341
Views
20
CrossRef citations to date
0
Altmetric
Review

Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management

&
Pages 209-218 | Published online: 01 Jun 2010

References

  • SequistLVProtein degradation/chaperone system and histone deacetylase pathwayJ Thorac Oncol2009411 Suppl 3S1077S107819861924
  • World Health OrganizationInternational Statistical Classification of Diseases and Related Health Problems; Tenth edition (ICD-10)Geneva, SwitzerlandWorld Health Organization1992
  • DemeesterKvan WieringenAHendrickxJJPrevalence of tinnitus and audiometric shapeB-ENT20073Suppl 7374918225607
  • AdogaAAAdogaASObindoJTTinnitus and the prevalence of co-morbid psychological stressNiger J Med2008171959718390143
  • SieKCRubelEWRapid changes in protein synthesis and cell size in the cochlear nucleus following eighth nerve activity blockade or cochlea ablationJ Comp Neurol199232045015081629400
  • TzounopoulosTMechanisms of synaptic plasticity in the dorsal cochlear nucleus:plasticity-induced changes that could underlie tinnitusAm J Audiol2008172S170S17518978197
  • HanBILeeHWKimTYLimJSShinKSTinnitus:characteristics causes mechanisms and treatmentsJ Clin Neurol200951111919513328
  • KempDTStimulated acoustic emissions from within the human auditory systemJ Acoust Soc Am19786413861391744838
  • KiangNYMoxonECLevineRAAuditory-nerve activity in cats with normal and abnormal cochleasSensorineural Hearing LossChicherter, West SussexWiley Ciba Found Symp1970241273
  • JastreboffPJHazellJWA neurophysiological approach to tinnitus:clinical implicationsBr J Audiol1993277178339063
  • KaltenbachJAZhangJFinlaysonPTinnitus as a plastic phenomenon and its possible neural underpinnings in the dorsal cochlear nucleusHear Res200520620022616081009
  • SalviRJWangJDingDAuditory plasticity and hyperactivity following cochlear damageHear Res200014726127410962190
  • MøllerARPathophysiology of tinnitusAnn Otol Rhinol Laryngol19849339446367601
  • LevineRASomatic (craniocervical) tinnitus and the dorsal cochlear nucleus hypothesisAm J Otolaryngol19992035136210609479
  • LingLLHughesLFCasparyDMAge-related loss of the GABA synthetic enzyme glutamic acid decarboxylase in rat primary auditory cortexNeuroscience200513241103111315857714
  • CamposMLde CaboCWisdenWJuizJMMerloDExpression of GABA(A) receptor subunits in rat brainstem auditory pathways:cochlear nuclei superior olivary complex and nucleus of the lateral lemniscusNeuroscience2001102362563811226699
  • RosenhallUKarlssonAKTinnitus in old ageScand Audiol19912031651711842285
  • DiazSLBarrosVGAntonelliMCRubioMCBalerioGNMorphine withdrawal syndrome and its prevention with baclofen: Autoradiographic study of mu-opioid receptors in prepubertal male and female miceSynapse200660213214016715492
  • BrozoskiTJSpiresTJBauerCAVigabatrin a GABA transaminase inhibitor reversibly eliminates tinnitus in an animal modelJ Assoc Res Otolaryngol20078110511817221143
  • ShulmanAGabapentin and tinnitus reliefInt Tinnitus J20081411518616079
  • YangGLobarinasEZhangLSalicylate-induced tinnitus:behavioral measures and neural activity in auditory cortex of awake ratsHear Res20072261–224425316904853
  • TylerRSCoelhoCNobleWTinnitus: standard of care, personality differences, genetic factorsORL J Otorhinolaryngol Relat Spec20066811419 discussion 20–2.16514258
  • FolmerRLShiYBSSRI use by tinnitus patients:interactions between depression and tinnitus severityEar Nose Throat J200483210711215008444
  • LockwoodAHSalviRJCoadMLTowsleyMLWackDSMurphyBWThe functional neuroanatomy of tinnitus:evidence for limbic system links and neural plasticityNeurology19985011141209443467
  • BrunoniARLopesMFregniFA systematic review and meta-analysis of clinical studies on major depression and BDNF levels:implications for the role of neuroplasticity in depressionInt J Neuropsychopharmacol20081181169118018752720
  • TanJRüttigerLPanford-WalshRTinnitus behavior and hearing function correlate with the reciprocal expression patterns of BDNF and Arg3.1/arc in auditory neurons following acoustic traumaNeuroscience2007145271572617275194
  • MollerARTinnitus and painProg Brain Res2007166475317956770
  • PuelJLCochlear NMDA receptor blockade prevents salicylate-induced tinnitusB-ENT20073Suppl 7192218225604
  • GuittonMJCastonJRuelJJohnsonRMPujolRPuelJLSalicylate induces tinnitus through activation of cochlear NMDA receptorsJ Neurosci20032393944395212736364
  • GuittonMJDudaiYBlockade of cochlear NMDA receptors prevents long-term tinnitus during a brief consolidation window after acoustic traumaNeural Plast200720078090418301716
  • PomaraNOttBRPeskindEResnickEMMemantine treatment of cognitive symptoms in mild to moderate Alzheimer disease:secondary analyses from a placebo-controlled randomized trialAlzheimer Dis Assoc Disord2007211606417334274
  • OliverDLudwigJReisingerEZoellnerWRuppersbergJPFaklerBMemantine inhibits efferent cholinergic transmission in the cochlea by blocking nicotinic acetylcholine receptors of outer hair cellsMol Pharmacol200160118318911408613
  • MasonBJTreatment of alcohol-dependent outpatients with acamprosate:a clinical reviewJ Clin Psychiatry200162Suppl 20424811584875
  • MannKKieferFSpanagelRLittletonJAcamprosate: Recent findings and future research directionsAlcohol Clin Exp Res20083271105111018540918
  • AzevedoAAFigueiredoRRTinnitus treatment with acamprosate: double-blind studyBraz J Otorhinolaryngol200571561862316612523
  • PengBGChenSLinXAspirin selectively augmented N-methyl-D-aspartate types of glutamate responses in cultured spiral ganglion neurons of miceNeurosci Lett20033431212412749988
  • PuelJLRuelJGervaisd’Aldin CPujolRExcitotoxicity and repair of cochlear synapses after noise-trauma induced hearing lossNeuroreport199899210921149674603
  • MulySMGrossJSPotashnerSJNoise trauma alters D-[3H]aspartate release and AMPA binding in chinchilla cochlear nucleusJ Neurosci Res200475458559614743442
  • GuittonMJPujolRPuelJLm-Chlorophenylpiperazine exacerbates perception of salicylate-induced tinnitus in ratsEur J Neurosci200522102675267816307611
  • WeiseCHeineckeKRiefWStability of physiological variables in chronic tinnitus sufferersAppl Psychophysiol Biofeedback200833314915918600443
  • SziklaiIThe significance of the calcium signal in the outer hair cells and its possible role in tinnitus of cochlear originEur Arch Otorhinolaryngol20042611051752515609110
  • NarváezMFiguerasACapellàDLaporteJRTinnitus with calcium-channel blockersLancet1994343890712291230
  • PuelJLGuittonMJSalicylate-induced tinnitus:molecular mechanisms and modulation by anxietyProg Brain Res200716614114617956778
  • EggermontJJTinnitus:neurobiological substratesDrug Discov Today200510191283129016214672
  • ElgoyhenABKatzEFuchsPAThe nicotinic receptor of cochlear hair cells:a possible pharmacotherapeutic target?Biochem Pharmacol200978771271919481062
  • Jimenez-RuizCBerlinIHeringTVarenicline:a novel pharmaco-therapy for smoking cessationDrugs200969101319133819583451
  • BaldoPDoreeCLazzariniRMolinPMcFerranDJAntide-pressants for patients with tinnitusCochrane Database Syst Rev20064CD00385317054188
  • RobinsonSAntidepressants for treatment of tinnitusProg Brain Res200716626327117956790
  • DobieRADepression and tinnitusOtolaryngol Clin North Am200336238338812856305
  • ChandraRKEpsteinVAFishmanAJPrevalence of depression and antidepressant use in an otolaryngology patient populationOtolaryngol Head Neck Surg2009141113613819559973
  • SullivanMKatonWRussoJDobieRSakaiCA randomized trial of nortriptyline for severe chronic tinnitus. Effects on depression disability and tinnitus symptomsArch Intern Med199315319225122598215728
  • DobieRASakaiCSSullivanMDKatonWJRussoJAntidepressant treatment of tinnitus patients:report of a randomized clinical trial and clinical prediction of benefitAm J Otol199314118238424470
  • DobieRASakaiCSSullivanMDKatonWJRussoJAntidepressant treatment of tinnitus patients. Interim report of a randomized clinical trialActa Otolaryngol199211222422471604987
  • EvansDLGoldenRNProtriptyline and tinnitusJ Clin Psychopharmacol1981164044067334152
  • GoldenRNEvansDLNauCHDoxepin and tinnitusSouth Med J1983769120412056612411
  • MihailRCCrowleyJMWaldenBEFishburneJReinwallJEZajtchukJTThe tricyclic trimipramine in the treatment of subjective tinnitusAnn Otol Rhinol Laryngol1988972 Pt 11201233355041
  • AckermanDLGreenlandSBystritskyAKatzRJRelationship between early side effects and therapeutic effects of clomipramine therapy in obsessive-compulsive disorderJ Clin Psychopharmacol19961643243288835709
  • MendisDJohnstonMAn unusual case of prolonged tinnitus following low-dose amitriptylineJ Psychopharmacol200822557457518308819
  • PodoshinLBen-DavidYFradisMMalatskeySHafnerHIdiopathic subjective tinnitus treated by amitriptyline hydrochloride/biofeedbackInt Tinnitus J199511546010753321
  • BayarNBökeBTuranEBelginEEfficacy of amitriptyline in the treatment of subjective tinnitusJ Otolaryngol200130530030311771024
  • DibGCKasseCAAlves de AndradeTGurgel TestaJRCruzOLTinnitus treatment with trazodoneBraz J Otorhinolaryngol200773339039717684661
  • MaraisJCochleotoxicity due to mianserin hydrochlorideJ Laryngol Otol199110564754762072020
  • ZogerSSvedlundJHolgersKMThe effects of sertraline on severe tinnitus suffering--a randomized double-blind placebo-controlled studyJ Clin Psychopharmacol2006261323916415703
  • LeiterFLNierenbergAASandersKMSternTADiscontinuation reactions following sertralineBiol Psychiatry199538106946958555382
  • RobinsonSKViirreESBaileyKAGerkeMAHarrisJPSteinMBRandomized placebo-controlled trial of a selective serotonin reuptake inhibitor in the treatment of nondepressed tinnitus subjectsPsychosom Med200567698198816314604
  • ShemenLFluoxetine for treatment of tinnitusOtolaryngol Head Neck Surg19981183 Pt 14219527133
  • PondromMFBrahmNCVenlafaxine-associated tinnitusAm J Health Syst Pharm200966181606160819729562
  • AhmadSVenlafaxine and severe tinnitusAm Fam Physician19955181830
  • De MarinisMSantilliVTinnitus in postherpetic neuralgiaJ Headache Pain2010111838419851823
  • HummaLMSwimsMPBupropion mimics a transient ischemic attackAnn Pharmacother199933330530710200854
  • SettleECTinnitus related to bupropion treatmentJ Clin Psychiatry19915283521907965
  • D’AmelioRDelbWComorbidity of schizophrenic psychosis and tinnitus. A hitherto neglected theme in research and therapyHNO200856767067218566784
  • Lopez-GonzalezMAMoliner-PeiroFAlfaro-GarciaJEsteban-OrtegaFSulpiride plus hydroxyzine decrease tinnitus perceptionAuris Nasus Larynx2007341232717118597
  • Lopez-GonzalezMASantiagoAMEsteban-OrtegaFSulpiride and melatonin decrease tinnitus perception modulating the auditolimbic dopaminergic pathwayJ Otolaryngol200736421321917942035
  • NeriGBaffaCDe StefanoAManagement of tinnitus:oral treatment with melatonin and sulodexideJ Biol Regul Homeost Agents200923210311019589291
  • OwenRTAgomelatine: A novel pharmacological approach to treating depressionDrugs Today (Barc)200945859960819927226
  • HulshofJHVermeijPThe value of carbamazepine in the treatment of tinnitusORL J Otorhinolaryngol Relat Spec19854752622663900856
  • SanchezTGBalbaniAPBittarRSBentoRFCâmaraJLidocaine test in patients with tinnitus:rationale of accomplishment and relation to the treatment with carbamazepineAuris Nasus Larynx199926441141710530736
  • ZhengYHootonKSmithPFDarlingtonCLCarbamazepine reduces the behavioural manifestations of tinnitus following salicylate treatment in ratsActa Otolaryngol20081281485217851905
  • SheWDaiYDuXChenFDingXCuiXTreatment of subjective tinnitus:a comparative clinical study of intratympanic steroid injection vs. oral carbamazepineMed Sci Monit2009156PI35P13919478715
  • LevineRATypewriter tinnitus:a carbamazepine-responsive syndrome related to auditory nerve vascular compressionORL J Otorhinolaryngol Relat Spec2006681434716514262
  • BrantbergKParoxysmal staccato tinnitus:a carbamazepine responsive hyperactivity dysfunction symptom of the eighth cranial nerveJ Neurol Neurosurg Psychiatry201081445145519778910
  • MansbachALFreyensPTinnitus:current data and treatment with sodium valproateActa Otorhinolaryngol Belg19833756977056419539
  • MenkesDBLarsonPMSodium valproate for tinnitusJ Neurol Neurosurg Psychiatry19986558039810969
  • HoriAKataokaSSakaiKValproic acid-induced hearing loss and tinnitusIntern Med200342111153115414686762
  • YildirimCYağizRUzunCTaşABulutEKarasalihoğluAThe protective effect of oral magnesium supplement on noise-induced hearing lossKulak Burun Bogaz Ihtis Derg2006161293616763412
  • ReevesRRMustainDWPendarvisJEValproate-induced tinnitus misinterpreted as psychotic symptomsSouth Med J200093101030103111147471
  • SimpsonJJGilbertAMWeinerGMDaviesWEThe assessment of lamotrigine an antiepileptic drug in the treatment of tinnitusAm J Otol199920562763110503585
  • BauerCABrozoskiTJEffect of gabapentin on the sensation and impact of tinnitusLaryngoscope2006116567568116652071
  • WitsellDLHannleyMTStinnetSTucciDLTreatment of tinnitus with gabapentin:a pilot studyOtol Neurotol2007281111517106432
  • PiccirilloJFFinnellJVlahiotisACholeRASpitznagelEJrRelief of idiopathic subjective tinnitus:is gabapentin effective?Arch Otolaryngol Head Neck Surg2007133439039717438255
  • BakhshaeeMGhasemiMAzarpazhoohMGabapentin effectiveness on the sensation of subjective idiopathic tinnitus:a pilot studyEur Arch Otorhinolaryngol2008265552553017960408
  • DaviesEKnoxEDonaldsonIThe usefulness of nimodipine an L-calcium channel antagonist in the treatment of tinnitusBr J Audiol19942831251297841896
  • PlengeUMollerAMDevelopment of sustained vasodilatory shock and permanent loss of hearing after severe lithium carbonate poisoningUgeskr Laeger2008170535418252169
  • HobaraTUchidaSOtsukiKAltered gene expression of histone deacetylases in mood disorder patientsJ Psychiatr Res201044526327019767015
  • HallACBrennanAGooldRGValproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neuronsMol Cell Neurosci200220225727012093158
  • DaftaryAShulmanAStrashunAMGottschalkCZoghbiSSSeibylJPBenzodiazepine receptor distribution in severe intractable tinnitusInt Tinnitus J2004101172315379343
  • BahmadFMVenosaAROliveiraCABenzodiazepines and GABAergics in treating severe disabling tinnitus of predominantly cochlear originInt Tinnitus J200612214014417260879
  • JalaliMMKoushaANaghaviSESoleimaniRBananRThe effects of alprazolam on tinnitus:a cross-over randomized clinical trialMed Sci Monit20091511PI55P16019865063
  • Panford-WalshRSingerWRüttigerLMidazolam reverses salicylate-induced changes in brain-derived neurotrophic factor and arg3.1 expression:implications for tinnitus perception and auditory plasticityMol Pharmacol200874359560418524887
  • GanançaMMCaovillaHHGanançaFFClonazepam in the pharmacological treatment of vertigo and tinnitusInt Tinnitus J200281505314763236
  • AlbertinoSAssuncaoARSouzaJAPulsatile tinnitus:treatment with clonazepam and propranololBraz J Otorhinolaryngol200571111111316446904
  • SzczepaniakWSMollerAREffects of (-)-baclofen clonazepam and diazepam on tone exposure-induced hyperexcitability of the inferior colliculus in the rat:possible therapeutic implications for pharmacological management of tinnitus and hyperacusisHear Res1996971–246538844185
  • BustoUFornazzariLNaranjoCAProtracted tinnitus after discontinuation of long-term therapeutic use of benzodiazepinesJ Clin Psychopharmacol1988853593622903182
  • BustoUSellersEMNaranjoCACappellHSanchez-CraigMSykoraKWithdrawal reaction after long-term therapeutic use of benzodiazepinesN Engl J Med1986315148548593092053
  • CoelhoCBTylerRHansenMZinc as a possible treatment for tinnitusProg Brain Res200716627928517956792
  • UedaSTreatment of tinnitus with intravenous lidocaineNippon Jibiinkoka Gakkai Kaiho1992959138913971403327
  • LáinezMJPiera Botulinum toxin for the treatment of somatic tinnitusProg Brain Res200716633533817956797
  • EnricoPSircaDMereuMAntioxidants minerals vitamins and herbal remedies in tinnitus therapyProg Brain Res200716632333017956795
  • DelbWD’AmelioRBoistenCJPlinkertPKEvaluation of the tinnitus retraining therapy as combined with a cognitive behavioral group therapyHNO20025011997100412420185