References
- ArnesenERefsumHBønaaKHSerum total homocysteine and coronary heart diseaseInt J Epidemiol19952470498550266
- BellamyMFMcDowellIFRamseyMWHyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in healthy adultsCirculation1998981848529799203
- BonaaKHNiolstadIUelandPMHomocysteine lowering and cardiovascular events after acute myocardial infarctionN Engl J Med200635415788816531614
- BostomAGLathropLHyperhomocysteinemia in end-stage renal disease: prevalence, etiology, and potential relationship to arteriosclerotic outcomesKidney Int19975210209211341
- BostomAGSilbershatzHRosenbergIHNonfasting plasma total homocysteine levels and all-cause and cardiovascular disease mortality in elderly Framingham men and womenArch Intern Med199915910778010335684
- BotsMLLaunerLJLindemansJHomocysteine and short-term risk of myocardial infarction and stroke in the elderly: the Rotterdam StudyArch Intern Med199915938449892328
- BousheyCJBeresfordSAAOmennGSA quantitative assessment of plasma homocysteine as a risk factor for vascular disease: probable benefits of increasing folic acid intakesJAMA19952741049577563456
- ChristenWGAjaniUAGlynnRJBlood levels of homocysteine and increased risks of cardiovascular disease–causal or casual?Arch Intern Med20001604223410695683
- CookJWMalinowMRMonetaGLNeointimal hyperplasia in baloon-injured rat carotid arteries: the influence of hyperhomocysteinemiaJ Vasc Surg2002351586511802148
- EvansRWShatenBJHempelJDHomocyst(e)ine and risk of cardiovascular disease in the Multiple Risk Factor Intervention TrialArterioscler Thromb Vasc Biol1997171947539351358
- FolsomARNietoFJMcGovernPGProspective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins: the Atherosclerosis Risk in Communities (ARIC) studyCirculation199898204109697819
- GilesWHCroftJBGreenlundKJTotal homocyst(e)ine concentration and the likelihood of nonfatal stroke: results from the third National Health and Nutrition Examination Survey, 1988–1994Stroke199829247379836753
- GoyettePSumnerJSMilosRHuman methylenetetrahydrofolate reductase: isolation of cDNA mapping and mutation identificationNat Genet199471952007920641
- HaydenMRTyagiSCHomocysteine and reactive oxygen species in metabolic syndrome, type 2 diabetes mellitus, and atherosleropathy: the pleiotropic effects of folate supplementationNutr J2004342715134582
- HankeyGJEikelboomJWHomocysteine and vascular diseaseLancet19993544071310437885
- HofmannMALallaELuYHyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine modelJ Clin Invest20011076758311254667
- Homocysteine Lowering Trialists’ CollaborationDose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trialsAm J Clin Nutr20028280612
- KangSSZhouJWongPWKIntermediate homocysteinemia: a thermolabile variant of methylentethrahydrofolate reductaseAm J Hum Genet198843414213177384
- KangSSWongPWKSusmanoAThermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronaru artery diseaseAm J Hum Gen19914853645
- KarkJDSelhubJBostomAPlasma homocysteine and all-cause mortality in diabetesLancet19993531936710371576
- LauricellaAMQuintanaICastanonMInfluence of homocysteine on fibrin network lysisBlood Coagul Fibrinolysis200617181616575255
- LiemAReynierse-BuitenwerfGHZwindermanAHSecondary prevention with folic acid: effects on clinical outcomesJ Am Coll Cardiol20034121051312821232
- McCullyKSVascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosisAm J Pathol196956111285792556
- MoritaHKuriharaHYoshidaSDiet-induced hyperhomocysteinemia exacerbates neointima formation in rat carotid arteries after baloon injuryCirculation2001103133911136698
- MoustaphaANasoANahlawiMProspective study of hyperhomocysteinemia as an adverse cardiovascular risk factor in end-stage renal diseaseCirculation199897138419445164
- NygårdONordrehaugJERefsumHPlasma homocysteine levels and mortality in patients with coronary artery diseaseN Engl J Med199733723069227928
- PerryIJRefsumHMorrisRWProspective study of serum total homocysteine concentration and risk of stroke in middle-aged British menLancet1995346139587475822
- PfanzaglBTriblFKollerEHomocysteine strongly enhances metal-catalyzed LDL oxidation in the presence of cystine and cysteineAtherosclerosis2003168394812732385
- RefsumHFiskerstrandTGuttormsenABAssessment of homocysteine statusJ Inher Metab Dis199720286949211200
- RefsumHUelandPMNygardOHomocysteine and cardiovascular diseaseAnn Rev Med19984931629509248
- RefsumHSmithADUelandPMFacts and recommendations about total homocysteine determinations: an expert opinionClin Chem20045033214709635
- RidkerPMMansonJEBuringJEHomocysteine and risk of cardiovascular disease among postmenopausal womenJAMA199928118172110340369
- RosenblattDSCooperBAInherited disorders of vitamin B12 utilizationBioessays19901233142203337
- SchneiderJAReesDCLiuYTWorldwide distribution of a common methylenetetrahydrofolate reductase mutationAm J Hum Genet1998621258609545406
- StampferMJMalinowMRWillettWCA prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physiciansJAMA1992268877811640615
- StehouwerCDAGallMAHougaardPPlasma homocysteine concentration predicts mortality in noninsulin-dependent diabetic patients with and without albuminuriaKidney Int199955308149893141
- StehouwerCDAWeijenbergMPvan den BergMSerum homocysteine and risk of coronary heart disease and cerebrovascular disease in elderly men: a 10-year follow-upArterioscler Thromb Vasc Biol19981818959019848881
- TaylorLMJMonetaGLSextonGJProspective blinded study of the relationship between plasma homocysteine and progression of symptomatic peripheral arterial diseaseJ Vasc Surg1999298199925456
- The Heart Outcomes Prevention Evaluation (HOPE) 2 InvestigatorsHomocysteine lowering with folic acid and B vitamins in vascular diseaseN Engl J Med200635415677716531613
- The Homocysteine Studies CollaborationHomocysteine and risk of ischemic heart disease and stroke. A meta-analysisJAMA200228820152212387654
- TooleJFMalinowMRChamblessLELowering homocysteine in patients with ischemic stroke to prevent recurrent stoke, myocardial infarction, and death: the Vitamin Intervention for Stoke Prevention (VISP) randomized controlled trialJAMA20042915657514762035
- UbbinkJBFehilyAMPickeringJHomocysteine and ischaemic heart disease in the Caerphilly cohortAtherosclerosis1998140349569862278
- UelandPMHomocysteine species as components of plasma redox thiol statusClin Chem19954134027882507
- UelandPMRefsumHPlasma homocysteine, a risk factor for vascular disease: plasma levels in health, disease and drug therapyJ Lab Clin Med19891144735012681479
- UelandPMRefsumHBeresfordSAAThe controversy over homocysteine and cardiovascular riskAm J Clin Nutr2000723243210919921
- UndasAWilliamsEBButenasSHomocysteine inhibits inactivation of facot Va by Activated Protein CJ Biol Chem200127643899711083858
- UngvariZSarkadi-NagyEBagiZSimulataneously increased TxA(2) activity in isolated arterioles and platelets of rats with hyperhomocysteinemiaAther Thromb Vasc Biol20002012038
- WaldDSLawMMorrisJKHomocysteine and cardiovascular disease: evidence on casuality from a meta-analysisBMJ20023251202912446535
- WaldDSMorrisJKLawMFolic acid, homocysteine, and cardiovascular disease: judging causality in the face of inconclusive trial evidenceBMJ20063331114717124224
- WaldNJWattHCLawMRHomocysteine and ischemic heart disease. Results of a prospective study with implications regarding preventionArch Intern Med199815886279570171
- WeisbergITranPChristensenBA second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activityMol Genet Metab199864169729719624
- WelchGNLoscalzoJHomocysteine and atherothrombosisN Engl J Med19983381042509535670
- WilckenDEWilckenBThe pathogenesis of coronary artery disease. A possible role for methionine metabolismJ Clin Invest197657107982947949
- WooKSChookPLolinYIHyperhomocyst(e)inemia is a risk factor for arterial endothelial dysfunctionin humansCirculation199796254249355891