Hypoxia-ischemia and retinal ganglion cell damage

References

• AbramovAYScorzielloADuchenMR2007Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenationJ Neurosci2711293817267568
   PubMed Web of Science ®Google Scholar
• Abu-El-AsrarAMDralandsLMissottenL2004Expression of apoptosis markers in the retinas of human subjects with diabetesInvest Ophthalmol Vis Sci452760615277502
   PubMed Web of Science ®Google Scholar
• AdachiMTakahashiKNishikawaM1996High intraocular pressure-induced ischemia and reperfusion injury in the optic nerve and retina in ratsGraefes Arch Clin Exp Ophthalmol234445518817288
   PubMed Web of Science ®Google Scholar
• AllenJWViciniSFadenAI2001Exacerbation of neuronal cell death by activation of group I metabotropic glutamate receptors: role of NMDA receptors and arachidonic acid releaseExp Neurol1694496011358458
   PubMed Web of Science ®Google Scholar
• AmesA1992Energy requirements of CNS cells as related to their function and to their vulnerability to ischemia: a commentary based on studies on retinaCan J Physiol Pharmacol70SupplS158641295666
   PubMed Web of Science ®Google Scholar
• AminRHFrankRNKennedyA1997Vascular endothelial growth factor is present in glial cells of the retina and optic nerve of human subjects with nonproliferative diabetic retinopathyInvest Ophthalmol Vis Sci3836479008628
   PubMed Web of Science ®Google Scholar
• AndersonBSaltzmanHA1964Retinal oxygen utilization measured by hyperbaric blackoutArch Ophthalmol72792514205438
   PubMedGoogle Scholar
• AntcliffRJMarshallJ1999The pathogenesis of edema in diabetic maculopathySemin Ophthalmol142233210758223
   PubMedGoogle Scholar
• AshtonNKokDAFouldsWS1963Ocular pathology in macroglobulinaemiaJ Pathol Bacteriol864536114068954
   PubMedGoogle Scholar
• AwadHHubertGWSmithY2000Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleusJ Neurosci207871911050106
   PubMed Web of Science ®Google Scholar
• BanasiakKJHaddadGG1998Hypoxia-induced apoptosis: effect of hypoxic severity and role of p53 in neuronal cell deathBrain Res7972953049666152
   PubMed Web of Science ®Google Scholar
• BeckmanJSBeckmanTWChenJ1990Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxideProc Natl Acad Sci U S A871620242154753
   PubMed Web of Science ®Google Scholar
• BenvenisteHDrejerJSchousboeA1984Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysisJ Neurochem431369746149259
   PubMed Web of Science ®Google Scholar
• BernaudinMNedelecASDivouxD2002Normobaric hypoxia induces tolerance to focal permanent cerebral ischemia in association with an increased expression of hypoxia-inducible factor-1 and its target genes, erythropoietin and VEGF, in the adult mouse brainJ Cereb Blood Flow Metab2239340311919510
   PubMed Web of Science ®Google Scholar
• BetzALSchielkeGPYangGY1996Interleukin-1 in cerebral ischemiaKeio J Med4523078897766
   PubMedGoogle Scholar
• BlockFSchwarzM1997Effects of antioxidants on ischemic retinal dysfunctionExp Eye Res64559649227274
   PubMed Web of Science ®Google Scholar
• BobynPJFranklinJLWallCM2002The effects of dietary sulfur amino acid deficiency on rat brain glutathione concentration and neural damage in global hemispheric hypoxia-ischemiaNutr Neurosci54071612509070
   PubMed Web of Science ®Google Scholar
• BojeKMAroraPK1992Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell deathBrain Res58725061381982
   PubMed Web of Science ®Google Scholar
• BolanosJPAlmeidaA1999Roles of nitric oxide in brain hypoxia-ischemiaBiochim Biophys Acta14114153610320673
   PubMed Web of Science ®Google Scholar
• BonaEAnderssonALBlomgrenK1999Chemokine and inflammatory cell response to hypoxia–ischemia in immature ratsPediatr Res45500910203141
   PubMed Web of Science ®Google Scholar
• BonmannESuschekCSprangerM1997The dominant role of exogenous or endogenous interleukin-1 beta on expression and activity of inducible nitric oxide synthase in rat microvascular brain endothelial cellsNeurosci Lett230109129259476
   PubMed Web of Science ®Google Scholar
• BordiFUgoliniA1999Group I metabotropic glutamate receptors: implications for brain diseasesProg Neurobiol59557910416961
   PubMed Web of Science ®Google Scholar
• BrandstätterJHKoulenPWässleH1998Diversity of glutamate receptors in the mammalian retinaVision Res381385979667006
   PubMed Web of Science ®Google Scholar
• BresnickGH1983Diabetic maculopathy. A critical review highlighting diffuse macular edemaOphthalmology901301176664669
   PubMed Web of Science ®Google Scholar
• BresslerNMBresslerSBFineSLSchachatAP2001Neovascular (exudative) age-related macular degenerationRetinaSt. Louis, MOMosby110035
   Google Scholar
• BrownGCMagargalLE1988The ocular ischemic syndrome. Clinical, fluorescein angiographic and carotid angiographic featuresInt Ophthalmol11239513182177
   PubMed Web of Science ®Google Scholar
• BrunoVBattagliaGKsiazekI2000Selective activation of mGlu4 metabotropic glutamate receptors is protective against excitotoxic neuronal deathJ Neurosci2064132010964947
   PubMed Web of Science ®Google Scholar
• BuchiER1992Cell death in the rat retina after a pressure-induced ischemia-reperfusion insult: an electron microscopic study, I: Ganglion cell layer and inner nuclear layerExp Eye Res55605131483506
   PubMed Web of Science ®Google Scholar
• BuckleySAJamesB1996Purtscher’s retinopathyPostgrad Med J72409128935600
   PubMed Web of Science ®Google Scholar
• BuissonAChoiDW1995The inhibitory mGluR agonist, S-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal deathNeuropharmacology34108178532157
   PubMed Web of Science ®Google Scholar
• BuissonAYuSPChoiDW1996DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neuronsEur J Neurosci8138438713457
   PubMed Web of Science ®Google Scholar
• BurtrumDSilversteinFS1994Hypoxic-ischemic brain injury stimulates glial fibrillary acidic protein mRNA and protein expression in neonatal ratsExp Neurol12611288157121
   PubMed Web of Science ®Google Scholar
• CarmelietP2003Angiogenesis in health and diseaseNat Med96536012778163
   PubMed Web of Science ®Google Scholar
• ChanPH1994Oxygen radicals in focal cerebral ischemiaJ Brain Pathol45965
   PubMed Web of Science ®Google Scholar
• ChanPH1996Role of oxidants in ischemic brain damageStroke27112498650725
   PubMed Web of Science ®Google Scholar
• Charriaut-MarlangueCMargaillIBorregaF1996bNG-nitro-L-arginine methyl ester reduces necrotic but not apoptotic cell death induced by reversible focal ischemia in ratEur J Pharmacol310137408884209
   PubMed Web of Science ®Google Scholar
• Charriaut-MarlangueCPollardHBen-AriY1996aIs ischemic cell death of the apoptotic type?Adv Neurol71425308790818
   PubMedGoogle Scholar
• ChenHLPistollatoFHoeppnerDJ2007Oxygen tension regulates survival and fate of mouse central nervous system precursors at multiple levelsStem Cells25229130117556599
   PubMed Web of Science ®Google Scholar
• ChenJGrahamSHNakayamaM1997Apoptosis repressor genes Bcl-2 and Bcl-x-long are expressed in the rat brain following global ischemiaJ Cereb Blood Flow Metab172108978381
   PubMed Web of Science ®Google Scholar
• ChenJZhuRLNakayamaMExpression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemiaJ Neurochem6764718667027
   PubMed Web of Science ®Google Scholar
• ChidlowGOsborneNN2003Rat retinal ganglion cell loss caused by kainate, NMDA and ischemia correlates with a reduction in mRNA and protein of Thy-1 and neurofilament lightBrain Res96329830612560136
   PubMed Web of Science ®Google Scholar
• ChoppMLiY1996Apoptosis in focal cerebral ischemiaActa Neurochir Suppl662168780792
   PubMedGoogle Scholar
• ChungHSHarrisAEvansDW1999Vascular aspects in the pathophysiology of glaucomatous optic neuropathySurv Ophthalmol43Suppl 1S435010416746
   PubMed Web of Science ®Google Scholar
• CohenLHNoellWKGraymoreCN1965Relationships between visual function and metabolismBiochemistry of the RetinaOrlando, FlaAcademic Press Inc3650
   Google Scholar
• ConnJPPinJP1997Pharmacology and functions of metabotropic glutamate receptorsAnn Rev Pharmacol Toxicol37205379131252
   PubMed Web of Science ®Google Scholar
• CostaVPHarrisAStefánssonE2003The effects of antiglaucoma and systemic medications on ocular blood flowProg Retin Eye Res2276980514575724
   PubMed Web of Science ®Google Scholar
• CowellRMXuHGalassoJM2002Hypoxic-ischemic injury induces macrophage inflammatory protein-1alpha expression in immature rat brainStroke3379580111872906
   PubMed Web of Science ®Google Scholar
• CoyleJTPuttfarckenP1993Oxidative stress, glutamate, and neurode-generative disordersScience262689957901908
   PubMed Web of Science ®Google Scholar
• CrollSDRansohoffRMCaiN2004VEGF-mediated inflammation precedes angiogenesis in adult brainExp Neurol18738840215144865
   PubMed Web of Science ®Google Scholar
• Cunha-VazJGTravassosA1984Breakdown of the blood-retinal barriers and cystoid macular edemaSurv Ophthalmol28S48592
   PubMed Web of Science ®Google Scholar
• DanboltNC2001Glutamate uptakeProg Neurobiol65110511369436
   PubMed Web of Science ®Google Scholar
• DavisMDBlodiBASchachatAP2001Proliferative diabetic retinopathyRetinaSt. Louis, MOMosby130949
   Google Scholar
• DawsonVLDawsonTMLondonED1991Nitric oxide mediates glutamate neurotoxicity in primary cortical culturesProc Natl Acad Sci U S A886368711648740
   PubMed Web of Science ®Google Scholar
• DeAKruegerJMSimaskoSM2005Glutamate induces the expression and release of tumor necrosis factor-alpha in cultured hypothalamic cellsBrain Res1053546116040010
   PubMed Web of Science ®Google Scholar
• De VriesCEscobedoJAUenoH1992The fms-like tyrosine kinase, a receptor for vascular endothelial growth factorScience255989911312256
   PubMed Web of Science ®Google Scholar
• del-ZoppoGJSchmid-SchonbeinGWMoriE1991Polymorpho-nuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboonsStroke221276831926239
   PubMed Web of Science ®Google Scholar
• DessiFCharriaut-MarlangueCKhrestchatiskyM1993Glutamate- induced neuronal death is not a programmed cell death in cerebellar culturesJ Neurochem60195358097239
   PubMed Web of Science ®Google Scholar
• DranceSMDouglasGRWijsmanK1988Response of blood flow to warm and cold in normal and low-tension glaucoma patientsAm J Ophthalmol1053593337192
   PubMed Web of Science ®Google Scholar
• DreyerEB1998A proposed role for excitotoxicity in glaucomaJ Glaucoma76279493118
   PubMed Web of Science ®Google Scholar
• DuganLLSensiSLCanzonieroLM1995Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-d-aspartateJ Neurosci156377887472402
   PubMed Web of Science ®Google Scholar
• FerraraN2001Role of vascular endothelial growth factor in regulation of physiological angiogenesisAm J Physiol Cell Physiol280C13586611350730
   PubMed Web of Science ®Google Scholar
• FeuersteinGWangXBaroneFC1998Cytokines in brain ischemia – the role of TNF alphaCell Mol Neurobiol186957019876875
   PubMed Web of Science ®Google Scholar
• FinkKZhuJNamuraS1998Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activationJ Cereb Blood Flow Metab18107169778183
   PubMed Web of Science ®Google Scholar
• FitzjohnSMIrvingAJPalmerMJ1996Activation of group I mGluRs potentiates NMDA responses in rat hippocampal slicesNeurosci Lett20321138742030
   PubMed Web of Science ®Google Scholar
• FlammerJ1994The vascular concept of glaucomaSurv Ophthalmol38SupplS367940146
   PubMedGoogle Scholar
• FukumuraDGohongiTKadambiA2001Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeabilityProc Natl Acad Sci U S A982604911226286
   PubMed Web of Science ®Google Scholar
• Garcia-ValenzuelaEShareefSWalshJ1995Programmed cell death of retinal ganglion cells during experimental glaucomaExp Eye Res6133447556468
   PubMed Web of Science ®Google Scholar
• GarthwaiteGGarthwaiteJ1991AMPA neurotoxicity in rat cerebellar and hippocampal slices: histological evidence for three mechanismsEur J Neurosci37152812106458
   PubMed Web of Science ®Google Scholar
• GarthwaiteJCharkesSLChess-WilliamsR1988Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brainNature33638582904125
   PubMed Web of Science ®Google Scholar
• GarthwaiteJ1991Glutamate, nitric oxide and cell-cell signalling in the nervous systemTrends Neurosci146071708538
   PubMed Web of Science ®Google Scholar
• GhezziPDinarelloCABianchiM1991Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cellsCytokine3189941883957
   PubMed Web of Science ®Google Scholar
• GotoWOtaTMorikawaN2002Protective effects of timolol against the neuronal damage induced by glutamate and ischemia in the rat retinaBrain Res95810912468025
   PubMed Web of Science ®Google Scholar
• GrossWLBakMIIngwallJS1996Nitric oxide inhibits creatine kinase and regulates rat heart contractile reservesProc Natl Acad Sci U S A93560498643623
   PubMed Web of Science ®Google Scholar
• GründerTKohlerKGuentheE2001Alterations in NMDA receptor expression during retinal degeneration in the RCS ratVis Neurosci18781711925013
   PubMed Web of Science ®Google Scholar
• Guex-CrosierY1999The pathogenesis and clinical presentation of macular edema in inflammatory diseasesDoc Ophthalmol9729730910896343
   PubMed Web of Science ®Google Scholar
• GwagBJKohJYDemaroJ1997Slowly triggered excitotoxicity occurs by necrosis in cortical culturesNeuroscience773934019472399
   PubMed Web of Science ®Google Scholar
• HaganPPooleSBristowAF1996Intracerebral NMDA injection stimulates production of interleukin-1β in perinatal rat brainJ Neurochem67221588863535
   PubMed Web of Science ®Google Scholar
• HaldarSChintapalliJCroceCM1996Taxol induces bcl-2 phosphorylation and death of prostate cancer cellsCancer Res562535
   Web of Science ®Google Scholar
• HallEDBraughlerJM1989Central nervous system trauma and stroke. II. Physiological and pharmacological evidence for involvement of oxygen radicals and lipid peroxidationFree Radic Biol Med6303132663663
   PubMed Web of Science ®Google Scholar
• HamannKF2002[Driving ability with vestibulär lesions]HNO501086812474132
   PubMed Web of Science ®Google Scholar
• HamannSla CourM2005Water homeostasis in the ischaemic retina: is aquaporin-4 involved?Acta Ophthalmol Scand83523516187986
   PubMedGoogle Scholar
• HaradaTHaradaCNakamuraK2007The potential role of glutamate transporters in the pathogenesis of normal tension glaucomaJ Clin Invest11717637017607354
   PubMed Web of Science ®Google Scholar
• HarrisAL2002Hypoxia – a key regulatory factor in tumour growthNat Rev Cancer2384711902584
   PubMed Web of Science ®Google Scholar
• HartveitEBrandstätterJHEnzR1995Expression of the mRNA of seven metabotropic glutamate receptors (mGluR1–7) in the rat retina. An in situ hybridization study on tissue sections and isolated cellsEur J Neurosci71472837551173
   PubMed Web of Science ®Google Scholar
• HartveitEBrandstätterJHSassoè-PognettoM1994Localization and developmental expression of the NMDA receptor subunit NR2A in the mammalian retinaJ Comp Neurol348570827836563
   PubMed Web of Science ®Google Scholar
• HedtjärnMMallardCHagbergH2004Inflammatory gene profiling in the developing mouse brain after hypoxia-ischemiaJ Cereb Blood Flow Metab243351
   Web of Science ®Google Scholar
• HeinelLARubinSRosenwasserRH1994Leukocyte involvement in cerebral infarct generation after ischemia and reperfusionBrain Res Bull34137418044688
   PubMed Web of Science ®Google Scholar
• HessDCBhutwalaTSheppardJC1994ICAM-1 expression on human brain microvascular endothelial cellsNeurosci Lett16820147913216
   PubMed Web of Science ®Google Scholar
• HiltonGDNunezJLBambrickL2006Glutamate-mediated excitotoxicity in neonatal hippocampal neurons is mediated by mGluR-induced release of Ca++ from intracellular stores and is prevented by estradiolEur J Neurosci2430081617156362
   PubMed Web of Science ®Google Scholar
• HollmannMHartleyMHeinemannS1991Ca2+ permeability of KA-AMPA – gated glutamate receptor channels depends on subunit compositionScience25285131709304
   PubMed Web of Science ®Google Scholar
• HuYBenedictMAWuD1998Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activationProc Natl Acad Sci U S A94386919539746
   PubMed Web of Science ®Google Scholar
• IadecolaCPelligrinoDAMoskowitzMA1994State of the art review: nitric oxide synthase inhibition and cerebrovascular regulationJ Cereb Blood Flow Meta1417592
   PubMed Web of Science ®Google Scholar
• IadecolaC1997Bright and dark sides of nitric oxide in ischemic brain injuryTrends Neurosci2013299061868
   PubMed Web of Science ®Google Scholar
• IkedaEAchenMGBreierG1995Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cellsJ Biol Chem2701976167544346
   PubMed Web of Science ®Google Scholar
• IvakoJMalinakCMalinakC1997Hypoxic ischemic injury induces monocyte chemoattractant protein 1 expression in neonatal rat brainJ Cereb Blood Flow Metab17759709270493
   PubMed Web of Science ®Google Scholar
• IvakoJSilversteinFSSilversteinFS1996Hypoxic ischemic brain injury induces an acute microglial reaction inperinatal ratsPediat Res3939478825384
   PubMed Web of Science ®Google Scholar
• IyerNVKotchLEAganiF1998Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alphaGenes Dev12149629436976
   PubMed Web of Science ®Google Scholar
• JacksonTLHillenkampJWilliamsonTH2003An experimental model of rhegmatogenous retinal detachment: surgical results and glial cell responseInvest Ophthalmol Vis Sci4440263412939325
   PubMed Web of Science ®Google Scholar
• JacobsonMDEvanGI1994Apoptosis. Breaking the ICECurr Biol4337407857398
   PubMed Web of Science ®Google Scholar
• JanákyMGrószATóthE2007Hypobaric hypoxia reduces the amplitude of oscillatory potentials in the human ERGDoc Ophthalmol114455117211646
   PubMed Web of Science ®Google Scholar
• JänickeRUSprengartMLWatiMR1998Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosisJ Biol Chem2739357609545256
   PubMed Web of Science ®Google Scholar
• JiaZLuYHendersonJ1998Selective abolition of the NMDA component of long-term potentiation in mice lacking mGluR5Learn Mem53314310454358
   PubMed Web of Science ®Google Scholar
• JoNWuGSRaoNA2003Upregulation of chemokine expression in the retinal vasculature in ischemia-reperfusion injuryInvest Ophthalmol Vis Sci4440546012939328
   PubMed Web of Science ®Google Scholar
• JohnsonNF1974Effects of acute ischemia on the structure of the rabbit retinaTrans Ophthalmol Soc Uk943944054534186
   PubMedGoogle Scholar
• JooCKChoiJSKoHW1999Necrosis and apoptosis after retinal ischemia: involvement of NMDA-mediated excitotoxicity and p53Invest Ophthalmol Vis Sci407132010067975
   PubMed Web of Science ®Google Scholar
• JooCKParkKYParkMS1996Occurrence of neuronal necrosis and apoptosis following the retinal ischemia: induction of p53 and bcl-2 mRNASoc Neurosci Abstr2646415
   Google Scholar
• JoussenAMPoulakiVLeML2004A central role for inflammation in the pathogenesis of diabetic retinopathyFASEB J181450215231732
   PubMed Web of Science ®Google Scholar
• JoussenAMPoulakiVQinW2002Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivoAm J Pathol160501911839570
   PubMed Web of Science ®Google Scholar
• KadhimHKhalifaMDeltenreP2006Molecular mechanisms of cell death in periventricular leukomalaciaNeurology67293916864823
   PubMed Web of Science ®Google Scholar
• KanedaKKashiiSKurosawaT1999Apoptotic DNA fragmentation and upregulation of Bax induced by transient ischemia of the rat retinaBrain Res81511209974117
   PubMed Web of Science ®Google Scholar
• KashiwagiKIizukaYMochizukiS2003Differences in nitric oxide production: a comparison of retinal ganglion cells and retinal glial cells cultured under hypoxic conditionsBrain Res Mol Brain Res1121263412670710
   PubMedGoogle Scholar
• KatsuraKKristianTSiesjoBK1994Energy metabolism, ion homeostasis, and cell damage in the brainBiochem Soc Trans2299167698500
   PubMed Web of Science ®Google Scholar
• KaurCSivakumarVFouldsWS2006Early response of neurons and glial cells to hypoxia in the retinaInvest Ophthalmol Vis Sci4711264116505051
   PubMed Web of Science ®Google Scholar
• KaurCSivakumarVYongZ2007Blood-retinal barrier disruption and ultrastructural changes in the hypoxic retina in adult rats: the beneficial effect of melatonin administrationJ Pathol2124293917582234
   PubMed Web of Science ®Google Scholar
• KergoatHHérardMELemayM2006RGC sensitivity to mild systemic hypoxiaInvest Ophthalmol Vis Sci475423717122132
   PubMed Web of Science ®Google Scholar
• KerriganLAZackDJQuigleyHA1997TUNEL-positive ganglion cells in human primary open-angle glaucomaArch Ophthalmol11510315
   Google Scholar
• KissJPViziES2001Nitric oxide: a novel link between synaptic and nonsynaptic transmissionTrends Neurosci24211511250004
   PubMed Web of Science ®Google Scholar
• KitagawaKMatsumotoMTagayaM1990Ischemic tolerance’ phenomenon found in the brainBrain Res5282142245337
   PubMed Web of Science ®Google Scholar
• KobayashiMKuroiwaTShimokawaR2000Nitric oxide synthase expression in ischemic rat retinasJpn J Ophthalmol442354410913641
   PubMed Web of Science ®Google Scholar
• KortuemKGeigerLKLevinLA2000Differential susceptibility of retinal ganglion cells to reactive oxygen speciesInvest Ophthalmol Vis Sci4131768210967081
   PubMed Web of Science ®Google Scholar
• KrajewskiSMaiJKKrajewskaM1995Upregulation of bax protein levels in neurons following cerebral ischemiaJ Neurosci156364767472401
   PubMed Web of Science ®Google Scholar
• KuroiwaTTingPMartinezH1985The biphasic opening of the blood-brain barrier to proteins following temporary middle cerebral artery occlusionActa Neuropathol (Berl)6812293907257
   PubMed Web of Science ®Google Scholar
• KurokawaHNishioKFukumotoH1999Alteration of caspase-3 (CPP32/Yama/apopain) in wild-type MCF-7, breast cancer cellsOncol Rep63379864397
   PubMed Web of Science ®Google Scholar
• LafuenteMPVillegas-PerezMPSells-NavarroI2002Retinal ganglion cell death after acute retinal ischemia is an ongoing process whose severity and duration depends on the duration of the insultNeuroscience1091576811784707
   PubMed Web of Science ®Google Scholar
• LamTTAblerASTsoMO1999Apoptosis and caspases after ischemia-reperfusion injury in rat retinaInvest Ophthalmol Vis Sci409677510102294
   PubMed Web of Science ®Google Scholar
• LamasSMarsdenPALiGK1992Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoformProc Natl Acad Sci U S A896348521378626
   PubMed Web of Science ®Google Scholar
• LeesGJ1993The possible contribution of microglia and macrophages to delayed neuronal death after ischemiaJ Neurol Sci114119228445391
   PubMed Web of Science ®Google Scholar
• Levkovitch-VerbinHHarris-CerrutiCGronerY2000RGC death in mice after optic nerve crush injury: oxidative stress and neuroprotectionInvest Ophthalmol Vis Sci4141697411095611
   PubMed Web of Science ®Google Scholar
• LevyAPLevyNSWegnerS1995Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxiaJ Biol Chem27013333407768934
   PubMed Web of Science ®Google Scholar
• LiTQMathewsVPWangY2005Adolescents with disruptive behavior disorder investigated using an optimized MR diffusion tensor imaging protocolAnn N Y Acad Sci10641849216394156
   PubMed Web of Science ®Google Scholar
• LievenCJSchlieveCRHoeggerMJ2006Retinal ganglion cell axotomy induces an increase in intracellular superoxide anionInvest Ophthalmol Vis Sci4714778516565382
   PubMed Web of Science ®Google Scholar
• LievenCJVrabecJPLevinLA2003The effects of oxidative stress on mitochondrial transmembrane potential in retinal ganglion cellsAntioxid Redox Signal5641614580321
   PubMed Web of Science ®Google Scholar
• LinsenmeierRABraunRDMcRipleyMA1998Retinal hypoxia in long-term diabetic catsInvest Ophthalmol Vis Sci391647579699554
   PubMed Web of Science ®Google Scholar
• LiptonSAChoiYBPanZH1993A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compoundsNature364626328394509
   PubMed Web of Science ®Google Scholar
• López-FigueroaMODayHELeeS2000Temporal and anatomical distribution of nitric oxide synthase mRNA expression and nitric oxide production during central nervous system inflammationBrain Res8522394610661521
   PubMed Web of Science ®Google Scholar
• Louzada-JuniorPDiasJJSantosWF1992Glutamate release in experimental ischaemia of the retina: an approach using microdialysisJ Neurochem59358631351929
   PubMed Web of Science ®Google Scholar
• LuMPerezVMaN1999VEGF increases retinal vascular ICAM-1 expression in vivoInvest Ophthalmol Vis Sci4018081210393052
   PubMed Web of Science ®Google Scholar
• LuYLuBFZhaoFQ1993Accumulation of glutamate is regulated by calcium and protein kinase C in rat hippocampal slices exposed to ischemic statesHippocampus322178102581
   PubMed Web of Science ®Google Scholar
• MacayaA1996[Apoptosis in the nervous system]Rev Neurol241356608974737
   PubMedGoogle Scholar
• MacDermottABMayerMLWestbrookGL1986NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neuronesNature321519223012362
   PubMed Web of Science ®Google Scholar
• MacManusJPLinnikMD1997Gene expression induced by cerebral ischemia: an apoptotic perspectiveJ Cereb Blood Flow Metab17815329290580
   PubMed Web of Science ®Google Scholar
• MacManusJPLinnikMD1997Gene expression induced by cerebral ischemia: an apoptotic perspectiveJ Cereb Blood Flow Metab17815329290580
   PubMed Web of Science ®Google Scholar
• MarmorMF1999Mechanisms of fluid accumulation in retinal edemaDoc Ophthalmol972394910896337
   PubMed Web of Science ®Google Scholar
• MarumoTNollTSchini-KerthVB1999Significance of nitric oxide and peroxynitrite in permeability changes of the retinal microvascular endothelial cell monolayer induced by vascular endothelial growth factorJ Vasc Res365101510629427
   PubMed Web of Science ®Google Scholar
• MasseySC1990Cell types using glutamate as a neurotransmitter in the vertebrate retinaProgr Retinal Res9399425
   Google Scholar
• MatuteCAlberdiEDomercqM2001The link between excitotoxic oligodendroglial death and demyelinating diseasesTrends Neurosci242243011250007
   PubMed Web of Science ®Google Scholar
• McHaleJFHarariOAMarshallD1999TNF-alpha and IL-1 sequentially induce endothelial ICAM-1 and VCAM-1 expression in MRL/lpr lupus-prone miceJ Immunol1633993400010491002
   PubMed Web of Science ®Google Scholar
• MehmetHYueXSquierMV1994Increased apoptosis in the cingulate sulcus of newborn piglets following transient hypoxia-ischaemia is related to the degree of high energy phosphate depletion during the insultNeurosci Lett18112157898750
   PubMed Web of Science ®Google Scholar
• MeisterAAndersonME1983GlutathioneAnnu Rev Biochem52711606137189
   PubMed Web of Science ®Google Scholar
• MelderRJKoenigGCWitwerBP1996During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endotheliumNat Med299278782456
   PubMed Web of Science ®Google Scholar
• MinJKKimYMKimSW2005TNF-related activation-induced cytokine enhances leukocyte adhesiveness: Induction of ICAM-1 and VCAM-1 via TNF receptor-associated factor and protein kinase C-dependent NFB activation in endothelial cellsThe Journal of Immunol17553140
   PubMed Web of Science ®Google Scholar
• MishraOPAshrafQMDelivoria-PapadopoulosM2002Phosphorylation of cAMP response element binding (CREB) protein during hypoxia in cerebral cortex of newborn piglets and the effect of nitric oxide synthase inhibitionNeuroscience1159859112435435
   PubMed Web of Science ®Google Scholar
• MishraOPZubrowABAshrafQM2006Nuclear Ca(++)-influx, Ca (++)/calmodulin-dependent protein kinase IV activity and CREB protein phosphorylation during post-hypoxic reoxygenation in neuronal nuclei of newborn piglets: the role of nitric oxideNeurochem Res3114637117091402
   PubMed Web of Science ®Google Scholar
• MishraOPZubrowABAshrafQM2004Nitric oxide-mediated activation of extracellular signal-regulated kinase (ERK) and c-jun N-terminal kinase (JNK) during hypoxia in cerebral cortical nuclei of newborn pigletsNeuroscience1231798614667452
   PubMed Web of Science ®Google Scholar
• MiyakeKIbarakiN2002Prostaglandins and cystoid macular edemaSurv Ophthalmol47S203812204717
   PubMed Web of Science ®Google Scholar
• MizuiTKinouchiHChanPH1992Depletion of brain glutathione by buthionine sulfoximine enhances cerebral ischemic injury in ratsAm J Physiol262H31371539690
   PubMed Web of Science ®Google Scholar
• MoncadaSPalmerRMHiggsEA1991Nitric oxide: physiology, pathophysiology, and pharmacologyPharmacol Rev43109421852778
   PubMed Web of Science ®Google Scholar
• MullerAPietriSVillainM1997Free radicals in rabbit retina under ocular hyperpressure and functional consequencesExp Eye Res64637439227282
   PubMed Web of Science ®Google Scholar
• MurataTNakagawaKKhalilA1996The relation between expression of vascular endothelial growth factor and breakdown of the blood retinal barrier in diabetic rat retinasLab Invest74819258606491
   PubMed Web of Science ®Google Scholar
• NakajimaWIshidaALangeMS2000Apoptosis has a prolonged role in the neurodegeneration after hypoxic ischemia in the newborn ratJ Neurosci207994800411050120
   PubMed Web of Science ®Google Scholar
• NamuraSZhuJFinkK1998Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemiaJ Neurosci183659689570797
   PubMed Web of Science ®Google Scholar
• NeufeldAHKawaiSDasS2002Loss of retinal ganglion cells following retinal ischemia: the role of inducible nitric oxide synthaseExp Eye Re755218
   PubMed Web of Science ®Google Scholar
• NeufeldGCohenTGengrinovitchS1999Vascular endothelial growth factor (VEGF) and its receptorsFASEB J139229872925
   PubMed Web of Science ®Google Scholar
• NguyenSMAlexejunCNLevinLA2003Amplification of a reactive oxygen species signal in axotomized retinal ganglion cellsAntioxid Redox Signal56293414580319
   PubMed Web of Science ®Google Scholar
• NguyenTBrunsonDCrespiCL1992DNA damage and mutation in human cells exposed to nitric oxide in vitroProc Natl Acad Sci U S A89303041557408
   PubMed Web of Science ®Google Scholar
• NicoteraPOrreniusS1998The role of calcium in apoptosisCell Calcium23173809601613
   PubMed Web of Science ®Google Scholar
• NodaMNakanishiHNabekuraJ2000AMPA–kainate subtypes of glutamate receptor in rat cerebral microgliaJ Neurosci20251810627602
   PubMed Web of Science ®Google Scholar
• OsborneNNCassonRJWoodJP2004Retinal ischemia: mechanisms of damage and potential therapeutic strategiesProg Retin Eye Res239114714766318
   PubMed Web of Science ®Google Scholar
• OsborneNNChidlowGNashMS1999The potential of neuroprotection in glaucoma treatmentCurr Opin Ophthalmol10829210537768
   PubMedGoogle Scholar
• PangIHWexlerEMNawyS1999Protection by eliprodil against excitotoxicity in cultured retinal ganglion cellsVis Sci4011706
   Google Scholar
• PinJPDuvoisinR1995The metabotropic glutamate receptors: structure and functionsNeuropharmacology341267623957
   PubMed Web of Science ®Google Scholar
• PrassKScharffARuscherK2003Hypoxia-induced stroke tolerance in the mouse is mediated by erythropoietinStroke341981612829864
   PubMed Web of Science ®Google Scholar
• ProescholdtMAHeissJDWalbridgeS1999Vascular endothelial growth factor (VEGF) modulates vascular permeability and inflammation in rat brainJ Neuropathol Exp Neurol586132710374752
   PubMed Web of Science ®Google Scholar
• ProescholdtMAJacobsonSTresserN2002Vascular endothelial growth factor is expressed in multiple sclerosis plaques and can induce inflammatory lesions in experimental allergic encephalomyelitis ratsJ Neuropathol Exp Neurol619142512387457
   PubMed Web of Science ®Google Scholar
• PuleraMRAdamsLMLiuH1998Apoptosis in a neonatal rat model of cerebral hypoxia-ischemiaStroke292622309836776
   PubMed Web of Science ®Google Scholar
• PurtscherO1912Angiopathia retinae traumatica: lymphorrhagien desaugengrundesGraefes Arch Klin Exp Ophthalmol8234771
   Google Scholar
• QuigleyHANickellsRWKerriganLA1995Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosisInvest Ophthalmol Vis Sci36774867706025
   PubMed Web of Science ®Google Scholar
• QuinnTPPetersKGDe VriesC1993Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endotheliumProc Natl Acad Sci U S A90753378356051
   PubMed Web of Science ®Google Scholar
• RatanRRMurphyTHBarabanJM1994Oxidative stress induces apoptosis in embryonic cortical neuronsJ Neurochem6237697903353
   PubMed Web of Science ®Google Scholar
• ReichenbachAWurmAPannickeT2007Müller cells as players in retinal degeneration and edemaGraefes Arch Clin Exp Ophthalmol2456273617219109
   PubMed Web of Science ®Google Scholar
• RenolleauSAggoun-ZouaouiDBen-AriY1998A model of transient unilateral focal ischemia with reperfusion in the P7 neonatal rat: morphological changes indicative of apoptosisStroke291454609660403
   PubMed Web of Science ®Google Scholar
• RörigBGrantynR1993Rat retinal ganglion cells express Ca(2+)-permeable non-NMDA glutamate receptors during the period of histogenetic cell deathNeurosci Lett1533268510821
   PubMed Web of Science ®Google Scholar
• SalgoMGBermúdezESquadritoGL1995Peroxynitrite causes DNA damage and oxidation of thiols in rat thymocytesArch Biochem Biophys32250057574726
   PubMed Web of Science ®Google Scholar
• SaltTEBinnsKE2000Contributions of mGlu1 and mGlu5 receptors to interactions with N-methyl-D-aspartate receptor-mediated responses and nociceptive sensory responses of rat thalamic neuronsNeuroscience1003758011008175
   PubMed Web of Science ®Google Scholar
• SalveminiDWangZSternM1998Peroxynitrite decomposition catalysts: therapeutics for peroxynitrite-mediated pathologyProc Natl Acad Sci U S A952695703
   Web of Science ®Google Scholar
• SattlerRTymianskiM2001Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell deathMol Neurobiol241–31072911831548
   PubMed Web of Science ®Google Scholar
• SchochHJFischerSMartiHH2002Hypoxia-induced vascular endothelial growth factor expression causes vascular leakage in the brainBrain12525495712390979
   PubMed Web of Science ®Google Scholar
• SengerDRPerruzziCAFederJ1986A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell linesCancer Res465629323756910
   PubMed Web of Science ®Google Scholar
• ShelhamerJHVolkmanDJParrilloJE1985Takayasu’s arteritis and its therapyAnn Intern Med10312162860834
   PubMed Web of Science ®Google Scholar
• ShibuyaMItoNClaesson-WelshL1999Structure and function of vascular endothelial growth factor receptor-1 and -2Curr Top Microbiol Immunol23759839893346
   PubMed Web of Science ®Google Scholar
• ShimazakiKIshidaAKawaiN1994Increase in bcl-2 oncoprotein and the tolerance to ischemia-induced neuronal death in the gerbil hippocampusNeurosci Res209597527133
   PubMed Web of Science ®Google Scholar
• SiliprandiRCanellaRCarmignotoG1992N-methyl-D-aspartate-induced neurotoxicity in the adult rat retinaVisual Neurosci856773
   PubMed Web of Science ®Google Scholar
• SohnSKimEYGwagBJ1998Glutamate neurotoxicity in mouse cortical neurons: atypical necrosis with DNA ladders and chromatin condensationNeurosci Lett240149488160
   PubMed Web of Science ®Google Scholar
• SouthamEGarthwaiteJ1993The nitric oxide-cyclic GMP signalling pathway in rat brainNeuropharmacology321267777509051
   PubMed Web of Science ®Google Scholar
• St ClairEGAndersonSJOltvaiZN1997Bcl-2 counters apoptosis by Bax heterodimerization-dependent and -independent mechanisms in the T-cell lineageJ Biol Chem27229347559361016
   PubMed Web of Science ®Google Scholar
• SteinINeemanMShweikiD1995Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genesMol Cell Biol15536387565686
   PubMed Web of Science ®Google Scholar
• SucherNJAizenmanELiptonSA1991NMDA antagonists prevent kainate neurotoxicity in rat retinal ganglion cellsJ Neurosci11966711672708
   PubMed Web of Science ®Google Scholar
• SucherNJLiptonSADreyerEB1997Molecular basis of glutamate toxicity in retinal ganglion cellsVision Res373483939425525
   PubMed Web of Science ®Google Scholar
• SucherNJWongLALiptonSA1990Redox modulation of NMDA receptor-mediated Ca2+ flux in mammalian central neuronsNeuroreport129322151794
   PubMedGoogle Scholar
• SzaboMEDroy-LefaixMTDolyM1997Direct measurement of free radicals in ischemic/reperfused diabetic rat retinaClin Neurosci424059292250
   PubMedGoogle Scholar
• SzaflarskiJBurtrumDSilversteinFS1995Cerebral hypoxia-ischemia stimulates cytokine gene expression in perinatal ratsStroke2610931007762028
   PubMed Web of Science ®Google Scholar
• TanSSagaraYLiuY1998The regulation of reactive oxygen species production during programmed cell deathJ Cell Biol1411423329628898
   PubMed Web of Science ®Google Scholar
• TezelGWaxMB2004The immune system and glaucomaCurr Opin Ophthalmol1580415021215
   PubMedGoogle Scholar
• TezelGYangX2004Caspase-independent component of retinal ganglion cell death, in vitroInvest Ophthalmol Vis Sci4540495915505055
   PubMed Web of Science ®Google Scholar
• TielschJMKatzJSommerA1995Hypertension, perfusion pressure, and primary open-angle glaucoma. A population-based assessmentArch Ophthalmol113216217864755
   PubMed Web of Science ®Google Scholar
• TinjustDKergoatHLovasikJV2002Neuroretinal function during mild systemic hypoxiaAviat Space Environ Med7311899412498547
   PubMed Web of Science ®Google Scholar
• TodaNNakanishi-TodaM2007Nitric oxide: ocular blood flow, glaucoma, and diabetic retinopathyProg Retin Eye Res262053817337232
   PubMed Web of Science ®Google Scholar
• TolentinoMJMillerJWGragoudasES1996Intravitreous injections of vascular endothelial growth factor produce retinal ischemia and microangiopathy in an adult primateOphthalmology10318201288942877
   PubMed Web of Science ®Google Scholar
• TsoMOM1982Pathology of cystoid macular oedemaOphthalmology89902157133637
   PubMed Web of Science ®Google Scholar
• van DamPS2002Oxidative stress and diabetic neuropathy: pathophysiological mechanisms and treatment perspectivesDiabetes Metab Res Rev181768412112935
   PubMed Web of Science ®Google Scholar
• WangJBeekhuizenHvan FurthR1994Surface molecules involved in the adherence of recombinant interferon-gamma (rIFN-gamma)-stimulated human monocytes to vascular endothelial cellsClin Exp Immunol9526397508346
   PubMed Web of Science ®Google Scholar
• WangQTangXNYenariMA2007The inflammatory response in strokeJ Neuroimmunol184536817188755
   PubMed Web of Science ®Google Scholar
• WangXNiwaMHaraA2002Neuronal degradation in mouse retina after a transient ischemia and protective effect of hypothermiaNeurol Res24730512392214
   PubMed Web of Science ®Google Scholar
• WaxMBTezelG2002Neurobiology of glaucomatous optic neuropathy: diverse cellular events in neurodegeneration and neuroprotectionMol Neurobiol26455512392055
   PubMed Web of Science ®Google Scholar
• WernsSWSheaMJLucchesiBR1985Free radicals in ischemic myocardial injuryJ Free Radic Biol Med1103103939137
   PubMedGoogle Scholar
• WongDDorovini-ZisK1992Upregulation of intercellular adhesion molecule-1 (ICAM-1) expression in primary cultures of human brain microvessel endothelial cells by cytokines and lipopolysaccharideJ Neuroimmunol3911211352310
   PubMed Web of Science ®Google Scholar
• WongMLBongiornoPBal-ShekhleeA1996IL-1 beta, IL-1 receptor type I and iNOS gene expression in rat brain vasculature and perivascular areasNeuroreport7244588981400
   PubMed Web of Science ®Google Scholar
• YanoffMFineBSBruckerAJ1984Pathology of human cystoid macular oedemaSurv Ophthalmol28 Suppl505116463850
   PubMed Web of Science ®Google Scholar
• YoshidaSYoshidaAIshibashiT2004Induction of IL-8, MCP-1, and bFGF by TNF-alpha in retinal glial cells: implications for retinal neovascularization during post-ischemic inflammationGraefes Arch Clin Exp Ophthalmol2424091315029502
   PubMed Web of Science ®Google Scholar
• YueXMehmetHPenriceJ1997Apoptosis and necrosis in the newborn piglet brain following transient cerebral hypoxia-ischaemiaNeuropathol Appl Neurobiol2316259061686
   PubMed Web of Science ®Google Scholar
• ZhangZGZhangLJiangQ2000VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brainJ Clin Invest1068293811018070
   PubMed Web of Science ®Google Scholar
• ZhangZGZhangLTsangW2002Correlation of VEGF and angiopoietin expression with disruption of blood-brain barrier and angiogenesis after focal cerebral ischemiaJ Cereb Blood Flow Metab223799211919509
   PubMed Web of Science ®Google Scholar
• ZhangRLChoppMChenH1994Temporal profile of ischemic tissue damage, neutrophil response, and vascular plugging following permanent and transient (2H) middle cerebral artery occlusion in the ratJ Neurol Sci1253107964886
   PubMed Web of Science ®Google Scholar
• ZhengLGongBHatalaDA2007Retinal ischemia and reperfusion causes capillary degeneration: similarities to diabetesInvest Ophthalmol Vis Sci48361717197555
   PubMed Web of Science ®Google Scholar
• ZubrowABDelivoria-PapadopoulosMAshrafQM2002aNitric oxide-mediated Ca2+/calmodulin-dependent protein kinase IV activity during hypoxia in neuronal nuclei from newborn pigletsNeurosci Lett3355812457729
   PubMed Web of Science ®Google Scholar
• ZubrowABDelivoria-PapadopoulosmMAshrafmQM2002bNitric oxide-mediated expression of Bax protein and DNA fragmentation during hypoxia in neuronal nuclei from newborn pigletsBrain Res95607
   Web of Science ®Google Scholar