir Dis1992145107061586049
   PubMed Web of Science ®Google Scholar
• FujimotoKMatsuzawaYYamaguchiSBenefits of oxygen on exercise performance and pulmonary hemodynamics in patients with COPD with mild hypoxemiaChest20021224576312171817
   PubMed Web of Science ®Google Scholar
• GarzanitiNel AllafDD’OrioVHemodynamic effects of nifedipine on secondary pulmonary hypertension in manActa Cardiol198540207153873156
   PubMed Web of Science ®Google Scholar
• GerberJGVoelkelNFNiesNModeration of hypoxic vasoconstriction by infused arachidonic acid: role of PGI2J Appl Physiol198049107126995413
   PubMed Web of Science ®Google Scholar
• GiaidASalehDReduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertensionN Engl J Med1995333214217540722
   PubMed Web of Science ®Google Scholar
• GiaidAYanagisawaMLanglebenDExpression of endothelin-1 in the lungs of patients with pulmonary hypertensionN Engl J Med1993328173298497283
   PubMed Web of Science ®Google Scholar
• GroverRFVogelJHVoigtGCReversal of high altitude pulmonary hypertensionAm J Cardiol196618928325924007
   PubMed Web of Science ®Google Scholar
• HaimoviciJBATrotman-DickensonBHalpernEFRelationship between pulmonary artery diameter at computed tomography and pulmonary artery pressures at right-sided heart catheterizationAcad Radiol199743279156228
   PubMed Web of Science ®Google Scholar
• HaleKAEwingSLGosnellBALung disease in long-term cigarette smokers with and without chronic air-flow obstructionAm Rev Respir Dis1984130716216497154
   PubMed Web of Science ®Google Scholar
• HaleKANiewoehnerDECosioMGMorphologic changes in the muscular pulmonary arteries: relationship to cigarette smoking, airway disease, and emphysemaAm Rev Respir Dis198012227387416604
   PubMed Web of Science ®Google Scholar
• HaniudaMKuboKFujimotoKEffects of pulmonary artery remodeling on pulmonary circulation after lung volume reduction surgeryThorac Cardiovasc Surg200351154812833205
   PubMed Web of Science ®Google Scholar
• HanninkMDonoghueDJStructure and function of platelet-derived growth factor (PDGF) and related proteinsBiochim Biophys Acta19891981102546599
   PubMed Web of Science ®Google Scholar
• HaraSMorishitaRToneYOverexpression of prostacyclin synthase inhibits growth of vascular smooth muscle cellsBiochem Biophys Res Commun199521686277488205
   PubMed Web of Science ®Google Scholar
• HarriganHAJonesKABC of clinical electrocardiography: conditions affecting the right side of the heartBMJ20023241201412016190
   PubMed Web of Science ®Google Scholar
• HeathDEdwardsCWinsonMEffects on the right ventricle, pulmonary vasculature, and carotid bodies of the rat of exposure to, and recovery from, simulated high altitudeThorax1973282484685208
   PubMed Web of Science ®Google Scholar
• HickenPHeathDBrewerDBThe small pulmonary arteries in emphysemaJ Pathol Bacteriol196590107145843931
   PubMedGoogle Scholar
• HidaWTunYKikuchiYPulmonary hypertension in patients with chronic obstructive pulmonary disease: recent advances in pathophysiology and managementRespirology2002731311896895
   PubMed Web of Science ®Google Scholar
• HighamMADawsonDJoshiJUtility of echocardiography in assessment of pulmonary hypertension secondary to COPDEur Respir J200117350511405510
   PubMed Web of Science ®Google Scholar
• HimelmanRBStruveSNBrownJKImproved recognition of cor pulmonale in patients with severe chronic obstructive pulmonary diseaseAmer J Med19888489183364448
   PubMed Web of Science ®Google Scholar
• HuJDischerDJBishopricNHHypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strandBiochem Biophys Res Commun199824589499588211
   PubMed Web of Science ®Google Scholar
• HurdSThe impact of COPD on lung health worldwide: epidemiology and incidenceChest2000117S14
   Web of Science ®Google Scholar
• IyerNVKotchLEAganiFCellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alphaGenes Dev199812149629436976
   PubMed Web of Science ®Google Scholar
• JoppaPPetrasovaDStancakBSystemic inflammation in patients with COPD and pulmonary hypertensionChest20061303263316899829
   PubMed Web of Science ®Google Scholar
• KanazawaHOkamotoTHirataKDeletion polymorphisms in the angiotensin converting enzyme gene are associated with pulmonary hypertension evoked by exercise challenge in patients with chronic obstructive pulmonary diseaseAm J Respir Crit Care Med20001621235811029323
   PubMed Web of Science ®Google Scholar
• KellerCAShepardJWJrChunDSEffects of hydralazine on hemodynamics, ventilation, and gas exchange in patients with chronic obstructive pulmonary disease and pulmonary hypertensionAm Rev Respir Dis1984130606116486560
   PubMed Web of Science ®Google Scholar
• KesslerRFallerMFourgautGPredictive factors of hospitalization for acute exacerbation in a series of 64 patients with chronic obstructive pulmonary diseaseAm J Respir Crit Care Med1999159158649872834
   PubMed Web of Science ®Google Scholar
• KesslerRFallerMWeitzenblumE“Natural history” of pulmonary hypertension in a series of 131 patients with chronic obstructive lung diseaseAm J Respir Crit Care Med20011642192411463591
   PubMed Web of Science ®Google Scholar
• KuboKGeRLKoizumiTFujimotoKPulmonary artery remodeling modifies pulmonary hypertension during exercise in severe emphysemaRespir Physiol200012071910786646
   PubMedGoogle Scholar
• LaabanJPDieboldBZelinskiRNoninvasive estimation of systolic pulmonary artery pressure using Doppler echocardiography in patients with chronic obstructive pulmonary diseaseChest1989961258622582830
   PubMed Web of Science ®Google Scholar
• LaDouceurDMFlynnMAKeiserJAETA and ETB receptors coexist on rabbit pulmonary artery vascular smooth muscle mediating contractionBiochem Biophys Res Commun1993196209158216294
   PubMed Web of Science ®Google Scholar
• LeeJDTaraseviciene-StewartLKeithRThe expression of prostacyclin synthase is decreased in the small pulmonary arteries from patients with emphysemaChest2005128575S16373836
   PubMed Web of Science ®Google Scholar
• LeeJHLeeDSKimEKSimvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungsAm J Respir Crit Care Med20051729879316002570
   PubMed Web of Science ®Google Scholar
• LejeunePMolsPNaeijeRAcute hemodynamic effects of controlled oxygen therapy in decompensated chronic obstructive pulmonary diseaseCrit Care Med198412103256510000
   PubMed Web of Science ®Google Scholar
• LeopoldJGGoughJThe centrilobular form of hypertrophic emphysema and its relation to chronic bronchitisThorax1957122193513467881
   PubMedGoogle Scholar
• LiuSChenWLuoYRelationship among dosages of aminophylline, plasma levels of theophylline and variation of pulmonary arterial pressureHua Xi Yi Ke Da Xue Xue Bao19922387901398633
   PubMedGoogle Scholar
• LouieEKLinSSReynertsonSIPressure and volume loading of the right ventricle have opposite effects on the left ventricle ejection fractionCirculation199592819247641362
   PubMed Web of Science ®Google Scholar
• MageeFWrightJLWiggsBRPulmonary vascular structure and function in chronic obstructive pulmonary diseaseThorax19884318393406902
   PubMed Web of Science ®Google Scholar
• MatsuyamaWOhkuboRMichizonoKUsefulness of transcutaneous Doppler jugular venous echo to predict pulmonary hypertension in COPD patientsEur Respir J20011711283111491154
   PubMed Web of Science ®Google Scholar
• MatthayRASchwarzMIEllisJHJrPulmonary artery hypertension in chronic obstructive pulmonary disease: determination by chest radiographyInvest Radiol198116951007216709
   PubMed Web of Science ®Google Scholar
• MechtcheriakovaDWlachosAHolzmullerHVascular endothelial cell growth factor-induced tissue factor expression in endothelial cells is mediated by EGR-1Blood19999338112310339488
   PubMed Web of Science ®Google Scholar
• Medical Research Council Working PartyLong term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema. Report of the Medical Research Council Working PartyLancet1981168166110912
   PubMed Web of Science ®Google Scholar
• MelotCHallemansRNaeijeRDeleterious effect of nifedipine on pulmonary gas exchange in chronic obstructive pulmonary diseaseAm Rev Respir Dis1984130612166091508
   PubMed Web of Science ®Google Scholar
• MillardJReidJRight ventricular hypertrophy and its relationship to chronic bronchitis and emphysemaBrit J Dis Chest197468103104277638
   PubMedGoogle Scholar
• MorrellNWHighamMAPhillipsPGPilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary diseaseRespir Res2005611015631627
   PubMed Web of Science ®Google Scholar
• MorrellNWMorrisKGStenmarkKRRole of angiotensin-converting enzyme and angiotensin II in development of hypoxic pulmonary hypertensionAm J Physiol1995269H1186947485548
   PubMedGoogle Scholar
• MuradFWhat are the molecular mechanisms for the antiproliferative effects of nitric oxide and cGMP in vascular smooth muscle?Circulation199795110139054833
   PubMed Web of Science ®Google Scholar
• MuramotoACaldwellJAlbertRKNifedipine dilates the pulmonary vasculature without producing symptomatic systemic hypotension in upright resting and exercising patients with pulmonary hypertension secondary to chronic obstructive pulmonary diseaseAm Rev Respir Dis198513296364062050
   PubMed Web of Science ®Google Scholar
• MurrayCJLopezADAlternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease StudyLancet199734914985049167458
   PubMed Web of Science ®Google Scholar
• NaeijeRPulmonary hypertension and right heart failure in chronic obstructive pulmonary diseaseProc Am Thorac Soc2005220216113464
   PubMedGoogle Scholar
• NakamuraAKasamatsuNHashizumeIEffects of hemoglobin on pulmonary arterial pressure and pulmonary vascular resistance in patients with chronic emphysemaRespiration200067502611070452
   PubMed Web of Science ®Google Scholar
• Nana-SinkamSPLeeJDStearmanRProstacyclin synthase in smoking-related lung diseaseProc Am Thorac Soc2006351716921134
   PubMedGoogle Scholar
• NgCSWellsAUPadleySPA CT sign of chronic pulmonary arterial hypertension: the ratio of main pulmonary artery to aortic diameterJ Thoracic Imaging1999142708
   PubMed Web of Science ®Google Scholar
• Nocturnal Oxygen Therapy Trial GroupContinuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: a clinical trialAnn Intern Med19809339186776858
   PubMed Web of Science ®Google Scholar
• NongZStassenJMMoonsLInhibition of tissue angiotensin-converting enzyme with quinapril reduces hypoxic pulmonary hypertension and pulmonary vascular remodelingCirculation199694194178873672
   PubMed Web of Science ®Google Scholar
• OlveySKRedutoLAStevensPMFirst pass radionuclide assessment of right and left ventricular ejection fraction in chronic pulmonary disease. Effect of oxygen upon exercise responseChest198078497471843
   PubMed Web of Science ®Google Scholar
• Oswald-MammosserMApprillMBachezPPulmonary hemodynamics in chronic obstructive pulmonary disease of the emphysematous typeRespiration199158304101792422
   PubMed Web of Science ®Google Scholar
• Oswald-MammosserMOswaldTNyankiyeENon-invasive diagnosis of pulmonary hypertension in chronic obstructive pulmonary disease. Comparison of ECG, radiological measurements, echocardiography and myocardial scintigraphyEur J Respir Dis198771419293443164
   PubMedGoogle Scholar
• PapaioannouAIKostikasKKolliaPClinical implications for vascular endothelial growth factor in the lung: friend or foe?Respir Res2006712817044926
   PubMed Web of Science ®Google Scholar
• PatakasDGeorgopoulosDRodiniHEffects of captopril in patients with chronic obstructive pulmonary disease and secondary pulmonary hypertensionPostgrad Med J19886419353050941
   PubMed Web of Science ®Google Scholar
• PeaseRDBenumofJLTrousdaleFRPAO2 and PVO2 interaction on hypoxic pulmonary vasoconstrictionJ Appl Physiol19825313497118626
   PubMed Web of Science ®Google Scholar
• PeinadoVIBarberaJAAbatePInflammatory reaction in pulmonary muscular arteries of patients with mild chronic obstructive pulmonary diseaseAm J Respir Crit Care Med199915916051110228134
   PubMed Web of Science ®Google Scholar
• PeinadoVIBarberaJARamirezJEndothelial dysfunction in pulmonary arteries of patients with mild COPDAm J Physiol1998274L908139609729
   PubMed Web of Science ®Google Scholar
• Pepke-ZabaJHigenbottamTWDinh-XuanATInhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertensionLancet1991338117341682593
   PubMed Web of Science ®Google Scholar
• PilatesNDJacobsLERerkpattanapipatPClinical predictors of pulmonary hypertension in patients undergoing liver transplant evaluationLiver Transpl20006859110648583
   PubMed Web of Science ®Google Scholar
• RabeKFTenorHDentGIdentification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitorsAm J Physiol199426653643
   PubMed Web of Science ®Google Scholar
• RaesideDABrownAPatelKRAmbulatory pulmonary artery pressure monitoring during sleep and exercise in normal individuals and patients with COPDThorax2002571050312454300
   PubMed Web of Science ®Google Scholar
• ReevesJTGroverRFInsights by Peruvian scientists into the pathogenesis of human chronic hypoxic pulmonary hypertensionJ Appl Physiol200598384915591308
   PubMed Web of Science ®Google Scholar
• RigatBHubertCAlhenc-GelasFAn insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levelsJ Clin Invest199086134361976655
   PubMed Web of Science ®Google Scholar
• RigatBHubertCCorvolPPCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxy peptidase 1)Nucl Acids Res19922014331313972
   PubMed Web of Science ®Google Scholar
• RolandMBhowmikASapsfordRJSputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary diseaseThorax20015630511120901
   PubMed Web of Science ®Google Scholar
• SalvaterraCGRubinLJInvestigation and management of pulmonary hypertension in chronic obstructive pulmonary diseaseAm Rev Respir Dis19931481414178239185
   PubMed Web of Science ®Google Scholar
• SantosSPeinadoVIRamirezJEnhanced expression of vascular endothelial growth factor in pulmonary arteries of smokers and patients with moderate chronic obstructive pulmonary diseaseAm J Respir Crit Care Med20031671250612615615
   PubMed Web of Science ®Google Scholar
• SantosSPeinadoVIRamirezCharacterization of pulmonary vascular remodeling in smokers and patients with mild COPDEur Respir J200219632811998991
   PubMed Web of Science ®Google Scholar
• ScharfSMIqbalMKellerCNational Emphysema Treatment Trial (NETT) Group. Hemodynamic characterization of patients with severe emphysemaAm J Respir Crit Care Med20021663142212153963
   PubMed Web of Science ®Google Scholar
• SchermulyRTDonyEGhofraniHAReversal of experimental pulmonary hypertension by PDGF inhibitionJ Clin Invest200511528112116200212
   PubMed Web of Science ®Google Scholar
• ScottKWMA clinicopathological study of fatal chronic airways obstructionThorax197631693701138210
   PubMed Web of Science ®Google Scholar
• SemenzaGLHIF-1: mediator of physiological and pathophysiological responses to hypoxiaJ Appl Physiol20008814748010749844
   PubMed Web of Science ®Google Scholar
• SemenzaGLOxygen-regulated transcription factors and their role in pulmonary diseaseRespiratory Research200011596211667980
   PubMedGoogle Scholar
• SherrillDLEnrightPClineMRates of decline in lung function among subjects who restart cigarette smokingChest1996109100158635322
   PubMed Web of Science ®Google Scholar
• SpiropoulosKTrakadaGNikolaouEEndothelin-1 levels in the pathophysiology of chronic obstructive pulmonary disease and bronchial asthmaRespir Med200397983912924528
   PubMed Web of Science ®Google Scholar
• StevensSMSharmaKSzidonPSevere pulmonary hypertension associated with COPDAnn Transplant2000581211147031
   PubMedGoogle Scholar
• SturaniCBasseinLSchiavinaMOral nifedipine in chronic cor pulmonale secondary to severe chronic obstructive pulmonary disease (COPD)Chest198384135426872591
   PubMed Web of Science ®Google Scholar
• SuYHanWGiraldoCEffect of cigarette smoke extract on nitric oxide synthase in pulmonary artery endothelial cellsAm J Respir Cell Mol Biol199819819259806747
   PubMed Web of Science ®Google Scholar
• TanRTKuzoRGoodmanLRLUtility of CT scan evaluation for predicting pulmonary hypertension in patients with parenchymal lung diseaseChest199811312509596302
   PubMed Web of Science ®Google Scholar
• Taraseviciene-StewartLKasaharaYAlgerLInhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertensionFASEB J2001154273811156958
   PubMed Web of Science ®Google Scholar
• ThabutGDauriatGSternJBPulmonary hemodynamics in advanced COPD candidates for lung volume reduction surgery or lung transplantationChest20051271531615888824
   PubMed Web of Science ®Google Scholar
• ThompsonBTHassounPMKradinRLAcute and chronic hypoxic pulmonary hypertension in guinea pigsJ Appl Physiol19896692082708221
   PubMed Web of Science ®Google Scholar
• Tillie-LeblondIMarquetteCHPerezTPulmonary embolism in patients with unexplained exacerbation of chronic obstructive pulmonary disease: prevalence and risk factorsAnn Intern Med2006144390616549851
   PubMed Web of Science ®Google Scholar
• TimmsRMKhajaFUWilliamsGWHemodynamic response to oxygen therapy in chronic obstructive pulmonary diseaseAnn Intern Med198510229363966742
   PubMed Web of Science ®Google Scholar
• TkacovaRJoppaPStancakBThe link between angiotensin-converting enzyme genotype and pulmonary artery pressure in patients with COPDWien Klin Wochenschr2005117210415875760
   PubMed Web of Science ®Google Scholar
• TramarinRTorbickiAMarchandiseBDoppler echocardiographic evaluation of pulmonary artery pressure in chronic obstructive pulmonary disease. A European multicentre study. Working Group on Noninvasive Evaluation of Pulmonary Artery Pressure. European Office of the World Health Organization, CopenhagenEur Heart J199112103112044542
   PubMed Web of Science ®Google Scholar
• TuderRMCoolCDGeraciMWProstacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertensionAm J Respir Crit Care Med199915919253210351941
   PubMed Web of Science ®Google Scholar
• van DijkAPTorbickiAMore on the noninvasive diagnosis of pulmonary hypertension: Doppler echocardiography revisitedEur Respir J19958144598575567
   PubMed Web of Science ®Google Scholar
• VenderRLChronic hypoxic pulmonary hypertension. Cell biology to pathophysiologyChest1994106236438020277
   PubMed Web of Science ®Google Scholar
• VoelkelNFQuaifeRALeinwandLARight ventricular function and failure: report of a national heart, lung, and blood institute working group on cellular and molecular mechanisms of right heart failureCirculation200611418839117060398
   PubMed Web of Science ®Google Scholar
• Von EulerULiljerstrandGObservations on the pulmonary arterial blood pressure in the catAct Physiol Scand19461230120
   Google Scholar
• VonbankKZiescheRHigenbottamTWControlled prospective randomized trial on the effects on pulmonary haemodynamics of the ambulatory long term use of nitric oxide and oxygen in patients with severe COPDThorax2003582899312668787
   PubMed Web of Science ®Google Scholar
• Vonk-NoordegraafAMarcusJTHolverdaSEarly changes of cardiac structure and function in COPD patients with mild hypoxemiaChest2005127189890315947300
   PubMed Web of Science ®Google Scholar
• WedgwoodSDettmanRWBlackSMET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen speciesAm J Physiol Lung Cell Mol Physiol2001281L10586711597896
   PubMed Web of Science ®Google Scholar
• WeirEKArcherSLThe mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channelsFASEB J1995918397781921
   PubMed Web of Science ®Google Scholar
• WeitzenblumEHirthCDucoloneAPrognostic value of pulmonary artery pressure in chronic obstructive pulmonary diseaseThorax19813675287330793
   PubMed Web of Science ®Google Scholar
• WeitzenblumESautegeauAEhrhartMLong-term oxygen therapy can reverse the progression of pulmonary hypertension in patients with chronic obstructive pulmonary diseaseAm Rev Respir Dis198513149383922267
   PubMed Web of Science ®Google Scholar
• WeitzenblumESautegeauAErhartMLong-term course of pulmonary arterial pressure in chronic obstructive pulmonary diseaseAm Rev Respir Dis198413099386439091
   PubMed Web of Science ®Google Scholar
• WilkinsonMLanghorneCAHeathDA pathophysiological study of 10 cases of hypoxic cor pulmonaleQ J Med19886665853174923
   PubMedGoogle Scholar
• WrightJLLawsonLParePDThe structure and function of the pulmonary vasculature in mild chronic obstructive pulmonary disease. The effect of oxygen and exerciseAm Rev Respir Dis198312870276625346
   PubMed Web of Science ®Google Scholar
• WrightJLPettyTThurlbeckWMAnalysis of the structure of the muscular pulmonary arteries in patients with pulmonary hypertension and COPD: National Institutes of Health nocturnal oxygen therapy trialLung1992170109241501507
   PubMed Web of Science ®Google Scholar
• WrightJLTaiHChurgACigarette smoke induces persisting increases of vasoactive mediators in pulmonary arteriesAm J Respir Cell Mol Biol200431501915242846
   PubMed Web of Science ®Google Scholar
• WrightJLTaiHDaiJCigarette smoke induces rapid changes in gene expression in pulmonary arteriesLab Invest2002821391812379773
   PubMed Web of Science ®Google Scholar
• WrightJLRelationship of pulmonary arterial pressure and airflow obstruction to emphysemaJ Appl Physiol199374132048482673
   PubMed Web of Science ®Google Scholar
• YanSFZouYSGaoYTissue factor transcription driven by EGR-1 is a critical mechanism of murine pulmonary fibrin deposition in hypoxiaProc Natl Acad Sci USA19989582983039653181
   PubMed Web of Science ®Google Scholar
• YildizPOflazHCineNGene polymorphisms of endothelial nitric oxide synthase enzyme associated with pulmonary hypertension in patients with COPDRespir Med2003971282814682408
   PubMed Web of Science ®Google Scholar
• YuAYFridMGShimodaLATemporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor 1 in the lungAm J Physiol1998275L818269755115
   PubMed Web of Science ®Google Scholar