Intravenous ibuprofen: the first injectable product for the treatment of pain and fever

References

• RathmellJPWuCLSinatraRSAcute post-surgical pain management: a critical appraisal of current practice, 2005 Dec 2–4Reg Anesth Pain Med20063114216849098
   PubMed Web of Science ®Google Scholar
• LeeTSIntensive Care anethesia and analgesiaBongardFSSDVintchJRCurrent Diagnosis and Treatment: Critical Care3rd edNew York, NYMcGraw Hill200897116
   Google Scholar
• SouthworthSPetersJRockAPavlivLA multicenter, randomized, double-blind, placebo-controlled trial of intravenous ibuprofen 400 and 800 mg every 6 hours in the management of postoperative painClin Ther2009311922193519843482
   PubMed Web of Science ®Google Scholar
• MiaskowskiCBMChouRD’ArcyYHartwickCHuffmanLMalekiJManwarrenRPrinciples of Analgesic Use in the Treatment of Acute Pain and Cancer Pain6th edNew York, NYAmerican Psychological Society2008
   Google Scholar
• Cancer, pain relief and palliative care. World Health OrganizationGenevaWHO Technical Report Series1990
   Google Scholar
• BertagnolliMMEagleCJZauberAGFive-year efficacy and safety analysis of the Adenoma Prevention with Celecoxib TrialCancer Prev Res20092310321
   PubMed Web of Science ®Google Scholar
• BertagnolliMMEagleCJZauberAGCelecoxib for the prevention of sporadic colorectal adenomasN Engl J Med200635587388416943400
   PubMed Web of Science ®Google Scholar
• RoumieCLChomaNNKaltenbachLMitchelEFJrArbogastPGGriffinMRNon-aspirin NSAIDs, cyclooxygenase-2 inhibitors and risk for cardiovascular events-stroke, acute myocardial infarction, and death from coronary heart diseasePharmacoepidemiol Drug Saf2009181053106319637402
   PubMed Web of Science ®Google Scholar
• ShaferSLRetraction noticeAnesth Analg2009108135119299814
   PubMed Web of Science ®Google Scholar
• VaneJRBottingRMNew insights into the mode of action of anti-inflammatory drugsInflamm Res1995441107664022
   PubMed Web of Science ®Google Scholar
• MarikPEFever in the ICUChest200011785586910713016
   PubMed Web of Science ®Google Scholar
• KauffmanRENelsonMVEffect of age on ibuprofen pharmacokinetics and antipyretic responseJ Pediatr19921219699731447669
   PubMed Web of Science ®Google Scholar
• McIntyreJHullDComparing efficacy and tolerability of ibuprofen and paracetamol in feverArch Dis Child1996741641678660083
   PubMed Web of Science ®Google Scholar
• Toradol [package insert]Nutley, NJRoche Pharmaceuticals2002
   Google Scholar
• AroraSWagnerJGHerbertMMyth: parenteral ketorolac provides more effective analgesia than oral ibuprofenCan J Emerg Med200793032
   Web of Science ®Google Scholar
• ToddPAClissoldSPTenoxicam. An update of its pharmacology and therapeutic efficacy in rheumatic diseasesDrugs1991416256461711963
   PubMed Web of Science ®Google Scholar
• LloydRDerrySMooreRAMcQuayHJIntravenous or intramuscular parecoxib for acute postoperative pain in adultsCochrane Database Syst Rev2009CD00477119370610
   PubMed Web of Science ®Google Scholar
• LeesonRMHarrisonSErnstCCDyloject, a novel injectable diclofenac formulation, offers greater safety and efficacy than voltarol for postoperative dental painReg Anesth Pain Med20073230331017720114
   PubMed Web of Science ®Google Scholar
• Ibuprofen: Martindale – The Complete Drug Reference;2009
   Google Scholar
• Neoprofen [package insert]Deerfield, ILOvation Pharmaceuticals2006
   Google Scholar
• SmythEFitzGeraldGThe eicosanoids: prostaglandins, thromboxanes, leukotrienes, and related compoundsKatzungBBasic and Clinical Pharmacology11th edNew York, NYMcGraw-Hill
   Google Scholar
• FurstDUlrichRVarkey-AltamiranoCNon-steroidal anti-inflammatory drugs, disease modifying antirheumatic drugs, non-opioid analgesics, and drugs used in goutKatzungBBasic and Clinical Pharmacology11th edNew York, NYMcGraw-Hill
   Google Scholar
• BernardGRWheelerAPRussellJAThe effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study GroupN Engl J Med19973369129189070471
   PubMed Web of Science ®Google Scholar
• AronsMMWheelerAPBernardGREffects of ibuprofen on the physiology and survival of hypothermic sepsis. Ibuprofen in Sepsis Study GroupCrit Care Med19992769970710321658
   PubMed Web of Science ®Google Scholar
• Cadolor [package insert]Nashville, TNCumberland Pharmaceuticals2009
   Google Scholar
• BridouxFHazzanMPallotJLAcute renal failure after the use of angiotensin-converting-enzyme inhibitors in patients without renal artery stenosisNephrol Dial Transplant199271001041314966
   PubMed Web of Science ®Google Scholar
• PackerMInteraction of prostaglandins and angiotensin II in the modulation of renal function in congestive heart failureCirculation198877I64732967129
   PubMed Web of Science ®Google Scholar
• BookstaverPBNorrisLRudisillCDeWittTAzizSFantJMultiple toxic effects of low-dose methotrexate in a patient treated for psoriasisAm J Health Syst Pharm2008652117212118997139
   PubMed Web of Science ®Google Scholar
• BrownRDWilsonJTKearnsGLEichlerVFJohnsonVABertrandKMSingle-dose pharmacokinetics of ibuprofen and acetaminophen in febrile childrenJ Clin Pharmacol1992322312411564127
   PubMed Web of Science ®Google Scholar
• KelleyMTWalsonPDEdgeJHCoxSMortensenMEPharmacokinetics and pharmacodynamics of ibuprofen isomers and acetaminophen in febrile childrenClin Pharmacol Ther1992521811891505153
   PubMed Web of Science ®Google Scholar
• AlbertKSGillespieWRWagnerJGPauALockwoodGFEffects of age on the clinical pharmacokinetics of ibuprofenAm J Med19847747506380280
   PubMed Web of Science ®Google Scholar
• WalsonPDMortensenMEPharmacokinetics of common analgesics, anti-inflammatories and antipyretics in childrenClin Pharmacokinet1989171161372692935
   PubMed Web of Science ®Google Scholar
• MorrisPJGuntapalliKWrightPBernardGA multi-center, randomized, double-blind, placebo-controlled trial of the efficacy and safety of intravenous ibuprofen in febrile adultsSociety of Critical Care Medicine Annual CongressHonolulu, HI2008
   Google Scholar
• PavlivLRA randomized, double-blind, placebo-controlled, single dose, crossover study of the pharmacokinetics, safety and tolerability of ibuprofen injection in healthy adult volunteersAmerican Society of Health System Pharmacists Midyear Clinical MeetingLas Vegas, NV2009
   Google Scholar
• Cumberlond PharmaceuticalsEfficacy (fever and pain) and safety study of Caldolor in hospitalized burn patients NCT 00606489; Data on File
   Google Scholar
• WilsonJTBrownRDKearnsGLSingle-dose, placebo-controlled comparative study of ibuprofen and acetaminophen antipyresis in childrenJ Pediatr19911198038111941390
   PubMed Web of Science ®Google Scholar
• KokkiHKumpulainenELehtonenMCerebrospinal fluid distribution of ibuprofen after intravenous administration in childrenPediatrics2007120e1002e100817908721
   PubMed Web of Science ®Google Scholar
• BannwarthBLapicqueFPehourcqFStereoselective disposition of ibuprofen enantiomers in human cerebrospinal fluidBr J Clin Pharmacol1995402662698527289
   PubMed Web of Science ®Google Scholar
• BarbatoFLa RotondaMIQuagliaFInteractions of nonsteroidal antiinflammatory drugs with phospholipids: comparison between octanol/buffer partition coefficients and chromatographic indexes on immobilized artificial membranesJ Pharm Sci1997862252299040100
   PubMed Web of Science ®Google Scholar
• LeeGDallasSHongMBendayanRDrug transporters in the central nervous system: brain barriers and brain parenchyma considerationsPharmacol Rev20015356959611734619
   PubMed Web of Science ®Google Scholar
• KhamdangSTakedaMNoshiroRInteractions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugsJ Pharmacol Exp Ther200230353453912388633
   PubMed Web of Science ®Google Scholar
• BodoABakosESzeriFVaradiASarkadiBThe role of multidrug transporters in drug availability, metabolism and toxicityToxicol Lett2003140141133143
   Web of Science ®Google Scholar
• MannilaAKokkiHHeikkinenMCerebrospinal fluid distribution of ketoprofen after intravenous administration in young childrenClin Pharmacokinet20064573774316802854
   PubMed Web of Science ®Google Scholar
• MannilaAKumpulainenELehtonenMPlasma and cerebrospinal fluid concentrations of indomethacin in children after intravenous administrationJ Clin Pharmacol2007479410017192507
   PubMed Web of Science ®Google Scholar
• HanEEBeringerPMLouieSGGillMAShapiroBJPharmacokinetics of Ibuprofen in children with cystic fibrosisClin Pharmacokinet20044314515614871154
   PubMed Web of Science ®Google Scholar
• KonstanMWHoppelCLChaiBLDavisPBIbuprofen in children with cystic fibrosis: pharmacokinetics and adverse effectsJ Pediatr19911189569642040934
   PubMed Web of Science ®Google Scholar
• Cumberlond PharmaceuticalsConcentration/Stability in Diluents; Data on File
   Google Scholar
• Cumberlond PharmaceuticalsA Multi-Center, Randomized, Double Blind, Placebo Controlled Trial of Ibuprofen Injection for treatment of pain in post-operative adult patients (abdominal hysterectomy pain study); Data on File
   Google Scholar
• KrollPMLRockAKaelinBPavlivLIntravenous ibuprofen for the management of postoperative pain in adultsAmerican Academy of Pain Management Annual MeetingPhoenix, AZ2009
   Google Scholar
• Cumberlond PharmaceuticalsNCT00470600, Efficacy and Safety Study of Caldolor in Hospitalized Adult Orthopedic Patients; Data on File
   Google Scholar
• Caldolor injection demonstrates significant fever reduction in hospitalized burn patients http://www.medicalnewstoday.com/articles/171906.php Accessed Jan 5, 2010.
   Google Scholar
• GurfinkelEPGuerlloyFPMautnerBSuppression of life-threatening tachyarrhyhmias, and atrioventricular ischemic block following the administration of anti-inflammatory intravenous drugInt J Cardiol2007114E56E5717067695
   PubMedGoogle Scholar
• Van OvermeireBSmetsKLecoutereDA comparison of ibuprofen and indomethacin for closure of patent ductus arteriosusN Engl J Med200034367468110974130
   PubMed Web of Science ®Google Scholar
• LagoPBettiolTSalvadoriSSafety and efficacy of ibuprofen versus indomethacin in preterm infants treated for patent ductus arteriosus: a randomised controlled trialEur J Pediatr200216120220712014386
   PubMed Web of Science ®Google Scholar
• CherifAKhroufNJabnounSRandomized pilot study comparing oral ibuprofen with intravenous ibuprofen in very low birth weight infants with patent ductus arteriosusPediatrics2008122e1256e126119047225
   PubMed Web of Science ®Google Scholar
• Cumberlond PharmaceuticalsNCT00606489, Efficacy (fever and pain) and safety of Caldolor in hospitalized burn patients; Data on File
   Google Scholar
• AronoffDMBlochKCAssessing the relationship between the use of nonsteroidal antiinflammatory drugs and necrotizing fasciitis caused by group A streptococcusMedicine (Baltimore)20038222523512861100
   PubMed Web of Science ®Google Scholar
• SouyriCOlivierPGrolleauSLapeyre-MestreMSevere necrotizing soft-tissue infections and nonsteroidal anti-inflammatory drugsClin Exp Dermatol20083324925518261144
   PubMed Web of Science ®Google Scholar
• FactorSHLevineOSHarrisonLHRisk factors for pediatric invasive group A streptococcal diseaseEmerg Infect Dis2005111062106616022781
   PubMed Web of Science ®Google Scholar
• PetersonCLVugiaDJMeyersHBRisk factors for invasive group A streptococcal infections in children with varicella: a case-control studyPediatr Infect Dis J1996151511568822289
   PubMed Web of Science ®Google Scholar
• ZerrDMAlexanderERDuchinJSKoutskyLARubensCEA case-control study of necrotizing fasciitis during primary varicellaPediatrics199910378379010103303
   PubMed Web of Science ®Google Scholar
• AronoffDMNeilsonEGAntipyretics: mechanisms of action and clinical use in fever suppressionAm J Med200111130431511566461
   PubMed Web of Science ®Google Scholar
• BarnhamMNonsteroidal antiinflammatory drugs: concurrent or causative drugs in serious infection?Clin Infect Dis199725127212739402413
   PubMed Web of Science ®Google Scholar
• AllenHLWaseABearWTIndomethacin and aspirin: effect of non-steroidal anti-inflammatory agents on the rate of fracture repair in the ratActa Orthop Scand1980515956007446048
   PubMed Web of Science ®Google Scholar
• AltmanRDLattaLLKeerRRenfreeKHornicekFJBanovacKEffect of nonsteroidal antiinflammatory drugs on fracture healing: a laboratory study in ratsJ Orthop Trauma199593924008537842
   PubMed Web of Science ®Google Scholar
• GoodmanSMaTTrindadeMCOX-2 selective NSAID decreases bone ingrowth in vivoJ Orthop Res2002201164116912472224
   PubMed Web of Science ®Google Scholar
• WolfeMMLichtensteinDRSinghGGastrointestinal toxicity of non-steroidal antiinflammatory drugsN Engl J Med19993401888189910369853
   PubMed Web of Science ®Google Scholar