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Pharmacological manipulation of cyclic GMP levels in brain restores learning ability in animal models of hepatic encephalopathy: therapeutic implications

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Pages 53-63 | Published online: 25 Nov 2022

References

  • AguilarMAMinarroJFelipoV2000Chronic moderate hyperammonemia impairs active and passive avoidance behavior and conditional discrimination learning in ratsExp Neurol1617041310686089
  • AmodioPQueroJCDel PiccoloF1996Diagnostic tools for the detection of subclinical hepatic encephalopathy:comparison of standard and computerized psychometric tests with spectral-EEGMetab Brain Dis11315278979251
  • AmodioPDel PiccoloFMarchettiP1999Clinical features and survival of cirrhotic patients with subclinical cognitive alterations detected by the number connection test and computerized psychometric testsHepatology291662710347105
  • AmodioPMarchettiPDel PiccoloF1999Spectral versus visual EEG analysis in mild hepatic encephalopathyClin Neurophysiol11013344410454268
  • AmodioPDel PiccoloFPettenoE2001Prevalence and prognostic value of quantified electroencephalogram (EEG) alterations in cirrhotic patientsJ Hepatol35374511495040
  • AmodioPMontagneseSGattaA2004Characteristics of minimal hepatic encephalopathyMetab Brain Dis192536715554421
  • ApelqvistGHindfeltBAnderssonG1998Diurnal and gender effects by chronic portacaval shunting in rats on spontaneous locomotor and rearing activities in an open-fieldBehav Brain Res9325329659983
  • ApelqvistGHindfeltBAnderssonG1999Altered adaptive behaviour expressed in an open-field paradigm in experimental hepatic encephalopathyBehav Brain Res1061657310595432
  • AzorinIMinanaMDFelipoV1989A simple animal model of hyperammonemiaHepatology10311142759549
  • BengtssonFNobinAFalckB1986Portacaval shunt in the rat: selective alterations in behavior and brain serotoninPharmacol Biochem Behav241611162426719
  • BengstssonFBuggeMHallH1989Brain 5-HT1 and 5-HT2 binding sites following portacaval shunt in the ratRes Exp Med18924956
  • BernabeuRSchmitzPFaillaceM1996Hippocampal cGMP and cAMP are differentially involved in memory processing of inhibitor avoidance learningNeuroreport758588730835
  • BernabeuRSchroderNQuevedoJ1997Further evidence for the involvement of a hippocampal cGMP/cGMP-dependent protein kinase cascade in memory consolidationNeuroreport8222149243615
  • ChanCYHuangSWWangTF2004Lack of detrimental effects of nitric oxide inhibition in bile duct-ligated rats with hepatic encephalopathyEur J Clin Invest34122814764075
  • ChenJZhangPZuoP1997Memory-related changes of nitric oxide synthase activity and nitrite level in rat brainNeuroreport8177149189930
  • CorbalánRChatauretNBehrendsS2002Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patientsHepatology3611556212395325
  • CordobaJDupuisJGottsteinJ1997Stenosis of a portacaval anastomosis affects circadian locomotor activity in the rat:a multivariable analysisAm J Physiol273G1218259435546
  • CordobaJCabreraJLataifL1998High prevalence of sleep disturbance in cirrhosisHepatology27339459462628
  • DanyszWZajaczkowskiWParsonsCG1995Modulation of learning processes by ionotropic glutamate receptor ligandsBehav Pharmacol64557411224354
  • DelayER1996Effects of MK-801 on acquisition, retention and cross-modal transfer of active avoidance behaviour in ratsPsychobiology24195201
  • ElithornALunzerMWeinmanJ1975Cognitive deficit associated with chronic hepatic encephalopathy and their response to levodopaJ Neurol Neurosurg Psych387948
  • ErcegSMonfortPHernandez-ViadelM2005aOral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shuntsHepatology4129930615660436
  • ErcegSMonfortPHernandez-ViadelM2005bRestoration of learning ability in hyperammonemic rats by increasing extracellular cGMP in brainBrain Res10361152115725408
  • FelipoVButterworthRF2002Neurobiology of ammoniaProg Neurobiol672597912207972
  • FerenciPPappasSCMunsonPJ1984Changes in glutamate receptors on synaptic membranes associated with hepatic encephalopathy or hyperammonemia in the rabbitHepatology42596141134
  • FerenciPLockwoodAMullenK2002Hepatic encephalopathy–definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998Hepatology357162111870389
  • Garcia-MorenoLMConejoNMGonzalez-PardoH2005Evaluation of two experimental models of hepatic encephalopathy in ratsBraz J Med Biol Res381273215665999
  • GarfinkelDZisapelN1996Liver cirrhosis and circadian rhythmAnn Intern Med1251548678376
  • GasullTDeGregorio-RocasolanoNZapataA2000Choline release and inhibition of phosphatidylcholine synthesis precede excitotoxic neuronal death but not neurotoxicity induced by serum deprivationJ Biol Chem27518350710748226
  • GilberstadtSJGilberstadtHZieveL1980Psychomotor performance defects in cirrhotic patients without overt encephalopathyArch Intern Med140519217362383
  • GroenewegMQueroJCDe BruijnI1998Subclinical hepatic encephalopathy impairs daily functioningHepatology284599657095
  • HartmannIJGroenewegMQueroJC2000The prognostic significance of subclinical hepatic encephalopathyAm J Gastroenterol9520293410950053
  • HayashiTKatsumiYMukaiT2002Neuronal nitric oxide has a role as a perfusion regulator and a synaptic modulator in cerebellum but not in neocortex during somatosensory stimulation—an animal PET studyNeurosci Res441556512354630
  • HermenegildoCMontoliuCLlansolaM1998Chronic hyperammonemia impairs glutamatenitric oxide-cyclic GMP pathway in cerebellar neurons in culture and in the rat in vivoEur J Neurosci10320199786213
  • HuertaPTSunLDWilsonMA2000Formation of temporal memory requires NMDA receptors within CA1 pyramidal neuronsNeuron254738010719900
  • IguchiHKatoKIIbayashiH1982Melatonin serum levels and metabolic clearance rate in patients with liver cirrhosisJ Clin Endocrinol Metab54102577061695
  • IngramDKSpanglerELKametaniH1998Intraventricular injection of N-nitro-L-arginine in rats impairs learning in a 14-unit T- mazeEur J Pharmacol34111169489850
  • IngramDKSpanglerELMeyerRC1998bLearning in a 14-unit T-maze is impaired in rats following the systemic treatmentwith N-nitro-L-argininaEur J Pharmacol341199489849
  • LockwoodAHYapEWWongWH1991Cerebral ammonia metabolism in patients with severe liver disease and minimal hepatic encephalopathyJ Cereb Blood Flow Metab11337411997506
  • LopezLGonzalez-PardoHCimadevillaJM2002Cytochrome oxidase activity of the suprachiasmatic nucleus and pineal gland in rats with portacaval shuntExp Neurol1732758211822891
  • LozevaVValjakkaALecklinA2000Effects of the histamine H(1) receptor blocker, pyrilamine, on spontaneous locomotor activity of rats with long-term portacaval anastomosisHepatology313364410655255
  • LozevaVTuominenRKMannistoPT2002Effect of repeated L-histidine administration on plasma prolactin and growth hormone levels in ratsInflamm Res51S44512013404
  • McCreaMCordobaJVesseyG1996Neuropsychological characterization and detection of subclinical hepatic encephalopathyArch Neurol53758638759982
  • McHughTJBlumKITsienJZ1996Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout miceCell871339498980239
  • MarchesiniGBianchiGAmodioP2001Factors associated with poor health-related quality of life of patients with cirrhosisGastroenterology120170811208726
  • MartinJROettingerRBattigK1986Behavioral effects of experimental portacaval anastomosis measured in Dashiell and radial tunnel maze configurationsPhysiol Behav382143786498
  • MauriceTSuTPParishDWNabeshim1994PRE-084, a sigma selective PCP derivative, attenuates MK-801-induced impairment of learning in micePharmacol Biochem Behav49859697886099
  • MeyerRCKnoxJPurwinDA1998Combined stimulation of the glycine and polyamine sites of the NMDA receptor attenuates NMDA blockade-induced learning deficits of rats in a 14-unit-T-mazePsychopharmacology13529059498733
  • MonfortPCorbalánRMartínezL2001Altered content and modulation of soluble guanylate cyclase in the cerebellum of rats with portacaval anastomosisNeuroscience10411192511457595
  • MontoliuCLlansolaMKosenkoE1999Role of cyclic GMP in glutamate neurotoxicity in primary cultures of cerebellar neuronsNeuropharmacology3818839110608283
  • MoroniFLombardiGMonetiG1983The release and neosynthesis of glutamic acid are increased in experimental models of hepatic encephalopathyJ Neurochem4085046131108
  • MorrisRGHaganJJRawlinsJN1986Allocentric spatial learning by hippocampectomised rats:a further test of the “spatial mapping” and “working memory” theories of hippocampal functionQ J Exp Psychol B38365953809580
  • MyslivecekJ1997Inhibitory learning and memory in new-born ratsProg Neurobiol533994309421830
  • MurrayTKRidleyRM1997The effect of dizocilpine (MK-801) on conditional discrimination learning in the ratBehav Pharmacol838389832977
  • PackardMGTeacherLA1997Posttraining injections of MK-801 procedure a time- dependent impairment of memory in two water maze tasksNeurobiol Learn Mem6842509195588
  • PaolilloMFelicielloAPorcelliniA1999The type and the localization of cAMP-dependent protein kinase regulate transmission of cAMP signals to the nucleus in cortical and cerebellar granule cellsJ Biol Chem27465465210037748
  • Parada-TurskaJTurskiWA1990Excitatory amino acid antagonists and memory:effect of drugs acting at N-methyl-D-aspartate receptors in learning and memory tasksNeuropharmacology291111162149871
  • Parsons-SmithBGSummerskillWHJDawsonAM1957The electroencephalograph in liver diseaseLancet28677113482229
  • PatelNSpanglerELGreigNH1998Phenserine, a novel acetylcho-linesterase inhibitor, attenuates impaired learning of rats in a 14-unit T-maze induced by blockade of the N-methyl-D-aspartate receptorNeuroreport917169592071
  • PrickaertsJSteinbuschHWSmitsJF1997Possible role of nitric oxide –cyclic GMP pathway in object recognition memory:Effects of 7-nitroindazole and zaprinastEur J Pharmacol337125369430406
  • PrickaertsJDe venteJOngW2002cGMP, but not cAMP, in rat hippocampus is involved in early stages of object memory consolidationEur J Pharmacol43683711834250
  • RamponCTsienJZ2000Genetic analysis of learning behaviour-induced structural plasticityHippocampus10605911075831
  • RedolatRCarrascoMCSimonVM1998Efectos de la administración aguda de MK-801, antagonista no competitivo de los receptores NMDA, sobre la evitación activa en ratonesPsicothema1013541
  • RehnstromSSimertGHanssonJA1977Chronic hepatic encephalopathy A psychometrical studyScand J Gastroenterol1230511866992
  • RiekkinenMStefanskiRKuitunenJ1996Effects of combined block of alpha 1-adrenoceptors and NMDA receptors on spatial and passive avoidance behaviour in ratsEur J Pharmacol3009168741159
  • RikkersLJenkoPRudmanDFreidesD1978Subclinical hepatic encephalopathy:detection, prevalence, and relationship to nitrogen metabolismGastroenterology754629680502
  • RodrigoRJoverRCandelaA2005Bile duct ligation plus hyper-ammonemia in rats reproduces the alterations in the modulation of soluble guanylate cyclase by nitric oxide in brain of cirrhotic patientsNeuroscience1304354315664700
  • Romero-GomezMBozaFGarcia-ValdecasasMS2001Subclinical hepatic encephalopathy predicts the development of overt hepatic encephalopathyAm J Gastroenterol9627182311569701
  • SakimuraKKutsuwadaTItoIManabe1995Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunitNature37315157816096
  • SasakiSSiragyHMGildeaJJ2004production and role of extracellular guanosine cyclic 3',5' monophosphate in sodium uptake in human proximal tubule cellsHypertension432869114718358
  • SchomerusHHamsterW1998Neuropsychological aspects of portal-systemic encephalopathyMetab Brain Dis133617710206827
  • SchomerusHHamsterW2001Quality of life in cirrhotics with minimal hepatic encephalopathyMetab Brain Dis16374111726087
  • SchomerusHHamsterWBlunckH1981Latent portasystemic encephalopathy. I. Nature of cerebral functional defects and their effect on fitness to driveDig Dis Sci26622307249898
  • SmithRDGrzelakMECoffinVL1997Reduction of dizocilpine and scopolamine-induced deficits in avoidance responding by SCH 54388, a metabolite of felbamatePharmacol Biochem Behav58657649329055
  • SmithSDringenbergHCBennettBM2000A novel nitrate ester reverses the cognitive impairment caused by scopolamine in the Morris water mazeNeuroreport113883611117508
  • SrivastavaAMehtaRRothkeSP1994Fitness to drive in patients with cirrhosis and portal-systemic shunting:a pilot study evaluating driving performanceJ Hepatol21102387699223
  • SteindlPEFinnBBendokB1995Disruption of the diurnal rhythm of plasma melatonin in cirrhosisAnn Intern Med12327477611593
  • SteindlPECoyDLFinnB1996A low-protein diet ameliorates disrupted diurnal locomotor activity in rats after portacaval anastomosisAm J Physiol271G555608897872
  • TangYPShimizuEDubeGRRampon1999Genetic enhancement of learning and memory in miceNature40163910485705
  • TarterREHegedusAMVan ThielDH1984Nonalcoholic cirrhosis associated with neuropsychological dysfunction in the absence of overt evidence of hepatic encephalopathyGastroenterology86142176714571
  • TarterREArriaAMCarraJ1987Memory impairments concomitant with nonalcoholic cirrhosisInt J Neurosci3285393596928
  • ThiessonHCJensenBLJespersenB2005Inhibition of cGMP-specific phosphodiesterase type 5 reduces sodium excretion and arterial blood pressure in patients with NaCl retention and ascitesAm J Physiol288F104452
  • TsienJZHuertaPTTonegawaS1996The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memoryCell871327388980238
  • TzathasCChristidouALadasSD2002Sildenafil (viagra) is a risk factor for acute variceal bleedingAm J Gastroenterol97185612135063
  • Van der RijtCCSchalmSW1992Quantitative EEG analysis and evoked potentials to measure (latent) hepatic encephalopathyJ Hepatol1414121500675
  • WangVSaabS2003Ammonia levels and the severity of hepatic encephalopathyAm J Med114237812637141
  • WeissenbornKHeidenreichSEnnenJ2001Attention deficits in minimal hepatic encephalopathyMetab Brain Dis16131911726083
  • WeissenbornKHeidenreichSGiewekemeyerK2003Memory function in early hepatic encephalopathyJ Hepatol39320512927916
  • XuX1997NMDA receptor antagonist MK-801 selectively impairs learning of the contiguity of the conditioned stimulus and unconditioned stimulus in goldfishPharmacol Biochem Behav5849169300610
  • YamadaKHiramatsuMNodaY1996Role of nitric oxide and cyclic GMP in the dizocilpine-induced impairment of spontaneous alternation behavior in miceNeuroscience74365748865189
  • ZeePCMehtaRTurekFW1991Portacaval anastomosis disrupts circadian locomotor activity and pineal melatonin rhythms in ratsBrain Res56017221760725
  • ZouL-BYamadaKTanakaT1998Nitric oxide synthase inhibitors impair reference memory formation in a radial arm maze task in ratsNeuropharmacology37323309681930

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