Markers of early disease and prognosis in COPD

References

• PauwelsRABuistASCalverleyPMJenkinsCRHurdSSGlobal strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summaryAm J Respir Crit Care Med20011631256127611316667
   PubMedGoogle Scholar
• MathersCDLoncarDProjections of global mortality and burden of disease from 2002 to 2030PLoS Med20063e44217132052
   PubMed Web of Science ®Google Scholar
• DahlMBauerAKArredouaniMProtection against inhaled oxidants through scavenging of oxidized lipids by macrophage receptors MARCO and SR-AI/IIJ Clin Invest200711775776417332894
   PubMed Web of Science ®Google Scholar
• OwenCARoles for proteinases in the pathogenesis of chronic obstructive pulmonary diseaseInt J Chron Obstruct Pulmon Dis2008325326818686734
   PubMedGoogle Scholar
• Taraseviciene-StewartLVoelkelNFMolecular pathogenesis of emphysemaJ Clin Invest200811839440218246188
   PubMed Web of Science ®Google Scholar
• YoshidaTTuderRMPathobiology of cigarette smoke-induced chronic obstructive pulmonary diseasePhysiol Rev2007871047108217615396
   PubMed Web of Science ®Google Scholar
• CazzolaMMacNeeWMartinezFJOutcomes for COPD pharmacological trials: from lung function to biomarkersEur Respir J20083141646918238951
   PubMed Web of Science ®Google Scholar
• JonesPWAgustiAGOutcomes and markers in the assessment of chronic obstructive pulmonary diseaseEur Respir J20062782283216585091
   PubMed Web of Science ®Google Scholar
• VestboJAndersonWCoxsonHOEvaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE)Eur Respir J20083186987318216052
   PubMed Web of Science ®Google Scholar
• Epidemiology of chest pain and angina pectoris, with special reference to treatment needsActa Med Scand Suppl198468211206587759
   PubMedGoogle Scholar
• The Copenhagen City Heart StudyOsterbroundersogelsen. A book of tables with data from the first examination (1976–78) and a five year follow-up (1981–83). The Copenhagen City Heart Study GroupScand J Soc Med Suppl19894111602711133
   PubMedGoogle Scholar
• SchnohrPJensenGLangePScharlingHAppleyardMThe Copenhagen City Heart Study – Østerbrounders⊘gelsen. Tables with data from the third examination 1991–1994Eur Heart J Suppl20013H1H83
   Web of Science ®Google Scholar
• Garcia-LaordenMISole-ViolanJRodriguezDCMannose-binding lectin and mannose-binding lectin-associated serine protease 2 in susceptibility, severity, and outcome of pneumonia in adultsJ Allergy Clin Immunol20081223687437418582923
   PubMed Web of Science ®Google Scholar
• YangIASeeneySLWolterJMMannose-binding lectin gene polymorphism predicts hospital admissions for COPD infectionsGenes Immun2003426927412761563
   PubMed Web of Science ®Google Scholar
• GanWQManSFSenthilselvanASinDDAssociation between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysisThorax20045957458015223864
   PubMed Web of Science ®Google Scholar
• OlafsdottirISGislasonTThjodleifssonBGender differences in the association between C-reactive protein, lung function impairment, and COPDInt J Chron Obstruct Pulmon Dis2007263564218268938
   PubMedGoogle Scholar
• GooptuBLomasDAPolymers and inflammation: disease mechanisms of the serpinopathiesJ Exp Med20082051529153418591408
   PubMed Web of Science ®Google Scholar
• DahlMTybjaerg-HansenALangePVestboJNordestgaardBGChange in lung function and morbidity from chronic obstructive pulmonary disease in alpha1-antitrypsin MZ heterozygotes: A longitudinal study of the general populationAnn Intern Med200213627027911848724
   PubMed Web of Science ®Google Scholar
• DahlMNordestgaardBGLangePVestboJTybjaerg-HansenAMolecular diagnosis of intermediate and severe alpha(1)-antitrypsin deficiency: MZ individuals with chronic obstructive pulmonary disease may have lower lung function than MM individualsClin Chem200147566211148177
   PubMed Web of Science ®Google Scholar
• DahlMHershCPLyNPBerkeyCSSilvermanEKNordestgaardBGThe protease inhibitor PI*S allele and COPD: a meta-analysisEur Respir J200526677615994391
   PubMed Web of Science ®Google Scholar
• HershCPDahlMLyNPBerkeyCSNordestgaardBGSilvermanEKChronic obstructive pulmonary disease in alpha1-antitrypsin PI MZ heterozygotes: a meta-analysisThorax20045984384915454649
   PubMed Web of Science ®Google Scholar
• DahlMNordestgaardBGTybjærg-HansenABrunsDELoYMDWittwerCTMolecular diagnosis of intermediate and severe alpha1-antitrypsin deficiency by use of multiplex polymerase chain reactionMolecular testing in laboratory medicineWashington DCAACC Press2002250258
   Google Scholar
• DahlMTybjaerg-HansenALangePNordestgaardBGDeltaF508 heterozygosity in cystic fibrosis and susceptibility to asthmaLancet1998351191119139654257
   PubMed Web of Science ®Google Scholar
• DahlMNordestgaardBGLangePTybjaerg-HansenAFifteen-year follow-up of pulmonary function in individuals heterozygous for the cystic fibrosis phenylalanine-508 deletionJ Allergy Clin Immunol200110781882311344348
   PubMed Web of Science ®Google Scholar
• DahlMTybjaerg-HansenAWittrupHHLangePNordestgaardBGCystic fibrosis Delta F508 heterozygotes, smoking, and reproduction: studies of 9141 individuals from a general population sampleGenomics19985089969628826
   PubMed Web of Science ®Google Scholar
• EstivillXBancellsCRamosCGeographic distribution and regional origin of 272 cystic fibrosis mutations in European populations. The Biomed CF Mutation Analysis ConsortiumHum Mutat1997101351549259197
   PubMed Web of Science ®Google Scholar
• DahlMTybjaerg-HansenALangePNordestgaardBGAsthma and COPD in cystic fibrosis intron-8 5T carriers. A population-based studyRespir Res2005611316212675
   PubMed Web of Science ®Google Scholar
• DelaneySJRichDPThomsonSACystic fibrosis transmembrane conductance regulator splice variants are not conserved and fail to produce chloride channelsNat Genet199344264317691356
   PubMed Web of Science ®Google Scholar
• CastellaniCQuinziiCAltieriSMastellaGAssaelBMA pilot survey of cystic fibrosis clinical manifestations in CFTR mutation heterozygotesGenet Test2001524925411788092
   PubMedGoogle Scholar
• ConneallyPMMerrittADYuPLCystic fibrosis: population geneticsTex Rep Biol Med1973316396504595586
   PubMedGoogle Scholar
• de CidRChomelJCLazaroCCFTR and asthma in the French EGEA studyEur J Hum Genet20019676911175304
   PubMed Web of Science ®Google Scholar
• GriesenbachUGeddesDMAltonEWThe pathogenic consequences of a single mutated CFTR geneThorax199954Suppl 2S19S2310451687
   PubMed Web of Science ®Google Scholar
• HoffjanSNicolaeDOberCAssociation studies for asthma and atopic diseases: a comprehensive review of the literatureRespir Res200341414748924
   PubMed Web of Science ®Google Scholar
• LazaroCde CidRSunyerJMissense mutations in the cystic fibrosis gene in adult patients with asthmaHum Mutat19991451051910571949
   PubMed Web of Science ®Google Scholar
• LowenfelsABMaisonneuvePPalysBSchoniMHRedemannBDeltaF508 heterozygosity and asthmaLancet19983529859879752839
   PubMed Web of Science ®Google Scholar
• MennieMGilfillanABrockDJListonWAHeterozygotes for the delta F508 cystic fibrosis allele are not protected against bronchial asthmaNat Med199519789797489375
   PubMed Web of Science ®Google Scholar
• Munthe-KaasMCLodrup CarlsenKCCarlsenKHCFTR gene mutations and asthma in the Norwegian Environment and Childhood Asthma studyRespir Med20061002121212816678395
   PubMed Web of Science ®Google Scholar
• SchroederSAGaughanDMSwiftMProtection against bronchial asthma by CFTR delta F508 mutation: a heterozygote advantage in cystic fibrosisNat Med199517037057585155
   PubMed Web of Science ®Google Scholar
• TzetisMEfthymiadouAStrofalisSCFTR genemutations–including three novel nucleotide substitutions – and haplotype background in patients with asthma, disseminated bronchiectasis and chronic obstructive pulmonary diseaseHum Genet200110821622111354633
   PubMed Web of Science ®Google Scholar
• HolmskovUThielSJenseniusJCCollections and ficolins: humoral lectins of the innate immune defenseAnnu Rev Immunol20032154757812524383
   PubMed Web of Science ®Google Scholar
• TurnerMWThe role of mannose-binding lectin in health and diseaseMol Immunol20034042342914568388
   PubMed Web of Science ®Google Scholar
• EisenDPMinchintonRMImpact of mannose-binding lectin on susceptibility to infectious diseasesClin Infect Dis2003371496150514614673
   PubMed Web of Science ®Google Scholar
• NagyAKozmaGTKeszeiMTreszlAFalusASzalaiCThe development of asthma in children infected with Chlamydia pneumoniae is dependent on the modifying effect of mannose-binding lectinJ Allergy Clin Immunol200311272973414564351
   PubMed Web of Science ®Google Scholar
• DahlMTybjaerg-HansenASchnohrPNordestgaardBGA population-based study of morbidity and mortality in mannose-binding lectin deficiencyJ Exp Med20041991391139915148337
   PubMed Web of Science ®Google Scholar
• KochAMelbyeMSorensenPAcute respiratory tract infections and mannose-binding lectin insufficiency during early childhoodJAMA20012851316132111255386
   PubMed Web of Science ®Google Scholar
• DemeoDLMarianiTJLangeCThe SERPINE2 Gene Is Associated with Chronic Obstructive Pulmonary DiseaseAm J Hum Genet20067825326416358219
   PubMed Web of Science ®Google Scholar
• ZhuGWarrenLAponteJThe SERPINE2 gene is associated with chronic obstructive pulmonary disease in two large populationsAm J Respir Crit Care Med200717616717317446335
   PubMed Web of Science ®Google Scholar
• DahlMBowlerRPJuulKCrapoJDLevySNordestgaardBGSuperoxide dismutase 3 polymorphism associated with reduced lung function in two large populationsAm J Respir Crit Care Med200817890691218703790
   PubMed Web of Science ®Google Scholar
• DemeoDLHershCPHoffmanEAGenetic determinants of emphysema distribution in the national emphysema treatment trialAm J Respir Crit Care Med2007176424817363767
   PubMed Web of Science ®Google Scholar
• JuulKTybjaerg-HansenAMarklundSLangePNordestgaardBGGenetically increased antioxidative protection and decreased chronic obstructive pulmonary diseaseAm J Respir Crit Care Med200617385886416399992
   PubMed Web of Science ®Google Scholar
• SmithCAHarrisonDJAssociation between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysemaLancet19973506306339288046
   PubMed Web of Science ®Google Scholar
• SeifartCPlagensAGenetics of chronic obstructive pulmonary diseaseInt J Chron Obstruct Pulmon Dis2007254155018268927
   PubMedGoogle Scholar
• SilvermanEKProgress in chronic obstructive pulmonary disease geneticsProc Am Thorac Soc2006340540816799082
   PubMedGoogle Scholar
• DahlMTybjaerg-HansenAVestboJLangePNordestgaardBGElevated plasma fibrinogen associated with reduced pulmonary function and increased risk of chronic obstructive pulmonary diseaseAm J Respir Crit Care Med20011641008101111587987
   PubMed Web of Science ®Google Scholar
• DahlMVestboJLangePBojesenSETybjaerg-HansenANordestgaardBGC-reactive protein as a predictor of prognosis in chronic obstructive pulmonary diseaseAm J Respir Crit Care Med200717525025517053205
   PubMed Web of Science ®Google Scholar
• DiCosmoBFGebaGPPicarellaDAirway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivityJ Clin Invest199494202820357962549
   PubMed Web of Science ®Google Scholar
• HierholzerCKalffJCOmertLInterleukin-6 production in hemorrhagic shock is accompanied by neutrophil recruitment and lung injuryAm J Physiol1998275L611L6219728057
   PubMedGoogle Scholar
• JohnstonRASchwartzmanINFlyntLShoreSARole of interleukin-6 in murine airway responses to ozoneAm J Physiol Lung Cell Mol Physiol2005288L390L39715516495
   PubMed Web of Science ®Google Scholar
• KuhnCIIIHomerRJZhuZAirway hyperresponsiveness and airway obstruction in transgenic mice. Morphologic correlates in mice overexpressing interleukin (IL)-11 and IL-6 in the lungAm J Respir Cell Mol Biol20002228929510696065
   PubMed Web of Science ®Google Scholar
• ParkCSChungSWKiSYIncreased levels of interleukin-6 are associated with lymphocytosis in bronchoalveolar lavage fluids of idiopathic nonspecific interstitial pneumoniaAm J Respir Crit Care Med20001621162116810988147
   PubMed Web of Science ®Google Scholar
• RomaniLMencacciACenciEImpaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicansJ Exp Med1996183134513558666893
   PubMed Web of Science ®Google Scholar
• RomanoMSironiMToniattiCRole of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitmentImmunity199763153259075932
   PubMed Web of Science ®Google Scholar
• SuwaTHoggJCKlutMEHardsJvan EedenSFInterleukin-6 changes deformability of neutrophils and induces their sequestration in the lungAm J Respir Crit Care Med200116397097611282775
   PubMed Web of Science ®Google Scholar
• XingZBraciakTJordanaMCroitoruKGrahamFLGauldieJAdenovirus-mediated cytokine gene transfer at tissue sites. Overexpression of IL-6 induces lymphocytic hyperplasia in the lungJ Immunol1994153405940697930613
   PubMed Web of Science ®Google Scholar
• YoshidaMSakumaJHayashiSA histologically distinctive interstitial pneumonia induced by overexpression of the interleukin 6, transforming growth factor beta 1, or platelet-derived growth factor B geneProc Natl Acad Sci U S A199592957095747568174
   PubMed Web of Science ®Google Scholar
• LuisettiMMaSIadarolaPDesmosine as a biomarker of elastin degradation in COPD: current status and future directionsEur Respir J2008321146115718978133
   PubMed Web of Science ®Google Scholar
• KobayashiHKanohSMotoyoshiKSerum surfactant protein-A, but not surfactant protein-D or KL-6, can predict preclinical lung damage induced by smokingBiomarkers20081338539218595202
   PubMed Web of Science ®Google Scholar
• SinDDManSFMarciniukDDThe effects of fluticasone with or without salmeterol on systemic biomarkers of inflammation in chronic obstructive pulmonary diseaseAm J Respir Crit Care Med20081771207121418310480
   PubMed Web of Science ®Google Scholar
• OhlmeierSVuolantoMToljamoTProteomics of human lung tissue identifies surfactant protein a as a marker of chronic obstructive pulmonary diseaseJ Proteome Res2008 (in press, available in on-line version)
   Web of Science ®Google Scholar
• BhattacharyaSSrisumaSDemeoDLMolecular Biomarkers for quantitative and discrete COPD phenotypesAm J Respir Cell Mol Biol2008 (in press, available in on-line version)
   Web of Science ®Google Scholar
• LarssonKInflammatory markers in COPDClin Respir J200828487
   Web of Science ®Google Scholar
• SnellNNewboldPThe clinical utility of biomarkers in asthma and COPDCurr Opin Pharmacol2008822223518468485
   PubMed Web of Science ®Google Scholar