Pathogenesis of thyroid-associated ophthalmopathy: does autoimmunity against calsequestrin and collagen XIII play a role?

References

• NabipourIBurgerAMoharreriMRAziziFAvicenna, the first to describe thyroid-related orbitopathyThyroid20091917819119980
   PubMed Web of Science ®Google Scholar
• BurchHBWartofskyBGraves’ ophthalmopathy: current concepts regarding pathogenesis and managementEndocr Rev19931467477938119236
   PubMed Web of Science ®Google Scholar
• YamadaMWu LiAWallJThyroid-associated ophthalmopathy: clinical features, pathogenesis, and managementCrit Rev Clin Lab Sci200037652354911192331
   PubMed Web of Science ®Google Scholar
• GopinathBAdamsCLMusselmanRTaniJWallJRAntibodies against calsequestrin and type XIII collagen are good markers for chronic upper eyelid retractionOcul Immunol Inflamm2007152818817558832
   PubMed Web of Science ®Google Scholar
• GopinathBMaGWallJREye signs and serum eye muscle and collagen XIII antibodies in patients with transient and progressive thyroiditisThyroid200717111123112917887926
   PubMed Web of Science ®Google Scholar
• TjiangHLahootiHMcCorquodaleTWallJREye and eyelid abnormalities are common in patients with Hashimoto’s thyroiditisThyroid2010 In Press.
   Web of Science ®Google Scholar
• CoulterIFrewinSKrassasGEPerrosPPsychological implications of Graves’ orbitopathyEur J Endocrinol2007157212713117656589
   PubMed Web of Science ®Google Scholar
• Della RoccaRCThyroid-related orbitopathy: concepts and managementFacial Plast Surg200723316817317691064
   PubMed Web of Science ®Google Scholar
• BusuttilBEFraumanAGExtrathyroidal manifestations of Graves’ disease: the thyrotropin receptor is expressed in extraocular, but not cardiac, muscle tissuesJ Clin Endocrinol Metab20018652315231911344244
   PubMed Web of Science ®Google Scholar
• TaniJWallJRAutoimmunity against eye-muscle antigens may explain thyroid-associated ophthalmopathyCMAJ2006175323916880438
   PubMed Web of Science ®Google Scholar
• WallJRGraves’ disease is a multi-system autoimmune disorder in which extra ocular muscle damage and connective tissue inflammation are variable features. “In my view”Thyroid200212353611838728
   PubMed Web of Science ®Google Scholar
• BahnRSUnderstanding the immunology of Graves’ ophthalmopathy. Is it an autoimmune disease?Endocrinol Metab Clin North Am2000292287296vi10874530
   PubMed Web of Science ®Google Scholar
• BahnRSTSH receptor expression in orbital tissue and its role in the pathogenesis of Graves’ ophthalmopathyJ Endocrinol Invest200427321622015164996
   PubMed Web of Science ®Google Scholar
• HeufelderAEDuttonCMSarkaGDonovanKABahnRSDetection of TSH receptor RNA in cultured fibroblasts from patients with Graves’ ophthalmopathy and pretibial dermopathyThyroid1993342973007509671
   PubMed Web of Science ®Google Scholar
• StadlmayrWSpitzwegCBichlmairAMHeufelderAETSH receptor transcripts and TSH receptor-like immunoreactivity in orbital and pretibial fibroblasts of patients with Graves’ ophthalmopathy and pretibial myxedemaThyroid1997713129086563
   PubMed Web of Science ®Google Scholar
• BellAGagnonAGrunderLParikhSJSmithTJSoriskyAFunctional TSH receptor in human abdominal preadipocytes and orbital fibroblastsAm J Physiol Cell Physiol20002792C335C34010912999
   PubMed Web of Science ®Google Scholar
• WallJRBernardNBoucherAPathogenesis of thyroid-associated ophthalmopathy: an autoimmune disorder of the eye muscle associated with Graves’ hyperthyroidism and Hashimoto’s thyroiditisClin Immunol Immunopathol1993681188513588
   PubMedGoogle Scholar
• KodamaKSikorskaHBandy-DafoePBaylyRWallJRDemonstration of a circulating autoantibody against a soluble eye-muscle antigen in Graves’ ophthalmopathyLancet198228312135313566184585
   PubMed Web of Science ®Google Scholar
• AtkinsonSHolcombMKendall-TaylorPOphthalmopathic immunoglobulin in patients with Graves’ ophthalmopathyLancet1984283993743766147455
   PubMed Web of Science ®Google Scholar
• FarynaMNaumanJGardasAMeasurement of autoantibodies against human eye muscle plasma membranes in Graves’ ophthalmopathyBr Med J (Clin Res Ed)19852906463191192
   Web of Science ®Google Scholar
• KahalyGMoncayoRBemetzUKrauseUBeyerJPfeifferEFEye muscle antibodies in endocrine exophthalmos. Clinical and serological observationsHorm Metab Res19892131371412744719
   PubMed Web of Science ®Google Scholar
• WuYJClarkeEMShepherdPPrevalence and significance of antibodies reactive with eye muscle membrane antigens in sera from patients with Graves’ ophthalmopathy and other thyroid and non thyroid diseasesThyroid1998821671749510126
   PubMed Web of Science ®Google Scholar
• ChangTCChangTJHuangYSHuangKMSuRJKaoSCIdentification of autoantigen recognized by autoimmune ophthalmopathy sera with immunoblotting correlated with orbital computed tomographyClin Immunol Immunopathol19926521611661395131
   PubMedGoogle Scholar
• SalviMMillerAWallJRHuman orbital tissue and thyroid membranes express a 64 kDa protein which is recognized by autoantibodies in the serum of patients with thyroid-associated ophthalmopathyFEBS Lett198823211351393366241
   PubMed Web of Science ®Google Scholar
• GunjiKDe BellisALiAWCloning and characterization of the novel thyroid and eye muscle shared protein G2s: autoantibodies against G2s are closely associated with ophthalmopathy in patients with Graves’ hyperthyroidismJ Clin Endocrinol Metab20008541641164710770210
   PubMed Web of Science ®Google Scholar
• KubotaSGunjiKStolarskiCKennerdellJSWallJRRe evaluation of the prevalences of serum autoantibodies reactive with “64-kd eye muscle proteins” in patients with thyroid-associated ophthalmopathyThyroid1998821751799510127
   PubMed Web of Science ®Google Scholar
• GunjiKKubotaSStolarskiCWengrowiczSKennerdellJSWallJRA 63 kDa skeletal muscle protein associated with eye muscle inflammation in Graves’ disease is identified as the calcium binding protein calsequestrinAutoimmunity19992911910052680
   PubMed Web of Science ®Google Scholar
• GunjiKDe BellisAKubotaSSerum antibodies against the flavoprotein subunit of succinate dehydrogenase are sensitive markers of eye muscle autoimmunity in patients with Graves’ hyperthyroidismJ Clin Endocrinol Metab19998441255126210199764
   PubMed Web of Science ®Google Scholar
• El-KaissiSFraumanAGWallJRThyroid-associated ophthalmopathy: a practical guide to classification, natural history and managementIntern Med J200434848249115317547
   PubMed Web of Science ®Google Scholar
• KasparMArchibaldCLiAWEye muscle antibodies and subtype of thyroid-associated ophthalmopathyThyroid200212318719111952037
   PubMed Web of Science ®Google Scholar
• AtabayCTyutyunikovAScaliseDSerum antibodies reactive with eye muscle membrane antigens are detected in patients with non-specific orbital inflammationOphthalmology199510211451537831030
   PubMed Web of Science ®Google Scholar
• PorterJDKhannaSKaminskiHJExtraocular muscle is defined by a fundamentally distinct gene expression profileProc Natl Acad Sci U S A20019821120621206711572940
   PubMed Web of Science ®Google Scholar
• De BellisASansonDCoronellaCSerum antibodies to collagen XIII: a further good marker of active Graves’ ophthalmopathyClin Endocrinol (Oxf)2005621242915638866
   PubMed Web of Science ®Google Scholar
• GopinathBMusselmanRBeardNAntibodies targeting the calcium binding skeletal muscle protein calsequestrin are specific markers of ophthalmopathy and sensitive indicators of ocular myopathy in patients with Graves’ diseaseClin Exp Immunol20061451566216792674
   PubMed Web of Science ®Google Scholar
• GopinathBMusselmanRAdamsCLTaniJBeardNWallJRStudy of serum antibodies against three eye muscle antigens and the connective tissue antigen collagen XIII in patients with Graves’ disease with and without ophthalmopathy: correlation with clinical featuresThyroid2006161096797417042681
   PubMed Web of Science ®Google Scholar
• Sandberg-LallMHaggPOWahlstromIPihlajaniemiTType XIII collagen is widely expressed in the adult and developing human eye and accentuated in the ciliary muscle, the optic nerve and the neural retinaExp Eye Res200070440141010865988
   PubMed Web of Science ®Google Scholar
• BartalenaLBogazziFPecoriFMartinoEGraves’ disease occurring after subacute thyroiditis: report of a case and review of the literatureThyroid1996643453488875758
   PubMed Web of Science ®Google Scholar
• IitakaMMomotaniNHisaokaTTSH receptor antibody-associated thyroid dysfunction following subacute thyroiditisClin Endocrinol (Oxf)19984844454539640411
   PubMed Web of Science ®Google Scholar
• AmatoGRotondiNSalzanoIExtraocular muscle antibodies positivity as the only serum marker of euthyroid Graves’ ophthalmopathy following subacute thyroiditis: case reportJ Clin Endocrinol Metab200085395095210720021
   PubMed Web of Science ®Google Scholar
• BednarczukTHiromatsuYInoueYYamamotoKWallJRNaumanJT-cell-mediated immunity in thyroid-associated ophthalmopathyThyroid200212320921511952041
   PubMed Web of Science ®Google Scholar
• WeetmanAPCohenSGatterKCFellsPShineBImmunohistochemical analysis of the retrobulbar tissues in Graves’ ophthalmopathyClin Exp Immunol19897522222272784734
   PubMed Web of Science ®Google Scholar
• ForsterGOttoEHansenCOchsKKahalyGAnalysis of orbital T cells in thyroid-associated ophthalmopathyClin Exp Immunol199811234274349649211
   PubMed Web of Science ®Google Scholar
• PappaALawsonJMCalderVFellsPLightmanST cells and fibroblasts in affected extraocular muscles in early and late thyroid associated ophthalmopathyBr J Ophthalmol200084551752210781517
   PubMed Web of Science ®Google Scholar
• NguyenBGopinathBTaniJWescombeLWallJRPeripheral blood T lymphocyte sensitisation against calsequestrin and flavoprotein in patients with Graves’ ophthalmopathyAutoimmunity200841537237618568642
   PubMed Web of Science ®Google Scholar
• BednarczukTGopinathBPloskiRWallJRSusceptibility genes in Graves’ ophthalmopathy: searching for a needle in a haystack?Clin Endocrinol (Oxf)200767131917521325
   PubMed Web of Science ®Google Scholar
• ThorntonJKellySPHarrisonRAEdwardsRCigarette smoking and thyroid eye disease: a systematic reviewEye20072191135114516980921
   PubMed Web of Science ®Google Scholar
• VestergaardPSmoking and thyroid disorders – a meta-analysisEur J Endocrinol2002146215316111834423
   PubMed Web of Science ®Google Scholar
• WescombeLLahootiHGopinathBWallJRThe cardiac calsequestrin gene (CASQ2) is up-regulated in the thyroid in patients with Graves’ ophthalmopathy – support for a role of autoimmunity against calsequestrin as the triggering eventClin Endocrinol2010 In Press.
   Web of Science ®Google Scholar
• DiehnJJDiehnMMarmorMFBrownPODifferential gene expression in anatomical compartments of the human eyeGenome Biol200569R7416168081
   PubMed Web of Science ®Google Scholar
• GerdingMNvan der MeerJWBroeninkMBakkerOWiersingaWMPrummelMAssociation of thyrotrophin receptor antibodies with the clinical features of Graves’ ophthalmopathyClin Endocrinol (Oxf)200052326727110718823
   PubMed Web of Science ®Google Scholar