Apolipoproteins A-I and B: biosynthesis, role in the development of atherosclerosis and targets for intervention against cardiovascular disease

References

• AdeliKMacriJMohammadiAApolipoprotein B is intracellularly associated with an ER-60 protease homologue in HepG2 cellsJ Biol Chem199727222489949278400
   PubMed Web of Science ®Google Scholar
• AdielsMBorenJCaslakeMJOverproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemiaArterioscler Thromb Vasc Biol2005a
   PubMed Web of Science ®Google Scholar
• AdielsMOlofssonSOTaskinenMRDiabetic dyslipidaemiaCurr Opin Lipidol2006172384616680028
   PubMed Web of Science ®Google Scholar
• AdielsMPackardCCaslakeMJA new combined multicompartmental model for apolipoprotein B-100 and triglyceride metabolism in VLDL subfractionsJ Lipid Res2005b46586715489544
   PubMed Web of Science ®Google Scholar
• AhnerABrodskyJLCheckpoints in ER-associated degradation: excuse me which way to the proteasome?Trends Cell Biol200414474815350974
   PubMed Web of Science ®Google Scholar
• AnderssonLBostromPEricsonJPLD1 and ERK2 regulate cytosolic lipid droplet formationJ Cell Sci200611922465716723731
   PubMed Web of Science ®Google Scholar
• AspLMagnussonBRutbergMRole of ADP ribosylation factor 1 in the assembly and secretion of ApoB-100-containing lipoproteinsArterioscler Thromb Vasc Biol2005255667015618550
   PubMed Web of Science ®Google Scholar
• BaldanAPeiLLeeRImpaired development of atherosclerosis in hyperlipidemic Ldlr-/- and ApoE-/- mice transplanted with Abcg1-/- bone marrowArterioscler Thromb Vasc Biol2006a262301716888235
   PubMed Web of Science ®Google Scholar
• BaldanATarrPLeeRATP-binding cassette transporter G1 and lipid homeostasisCurr Opin Lipidol2006b172273216680026
   PubMed Web of Science ®Google Scholar
• BarterPJRyeKAThe rationale for using apoA-I as a clinical marker of cardiovascular riskJ Intern Med20062594475416629850
   PubMed Web of Science ®Google Scholar
• BodziochMOrsoEKluckenJThe gene encoding ATP-binding cassette transporter 1 is mutated in Tangier diseaseNat Genet1999223475110431237
   PubMed Web of Science ®Google Scholar
• BorenJEkstromUAgrenBThe molecular mechanism for the genetic disorder familial defective apolipoprotein B100J Biol Chem2001a2769214811115503
   PubMed Web of Science ®Google Scholar
• BorenJLeeIZhuWIdentification of the low density lipoprotein receptor-binding site in apolipoprotein B100 and the modulation of its binding activity by the carboxyl terminus in familial defective apo-B100J Clin Invest1998a1011084939486979
   PubMed Web of Science ®Google Scholar
• BorenJLookeneAMakoveichukEBinding of low density lipoproteins to lipoprotein lipase is dependent on lipids but not on apolipoprotein BJ Biol Chem2001b276269162211331277
   PubMed Web of Science ®Google Scholar
• BorenJOlinKLeeIIdentification of the principal proteoglycan-binding site in LDL A single-point mutation in apo-B100 severely affects proteoglycan interaction without affecting LDL receptor bindingJ Clin Invest1998b1012658649637699
   PubMed Web of Science ®Google Scholar
• BostromPRutbergMEricssonJCytosolic lipid droplets increase in size by microtubule-dependent complex formationArterioscler Thromb Vasc Biol20052519455116051877
   PubMed Web of Science ®Google Scholar
• BrasaemleDLDoliosGShapiroLProteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytesJ Biol Chem2004279468354215337753
   PubMed Web of Science ®Google Scholar
• Brooks-WilsonAMMarcilSMCleeMutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiencyNat Genet1999223364510431236
   PubMed Web of Science ®Google Scholar
• CamejoGLopezAVegasHThe participation of aortic proteins in the formation of complexes between low density lipoproteins and intima-media extractsAtherosclerosis19752177911131302
   PubMed Web of Science ®Google Scholar
• CamejoGOlofssonS-OLopezFIdentification of apo B-100 segments mediating the interaction of low density lipoproteins with arterial proteoglycansArteriosclerosis19888368773395272
   PubMedGoogle Scholar
• ChattertonJEPhillipsMLCurtissLKImmunoelectron microscopy of low density lipoproteins yields a ribbon and bow model for the conformation of apolipoprotein B on the lipoprotein surfaceJ Lipid Res1995362027378558090
   PubMed Web of Science ®Google Scholar
• ClearfieldMBThe national cholesterol education program adult treatment panel ill guidelinesJ Am Osteopath Assoc2003103S1512572622
   PubMedGoogle Scholar
• ConroyRMPyoralaKFitzgeraldAPEstimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE projectJ Eur Heart2003249871003
   PubMed Web of Science ®Google Scholar
• DashtiNGandhiMLiuXThe N-terminal 1000 residues of apolipoprotein B associate with microsomal triglyceride transfer protein to create a lipid transfer pocket required for lipoprotein assemblyBiochemistry20024169788712033930
   PubMed Web of Science ®Google Scholar
• DavidsonNOShelnessGSApolipoprotein B: mRNA editing lipoprotein assembly and presecretory degradationAnn Rev Nutr2000201699310940331
   PubMed Web of Science ®Google Scholar
• DenkeMAWeighing in before the fight: low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol versus apolipoprotein B as the best predictor for coronary heart disease and the best measure of therapyCirculation200511233687016316961
   PubMed Web of Science ®Google Scholar
• EllgaardLHeleniusAER quality control: towards an understanding at the molecular levelCurr Opin Cell Biol200113431711454449
   PubMed Web of Science ®Google Scholar
• EllgaardLHeleniusAQuality control in the endoplasmic reticulumNat Rev Mol Cell Biol200341819112612637
   PubMed Web of Science ®Google Scholar
• EllgaardLMolinariMHeleniusASetting the standards:Quality control in the secretory pathwayScience19992861882810583943
   PubMed Web of Science ®Google Scholar
• FisherEAGinsbergHNComplexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteinsJ Biol Chem2002277173778012006608
   PubMed Web of Science ®Google Scholar
• FisherEAPanMChenXThe triple threat to nascent apolipoprotein B Evidence for multiple distinct degradative pathwaysJ Biol Chem2001276278556311285257
   PubMed Web of Science ®Google Scholar
• FloodCGustafssonMPitasREMolecular mechanism for changes in proteoglycan binding on compositional changes of the core and the surface of low-density lipoprotein-containing human apolipoprotein B100Arterioscler Thromb Vasc Biol2004245647014726411
   PubMed Web of Science ®Google Scholar
• FrancisMCFrohlichJJCoronary artery disease in patients at low risk – apolipoprotein AI as an independent risk factorAtherosclerosis20011551657011223438
   PubMed Web of Science ®Google Scholar
• GelissenICHarrisMRyeKAABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-IArterioscler Thromb Vasc Biol2006265344016357317
   PubMed Web of Science ®Google Scholar
• GenestJFrohlichJFodorGRecommendations for the management of dyslipidemia and the prevention of cardiovascular disease: summary of the 2003 updateCmaj2003169921414581310
   PubMed Web of Science ®Google Scholar
• GibbonsGFIslamKPeaseRJMobilisation of triacylglycerol stores BiochimBiophys Acta200014833757
   PubMed Web of Science ®Google Scholar
• Gillian-DanielDLBatesPWTebonAEndoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein BProc Natl Acad Sci USA2002994337211904390
   PubMed Web of Science ®Google Scholar
• GottoAMWhitneyEJrSteinEARelation between baseline and on-treatment lipid parameters and first acute major coronary events in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS)Circulation20001014778410662743
   PubMed Web of Science ®Google Scholar
• GrundySMLow-density lipoprotein non-high-density lipoprotein and apolipoprotein B as targets of lipid-lowering therapyCirculation20021062526912427645
   PubMed Web of Science ®Google Scholar
• GrundySMCleemanJIMerzCNImplications of recent clinical trials for the national cholesterol education program adult treatment panel III guidelinesJ Am Coll Cardiol2004447203215358046
   PubMed Web of Science ®Google Scholar
• HiroseNBlankenshipDTKrivanekMAIsolation and characterization of four heparin binding cyanogen bromide peptides of human plasma apolipoprotein BBiochemistry1987265505123676266
   PubMed Web of Science ®Google Scholar
• HortonJDShimanoHHamiltonRLDisruption of LDL receptor gene in transgenic SREBP-1a mice unmask hyperlipidemia resulting from production of lipid-rich VLDLJ Clin Invest199910310677610194480
   PubMed Web of Science ®Google Scholar
• Hurt-CamejoEParedesSMasanaLElevated levels of small low-density lipoprotein with high affinity for arterial matrix components in patients with rheumatoid arthritis: possible contribution of phospholipase A2 to this atherogenic profileArthritis Rheum2001442761711762936
   PubMed Web of Science ®Google Scholar
• IveriusP-HThe interaction between human plasma lipoproteins and connective tissue glycosaminoglycansJ Biol Chem19722472607134336380
   PubMed Web of Science ®Google Scholar
• JiangXCLiZLiuRPhospholipid transfer protein deficiency impairs apolipoprotein-B secretion from hepatocytes by stimulating a proteolytic pathway through a relative deficiency of vitamin E and an increase in intracellular oxidantsJ Biol Chem2005280183364015734742
   PubMed Web of Science ®Google Scholar
• JohnsonAEHaighNGThe ER translocon and retrotranslocation: is the shift into reverse manual or automatic?Cell20001027091211030614
   PubMed Web of Science ®Google Scholar
• JohnsonAEvan WaesMAThe translocon: a dynamic gateway at the ER membraneAnnu Rev Cell Dev Biol19991579984210611978
   PubMed Web of Science ®Google Scholar
• Joint British Societies’JBS 2: guidelines on prevention of cardiovascular disease in clinical practiceHeart200591Suppl 5v15216365341
   PubMedGoogle Scholar
• KennedyMABarreraGCNakamuraKABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulationCell Metab200511213116054053
   PubMed Web of Science ®Google Scholar
• KleizenBBraakmanIProtein folding and quality control in the endoplasmic reticulumCurr Opin Cell Biol200416343915261665
   PubMed Web of Science ®Google Scholar
• KluckenJBuchlerCOrsoEABCG1 (ABC8) the human homolog of the Drosophila white gene is a regulator of macrophage cholesterol and phospholipid transportProc Natl Acad Sci USA2000978172210639163
   PubMed Web of Science ®Google Scholar
• KostovaZWolfDHFor whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connectionEmbo J20032223091712743025
   PubMed Web of Science ®Google Scholar
• KrimbouLMarcilMGenestJNew insights into the biogenesis of human high-density lipoproteinsCurr Opin Lipidol2006172586716680030
   PubMed Web of Science ®Google Scholar
• KugiyamaKOtaYTakazoeKCirculating levels of secretory type II phospholipase A(2) predict coronary events in patients with coronary artery diseaseCirculation19991001280410491371
   PubMed Web of Science ®Google Scholar
• LarssonSLSkogsbergJBjorkegrenJThe Low Density Lipoprotein Receptor Prevents Secretion of Dense ApoB100-containing Lipoproteins from the LiverJ Biol Chem2004279831614583618
   PubMed Web of Science ®Google Scholar
• LewisGFRaderDJNew insights into the regulation of HDL metabolism and reverse cholesterol transportCirc Res20059612213215976321
   PubMed Web of Science ®Google Scholar
• LiLStillemark-BilltonPBeckCEpigallocatechin gallate increases the formation of cytosolic lipid droplets and decreases the secretion of apoB-100 VLDLJ Lipid Res200647677716227197
   PubMed Web of Science ®Google Scholar
• LiangJ-SWuXFisherEAThe amino-terminal domain of apolipoprotein B does not undergo retrograde translocation from the endoplasmic reticulum to the cytosol Proteasomal degradation of nascent apolipoprotein B begins at the carboxyl terminus of the protein while apolipoprotein B is still in its original transloconJ Biol Chem2000275320031010922368
   PubMed Web of Science ®Google Scholar
• Lippincott-SchwartzJRobertsTHHirschbergKSecretory protein trafficking and organelle dynamics in living cellsAnnu Rev Cell Dev Biol2000165578911031247
   PubMed Web of Science ®Google Scholar
• LiuPYingYZhaoYChinese hamster ovary K2 cell lipid droplets appear to be metabolic organelles involved in membrane trafficJ Biol Chem200427937879214597625
   PubMed Web of Science ®Google Scholar
• LondosCBrasaemleDLSchultzCJPerilipins ADRP and other proteins that associate with intracellular neutral lipid droplets in animal cellsSemin Cell Dev Biol19991051810355028
   PubMed Web of Science ®Google Scholar
• LucGBardJMFerrieresJValue of HDL cholesterol apolipoprotein A-I lipoprotein A-I and lipoprotein A-I/A-II in prediction of coronary heart disease: the PRIME Study Prospective Epidemiological Study of Myocardial InfarctionArterioscler Thromb Vasc Biol20022211556112117731
   PubMed Web of Science ®Google Scholar
• MagnussonBAspLBostromPAdipocyte differentiation-related protein promotes fatty acid storage in cytosolic triglycerides and inhibits secretion of very low-density lipoproteinsArterioscler Thromb Vasc Biol20062615667116627799
   PubMed Web of Science ®Google Scholar
• MarchesanDRutbergMAnderssonLA phospholipase D-dependent process forms lipid droplets containing caveolin adipocyte differentiation-related protein and vimentin in a cell-free systemJ Biol Chem20032782729330012730229
   PubMed Web of Science ®Google Scholar
• MarcilMBrooks-WilsonACleeSMMutations in the ABC1 gene in familial HDL deficiency with defective cholesterol effluxLancet19993541341610533863
   PubMed Web of Science ®Google Scholar
• MartinSPartonRGLipid droplets: a unified view of a dynamic organelle Nat Rev Mol Cell Biol20067373816550215
   PubMed Web of Science ®Google Scholar
• MitchellDMZhouMPariyarathRApoprotein B 100 har a prolonged interaction with the translocon during which its lipidation and translocation change from dependence on the microsomal triglyceride transfer protein to independenceProc Natl Acad Sci USA1998951473389843958
   PubMed Web of Science ®Google Scholar
• NestoRWRutterMKImpact of the atherosclerotic process in patients with diabetesActa Diabetol200239Suppl 2S22812222624
   PubMedGoogle Scholar
• NichollsSJCutriBWorthleySGImpact of short-term administration of high-density lipoproteins and atorvastatin on atherosclerosis in rabbitsArterioscler Thromb Vasc Biol2005252416116141405
   PubMed Web of Science ®Google Scholar
• NickelWBruggerBWielandFTProtein and lipid sorting between the endoplasmic reticulum and the Golgi complexSemin Cell Dev Biol199894935019835636
   PubMed Web of Science ®Google Scholar
• NickelWWielandFTBiosynthetic protein transport through the early secretory pathwayHistochem Cell Biol1998109477869681629
   PubMed Web of Science ®Google Scholar
• NissenSETsunodaTTuzcuEMEffect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trialJama2003290229230014600188
   PubMed Web of Science ®Google Scholar
• OlinKLPotter-PerigoSBarrettLipoprotein lipase enhances the binding of native and oxidized low density lipoproteins to versican and biglycan synthesized by cultured arterial smooth muscle cellsJ Biol Chem199927434629610574927
   PubMed Web of Science ®Google Scholar
• OlofssonS-OAspLBorénJThe assembly and secretion of apolipoprotein B-containing lipoproteinsCurr Opin Lipidol199910341610482137
   PubMed Web of Science ®Google Scholar
• OramJFVaughanAMATP-Binding cassette cholesterol transporters and cardiovascular diseaseCirc Res20069910314317095732
   PubMed Web of Science ®Google Scholar
• OutRHoekstraMHildebrandRBMacrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient miceArterioscler Thromb Vasc Biol200626229530016857950
   PubMed Web of Science ®Google Scholar
• OutRHoekstraMMeursITotal Body ABCG1 Expression Protects Against Early Atherosclerotic Lesion Development in MiceArterioscler Thromb Vasc Biol2007
   Web of Science ®Google Scholar
• PariyarathRWangHAitchisonJDCo-translational interactions of apoprotein B with the ribosome and translocon during lipoprotein assembly or targeting to the proteasomeJ Biol Chem20012765415011022045
   PubMed Web of Science ®Google Scholar
• PentikainenMOOorniKKovanenPTLipoprotein lipase (LPL) strongly links native and oxidized low density lipoprotein particles to decorin-coated collagen Roles for both dimeric and monomeric forms of LPLJ Biol Chem2000275569470110681554
   PubMed Web of Science ®Google Scholar
• PischonTGirmanCJSacksFMNon-high-density lipoprotein cholesterol and apolipoprotein B in the prediction of coronary heart disease in menCirculation200511233758316316964
   PubMed Web of Science ®Google Scholar
• RanallettaMWangNHanSDecreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrowArterioscler Thromb Vasc Biol20062623081516917103
   PubMed Web of Science ®Google Scholar
• RemaleyATRustSRosierMHuman ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindredProc Natl Acad Sci USA199996126859010535983
   PubMed Web of Science ®Google Scholar
• RossRAtherosclerosis—an inflammatory diseaseN Engl J Med1999340115269887164
   PubMed Web of Science ®Google Scholar
• RossRGlomsetJHarkerLResponse to injury and atherogenesisAm J Pathol19778667584842616
   PubMed Web of Science ®Google Scholar
• RustSRosierMFunkeHTangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1Nat Genet199922352510431238
   PubMed Web of Science ®Google Scholar
• RustaeusSStillemarkPLindbergKThe microsomal triglyceride transfer protein catalyzes the post-translational assembly of apolipoprotein B-100 very low density lipoprotein in McA-RH7777 cellsJ Biol Chem199827351962039478974
   PubMed Web of Science ®Google Scholar
• SalterAMWigginsDSessionsVAThe intracellular triacylglycerol/fatty acid cycle: a comparison of its activity in hepatocytes which secrete exclusively apolipoprotein (apo) B100 very-low-density lipoprotein (VLDL) and in those which secrete predominantly apoB48 VLDLJ Biochem1998332Pt 366772
   Google Scholar
• SartipyPBondjersGHurt-CamejoEPhospholipase A2 type II binds to extracellular matrix biglycan: modulation of its activity on LDL by colocalization in glycosaminoglycan matrixesArterioscler Thromb Vasc Biol1998181934419848887
   PubMed Web of Science ®Google Scholar
• SchroderMKaufmanRJThe Mammalian Unfolded Protein ResponseAnnu Rev Biochem2005747398915952902
   PubMed Web of Science ®Google Scholar
• SegrestJPJonesMKDe LoofHStructure of apolipoprotein B-100 in low density lipoproteinsJ Lipid Res20014213466711518754
   PubMed Web of Science ®Google Scholar
• ShelnessGSSellersJAVery-low-density lipoprotein assembly and secretionCurr Opin Lipidol200112151711264986
   PubMed Web of Science ®Google Scholar
• SitiaRBraakmanIQuality control in the endoplasmic reticulum protein factoryNature2003426891414685249
   PubMed Web of Science ®Google Scholar
• SkalenKGustafssonMRydbergEKSubendothelial retention of atherogenic lipoproteins in early atherosclerosisNature2002417750412066187
   PubMed Web of Science ®Google Scholar
• SnidermanADApplying apoB to the diagnosis and therapy of the atherogenic dyslipoproteinemias: a clinical diagnostic algorithm Curr Opin Lipidol200415433815243216
   PubMed Web of Science ®Google Scholar
• SnidermanADFurbergCDKeechAApolipoproteins versus lipids as indices of coronary risk and as targets for statin treatmentLancet20033617778012620753
   PubMed Web of Science ®Google Scholar
• SpangAARF1 regulatory factors and COPI vesicle formationCurr Opin Cell Biol200214423712383792
   PubMed Web of Science ®Google Scholar
• SteinbergDParthasarathySCarewTEBeyond cholesterol Modifications of low-density lipoprotein that increase its atherogenicityN Engl J Med1989320915242648148
   PubMed Web of Science ®Google Scholar
• StillemarkPBorénJAnderssonMThe assembly and secretion of apolipoprotein-B48-containing very low density lipoproteins in McA-RH7777 cellsJ Biol Chem2000275105061310744742
   PubMed Web of Science ®Google Scholar
• Stillemark-BilltonPBeckCBorenJRelation of the size and intracellular sorting of apoB to the formation of VLDL 1 and VLDL 2J Lipid Res2005461041415520448
   PubMed Web of Science ®Google Scholar
• TaghibiglouCRashid-KolvearFVan IderstineSCHepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistanceJ Biol Chem200227779380311598116
   PubMed Web of Science ®Google Scholar
• TaskinenMRDiabetic dyslipidaemia: from basic research to clinical practiceDiabetologia2003467334912774165
   PubMed Web of Science ®Google Scholar
• TwiskJGillian-DanielDLTebonAThe role of the LDL receptor in apolipoprotein B secretionJ Clin Invest20001055213210683382
   PubMed Web of Science ®Google Scholar
• WalldiusGJungnerIThe apoB/apoA-I ratio: a strong new risk factor for cardiovascular disease and a target for lipid-lowering therapy—a review of the evidenceJ Intern Med200625949351916629855
   PubMed Web of Science ®Google Scholar
• VaughanAMOramJFABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDLJ Lipid Res20064724334316902247
   PubMed Web of Science ®Google Scholar
• WeisgraberKHRallSCJrHuman apolipoprotein B100 heparin-binding sitesJ Biol Chem1987262110971033301850
   PubMed Web of Science ®Google Scholar
• WigginsDGibbonsGFThe lipolysis/esterification cycle of hepatic triacylglycerol Its role in the secretion of very-low-density lipoprotein and its response to hormones and sulphonylureasJ Biochem199228445762
   Google Scholar
• VijayagopalPSrinivasanSRRadhakrishnamurthyBInteraction of serum lipoproteins and a proteoglycan from bovine aortaJ Biol Chem19812568234417263647
   PubMed Web of Science ®Google Scholar
• WilliamsKJBrociaRWFisherEAThe unstirred water layer as a site of control of apolipoprotein B secretionJ Biol Chem19902651674142170353
   PubMed Web of Science ®Google Scholar
• WilliamsKJTabasIThe response-to-retention hypothesis of early atherogenesisArterioscler Thromb Vasc Biol199515551617749869
   PubMed Web of Science ®Google Scholar
• WilliamsKJTabasIThe response-to-retention hypothesis of atherogenesis reinforcedCurr Opin Lipidol1998947149812202
   PubMed Web of Science ®Google Scholar
• WillnerELTowBBuhmanKKDeficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient miceProc Natl Acad Sci USA20031001262712538880
   PubMed Web of Science ®Google Scholar
• YokoyamaSAssembly of high density lipoprotein by the ABCA1/apolipoprotein pathwayCurr Opin Lipidol2005162697915891387
   PubMed Web of Science ®Google Scholar
• YusufSHawkenSOunpuuSEffect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control studyLancet20043649375215364185
   PubMed Web of Science ®Google Scholar