References
- AllemannELerouxJ-CGurnyRPolymeric nano- and microparticles for the oral delivery of peptides and peptidomimeticsAdv Drug Deliv Rev1998341718910837677
- ArturssonPLindmarkTDavisSSEffect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2)Pharm Res1994111358617816770
- BaconAMakinJSizerPJCarbohydrate biopolymers enhance antibody responses to mucosally delivered vaccine antigensInfect Immun20006857647010992483
- BehrensIPenaAIAlonsoMJComparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and transportPharm Res20021911859312240945
- Bernkop-SchnürchAKrajicekMEMucoadhesive polymers as platforms for peroral peptide delivery and absorption: synthesis and evaluation of different chitosan-EDTA conjugatesJ Control Release199850215239685888
- Bernkop-SchnürchAScerbe-SaikoASynthesis and in vitro evaluation of chitosan-EDTA-protease-inhibitor conjugates which might be useful in oral delivery of peptides and proteinsPharm Res19981526399523313
- Bernkop-SchnürchAChitosan and its derivatives: potential excipients for peroral peptide delivery systemsInt J Pharm200019411310601680
- Bernkop-SchnürchAKastCEGuggiDPermeation enhancing polymers in oral delivery of hydrophilic macromolecules: thiomer/GSH systemsJ Control Release20039395103
- Bernkop-SchnürchAGuggiDPinterYThiolated chitosans: development and in vitro evaluation of a mucoadhesive, permeation enhancing oral drug delivery systemJ Control Release2004941778614684281
- Bivas-BenitaMLaloupMVersteyheSGeneration of Toxoplasma gondii GRA1 protein and DNA vaccine loaded chitosan particles: preparation, characterization, and preliminary in vivo studiesInt J Pharm2003266172714559390
- BowmanKSarkarRRautSOral delivery of non-viral DNA nanoparticles for hemophilia A. American Society of Gene Therapy, 8th Annual Meeting [abstract]Mol Ther200511(Suppl 1) Abs 779
- ChellatFGrandjean-LaquerriereALe NaourRMetalloproteinase and cytokine production by THP-1 macrophages following exposure to chitosan-DNA nanoparticlesBiomaterials2005269617015369684
- ChenJYangWLLiGTransfection of mEpo gene to intestinal epithelium in vivo mediated by oral delivery of chitosan-DNA nanoparticlesWorld J Gastroenterol2004101121614695780
- CheungCYMurthyNStaytonPSA pH-sensitive polymer that enhances cationic lipid-mediated gene transferBioconjug Chem2001129061011716680
- ChewJLWolfowiczCBMaoHQChitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in miceVaccine2003212720912798609
- ClarkMAJepsonMAHirstBHExploiting M cells for drug and vaccine deliveryAdv Drug Deliv Rev2001508110611489335
- DeaconMPMcGurkSRobertsCJAtomic force microscopy of gastric mucin and chitosan mucoadhesive systemsBiochem J20003485576310839986
- DesaiMPLabhasetwarVAmidonGLGastrointestinal uptake of biodegradable microparticles: effect of particle sizePharm Res1996131838458987081
- DesaiMPLabhasetwarVWalterEThe mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependentPharm Res1997141568739434276
- DhawanSSinglaAKSinhaVREvaluation of mucoadhesive properties of chitosan microspheres prepared by different methodsAAPS PharmSciTech20046717 5 article
- DodaneVKhanMAMerwinJREffect of chitosan on epithelial permeability and structureInt J Pharm1999182213210332071
- EldridgeJHHammondCJMeulbroekJAControlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the Peyer’s patchesJ Control Release19901120514
- El-ShabouriMHPositively charged nanoparticles for improving the oral bioavailability of cyclosporin-AInt J Pharm2002249101812433438
- FangNChanVMaoH-QInteractions of phospholipid bilayer with chitosan: effect of molecular weight and pHBiomacromolecules200121161811777388
- Fernandez-UrrusunoRCalvoPRemunan-LopezCEnhancement of nasal absorption of insulin using chitosan nanoparticlesPharm Res19991615768110554100
- GaoSChenJXuXGalactosylated low molecular weight chitosan as DNA carrier for hepatocyte-targetingInt J Pharm2003255576812672602
- GoldbergMGomez-OrellanaIChallenges for the oral delivery of macromoleculesNat Rev Drug Discov200322899512669028
- HejaziRAmijiMChitosan-based gastrointestinal delivery systemsJ Control Release2003891516512711440
- HiranoSChitin biotechnology applicationsBiotechnol Annu Rev19962237589704098
- HuangMFongCWKhorETransfection efficiency of chitosan vectors: Effect of polymer molecular weight and degree of deacetylationJ Control Release200510639140615967533
- JepsonMAClarkMAFosterNTargeting to intestinal M cellsJ Anat1996189507168982824
- KafedjiiskiKHofferMWerleMImproved synthesis and in vitro characterization of chitosan–thioethylamidine conjugateBiomaterials2006271273516045983
- KiangTWenJLimHWThe effect of the degree of chitosan deacetylation on the efficiency of gene transfectionBiomaterials200425529330115110480
- KiangTBrightCCheungCYFormulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expressionBiomater Sci Polym Ed200415140521
- KimTHParkIKNahJWGalactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrierBiomaterials20042537839215020154
- KimTHKimSIAkaikeTSynergistic effect of poly(ethylenimine) on the transfection efficiency of galactosylated chitosan/DNA complexesJ Control Release20051053546615949861
- KockischSReesGDYoungSAPolymeric microspheres for drug delivery to the oral cavity: an in vitro evaluation of mucoadhesive potentialJ Pharm Sci20039216142312884248
- Köping-HöggårdMVårumKMIssaMImproved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomersGene Ther20041114415215269712
- KotzéAFThanouMMLueBenHLEnhancement of paracellular drug transport with highly quaternized N-trimethyl chitosan chloride in neutral environments: in vitro evaluation in intestinal epithelial cells (Caco-2)J Pharm Sci19998825379950647
- KriegAMImmune effects and mechanisms of action of CpG motifsVaccine2001196182211090712
- LeitnerWWYingHRestifoNPDNA and RNA-based vaccines: principles, progress and prospectsVaccine2000187657710580187
- LeongKWMaoHQTruong-LeVLDNA-polycation nanospheres as non-viral gene delivery vehiclesJ Control Release199853183939741926
- LiuWSunSCaoZAn investigation on the physicochemical properties of chitosan/DNA polyelectrolyte complexesBiomaterials20052627051115585274
- LueBenHLde LeeuwBJLangemeyerMWMucoadhesive polymers in peroral peptide drug delivery. VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivoPharm Res1996131668728956332
- LueBenHLde LeeuwBJLangemeyerMWMucoadhesive polymers in peroral peptide drug delivery. IV. Polycarbophil and chitosan are potent enhancers of peptide transport across intestinal mucosae in vitroJ Control Release1997451523
- MaZLimL-YUptake of chitosan and associated insulin in Caco-2 cell monolayers: a comparison between chitosan molecules and chitosan nanoparticlesPharm Res20032018121914661926
- MaZLimTMLimL-YPharmacological activity of peroral chitosan-insulin nanoparticles in diabetic ratsInt J Pharm20052932718015778065
- MacLaughlinFCMumperRJWangJChitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid deliveryJ Control Release199856259729801449
- MaoH-QRoyKTroung-LeVLChitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiencyJ Control Release20017039942111182210
- MaoSShuaiXUngerFThe depolymerization of chitosan: effects on physicochemical and biological propertiesInt J Pharm2004281455415288342
- NeutraMRPhillipsTLMayerELTransport of membrane-bound macromolecules by M cells in follicle-associated epithelium of rabbit Peyer’s patchCell Tissue Res1987247537463568100
- OkoliGHortelanoGLeongKWOral delivery of plasmid DNA encoding the factor IX gene [abstract]Proceed Intl Symp Control Rel Bioact Mater200027 Abs 234
- OtterleiMVårumKMRyanLCharacterization of binding and TNF-A-inducing ability of chitosans on monocytes: the involvement of CD14Vaccine199412825327526573
- PanYLiYJZhaoHYBioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivoInt J Pharm20022491394712433442
- PregoCGarciaMTorresDTransmucosal macromolecular drug deliveryJ Control Release20051011516215588901
- RenDYiHWangWThe enzymatic degradation and swelling properties of chitosan matrices with different degrees of N-acetylationCarbohydr Res200534024031016109386
- RoyKMaoHQHuangSKOral gene delivery with chitosan--DNA nanoparticles generates immunologic protection in a murine model of peanut allergyNat Med199953879110202926
- SchipperNGVårumKMArturssonPChitosans as absorption enhancers for poorly absorbable drugs. 1: Influence of molecular weight and degree of acetylation on drug transport across human intestinal epithelial (Caco-2) cellsPharm Res1996131686928956335
- SchipperNGOlssonSHoogstraateJAChitosans as absorption enhancers for poorly absorbable drugs 2: mechanism of absorption enhancementPharm Res19971492399244151
- SchipperNGVårumKMStenbergPChitosans as absorption enhancers of poorly absorbable drugs. 3: Influence of mucus on absorption enhancementEur J Pharm Sci199983354310425384
- SheuERothmanSGermanMThe “Gene Pill” and its therapeutic applicationsCurr Opin Mol Ther20035420714513686
- ShibataYFosterLAMetzgerWJAlveolar macrophage priming by intravenous administration of chitin particles, polymers of N-acetyl-D-glucosamine, in miceInfect Immun1997651734419125555
- SinglaAKChawlaMChitosan: some pharmaceutical and biological aspects- an updateJ Pharm Pharmacol20015310476711518015
- SnymanDHammanJHKotzéAFEvaluation of the mucoadhesive properties of N-trimethyl chitosan chlorideDrug Dev Ind Pharm20032961912602493
- TakeuchiHMatsuiYSugiharaHEffectiveness of submicron-sized, chitosan-coated liposomes in oral administration of peptide drugsInt J Pharm20053031607016125348
- ThanouMVerhoefJCMarbachPIntestinal absorption of octreotide: N-trimethyl chitosan chloride (TMC) ameliorates the permeability and absorption properties of the somatostatin analogue in vitro and in vivoJ Pharm Sci200089951710861597
- ThanouMVerhoefJCJungingerHEChitosan and its derivatives as intestinal absorption enhancersAdv Drug Deliv Rev200150S9110111576697
- ThanouMVerhoefJCVerheijdenJHMIntestinal absorption of octreotide using trimethyl chitosan chloride: studies in pigsPharm Res200118823811474787
- van der MerweSMVerhoefJCVerheijdenJHMTrimethylated chitosan as polymeric absorption enhancer for improved peroral delivery of peptide drugsEur J Pharm Biopharm2004582253515296951
- WangJTauchiYDeguchiYPositively charged gelatin microspheres as gastric mucoadhesive drug delivery system for eradication of H. pyloriDrug Deliv200072374311195431
- ZhangHNeauSHIn vitro degradation of chitosan by a commercial enzyme preparation: effect of molecular weight and degree of deacetylationBiomaterials2001221653811374467
- ZhangHNeauSHIn vitro degradation of chitosan by bacterial enzymes from rat cecal and colonic contentsBiomaterials2002232761612059026