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Expert Opinion

Emerging treatments for premature ejaculation: focus on dapoxetine

Pages 37-46 | Published online: 21 Dec 2008

References

  • AlthofSEPrevalence, characteristics and implications of premature ejaculation/rapid ejaculationJ Urol2006175(3 Pt 1)84284816469562
  • PorstHMontorsiFRosenRCGaynorLGrupeSAlexanderJThe Premature Ejaculation Prevalence and Attitudes (PEPA) survey: prevalence, comorbidities, and professional help-seekingEur Urol200751381682416934919
  • CarsonCGunnKPremature ejaculation: definition and prevalenceInt J Impot Res200618suppl 1S5S1316953247
  • WaldingerMDRecent advances in the classification, neurobiology and treatment of premature ejaculationAdv Psychosom Med200829506918391557
  • American Psychiatric AssociationDiagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text RevisionWashington, DCAmerican Psychiatric Association2000
  • McMahonCGAlthofSEWaldingerMDAn evidence-based definition of lifelong premature ejaculation: report of the International Society for Sexual Medicine (ISSM) Ad Hoc Committee for the Definition of Premature EjaculationJ Sex Med2008571590160618466262
  • DunnKMCroftPRHackettGIAssociation of sexual problems with social, psychological, and physical problems in men and women: a cross sectional population surveyJ Epidemiol Community Health199953314414810396490
  • RowlandDPerelmanMAlthofSSelf-reported premature ejaculation and aspects of sexual functioning and satisfactionJ Sex Med20041222523216429622
  • SotomayorMThe burden of premature ejaculation: the patient perspectiveJ Sex Med20052suppl 211010416422797
  • RowlandDLPatrickDLRothmanMGagnonDDThe psychological burden of premature ejaculationJ Urol200717731065107017296413
  • PatrickDLAlthofSEPryorJLPremature ejaculation: an observational study of men and their partnersJ Sex Med20052335836716422867
  • GiulianoFPatrickDLPorstHPremature ejaculation: results from a five-country European observational studyEur Urol20085351048105717950985
  • PorstHGiulianoFPatrickDLImpact of premature ejaculation (PE) on female partners: results from a 5-country European observational study [abstract]Eur Urol Suppl200873186
  • CarsonCCGlasserDBLaumannEOWestSLRosenRCPrevalence and correlates of premature ejaculation among men aged 40 years and older: a United States nationwide population-based study [abstract]J Urol20031694 suppl321322
  • MoreiraEDJrBrockGGlasserDBHelp-seeking behaviour for sexual problems: the Global Study of Sexual Attitudes and BehaviorsInt J Clin Pract200559161615707457
  • GiulianoF5-hydroxytryptamine in premature ejaculation: opportunities for therapeutic interventionTrends Neurosci2006302798417169440
  • WoltersJPHellstromWJCurrent concepts in ejaculatory dysfunctionRev Urol20068suppl 4S18S2517215997
  • GiulianoFHellstromWJGThe pharmacological treatment of premature ejaculationBJU Int2008102666867518485043
  • BarnesTEardleyIPremature ejaculation: the scope of the problemJ Sex Marital Ther200733215117017365515
  • McMahonCThe etiology and management of premature ejaculationNat Clin Pract Urol20052942643316474680
  • MastersWJohnsonVHuman Sexual InadequacyBoston, MALittle Brown and Co1970
  • SemansJPremature ejaculation: a new approachS Med J195649353358
  • De AmicisLAGoldbergDCLoPiccoloJFriedmanJDaviesLClinical follow-up of couples treated for sexual dysfunctionArch Sex Behav1985146467894084048
  • HawtonKCatalanJMartinPFaggJLong-term outcome of sex therapyBehav Res Ther19862466656753800838
  • McCabeMPEvaluation of a cognitive behavior therapy program for people with sexual dysfunctionJ Sex Marital Ther200127325927111354931
  • Abdel-HamidIAEl NaggarEAEl GilanyA-HAssessment of as needed use of pharmacotherapy and the pause-squeeze technique in premature ejaculationInt J Impot Res2001131414511313839
  • MoralesABaradaJWyllieMGA review of the current status of topical treatments for premature ejaculationBJU Int2007100349350117608824
  • AtikelerMKGecitISenolFAOptimum usage of prilocaine-lidocaine cream in premature ejaculationAndrologia200234635635912472618
  • BusatoWGalindoCCTopical anaesthetic use for treating premature ejaculation: a double-blind, randomized, placebo-controlled studyBJU Int20049371018102115142155
  • HenryRMoralesATopical lidocaine-prilocaine spray for the treatment of premature ejaculation: a proof of concept studyInt J Impot Res200315427728112934056
  • DinsmoreWWHackettGGoldmeierDTopical eutectic mixture for premature ejaculation (TEMPE): a novel aerosol-delivery form of lidocaine-prilocaine for treating premature ejaculationBJU Int200699236937517129234
  • ChoiHKXinZCChoiYDLeeWHMahSYKimDKSafety and efficacy study with various doses of SS-cream in patients with premature ejaculation in a double-blind, randomized, placebo controlled clinical studyInt J Impot Res199911526126410553804
  • ChoiHKJungGWMoonKHClinical study of SS-cream in patients with lifelong premature ejaculationUrology200055225726110688090
  • Montejo-GonzálezALLlorcaGIzquierdoJASSRI-induced sexual dysfunction: fluoxetine, paroxetine, sertraline, and fluvoxamine in a prospective, multicenter, and descriptive clinical study of 344 patientsJ Sex Marital Ther19972331761949292833
  • MontejoALLlorcaGIzquierdoJARico-VillademorosFIncidence of sexual dysfunction associated with antidepressant agents: a prospective multicenter study of 1022 outpatients. Spanish Working Group for the Study of Psychotropic-Related Sexual DysfunctionJ Clin Psychiatry200162suppl 3102111229449
  • ChouinardGSaxenaBBélangerM-CA Canadian multicenter, double-blind study of paroxetine and fluoxetine in major depressive disorderJ Affect Disord1999541–2394810403145
  • WaldingerMDHengeveldMWZwindermanAHOlivierBEffect of SSRI antidepressants on ejaculation: a double-blind, randomized, placebo-controlled study with fluoxetine, fluvoxamine, paroxetine, and sertralineJ Clin Psychopharmacol19981842742819690692
  • WaldingerMDHengeveldMWZwindermanAHParoxetine treatment of premature ejaculation: a double-blind, randomized, placebo-controlled studyAm J Psychiatry19941519137713798067497
  • AtmacaMKulogluMTezcanESemerciozAThe efficacy of citalopram in the treatment of premature ejaculation: a placebo-controlled studyInt J Impot Res200214650250512494286
  • McMahonCGToumaKTreatment of premature ejaculation with paroxetine hydrochloride as needed: 2 single-blind placebo controlled crossover studiesJ Urol199916161826183010332446
  • OpbroekADelgadoPLLaukesCEmotional blunting associated with SSRI-induced sexual dysfunction. Do SSRIs inhibit emotional responses?Int J Neuropsychopharmacol20025214715112135539
  • BlackKSheaCDursunSKutcherSSelective serotonin reuptake inhibitor discontinuation syndrome: proposed diagnostic criteriaJ Psychiatry Neurosci200025325526110863885
  • ChenJKeren-PazGBar-YosefYMatzkinHThe role of phosphodiesterase type 5 inhibitors in the management of premature ejaculation: a critical analysis of basic science and clinical dataEur Urol20075251331133917728050
  • MondainiNPonchiettiRMuirGHSildenafil does not improve sexual function in men without erectile dysfunction but does reduce the postorgasmic refractory timeInt J Impot Res200315322522812904810
  • McMahonCGMcMahonCNLeowLJWinestockCGEfficacy of type-5 phosphodiesterase inhibitors in the drug treatment of premature ejaculation: a systematic reviewBJU Int200698225927216879663
  • McMahonCGStuckeyBGAndersenMEfficacy of sildenafil citrate (Viagra) in men with premature ejaculationJ Sex Med20052336837516422868
  • SaloniaAMagaTColomboRA prospective study comparing paroxetine alone versus paroxetine plus sildenafil in patients with premature ejaculationJ Urol200216862486248912441946
  • HosseiniMMYarmohammadiHEffect of fluoxetine alone and in combination with sildenafil in patients with premature ejaculationUrol Int2007791283217627164
  • MattosRMMarmo LuconASrougiMTadalafil and fluoxetine in premature ejaculation: prospective, randomized, double-blind, placebo-controlled studyUrol Int200880216216518362486
  • MalavigeLSJayaratneSDKathriarachchiSTSivayoganSFernandoDJLevyJCErectile dysfunction among men with diabetes is strongly associated with premature ejaculation and reduced libidoJ Sex Med2008592125213418624974
  • SalemEAWilsonSKBissadaNKDelkJRHellstromWJClevesMATramadol HCL has promise in on-demand use to treat premature ejaculationJ Sex Med20085118819317362279
  • SafarinejadMRHosseiniSYSafety and efficacy of tramadol in the treatment of premature ejaculation: a double-blind, placebo-controlled, fixed-dose, randomized studyJ Clin Psychopharmacol2006261273116415702
  • ClémentPBernabéJGengoPSupraspinal site of action for the inhibition of ejaculatory reflex by dapoxetineEur Urol200751382583217064843
  • GiulianoFBernabeJGengoPAlexandreLClementPEffect of acute dapoxetine administration on the pudendal motoneuron reflex in anesthetized rats: comparison with paroxetineJ Urol2007177138638917162096
  • GengoPJGiulianoFMcKennaKMonoaminergic transporter binding and inhibition profile of dapoxetine, a medication for the treatment of premature ejaculation [abstract]J Urol2005173423915592087
  • HiemkeCHartterSPharmacokinetics of selective serotonin reuptake inhibitorsPharmacol Ther2000851112810674711
  • ModiNBDresserMJSimonMLinDDesaiDGuptaSSingle- and multiple-dose pharmacokinetics of dapoxetine hydrochloride, a novel agent for the treatment of premature ejaculationJ Clin Pharmacol200646330130916490806
  • KendirciMSalemEHellstromWJDapoxetine, a novel selective serotonin transport inhibitor for the treatment of premature ejaculationTher Clin Risk Manag20073227728918360636
  • PAXIL® (paroxetine hydrochloride) Tablets and Oral Suspension [package insert]Research Triangle Park, NCGlaxoSmithKline2007
  • ZOLOFT® (sertraline hydrochloride) Tablets and Oral Concentrate [package insert]New York, NYPfizer Inc2005
  • PryorJLAlthofSESteidleCEfficacy and tolerability of dapoxetine in treatment of premature ejaculation: an integrated analysis of two double-blind, randomised-controlled trialsLancet2006368953992993716962882
  • McMahonCParkNCZhaoYRothmanMRivasDTreatment of premature ejaculation (PE) in the Asia-Pacific region: results from a phase III double-blind, parallel-group study of dapoxetineOral presentation at: 11th Biennial Meeting of the Asia Pacific Society for Sexual Medicine; October 6–10, 2007; Jeju, Korea. Abstract OS05_06.
  • BuvatJGiulianoFTesfayeFRothmanMRivasDEfficacy and safety of dapoxetine for premature ejaculation (PE): results from a placebo-controlled, double-blind, randomized, parallel-group study in 22 countries [abstract]Urology200770315
  • KaufmanJMRosenRCMudumbiRVTesfayeFHashmonayRRivasDTreatment benefit of dapoxetine for premature ejaculation: results from a placebo-controlled phase III trial [published online ahead of print November 19, 2008]BJU Intdoi:10.1111/j.1464-410X.2008.08165.x.
  • PatrickDLGiulianoFHoKFGagnonDDMcNultyPRothmanMThe Premature Ejaculation Profile (PEP): validation of self-reported outcome measures for research and practice [published online ahead of print September 12, 2008]BJU Intdoi:10.1111/j.1464-410X.2008.08041.x.
  • BuvatJGiulianoFTesfayeFRothmanMRivasDPatient-reported treatment benefit of dapoxetine (DPX) for the treatment of premature ejaculation (PE) in 22 countries [abstract]J Sex Med20085suppl 130
  • BrockGBuvatJGiulianoFImprovement in sexual satisfaction of female partners of men with premature ejaculation (PE) treated with dapoxetine (DPX) [abstract]J Urol2008179suppl 443143218076919
  • BuvatJGiulianoFTesfayeFRothmanMRivasDImprovement in sexual functioning of female partners of men with premature ejaculation (PE) treated with dapoxetine (DPX) [abstract]Eur Urol Suppl200873186
  • ParkNCMcMahonCTesfayeFZhaoYRothmanMRivasDSafety and tolerability of dapoxetine for the treatment of premature ejaculation in an Asia-Pacific populationOral presentation at: 11th Biennial Meeting of the Asia Pacific Society for Sexual Medicine; October 6–10, 2007; Jeju, Korea. Abstract OS05_07.
  • ShabsighRPryorJLTesfayeFDapoxetine for the treatment of premature ejaculation: low incidence of sexual side effects. In: Chen J, Arver S (chairpersons). P-05 Ejaculatory DisordersJ Sex Med20074suppl 2118
  • CaseyRTesfayeFMudumbiRRothmanMRivasDEffects of dapoxetine (DPX) for the treatment of premature ejaculation (PE) on the erectile function and scales of mood and affect [abstract]Eur Urol Suppl200873186
  • GiulianoFLevineSBBuvatJLack of withdrawal syndrome or effects on anxiety with dapoxetine (DPX) for the treatment of premature ejaculation (PE): results from 2 phase III trials [abstract]Eur Urol Suppl200873187

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