318
Views
14
CrossRef citations to date
0
Altmetric
Review

Clinical studies with oral lipid based formulations of poorly soluble compounds

, , &
Pages 591-604 | Published online: 24 Dec 2022

References

  • AcostaEKurlatDHBiscegliaMInduced electric birefringence and viscosity studies in microemulsionsColloids Surfaces A: Physicochem Eng Aspects19961061121
  • AngelucciLPetrangeliBCellettiPBioavailability of flufenamic acid in hard and soft gelatin capsulesJ Pharm Sci19766545561263104
  • ArmstrongNAJamesKCDrug release from lipid based dosage forms. IIInter J Pharm19806195204
  • Avanti® Polar Lipids, LtdHigh-dose fenretinide delivery with novel Lym-X-Sorb™ organized lipid complex [online]2006 Accessed on December 1st, 2006. http://www.avantilipids.com/LXS-DD.asp
  • AungstBJIntestinal permeation enhancersJ Pharm Sci2000894294210737905
  • BakatselouVOppenheimRCDressmanJBSolubilization and wetting effects of bile salts on the dissolution of steroidsPharm Res19918146191808607
  • BarkerSAYapSPYuenKHAn investigation into the structure and bioavailability of alpha-tocopherol dispersions in Gelucire 44/14J Contr Rel20039147788
  • BatesTRSequeiraJABioavailability of micronized griseofulvin from corn oil-in-water emulsion, aqueous suspension, and commercial tablet dosage forms in humansJ Pharm Sci19756479371151647
  • BatesTRPieniaszekHJJrSequeiraJAGastrointestinal absorption of griseofulvin from corn oil-in-water emulsions: effect of amount of corn oil ingested in manArch Dermatol19771133026843096
  • BekermanTGolenserJDombACyclosporin nanoparticulate lipospheres for oral administrationJ Pharm Sci20049312647015067702
  • BenetLThe drug efflux-metabolism alliance: biochemical aspectsAdv Drug Deliv Rev200150S3S1111576692
  • BergenholtzJRomagnoliAAWagnerNJViscosity, microstructure and interparticle potential of AOT/H2O/n-decane inverse microemulsionsLangmuir199511155970
  • BruniGGallettiFSteroidal ethers: urinary excretion of pregnane-diols in man after ingestion of quingestrone in fasting or non-fasting conditionsSteroidologia1970189935520688
  • CardielloPGMonhapholTMahanontharitAPharmacokinetics of once-daily saquinavir hard-gelatin capsules and saquinavir soft-gelatin capsules boosted with ritonavir in HIV-1-infected subjectsJAIDS200332375912640194
  • CharmanWNRoggeMCBoddyAWEffect of food and a monoglyceride emulsion formulation on danazol bioavailabilityJ Clin Pharmacol19933338168473554
  • ConstantinidesPPScalartJPFormulation and physical characterization of water-in-oil microemulsions containing long versus medium chain length glyceridesInt J Pharm19971585768
  • CornaireGWoodleyJHermannPImpact of excipients on the absorption of P-glycoprotein substrates in vitro and in vivoInt J Pharm20042781193115158955
  • de SmidtPCCampaneroMATroconizIFIntestinal absorption of penclomedine from lipid vehicles in the conscious rat: contribution of emulsification versus digestibilityInt J Pharm20042701091814726127
  • DreweJMeierRVonderscherJEnhancement of the oral absorption of cyclosporin in manBr J Clin Pharmacol1992346041633069
  • DunnCJWagstaffAJPerryCMCyclosporin: an updated review of the pharmacokinetic properties, clinical efficacy and tolerability of a microemulsion-based formulation (neoral) in organ transplantationDrugs2001611957201611708766
  • el TayarNMarkAEVallatPSolvent-dependent conformation and hydrogen-bonding capacity of cyclosporin A: evidence from partition coefficients and molecular dynamics simulationsJ Med Chem1993363757648254605
  • [FDA] Food and Drug AdministrationRitonavir prescribing information [online]2006 Accessed on December 1st, 2006. URL: http://www.fda. gov/cder/foi/label/2003/20659slr030,20945slr013_norvir_lbl.pdf
  • FischlerMFrischEPOrtengrenBPlasma concentrations after oral administration of different pharmaceutical preparations of clomethiazoleActa Pharm Suec197310483924773115
  • GaoZGChoiHGShinHJPhysicochemical characterization and evaluation of a microemulsion system for oral delivery of cyclosporin AInter J Pharm19981617586
  • GershanikTBenitaSSelf-dispersing lipid formulations for improving oral absorption of lipophilic drugsEur J Pharm Biopharm2000501798810840200
  • Gonzalez-LlavenJPalma-AguirreJAGarcia-ArreolaRComparative bioavailability evaluation of two cyclosporine oral formulations in healthy Mexican volunteersArch Med Res1999303151910573634
  • GursoyRNBenitaSSelf-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugsBiomed Pharmacother2004581738215082340
  • HargroveJTMaxsonWSWentzACAbsorption of oral progesterone is influenced by vehicle and particle sizeAm J Obstet Gynecol1989161948512801843
  • HolmbergIAknesLBerlinTAbsorption of a pharmacological dose of vitamin D3, from two different lipid vehicles in man: comparison of peanut oil and a medium chain triglycerideBiopharm Drug Dispos199011807152176898
  • HoltDWMuellerEAKovarikJMThe pharmacokinetics of Sandimmun Neoral: a new oral formulation of cyclosporineTransplant Proc199426293597940927
  • HuggerEDNovakBLBurtonPSA comparison of commonly used polyethoxylated pharmaceutical excipients on their ability to inhibit P-glycoprotein activity in vitroJ Pharm Sci2002911991200212210046
  • HumberstoneAJCharmanWNLipid-based vehicles for the oral delivery of poorly water soluble drugsAdv Drug Deliv Rev19972510328
  • HuntJNKnoxMTA relation between the chain length of fatty acids and the slowing of gastric emptyingJ Physiol1968194327365639357
  • JuliantoTYuenKHNoorAMImproved bioavailability of vitamin E with a self emulsifying formulationInt J Pharm200020053710845685
  • KarpfDMHolmRKristensenHGInfluence of the type of surfactant and the degree of dispersion on the lymphatic transport of halofantrine in conscious ratsPharm Res2004814131815359576
  • KhooSMHumberstoneAJPorterCJHEdwardsGACharmanWNFormulation design and bioavailability assessment of lipidic self-emulsifying formulations of halofantrineInter J Pharm199816715564
  • KhossraviMKaoYHMrsnyRJAnalysis methods of polysorbate 20: A new method to assess the stability of polysorbate 20 and established methods that may overlook degraded polysorbate 20Pharm Res20025634912069166
  • KlyashchitskyBAOwenAJDrug delivery systems for cyclosporine: achievements and complicationsJ Drug Target199854434589783676
  • KovarikJMMuellerEAJohnstonABioequivalence of soft gelatin capsules and oral solution of a new cyclosporine formulationPharmacotherapy199313613178302687
  • KovarikJMMuellerEAvan BreeJBReduced inter- and intraindividual variability in cyclosporine pharmacokinetics from a microemulsion formulationJ Pharm Sci19948344468207699
  • KurowskiMSternfieldTSawyerAPharmacokinetic and tolerability profile of twice daily saquinavir hard gelatin capsules and saquinavir soft gelatin capsules boosted with ritonavir in healthy volunteersHIV Medicine200349410012702129
  • LadasSDIsaacsPEMurphyGMComparison of the effects of medium and long chain triglyceride containing liquid meals on gall bladder and small intestinal function in normal manGut1994440511
  • LepageGYesairDWRoncoNEffect of an organized lipid matrix on lipid absorption and clinical outcomes in patients with cystic fibrosisJ Pediatr20021411788512183711
  • LarsenAJanninVMullertzAPharmaceutical surfacts in biorelevant media: impact on lipolysis and solubility of a poorly soluble model compound: danazol2006Proceedings 5th World Meeting in Pharmaceutics, Biopharmaceutics and Pharmaceutical TechnologyMarch 27–30Geneva, Switzerland
  • LawrenceMJReesGDMicroemulsion-based media as novel drug delivery systemsAdv Drug Deliv Rev2000458912111104900
  • MacherasPEReppasCIStudies on drug-milk freeze-dried formulations. I: Bioavailability of sulfamethizole and dicumarol formulationsJ Pharm Sci1986a7569262428969
  • MacherasPEReppasCIStudies on freeze-dried drug-milk formulations. II: Effect of regenerated fluid volume on nitrofurantoin bioavailabilityJ Pharm Sci1986b751145503559923
  • Martin-FacklamMBurhenneJDingRDose-dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor ELBr J Clin Pharmacol2002535768112047481
  • MalingreMMSchellensJHVan TellingenOThe co-solvent Cremophor EL limits absorption of orally administered paclitaxel in cancer patientsBr J Cancer2001851472711720431
  • MuellerEAKovarikJMvan BreeJBImproved dose linearity of cyclosporine pharmacokinetics from a microemulsion formulationPharm Res1994a1130148165192
  • MuellerEAKovarikJMvan BreeJBInfluence of a fat-rich meal on the pharmacokinetics of a new oral formulation of cyclosporine in a crossover comparison with the market formulationPharm Res1994b1115158140046
  • NielsenFSGibaultELjusberg-WahrerHCharacterization of prototype self-nanoemulsifying formulations of lipophilic compoundsJ. Pharm Sci2007968769217279513
  • OdebergJMKaufmannPKroonKGLipid drug delivery and rational formulation design for lipophilic drugs with low oral bioavailability, applied to cyclosporineEur J Pharm Sci2003203758214659481
  • PollardSNashanBJohnstonAA pharmacokinetic and clinical review of the potential clinical impact of using different formulations of cyclosporin AClin Ther20032516546912860490
  • PorterCJCharmanWNUptake of drugs into the intestinal lymphatics after oral administrationAdv Drug Deliv Rev1997257189
  • PorterCJCharmanWNIn vitro assessment of oral lipid based formulationsAdv Drug Deliv Rev200150S127S14711576699
  • PorterCJKaukonenAMBoydBJSusceptibility to lipase-Mediated Digestion Reduces the Oral Bioavailability of Danazol After Administration as a Medium-Chain Lipid-Based Microemulsion FormulationPharm Res2004814051215359575
  • PoutonCWFormulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification systemEur J Pharm Sci2006292788716815001
  • PostolachePPetrescuODorneanuVCyclosporine bioavailability of two physically different oral formulationsEur Rev Med Pharmacol Sci200261273112776806
  • PoutonCWFormulation of self-emulsifying drug delivery systemsAdv Drug Del Rev1997254758
  • PoutonCWLipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and ‘self-microemulsifying’ drug delivery systemsEur J Pharm Sci200011S93S9811033431
  • RegeBDKaoJPPolliJEEffects of nonionic surfactants on membrane transporters in Caco-2 cell monolayersEur J Pharm Sci2002162374612208453
  • RegevOEzrahiSAserinAA study of the microstructure of a four-component nonionic microemulsion by cryo-TEM, NMR, SAXS and SANSLangmuir19961266874
  • RitschelWAMicroemulsions for improved peptide absorption from the gastrointestinal tractMethods Find Exp Clin Pharmac19961320520
  • Roche Laboratories, Inc.Fortovase® prescribing information [online]2004a Accessed on December 1, 2006. URL: http://www.rocheusa. com/products/fortovase/pi.pdf
  • RolanPEMercerAJWeatherleyBCExamination of some factors responsible for a food-induced increase in absorption of atova-quoneBr J Clin Pharmacol19943713208148213
  • SchmidtLEDalhoffKFood-drug interactionsDrugs200262148150212093316
  • SeeballuckFAshfordMBO’DriscollCMThe effects of pluronics block copolymers and cremophor EL on intestinal lipoprotein processing and the potential link with P-glycoprotein in Caco-2 cellsPharm Res20032010859212880295
  • ShonoYNishiharaHMatsudaYModulation of intestinal P-glycoprotein function by cremophor EL and other surfactants by an in vitro diffusion chamber method using the isolated rat intestinal membranesJ Pharm Sci2004938778514999725
  • SinghBNEffects of food on clinical pharmacokineticsClin Pharmacokinet1999372135510511919
  • StrickleyRGSolubilizing excipients in oral and injectable formulationsPharm Res2004212013015032302
  • VinsonPKSheehanJGMillerWGViewing microemulsions with freeze-fracture transmission electron microscopyJ Phys Chem19919525462550
  • WeisMMortensenSARassingMRBioavailability of four oral coenzyme Q10 formulations in healthy volunteersMol Aspects Med199415s273s2807752839
  • YamahiraYNoguchiTNoguchiTAbsorption of diazepam from a lipid-containing oral dosage formChem Pharm Bull (Tokyo)19792711908498373
  • YapSPYuenKHInfluence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulationsInt J Pharm2004281677815288344