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Expert Opinion

Levetiracetam in the treatment of childhood epilepsy

Pages 409-421 | Published online: 25 Nov 2022

References

  • AebyAPoznanskiNVerheulpenD2005Levetiracetam efficacy in epileptic syndromes with continuous spikes and waves during slow sleep: experience in 12 casesEpilepsia4619374216393159
  • AndermannEAndermannFMeyvischP2005Seizure control with levetiracetam in juvenile myoclonic epilepsiesEpilepsia46Suppl 8205
  • BioSpace Beat2007Keppra approved for US epilepsy patients with one of the most debilitating seizure types [online]Accessed 25 April 2007 URL: http://www.biospace.com/news_story.aspx?StoryID=49789&full=1
  • BitonV2003Effect of antiepileptic drugs on bodyweight: overview and clinical implications for the treatment of epilepsyCNS Drugs177819112921491
  • BriggsDEFrenchJA2004Levetiracetam safety profiles and tolerability in epilepsy patientsExpert Opin Drug Saf34152415335297
  • BrodieMJPeruccaERyvlinP2007Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsyNeurology68402817283312
  • CollinsJJTudorCLeonardJM2006Levetiracetam as adjunctive antiepileptic therapy for patients with tuberous sclerosis complex: a retrospective open-label trialJ Child Neurol2153716551454
  • CoppolaGManganoSTortorellaG2004Levetiracetam during 1-year follow-up in children, adolescents, and young adults with refractory epilepsyEpilepsy Res59354215135165
  • CoupezRStraetemansRSehgalG2003Levetiracetam: relative bioavailability and bioequivalence of a 10% oral solution (750 mg) and 750-mg tabletsJ Clin Pharmacol431370614615473
  • FrenchJEdrichPCramerJA2001A systematic review of the safety profile of levetiracetam: a new antiepileptic drugEpilepsy Res47779011673023
  • FrenchJAKannerAMBautistaJ2004Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy SocietyNeurology6212617315111660
  • GidalBEShethRDMagnusL2003Levetiracetam does not alter body weight: analysis of randomized, controlled clinical trialsEpilepsy Res56121614642996
  • GlauserTAAyalaREltermanRD2006Double-blind placebo-controlled trial of adjunctive levetiracetam in pediatric partial seizuresNeurology6616546016641323
  • GlauserTAPellockJMBebinEM2002Efficacy and safety of levetiracetam in children with partial seizures: an open-label trialEpilepsia435182412027913
  • GrossoSFranzoniECoppolaG2005Efficacy and safety of levetiracetam: an add-on trial in children with refractory epilepsySeizure142485315911359
  • HerranzJLRufo-CamposMArteagaR2003[Effectiveness and tolerability of levetiracetam in 43 children and adolescents with epilepsy]. SpanishRev Neurol371005814669138
  • Keppra [package insert]Smyrna, GaUCB Pharma, Inc2004
  • KlitgaardH2001Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?Epilepsia42Suppl 413811564119
  • KraussGLBettsTAbou-KhalilB2003Levetiracetam treatment of idiopathic generalised epilepsySeizure126172014630506
  • KumarSPSmithPE2004Levetiracetam as add-on therapy in generalised epilepsiesSeizure13475715324824
  • LagaeLBuyseGCeulemansB2005Clinical experience with levetiracetam in childhood epilepsy: an add-on and mono-therapy trialSeizure14667115642504
  • LagaeLBuyseGDeconinckA2003Effect of levetiracetam in refractory childhood epilepsy syndromesEur J Paediatr Neurol7123812788038
  • LambertyYMargineanuDGKlitgaardH2000Absence of negative impact of levetiracetam on cognitive function and memory in normal and amygdala-kindled ratsEpilepsy Behav13334212609164
  • LeppikIE2001Issues in the treatment of epilepsyEpilepsia42Suppl 41611564117
  • LevyRHRagueneau-MajlessiIBaltesE2001Repeated administration of the novel antiepileptic agent levetiracetam does not alter digoxin pharmacokinetics and pharmacodynamics in healthy volunteersEpilepsy Res4693911463510
  • LukyanetzEAShkrylVMKostyukPG2002Selective blockade of N-type calcium channels by levetiracetamEpilepsia4391811879381
  • LynchBALambengNNockaK2004The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetamProc Natl Acad Sci USA1019861615210974
  • MandelbaumDEBunchMKuglerSL2005Efficacy of levetiracetam at 12 months in children classified by seizure type, cognitive status, and previous anticonvulsant drug useJ Child Neurol20590416159526
  • MantheyDAsimiadouSStefovskaV2005Sulthiame but not levetiracetam exerts neurotoxic effect in the developing rat brainExp Neurol19349750315869952
  • MeadorKJLoringDWRayPG2006Cognitive and behavioral effects of carbamazepine and levetiracetam in healthy volunteersNeurology66Suppl 2A.73
  • MecarelliOVicenziniEPulitanoP2004Clinical, cognitive, and neurophysiologic correlates of short-term treatment with carbamazepine, oxcarbazepine, and levetiracetam in healthy volunteersAnn Pharmacother3818162215367726
  • Medical News Today2005FDA approves UCB’s Keppra® for use in childhood epilepsy [online]Accessed 30 March 2006 URL: http://www.medicalnewstoday.com/medicalnews.php?newsid=26559
  • Medical News Today2006UCB receives EMEA positive opinion and FDA approvable letter for Keppra® (levetiracetam) intravenous administration [online]Accessed 30 March 2006 URL: http://www.medicalnewstoday.com/printerfriendlynews.php?newsid=37150
  • Ness-AbramofRApovianCM2005Drug-induced weight gainDrugs Today (Barc)415475516234878
  • OppJTuxhornIMayT2005Levetiracetam in children with refractory epilepsy: a multicenter open label study in GermanySeizure144768416182573
  • OttDSiddarthPGurbaniS2003Behavioral disorders in pediatric epilepsy: unmet psychiatric needEpilepsia44591712681010
  • Paola CaneviniMChifariRPiazziniA2002Improvement of a patient with stuttering on levetiracetamNeurology59128812391373
  • PatsalosPN2000Pharmacokinetic profile of levetiracetam: toward ideal characteristicsPharmacol Ther85778510722121
  • PatsalosPN2003The pharmacokinetic characteristics of levetiracetamMethods Find Exp Clin Pharmacol25123912731458
  • PellockJM1999Managing pediatric epilepsy syndromes with new anti-epileptic drugsPediatrics10411061610545555
  • PellockJMGlauserTABebinEM2001Pharmacokinetic study of levetiracetam in childrenEpilepsia421574911879369
  • PeruccaE2006Clinically relevant drug interactions with antiepileptic drugsBr J Clin Pharmacol612465516487217
  • PeruccaEGidalBEBaltesE2003Effects of antiepileptic comedication on levetiracetam pharmacokinetics: a pooled analysis of data from randomized adjunctive therapy trialsEpilepsy Res53475612576167
  • PiazziniAChifariRCaneviniMP2006Levetiracetam: an improvement of attention and of oral fluency in patients with partial epilepsyEpilepsy Res68181816332430
  • Ragueneau-MajlessiILevyRHJanikF2002Levetiracetam does not alter the pharmacokinetics of an oral contraceptive in healthy womenEpilepsia4369770212102671
  • Ragueneau-MajlessiILevyRHMeyerhoffC2001Lack of effect of repeated administration of levetiracetam on the pharmacodynamic and pharmacokinetic profiles of warfarinEpilepsy Res47556311673021
  • RamaelSDe SmedtFToublancN2006Single-dose bioavailability of levetiracetam intravenous infusion relative to oral tablets and multiple-dose pharmacokinetics and tolerability of levetiracetam intravenous infusion compared with placebo in healthy subjectsClin Ther287344416861095
  • RigoJMHansGNguyenL2002The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currentsBr J Pharmacol1366597212086975
  • RosenfeldWBerkovicSKnowltonR2006Efficacy and safety of levetiracetam as adjunctive treatment in adult and paediatric patients suffering from idiopathic generalized epilepsy with primary generalized tonic-clonic seizuresNeurology66Suppl 2A40
  • ShannonHELovePL2004Effects of antiepileptic drugs on working memory as assessed by spatial alternation performance in ratsEpilepsy Behav58576515582833
  • ShannonHELovePL2005Effects of antiepileptic drugs on attention as assessed by a five-choice serial reaction time task in ratsEpilepsy Behav7620816253568
  • ShinnarSPellockJM2002Update on the epidemiology and prognosis of pediatric epilepsyJ Child Neurol17Suppl 1S41711918462
  • ShoafTLLuZYeeKF2005Evaluation of the relative risk of psychiatric and behavioral adverse events in pediatric patients with refractory partial seizures treated with levetiracetam—impact of prior history and a comparison with adult dataEpilepsia46Suppl 82045
  • ShorvonS2000General principles of treatment in epilepsyHandbook of epilepsy treatmentOxford, EnglandBlackwell Science Ltd3483
  • TanMJAppletonRE2004Efficacy and tolerability of levetiracetam in children aged 10 years and younger: a clinical experienceSeizure13142515010050
  • TongXPatsalosPN2001A microdialysis study of the novel antiepileptic drug levetiracetam: extracellular pharmacokinetics and effect on taurine in rat brainBr J Pharmacol1338677411454660
  • VerdruP2005Epilepsy in children: the evidence for new antiepileptic drugsActa Neurol Scand Suppl181172016238703
  • VerloesRScottoAGobertJ1988Effects of nootropic drugs in a scopalamine-induced amnesia model in micePsychopharmacology95226303137602
  • WhelessJWClarkeDFCarpenterD2005Treatment of pediatric epilepsy: Expert opinion, 2005J Child Neurol20Suppl 1S15616615562
  • WhelessJWNgYT2002Levetiracetam in refractory pediatric epilepsyJ Child Neurol17413512174960

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