123
Views
27
CrossRef citations to date
0
Altmetric
Review

Serotonin receptor modulators in the treatment of irritable bowel syndrome

&
Pages 41-48 | Published online: 08 Feb 2008

References

  • American Gastroenterological AssociationThe burden of gastrointestinal diseases2002AGA Press
  • AtkinsonWLockhartSWhorwellPJAltered 5-hydroxytryptamine signaling in patients with constipation- and diarrhea-predominant irritable bowel syndromeGastroenterology2006130344316401466
  • AviganMJusticeRMackeyACRe: Brandt et al An evidence-based approach to the management of irritable bowel syndrome in North AmericaAm J Gastroenterol200398210514499800
  • BakerDERationale for using serotonergic agents to treat irritable bowel syndromeAm J Health-syst Pharm2005627001315790796
  • BanhHLMacLeanCToppTThe use of tegaserod in critically ill patients with impaired gastric motilityClinical Pharmacology and Therapeutics200577583615961989
  • BradetteMMoennikesHCarterFCilansetron in irritable bowel syndrome with diarrhea predominance (IBS-D): efficacy and safety in a 6 month global studyGastroenterology2004126A42
  • BrinkerADMackeyACPrizontRTegaserod and ischemic colitisNew England Journal of Medicine20043511361415385670
  • CamilleriMChoiMGReview article: irritable bowel syndromeAliment Pharmacol Ther1997113159042970
  • CamilleriMNorthcuttARKongSEfficacy and safety of alosetron in women with irritable bowel syndrome: a randomised, placebo-controlled trialLancet200035510354010744088
  • CamilleriMReview article: tegaserodAlimentary Pharmacology and Therapeutics2001152778911207504
  • CamilleriMCheyWYMayerEAA randomized controlled clinical trial of the serotonin type 3 receptor antagonist alosetron in women with diarrhea-predominant irritable bowel syndromeArchives of Internal Medicine200116117334011485506
  • CamilleriMHeadingRCThompsonWGClinical perspectives, mechanisms, diagnosis and management of irritable bowel syndromeAlimentary Pharmacology and Therapeutics20021614073012182741
  • CamilleriMTreating irritable bowel syndrome: overview, perspective and future therapiesBritish Journal of Pharmacology200414112374815037521
  • CamilleriMMcKinzieSFoxJEffect of renzapride on transit in constipation-predominant irritable bowel syndromeClinical Gastroenterology and Hepatology2004289590415476153
  • ChenJJLiZPanHMaintance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: abnormal intestinal motility and the expression of cation transportersJ Neurosci20012163486111487658
  • CheyWDCheyWYHeathATLong-term safety and efficacy of alosetron in women with severe diarrhea-predominant irritable bowel syndromeAmerican Journal of Gastroenterology200499219515555002
  • CheyWDReview article: tegaserod – the global experienceAlimentary Pharmacology and Therapeutics200420Suppl 7151915521850
  • ClemensCHSamsomMVan BergeEffect of alosetron on left colonic motility in non-constipated patients with irritable bowel syndrome and healthy volunteersAlimentary Pharmacology and Therapeutics200216993100211966509
  • CoffinBFarmachidiJPRueeggPTegaserod, a 5-HT4 receptor partial agonist, decreases sensitivity to rectal distension in healthy subjectsAlimentary Pharmacology and Therapeutics2003175778512622767
  • CoremansGClouseRECarterFCilansetron, a novel 5-HT3 antagonist, demonstrated efficacy in males with irritable bowel syndrome with diarrhea predominance (IBS-D)Gastroenterology2004126Suppl 2A643 Abstract
  • CreedFFernandesLGuthrieENorth of England IBS Research Group. The cost-effectiveness of psychotherapy and paroxetine for severe irritable bowel syndromeGastroenterology200312430312557136
  • CremoniniFDelgado-ArosSCamilleriMEfficacy of alosetron in irritable bowel syndrome: a meta-analysis of randomized controlled trialsNeurogastroenterology and Motility200315798612588472
  • CremoniniFDelgadoArosTalleyNJFunctional dyspepsia: drugs for new (and old) therapeutic targets. Best Practice and Research in ClinicalGastroenterology20041871733
  • DegenLMatzingerDMerzMTegaserod, a 5-HT4 receptor partial agonist, accelerates gastric emptying and gastrointestinal transit in healthy male subjectsAliment Pharmacol Ther20011517455111683688
  • DrossmanDACorazziariETalleyNJRome II. The functional gastrointestinal disorders. Diagnosis, pathophysiology and treatment: A multinational consensus2000Degnon Associates
  • DelvauxMLouvelDMametJPEffect of alosetron on responses to colonic distension in patients with irritable bowel syndromeAlimentary Pharmacology and Therapeutics199812849559768527
  • DiBaiseJKTegaserod-associated ischemic colitisPharmacotherapy200525620515977922
  • DrossmanDACamilleriMMayerEAAGA technical review on irritable bowel syndromeGastroenterology200212321083112454866
  • EvansBWClarkWKMooreDJTegaserod for the treatment of irritable bowel syndromeCochrane Database of Systematic Reviews20041CD003960
  • FisherRSThistleJLemboATegaserod does not alter fasting or meal-induced biliary tract motilityAmerican Journal of Gastroenterology1999991342915233676
  • FriedMBeglingerCBobaljNGTegaSwiss Study Group. Tegaserod is safe, well tolerated and effective in the treatment of patients with non-diarrhoea irritable bowel syndromeEuropean Journal of Gastroenterology and Hepatology200517421715756094
  • GershonMDReview article: serotonin receptors and transporters - roles in normal and abnormal gastrointestinal motilityAlimentary Pharmacology and Therapeutics200420Suppl 731415521849
  • GershonMDNerves, refl exes, and the enteric nervous systemJ Clin Gastroenterol200539S1849315798484
  • GorardDALibbyGWFarthingMJGInfl uence of antidepressants on whole gut and orocaecal transit time in health and irritable bowel syndromeAliment Pharmacol Ther19948159668038347
  • GoyalRKHiranoIMechanisms of disease: the enteric nervous systemNEJM19963341106158598871
  • GriderJRKuemmerleJFJinJG5-HT released by mucosal stimuli initiates peristalsis by activating 5-HT4/ 5-HT1p receptors on sensory CGRP neuronsAm J Physiol1996270G778828967488
  • HahnBAYanSStrasselsSImpact of irritable bowel syndrome on quality of life and resource use in the United States and United KingdomDigestion19996077819892803
  • HoughtonLAFosterJMWhorwellPJAlosetron, a 5-HT3 receptor antagonist, delays colonic transit in patients with irritable bowel syndrome and healthy volunteersAlimentary Pharmacology and Therapeutics2000147758210848662
  • IrvineEJReview: Tegaserod prompts global relief of symptoms in irritable bowel syndromeACP Journal Club20041414415341464
  • IshiguchiTItohHIchinoseMGastrointestinal motility and the brain-gut axisDig Endosc200415816
  • JohansonJFReview article: tegaserod for chronic constipationAlimentary Pharmacology and Therapeutics200420Suppl 720415521851
  • JonesRHHoltmannGRodrigoLAlosetron relieves pain and improves bowel function compared with mebeverine in female nonconstipated irritable bowel syndrome patientsAlimentary Pharmacology and Therapeutics19991314192710571597
  • KammMAMuller-LissnerSTalleyNJTegaserod for the treatment of chronic constipation: a randomized, double-blind, placebo-controlled multinational studyAmerican Journal of Gastroenterology20051003627215667494
  • KawanoKMoriTFuLComparison between partial agonist (ME3412) and antagonist (alosetron) of 5-hydroxytryptamine 3 receptor on gastrointestinal functionNeurogastroenterology and Motility20051729030115787949
  • KellowJLeeOYChangFYAn Asia-Pacific, double blind, placebo controlled, randomised study to evaluate the efficacy, safety, and tolerability of tegaserod in patients with irritable bowel syndromeGut200352671612692051
  • KhoshooVArmsteadCLandryLEffect of a laxative with and without tegaserod in adolescents with constipation predominant irritable bowel syndromeAlimentary Pharmacology and Therapeutics200623191616393297
  • KilkensTOCHonigANieuwenhovenMAVAcute tryptophan depletion affects brain-gut responses in irritable bowel syndrome patients and controls2004
  • KozlowskiCMGreenAGrundyDThe 5-HT(3) receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinal c-fos expression in the anaesthetised ratGut2000464748010716675
  • KuikenSDTytgatGNBoeckxstaensGEThe selective serotonin reuptake inhibitor fl uoxetine does not change rectal sensitivity and symptoms in patients with irritable bowel syndrome: a double blind, randomized, placebo-controlled studyClinical Gastroenterology and Hepatology200312192815017494
  • LacknerJMGudleskiGDZackMMMeasuring health-related quality of life in patients with irritable bowel syndrome: Can less be more?Psychosomatic Medicine2006683122016554399
  • LemboTWrightRABagbyBLotronex Investigator TeamAlosetron controls bowel urgency and provides global symptom improvement in women with diarrhea-predominant irritable bowel syndromeAmerican Journal of Gastroenterology20019626627011569692
  • Lesbros-PantoflickovaDMichettiPFriedMMeta-analysis: The treatment of irritable bowel syndromeAlimentary Pharmacology and Therapeutics20042012536915606387
  • LevyRLVon KorffMRWhiteheadWECosts of care for irritable bowel syndrome patients in a health maintenance organizationAm J Gastroenterol2001963122911721759
  • MayerEABermanSDerbyshireSWThe effect of the 5-HT3 receptor antagonist, alosetron, on brain responses to visceral stimulation in irritable bowel syndrome patientsAlimentary Pharmacology and Therapeutics20021613576612144587
  • MorganrothJRueggPCDunger-BaldaufCTegaserod, a 5-hydroxytryptamine type 4 receptor partial agonist, is devoid of electrocardiographic effectsAmerican Journal of Gastroenterology2002972321712358251
  • Muller-LissnerSAFumagalliIBardhanKDTegaserod, a 5-HT(4) receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipationAlimentary Pharmacology and Therapeutics20011516556611564007
  • Muller-LissnerSHoltmannGRueeggPTegaserod is effective in the initial and retreatment of irritable bowel syndrome with constipationAlimentary Pharmacology and Therapeutics200521112015644040
  • NovickJMinerPKrauseRA randomized, double-blind, placebo-controlled trial of tegaserod in female patients suffering from irritable bowel syndrome with constipationAlimentary Pharmacology and Therapeutics20021618778812390096
  • NyhlinHBangCElsborgLA double-blind, placebo-controlled, randomized study to evaluate the efficacy, safety and tolerability of tegaserod in patients with irritable bowel syndromeScandinavian Journal of Gastroenterology2004391192615000272
  • PratherCMCamilleriMZinsmeisterARTegaserod accelerates orocecal transit in patients with constipation-predominant irritable bowel syndromeGastroenterology2000118463810702196
  • ReillyMCBarghoutVMcBurneyCREffect of tegaserod on work and daily activity in irritable bowel syndrome with constipationAlimentary Pharmacology and Therapeutics2005223738016128674
  • SandlerRSEverhartJEDonowitzMThe burden of selected digestive diseases in the United StatesGastroenterology200212215001111984534
  • SchoenfeldPReview article: the safety profile of tegaserodAlimentary Pharmacology and Therapeutics200420Suppl 7253015521852
  • SmithDGBarghoutVKahlerKHTegaserod treatment for IBS: a model of indirect costsAmerican Journal of Managed Care2005111 SupplS435015926763
  • TabasGBeavesMWangJParoxetine to treat irritable bowel syndrome not responding to high-fiber diet: a double-blind, placebo-controlled trialAmerican Journal of Gastroenterology2004999142015128360
  • TackJBroekaertDFischlerBA controlled cross-over study of the selective serotonin reuptake inhibitor citalopram in irritable bowel syndromeGut200655109510316401691
  • TalleyNJGabrielSEHarmsenWSMedical costs in community subjects with irritable bowel syndromeGastroenterology19951091736417498636
  • TalleyNJSerotonergic neuroenteric modulatorsLancet20013582061811755632
  • TalleyNJPharmacologic therapy for the irritable bowel syndromeAmerican Journal of Gastroenterology200398750812738451
  • TalleyNJAntidepressants in IBS: are we deluding ourselves?Am J Gastroenterol20049992115128361
  • TraynorKAlosetron use drops dramatically with risk managementAmerican Journal of Health-System Pharmacy20046112101215259746
  • VahediHMeratSRashidioonAThe effect of fl uoxetine in patients with pain and constipation-predominant irritable bowel syndrome: a double-blind randomized-controlled studyAlimentary Pharmacology and Therapeutics200522381516128675
  • ViramontesBECamilleriMMcKinzieSGender-related differences in slowing colonic transit by a 5-HT3 antagonist in subjects with diarrhea-predominant irritable bowel syndromeAmerican Journal of Gastroenterology2001962671611569693
  • WhiteheadWEBurnettCKCookEWImpact of irritable bowel syndrome on quality of lifeDig Dis Sci1996412248538943980
  • WolfeSGCheyWYWashingtonMKTolerability and safety of alosetron during long-term administration in female and male irritable bowel syndrome patientsAmerican Journal of Gastroenterology2001968031111280555