References
- OstlingSSkoogIPsychotic symptoms and paranoid ideation in a nondemented population-based sample of the very oldArch Gen Psychiatry2002591535911779282
- JesteDVJLWCRDSchizophrenia and paranoid disordersBlazerDGSDBusseEWTextbook of Geriatric Psychiatry3rd edWashington, DCAmerian Psychiatric Publishing, Inc2004269281
- CummingsJLFBDDementia: A clinical approach2nd edBostonButterworth-Heinemann1992
- JesteDVFinkelSIPsychosis of Alzheimer’s disease and related dementias. Diagnostic criteria for a distinct syndromeAm J Geriatr Psychiatry200081293410648292
- BurnsAJacobyRLevyRPsychiatric phenomena in Alzheimer’s disease. IV: Disorders of behaviourBr J Psychiatry199015786942397368
- FreedmanRSchizophreniaN Engl J Med2003349181738174914585943
- WorrelJAMarkenPABeckmanSERuehterVLAtypical antipsychotic agents: a critical reviewAm J Health Syst Pharm200057323825510674777
- CastleDJMurrayRMThe epidemiology of late-onset schizophreniaSchizophr Bull19931946917008303220
- HowardRRabinsPVSeemanMVJesteDVLate-onset schizophrenia and very-late-onset schizophrenia-like psychosis: an international consensus. The International Late-Onset Schizophrenia GroupAm J Psychiatry2000157217217810671383
- HowardRJGrahamCShamPA controlled family study of late-onset non-affective psychosis (late paraphrenia)Br J Psychiatry19971705115149330015
- CopelandJRDeweyMEScottASchizophrenia and delusional disorder in older age: community prevalence, incidence, comorbidity, and outcomeSchizophr Bull19982411531619502553
- KeithSJReigerDARaeDSSchizophrenic disorders in America: the epidemiologic catchment area studyNew YorkFree Press1991
- HuberGThe heterogeneous course of schizophreniaSchizophr Res19972823177185
- BelitskyRMcGlashanTHThe manifestations of schizophrenia in late life: a dearth of dataSchizophr Bull19931946836858303218
- RamRBrometEJEatonWWPatoCSchwartzJEThe natural course of schizophrenia: a review of first-admission studiesSchizophr Bull19921821852071621068
- DavidsonMHarveyPDPowchikPSeverity of symptoms in chronically institutionalized geriatric schizophrenic patientsAm J Psychiatry199515221972077840352
- HeatonRKGladsjoJAPalmerBWKuckJMarcotteTDJesteDVStability and course of neuropsychological deficits in schizophreniaArch Gen Psychiatry2001581243211146755
- PalmerBWMcClureFSJesteDVSchizophrenia in late life: findings challenge traditional conceptsHarv Rev Psychiatry200192515811266402
- MadhusoodananSShahPManagement of psychosis in patients with Alzheimer’s disease: focus on aripiprazoleClin Interv Aging20083349150118982919
- PaulsenJSSalmonDPThalLJIncidence of and risk factors for hallucinations and delusions in patients with probable ADNeurology200054101965197110822438
- RopackiSAJesteDVEpidemiology of and risk factors for psychosis of Alzheimer’s disease: a review of 55 studies published from 1990 to 2003Am J Psychiatry2005162112022203016263838
- LopezOLWisniewskiSRBeckerJTBollerFDeKoskySTPsychiatric medication and abnormal behavior as predictors of progression in probable Alzheimer diseaseArch Neurol199956101266127210520944
- BriesacherBALimcangcoMRSimoni-WastilaLThe quality of antipsychotic drug prescribing in nursing homesArch Intern Med2005165111280128515956008
- DewaCSRemingtonGHerrmannNFearnleyJGoeringPHow much are atypical antipsychotic agents being used, and do they reach the populations who need them? A Canadian experienceClin Ther20022491466147612380638
- AlexopoulosGSJSCarpenterDThe expert consensus guideline series: using antipsychotics in older patientsJ Clin Psychiatry200465Suppl 2
- WooltortonERisperidone (Risperdal): increased rate of cerebrovascular events in dementia trialsCMAJ2002167111269127012451085
- WooltortonEOlanzapine (Zyprexa): increased incidence of cerebrovascular events in dementia trialsCMAJ20041709139515111472
- Administration. FaD. FDA public health advisory: deaths with antipsychotics in elderly patients with behavioral disturbances. http://www.fda.gov/cder/drug/advisory/antipsychotics.htm Accessed November 3, 2005.
- MadhusoodananSShahPBrennerRGuptaSPharmacological treatment of the psychosis of Alzheimer’s disease: what is the best approach?CNS Drugs200721210111517284093
- SajatovicMCoconceaNIgnacioRVAripiprazole therapy in 20 older adults with bipolar disorder: a 12-week, open-label trialJ Clin Psychiatry2008691414618312036
- HirschfeldRMCalabreseJRWeissmanMMScreening for bipolar disorder in the communityJ Clin Psychiatry2003641535912590624
- GildengersAGMulsantBHBegleyAEA pilot study of standardized treatment in geriatric bipolar disorderAm J Geriatr Psychiatry200513431932315845758
- FriedmanJHFactorSAAtypical antipsychotics in the treatment of drug-induced psychosis in Parkinson’s diseaseMov Disord200015220121110752567
- Low-dose clozapine for the treatment of drug-induced psychosis in Parkinson’s disease. The Parkinson Study GroupN Engl J Med19993401075776310072410
- BruceMLTen HaveTRReynoldsCF3rdReducing suicidal ideation and depressive symptoms in depressed older primary care patients: a randomized controlled trialJAMA200429191081109114996777
- UnutzerJKatonWCallahanCMCollaborative care management of late-life depression in the primary care setting: a randomized controlled trialJAMA2002288222836284512472325
- PapakostasGISheltonRCSmithJFavaMAugmentation of anti-depressants with atypical antipsychotic medications for treatment-resistant major depressive disorder: a meta-analysisJ Clin Psychiatry200768682683117592905
- BermanRMMarcusRNSwaninkRThe efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: a multicenter, randomized, double-blind, placebo-controlled studyJ Clin Psychiatry200768684385317592907
- BurrisKDMolskiTFXuCAripiprazole, a novel antipsychotic, is a high-affinity partial agonist at human dopamine D2 receptorsJ Pharmacol Exp Ther2002302138138912065741
- DeLeonAPatelNCCrismonMLAripiprazole: a comprehensive review of its pharmacology, clinical efficacy, and tolerabilityClin Ther200426564966615220010
- Ltd OPCProduct information: ABILIFY(R) oral tablets, oral solution, IM injection, ABILIFY DISCMELT(R) orally disintegrating tables, aripiprazole oral tablets, oral solution, IM injection, orally disintegrating tabletsTokyo, Japan; 2009
- BoultonDWKolliaGMallikaarjunSPharmacokinetics and tolerability of intramuscular, oral and intravenous aripiprazole in healthy subjects and in patients with schizophreniaClin Pharmacokinet200847747548518563956
- WaadeRBChristensenHRudbergIRefsumHHermannMInfluence of comedication on serum concentrations of aripiprazole and dehydroaripiprazoleTher Drug Monit200931223323819142178
- CitromeLMacherJPSalazarDEMallikaarjunSBoultonDWPharmacokinetics of aripiprazole and concomitant carbamazepineJ Clin Psychopharmacol200727327928317502775
- MallikaarjunSShoafSEBoultonDWBramerSLEffects of hepatic or renal impairment on the pharmacokinetics of aripiprazoleClin Pharmacokinet200847853354218611062
- ColeyKCScipioTMRubyCLenzeEJFabianTJAripiprazole prescribing patterns and side effects in elderly psychiatric inpatientsJ Psychiatr Pract200915215015319339850
- KaySRFiszbeinAOplerLAThe positive and negative syndrome scale (PANSS) for schizophreniaSchizophr Bull19871322612763616518
- MortimerAMSymptom rating scales and outcome in schizophreniaBr J Psychiatry Suppl200750s7s1418019038
- KaneJMCarsonWHSahaAREfficacy and safety of aripiprazole and haloperidol versus placebo in patients with schizophrenia and schizoaffective disorderJ Clin Psychiatry200263976377112363115
- McEvoyJPDanielDGCarsonWHJrMcQuadeRDMarcusRNA randomized, double-blind, placebo-controlled, study of the efficacy and safety of aripiprazole 10, 15 or 20 mg/day for the treatment of patients with acute exacerbations of schizophreniaJ Psychiatr Res2007411189590517631314
- PotkinSGSahaARKujawaMJAripiprazole, an antipsychotic with a novel mechanism of action, and risperidone vs placebo in patients with schizophrenia and schizoaffective disorderArch Gen Psychiatry200360768169012860772
- CutlerAJMarcusRNHardySAO’DonnellACarsonWHMcQuadeRDThe efficacy and safety of lower doses of aripiprazole for the treatment of patients with acute exacerbation of schizophreniaCNS Spectr2006119691702 quiz 719.16946694
- PigottTACarsonWHSahaARTorbeynsAFStockEGIngenitoGGAripiprazole for the prevention of relapse in stabilized patients with chronic schizophrenia: a placebo-controlled 26-week studyJ Clin Psychiatry20036491048105614628980
- [package insert] Ap. Otsuka America Pharmaceutical, Inc., Rockville MD and Bristol-Myers Squibb Co., Princeton NJ; November 2002.
- MadhusoodananSBrennerRGuptaSReddyHBogunovicOClinical experience with aripiprazole treatment in ten elderly patients with schizophrenia or schizoaffective disorder: retrospective case studiesCNS Spectr200491186286715520608
- De DeynPJesteDVSwaninkRAripiprazole for the treatment of psychosis in patients with Alzheimer’s disease: a randomized, placebo-controlled studyJ Clin Psychopharmacol200525546346716160622
- StreimJEBrederCSwaninkRFlexible dose aripiprazole in psychosis of Alzheimer’s dementia (poster)Presented at the 157th American Psychiatric Association Meeting2004
- MintzerJETuneLEBrederCDAripiprazole for the treatment of psychoses in institutionalized patients with Alzheimer dementia: a multicenter, randomized, double-blind, placebo-controlled assessment of three fixed dosesAm J Geriatr Psychiatry2007151191893117974864
- FriedmanJHBermanRMGoetzCGOpen-label flexible-dose pilot study to evaluate the safety and tolerability of aripiprazole in patients with psychosis associated with Parkinson‘s diseaseMov Disord200621122078208117013906
- KeckPEJrCalabreseJRMcQuadeRDA randomized, double-blind, placebo-controlled 26-week trial of aripiprazole in recently manic patients with bipolar I disorderJ Clin Psychiatry200667462663716669728
- KeckPEJrMarcusRTourkodimitrisSA placebo-controlled, double-blind study of the efficacy and safety of aripiprazole in patients with acute bipolar maniaAm J Psychiatry200316091651165812944341
- SachsGSanchezRMarcusRAripiprazole in the treatment of acute manic or mixed episodes in patients with bipolar I disorder: a 3-week placebo-controlled studyJ Psychopharmacol200620453654616401666
- YoungRCBiggsJTZieglerVEMeyerDAA rating scale for mania: reliability, validity and sensitivityBr J Psychiatry1978133429435728692
- HamiltonMA rating scale for depressionJ Neurol Neurosurg Psychiatry196023566214399272
- AndrezinaRJosiassenRCMarcusRNIntramuscular aripiprazole for the treatment of acute agitation in patients with schizophrenia or schizoaffective disorder: a double-blind, placebo-controlled comparison with intramuscular haloperidolPsychopharmacology (Berl)2006188328129216953381
- Tran-JohnsonTKSackDAMarcusRNAubyPMcQuadeRDOrenDAEfficacy and safety of intramuscular aripiprazole in patients with acute agitation: a randomized, double-blind, placebo-controlled trialJ Clin Psychiatry200768111111917284138
- RutherfordBSneedJMiyazakiMAn open trial of aripiprazole augmentation for SSRI non-remitters with late-life depressionInt J Geriatr Psychiatry2007221098699117340654
- SheffrinMDriscollHCLenzeEJPilot study of augmentation with aripiprazole for incomplete response in late-life depression: getting to remissionJ Clin Psychiatry200970220821319210951
- PetrieJLSahaARMcEvoyJPAripiprazole, a new atypical antipsychotic: Phase 2 clinical trial resultsEur Neuropsychopharmacol19977Suppl 2S227
- DanielDGSahaARIngenitoGAripiprazole: a novel antipsychotic: Overview of phase II study resultsInt J Neuropsychopharmacol20003Suppl 1S157
- MarderSRMcQuadeRDStockEAripiprazole in the treatment of schizophrenia: safety and tolerability in short-term, placebo-controlled trialsSchizophr Res2003612–312313612729864
- HildrumBMykletunAHoleTMidthjellKDahlAAAge-specific prevalence of the metabolic syndrome defined by the International Diabetes Federation and the National Cholesterol Education Program: the Norwegian HUNT 2 studyBMC Public Health2007722017727697
- McQuadeRDStockEMarcusRA comparison of weight change during treatment with olanzapine or aripiprazole: results from a randomized, double-blind studyJ Clin Psychiatry200465Suppl 18475615600384
- De HertMHanssensLvan WinkelRA case series: evaluation of the metabolic safety of aripiprazoleSchizophr Bull200733382383016940338
- NewcomerJWCamposJAMarcusRNA multicenter, randomized, double-blind study of the effects of aripiprazole in overweight subjects with schizophrenia or schizoaffective disorder switched from olanzapineJ Clin Psychiatry20086971046105618605811
- Quality of life compendiuCenter for Quality of Life Research in Nursing Science Section for Nursing Science, Department of Public Health and Primary Health Care, University of BergenURL: http://www.uib.no/isf/people/doc/qol/httoc.htm Accessed August 28, 2009.
- HanssensLL’ItalienGLozeJYMarcusRNPansMKerselaersWThe effect of antipsychotic medication on sexual function and serum prolactin levels in community-treated schizophrenic patients: results from the Schizophrenia Trial of Aripiprazole (STAR) study (NCT00237913)BMC Psychiatry200889519102734
- TaylorDHanssensLLozeJYPansML’ItalienGMarcusRNPreference of medicine and patient-reported quality of life in community-treated schizophrenic patients receiving aripiprazole vs standard of care: results from the STAR studyEur Psychiatry200823533634318423987
- KasperSLermanMNMcQuadeRDEfficacy and safety of aripiprazole vs haloperidol for long-term maintenance treatment following acute relapse of schizophreniaInt J Neuropsychopharmacol20036432533714609439
- McGavinJKGoaKLAripiprazoleCNS Drugs20021611779786 discussion 787–778.12383035
- CaseyDECarsonWHSahaARSwitching patients to aripiprazole from other antipsychotic agents: a multicenter randomized studyPsychopharmacology (Berl)2003166439139912610718
- El-SayehHGMorgantiCAripiprazole for schizophreniaCochrane Database Syst Rev20062CD00457816625607
- KasperSResingerECognitive effects and antipsychotic treatmentPsychoneuroendocrinology200328Suppl 1273812504070
- LublinHEberhardJLevanderSCurrent therapy issues and unmet clinical needs in the treatment of schizophrenia: a review of the new generation antipsychoticsInt Clin Psychopharmacol200520418319815933479
- KernRSGreenMFCornblattBAThe neurocognitive effects of aripiprazole: an open-label comparison with olanzapinePsychopharmacology (Berl)2006187331232016810506
- CaseyDEMetabolic issues and cardiovascular disease in patients with psychiatric disordersAm J Med2005118Suppl 215S22S15903291
- BassonBRKinonBJTaylorCCSzymanskiKAGilmoreJATollefsonGDFactors influencing acute weight change in patients with schizophrenia treated with olanzapine, haloperidol, or risperidoneJ Clin Psychiatry200162423123811379836
- StreetJSClarkWSGannonKSOlanzapine treatment of psychotic and behavioral symptoms in patients with Alzheimer disease in nursing care facilities: a double-blind, randomized, placebo-controlled trial. The HGEU Study GroupArch Gen Psychiatry2000571096897611015815
- ParkSParkHTogoFYear-long physical activity and metabolic syndrome in older Japanese adults: cross-sectional data from the Nakanojo StudyJ Gerontol A Biol Sci Med Sci200863101119112318948564
- StewartKJBacherACTurnerKExercise and risk factors associated with metabolic syndrome in older adultsAm J Prev Med2005128191815626550
- SolomonDKPortnerTSBassGEClinical and economic outcomes in the hypertension and COPD arms of a multicenter outcomes studyJ Am Pharm Assoc (Wash)19983855745859782691
- SchoenMDDiDomenicoRJConnorSEDischlerJEBaumanJLImpact of the cost of prescription drugs on clinical outcomes in indigent patients with heart diseasePharmacotherapy200121121455146311765297
- MaguraSLaudetABMahmoodDRosenblumAKnightEAdherence to medication regimens and participation in dual-focus self-help groupsPsychiatr Serv200253331031611875225
- KellyGRScottJEMamonJMedication compliance and health education among outpatients with chronic mental disordersMed Care19902812118111972250501
- CorrissDJSmithTEHullJWLimRWPrattSIRomanelliSInteractive risk factors for treatment adherence in a chronic psychotic disorders populationPsychiatry Res199989326927410708273
- WeidenPJOlfsonMCost of relapse in schizophreniaSchizophr Bull19952134194297481573
- GreenJHFrequent rehospitalization and noncompliance with treatmentHosp Community Psychiatry19883999639663215645
- OlfsonMMechanicDHansellSBoyerCAWalkupJWeidenPJPredicting medication noncompliance after hospital discharge among patients with schizophreniaPsychiatr Serv200051221622210655006
- SunSXLiuGGChristensenDBFuAZReview and analysis of hospitalization costs associated with antipsychotic nonadherence in the treatment of schizophrenia in the United StatesCurr Med Res Opin200723102305231217697454
- JesteDVBlazerDCaseyDACNP White Paper: update on use of antipsychotic drugs in elderly per sons with dementiaNeuropsychopharmacology200833595797017637610
- CrismonMLArgoTRBuckleyPFSchizophreniaDiPiroJTTalbertRLYeeGCPharmacotherapy: A Pathophysiologic Approach7th edNew YorkMcGraw-Hill200810991123