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Review

Hematopoietic stem cells: ex-vivo expansion and therapeutic potential for myocardial ischemia

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Pages 57-68 | Published online: 30 Mar 2010

References

  • Lloyd-JonesDAdamsRCarnethonMHeart disease and stroke statistics – 2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics SubcommitteeCirculation2009119348048619171871
  • SegersVFMLeeRTStem-cell therapy for cardiac diseaseNature2008451718193794218288183
  • AssmusBHonoldJSchachingerVTranscoronary transplantation of progenitor cells after myocardial infarctionNew Engl J Med2006355121222123216990385
  • SchachingerVErbsSElsasserAIntracoronary bone marrow-derived progenitor cells in acute myocardial infarctionNew Engl J Med2006355121210122116990384
  • LaflammeMAMurryCERegenerating the heartNat Biotechnol200523784585616003373
  • MakinoSFukudaKMiyoshiSCardiomyocytes can be generated from marrow stromal cells in vitroJ Clin Invest1999103569770510074487
  • LiuYSongJALiuWXWanYChenXCHuCJGrowth and differentiation of rat bone marrow stromal cells: does 5-azacytidine trigger their cardiomyogenic differentiation?Cardiovasc Res200358246046812757880
  • MaJGeJBZhangSHTime course of myocardial stromal cell-derived factor 1 expression and beneficial effects of intravenously administered bone marrow stem cells in rats with experimental myocardial infarctionBasic Res Cardiol2005100321722315754085
  • ShakeJGGruberPJBaumgartnerWAMesenchymal stem cell implantation in a swine myocardial infarct model: Engraftment and functional effectsAnn Thorac Surg20027361919192512078791
  • LiHFanXKoviRCSpontaneous expression of embryonic factors and p53 point mutations in aged mesenchymal stem cells: A model of age-related tumorigenesis in miceCancer Res20076722108891089818006834
  • BeltramiAPBarlucchiLTorellaDAdult cardiac stem cells are multipotent and support myocardial regenerationCell2003114676377614505575
  • OhHBradfuteSBGallardoTDCardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarctionP Natl Acad Sci U S A2003100211231312318
  • CaiCLLiangXQShiYQIsl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heartDev Cell20035687788914667410
  • BuLJiangXMartin-PuigSHuman ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineagesNature2009460725111311719571884
  • DawnBSteinABUrbanekKCardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac functionP Natl Acad Sci U S A20051021037663771
  • OrlicDKajsturaJChimentiSBone marrow cells regenerate infarcted myocardiumNature2001410682970170511287958
  • DasHGeorgeJCJosephMStem cell therapy with overexpressed VEGF and PDGF genes improves cardiac function in a rat infarct modelPLoS One2009410e732519809493
  • Alvarez-DoladoMPardalRGarcia-VardugoJMFusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytesNature2003425696196897314555960
  • MurryCESoonpaaMHReineckeHHaematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarctsNature2004428698366466815034593
  • BalsamLBWagersAJChristensenJLKofdisTWeissmanILRobbinsRCHaematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardiumNature2004428698366867315034594
  • StrauerBEBrehmMZeusTRepair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humansCirculation2002106151913191812370212
  • DimmelerSZeiherAMSchneiderMDUnchain my heart: the scientific foundations of cardiac repairJ Clin Invest2005115357258315765139
  • WollertKCMeyerGPLotzJIntracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trialLancet2004364942914114815246726
  • Fernandez-AvilesFSan RomanJAGarcia-FradeJExperimental and clinical regenerative capability of human bone marrow cells after myocardial infarctionCirculation Research200495774274815358665
  • de la FuenteLMStertzerSHArgentieriJTransendocardial autologous bone marrow in chronic myocardial infarction using a helical needle catheter: 1-year follow-up in an open-label, nonrandomized, single-center pilot study (the TABMMI study)American Heart Journal2007154179e71e7717584556
  • BlankUKarlssonGKarlssonSSignaling pathways governing stem-cell fateBlood2008111249250317914027
  • Artavanis-TsakonasSRandMDLakeRJNotch signaling: cell fate control and signal integration in developmentScience1999284541577077610221902
  • KaranuFNMurdochBGallacherLThe Notch ligand Jagged-1 represents a novel growth factor of human hematopoietic stem cellsJ Exp Med200019291365137211067884
  • OhishiKVarnum-FinneyBBernsteinIDDelta-1 enhances marrow and thymus repopulating ability of human CD34(+)CD38(−) cord blood cellsJ Clin Invest200211081165117412393852
  • DelaneyCVarnum-FinneyBAoyamaKBrashem-SteinCBernsteinIDDose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cellsBlood200510682693269915976178
  • KunisatoAChibaSNakagami-YamaguchiEHES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivoBlood200310151777178312406868
  • CalviLMAdamsGBWeibrechtKWOsteoblastic cells regulate the haematopoietic stem cell nicheNature2003425696084184614574413
  • AustinTWSolarGPZieglerFCLiemLMatthewsWA role for the Wnt gene family in hematopoiesis: Expansion of multilineage progenitor cellsBlood19978910362436359160667
  • ReyaTDuncanAWAillesLA role for Wnt signalling in self-renewal of haematopoietic stem cellsNature2003423693840941412717450
  • BlankUKarlssonGMoodyJLSmad7 promotes self-renewal of hematopoietic stem cellsBlood2006108134246425416917010
  • HatzfeldJLiMLBrownELRelease of early human hematopoietic progenitors from quiescence by antisense transforming growth factor beta 1 or Rb oligonucleotidesJ Exp Med199117449259291717634
  • BhatiaMBonnetDWuDBone morphogenetic proteins regulate the developmental program of human hematopoietic stem cellsJ Exp Med199918971139114810190905
  • BhardwajGMurdochBWuDSonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulationNat Immunol20012217218011175816
  • MorrisonSJSpradlingACStem cells and niches: mechanisms that promote stem cell maintenance throughout lifeCell2008132459861118295578
  • WilsonATrumppABone-marrow haematopoietic-stem-cell nichesNat Rev Immunol2006629310616491134
  • OsawaMHanadaKHamadaHNakauchiHLong-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cellScience199627352722422458662508
  • RiegerMAHoppePSSmejkalBMEitelhuberACSchroederTHematopoietic Cytokines Can Instruct Lineage ChoiceScience2009325593721721819590005
  • TaichmanRSBlood and bone: two tissues whose fates are intertwined to create the hematopoietic stem-cell nicheBlood200510572631263915585658
  • WrightDEBowmanEPWagersAJButcherECWeissmanILHematopoietic stem cells are uniquely selective in their migratory response to chemokinesJ Exp Med200219591145115411994419
  • NagasawaTHirotaSTachibanaKDefects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1Nature199638265926356388757135
  • DistlerJHJungelAKurowska-StolarskaMNucleofection: a new, highly efficient transfection method for primary human keratinocytes*Exp Dermatol200514431532015810891
  • LatailladeJJClayDDupuyCChemokine SDF-1 enhances circulating CD34(+) cell proliferation in synergy with cytokines: possible role in progenitor survivalBlood200095375676810648383
  • LeeYGotohAKwonHJEnhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokinesBlood200299124307431712036856
  • AraiFHiraoAOhmuraMTie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow nicheCell2004118214916115260986
  • ZhangJWNiuCYeLIdentification of the haematopoietic stem cell niche and control of the niche sizeNature2003425696083684114574412
  • MaenoMMeadPEKelleyCThe role of BMP-4 and GATA-2 in the induction and differentiation of hematopoietic mesoderm in Xenopus laevisBlood1996886196519728822915
  • HirschEIglesiasAPotocnikAJHartmannUFasslerRImpaired migration but not differentiation of haematopoietic stem cells in the absence of beta1 integrinsNature199638065701711758600394
  • LevesqueJPSimmonsPJCytoskeleton and integrin-mediated adhesion signaling in human CD34+ hemopoietic progenitor cellsExp Hematol199927457958610210315
  • HiguchiAYangSTLiPTPolymeric Materials for Ex vivo Expansion of Hematopoietic Progenitor and Stem CellsPolym Rev2009493181200
  • IngberDExtracellular matrix and cell shape: potential control points for inhibition of angiogenesisJ Cell Biochem19914732362411724246
  • ChuaKNChaiCLeePCRamakrishnaSLeongKWMaoHQFunctional nanofiber scaffolds with different spacers modulate adhesion and expansion of cryopreserved umbilical cord blood hematopoietic stem/progenitor cellsExp Hematol200735577178117577926
  • McBeathRPironeDMNelsonCMBhadrirajuKChenCSCell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitmentDev Cell20046448349515068789
  • GuilakFCohenDMEstesBTGimbleJMLiedtkeWChenCSControl of stem cell fate by physical interactions with the extracellular matrixCell Stem Cell200951172619570510
  • EnglerAJSenSSweeneyHLDischerDEMatrix elasticity directs stem cell lineage specificationCell2006126467768916923388
  • WinerJPJanmeyPAMcCormickMEFunakiMBone marrow-derived human mesenchymal stem cells become quiescent on soft substrates but remain responsive to chemical or mechanical stimuliTissue Eng Part A200915114715418673086
  • SahaKKeungAJIrwinEFSubstrate modulus directs neural stem cell behaviorBiophys J20089594426443818658232
  • ChristophersonGTSongHMaoHQThe influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferationBiomaterials200930455656418977025
  • YimEKFPangSWLeongKWSynthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineageExp Cell Res200731391820182917428465
  • ArnoldMCavalcanti-AdamEAGlassRActivation of integrin function by nanopatterned adhesive interfacesChemphyschem20045338338815067875
  • KantawongFBurgessKEJayawardenaKWhole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signallingBiomaterials200930274723473119560200
  • MartinMJMuotriAGageFVarkiAHuman embryonic stem cells express an immunogenic nonhuman sialic acidNat Med200511222823215685172
  • DouayLExperimental culture conditions are critical for ex vivo expansion of hematopoietic cellsJ Hematoth Stem Cell2001103341346
  • YoshidaTHazanIZhangJThe role of the chromatin remodeler Mi-2 beta in hematopoietic stem cell self-renewal and multilineage differentiationGene Dev20082291174118918451107
  • ArakiHYoshinagaKBoccuniPZhaoYHoffmanRMahmudNChromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potentialBlood200710983570357817185465
  • FraserCCEavesCJSzilvassySJHumphriesRKExpansion In vitro of Retrovirally Marked Totipotent Hematopoietic Stem-CellsBlood1990766107110762400803
  • MillerCLEavesCJExpansion in vitro of adult murine hematopoietic stem cells with transplantable lympho-myeloid reconstituting abilityProc Natl Acad Sci U S A1997942513648136539391080
  • IscoveNNNawaKHematopoietic stem cells expand during serial transplantation in vivo without apparent exhaustionCurr Biol19977108058089368765
  • UedaTTsujiKYoshinoHExpansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptorJ Clin Invest200010571013102110749580
  • BhatiaMBonnetDKappUWangJCMurdochBDickJEQuantitative analysis reveals expansion of human hematopoietic repopulat-ing cells after short-term ex vivo cultureJ Exp Med199718646196249254660
  • GlimmHEavesCJDirect evidence for multiple self-renewal divisions of human in vivo repopulating hematopoietic cells in short-term cultureBlood19999472161216810498585
  • BorgeOJRamsfjellVVeibyOPMurphyMJJrLokSJacobsenSEThrombopoietin, but not erythropoietin promotes viability and inhibits apoptosis of multipotent murine hematopoietic progenitor cells in vitroBlood1996888285928708874182
  • CashmanJDEavesCJHuman growth factor-enhanced regeneration of transplantable human hematopoietic stem cells in nonobese diabetic/severe combined immunodeficient miceBlood19999324814879885209
  • BagleyJRosenzweigMMarksDFPykettMJExtended culture of multipotent hematopoietic progenitors without cytokine augmentation in a novel three-dimensional deviceExp Hematol199927349650410089912
  • LaIuppaJAMcAdamsTAPapoutsakisETMillerWMCulture materials affect ex vivo expansion of hematopoietic progenitor cellsJ Biomed Mater Res19973633473599260106
  • FrankeKPompeTBornhauserMWernerCEngineered matrix coatings to modulate the adhesion of CD133+ human hematopoietic progenitor cellsBiomaterials200728583684317034846
  • SagarBMRentalaSGopalPNSharmaSMukhopadhyayAFibronectin and laminin enhance engraftibility of cultured hematopoietic stem cellsBiochem Biophys Res Commun200635041000100517045241
  • JiangXSChaiCZhangYZhuoRXMaoHQLeongKWSurface-immobilization of adhesion peptides on substrate for ex vivo expansion of cryopreserved umbilical cord blood CD34(+) cellsBiomaterials200627132723273216376984
  • ChuaKNChaiCLeePCSurface-aminated electrospun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cellsBiomaterials200627366043605116854459
  • FengQChaiCJiangXSLeongKWMaoHQExpansion of engrafting human hematopoietic stem/progenitor cells in three-dimensional scaffolds with surface-immobilized fibronectinJ Biomed Mater Res A200678478179116739181
  • DasHAbdulhameedNJosephMSakthivelRMaoHQPompiliVJEx vivo nanofiber expansion and genetic modification of human cord blood-derived progenitor/stem cells enhances vasculogenesisCell Transplant200918330531819558779
  • TemplinCKotlarzDFaulhaberJEx vivo expanded hematopoietic progenitor cells improve cardiac function after myocardial infarction: role of beta-catenin transduction and cell doseJ Mol Cell Cardiol200845339440318671980
  • Hai-JiangWXin-NaDHui-JunDExpansion of hematopoietic stem/progenitor cellsAm J Hematol2008831292292618839435
  • SmithRRBarileLMessinaEMarbanEStem cells in the heart: What’s the buzz all about? Part 2: Arrhythmic risks and clinical studiesHeart Rhythm20085688088718534373
  • GeorgeJCGoldbergJJosephMTransvenous intramyocardial cellular delivery increases retention in comparison to intracoronary delivery in a porcine model of acute myocardial infarctionJ Interv Cardiol200821542443119012733
  • SanchezPLVillaASanzRPresent and future of stem cells for cardiovascular therapyAnn Med200739641242717852037
  • MathurAMartinJFStem cells and repair of the heartLancet2004364942918319215246732
  • WollertKCDrexlerHClinical applications of stem cells for the heartCirculation Research200596215116315692093