A review of the safety and efficacy of nebivolol in the mildly hypertensive patient

References

• BenetosARudnichiASafarMPulse pressure and cardiovascular mortality in normotensive and hypertensive subjectsHypertension19983256049740626
   PubMed Web of Science ®Google Scholar
• BenetosASafarMRudnichiAPulse pressure:a predictor of long-term cardiovascular mortality in a French male populationHypertension199730141059403561
   PubMed Web of Science ®Google Scholar
• BlacherJGuerinAPPannierBImpact of aortic stiffness on survival in end-stage renal diseaseCirculation1999992434910318666
   PubMed Web of Science ®Google Scholar
• BlacherJStaessenJGirerdXPulse pressure not mean pressure determines cardiovascular risk in older hypertensive patientsArch Int Med20001601085910789600
   PubMed Web of Science ®Google Scholar
• BonapaceSRossiACicoiraMAortic distensibility independently affects exercise tolerance in patients with dilated cardiomyopathyCirculation20031071603812668493
   PubMed Web of Science ®Google Scholar
• BoutouyriePTropeanoAIAsmarRAortic stiffness is an independent predictor of primary coronary events in hypertensive patientsHypertension20023910511799071
   PubMed Web of Science ®Google Scholar
• BowmanAJChenCP-HFordGANitric oxide mediated venodilator effects of nebivololBr J Clin Pharmacol1994381992047826820
   PubMed Web of Science ®Google Scholar
• Breithaupt-GroglerKLeschingerMBelzGGButzerRErbKde MeyCSinnWInfluence of antihypertensive therapy with cilazapril and hydrochlorothiazide on the stiffness of the aortaCardiovasc Drugs Ther19961049578723170
   PubMed Web of Science ®Google Scholar
• BrunnerHCockcroftJRDeanfieldJEndothelial function and dysfunction. Part II: association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of HypertensionJ Hypertens2005232334615662207
   PubMed Web of Science ®Google Scholar
• CarlbergBSamuelssonOLindholmLHAtenolol in hypertension: is it a wise choice?Lancet20043641684915530629
   PubMed Web of Science ®Google Scholar
• ChenCP-HTingC-TLinS-JDifferent effects of fosinipril and atenolol on wave reflection in hypertensive patientsHypertension1995251034417737712
   PubMed Web of Science ®Google Scholar
• CleophasTJAgrawalRLichtenthalANationwide efficacy-safety study of nebivolol in mildly hypertensive patientsAm J Ther200613192716772759
   PubMedGoogle Scholar
• CleophasTJGrabowskyINiemeyerMGLong-term efficacy of nebivolol monotherapy in patients with hypertensionCurr Ther Res20016245161
   Web of Science ®Google Scholar
• CockcroftJRChowienczykPJBrettSENebivolol vasodilates human forearm vasculature: evidence for an L-arginine/NO-dependent mechanismJ Pharmacol Exp Ther19952741067717562470
   PubMed Web of Science ®Google Scholar
• CockcroftJRWilkinsonIBWebbDJThe Trevor Howell Lecture: age, arterial stiffness and the endotheliumAgeing1997265360
   Google Scholar
• CruickshankJMPrichardBNCBeta-blockers in clinical practice1987EdinburghChurchill Livingstone
   Google Scholar
• CruickshankKRisteLAndersonSGAortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance. An integrated index of vascular function?Circulation200210620859012379578
   PubMed Web of Science ®Google Scholar
• DawesMBrettSEChowienczykPJMantTGKThe vasodilator action of nebivolol in forearm vasculature of subjects with essential hypertensionJ Clin Pharmacol1999484603
   Web of Science ®Google Scholar
• De CreeJGeukensHVerhaegenHNon-invasive cardiac haemodynamics of nebivololClin Drug Investig19913Suppl 12530
   Google Scholar
• DhakamZMcEnieryCMYasminAtenolol and eprosartan:differential effects on central blood pressure and aortic pulse wave velocityAm J Hypertens200619214916448896
   PubMed Web of Science ®Google Scholar
• DrearyAJSchumannALMurfetHInfluence of drugs and gender on the arterial pulse wave and natiuretic peptide secretion in untreated patients with essential hypertensionClin Sci2002103493912401122
   PubMed Web of Science ®Google Scholar
• ErdoganDGulluHCaliskanMNebivolol improves coronary flow reserve in patients with idiopathic dilated CardiomyopathyHeart2007933192417065184
   PubMed Web of Science ®Google Scholar
• FalloisJVFaulhaberH-DNebivolol, a third generation beta-blocker:the current treatment of arterial hypertensionPraxis2001904354111293936
   PubMedGoogle Scholar
• FlatherMDShibataMCCoatsAJRandomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS)Eur Heart J2005262152515642700
   PubMed Web of Science ®Google Scholar
• FogariRZoppiALazzariPComparative effects of nebivolol and atenolol on blood pressure and insulin sensitivity in hypertensive patients with type II diabetesJ Hum Hypertens19971175379416986
   PubMed Web of Science ®Google Scholar
• GaoYNagaoTBondRANebivolol induces endothelium-dependent relaxations of canine coronary arteriesJ Cardiovasc Pharmacol19911796491714022
   PubMed Web of Science ®Google Scholar
• KampOSieswerdaGTVisserCAComparison of effects on systolic and diastolic left ventricular function of nebivolol versus atenolol in patients with uncomplicated essential hypertensionAm J Cardiol200392344812888152
   PubMed Web of Science ®Google Scholar
• KannelWBWilsonPWZhangTJThe epidemiology of impaired glucose tolerance and hypertensionAm Heart J19911211268732008855
   PubMed Web of Science ®Google Scholar
• KassDAAge-related changes in venticular-arterial coupling: pathophysiologic implicationsHeart Fail Rev20027516211790922
   PubMedGoogle Scholar
• KawaguchiMHayIFeticsBCombined ventricular systolic and arterial stiffening in patients with heart failure and preserved ejection fraction: implications for systolic and diastolic reserve limitationsCirculation200310771472012578874
   PubMed Web of Science ®Google Scholar
• KellyRDaleyJAvolioAArterial dilation and reduced wave reflection. Benefit of dilevalol in hypertensionHypertension19891414212737733
   PubMed Web of Science ®Google Scholar
• KinlaySCreagerMAFukumotoMEndothelium-derived nitric oxide regulates arterial elasticity in human arteries in vivoHypertension20013810495311711496
   PubMed Web of Science ®Google Scholar
• LacourciereYArnottWPlacebo-controlled comparison of the effects of nebivolol and low-dose hydrochlorothiazide as monotherapies and in combination on blood pressure and lipid profile in hypertensive patientsJ Hum Hypertens1994828388021909
   PubMed Web of Science ®Google Scholar
• LacourciereYPoirierLLefebvreJComparative effects of a new cardioselective beta-blocker nebivolol and nifedipine sustained-release on 24-hour ambulatory blood pressure and plasma lipoproteinsJ Clin Pharmacol19923266061353507
   PubMed Web of Science ®Google Scholar
• LaurentSBoutouyriePAsmarRAortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patientsHypertension20013712364111358934
   PubMed Web of Science ®Google Scholar
• LindholmLHCarlbergBSamuelssonOShould beta-blockers remain first choice in the treatment of primary hypertension? A meta-analysisLancet200536615455316257341
   PubMed Web of Science ®Google Scholar
• LombardoRMReinaCAbrignaniMGEffects of nebivolol versus carvedilol on left ventricular function in patients with chronic heart failure and reduced left ventricular systolic functionAm J CardiovascDrugs2006625963
   PubMedGoogle Scholar
• MasonRPNitric oxide mechanisms in the pathogenesis of global riskJ Clin Hypertens (Greenwich)2006831816894246
   PubMedGoogle Scholar
• MasonRPKalinowskiLJacobRFNebivolol reduces nitroxidative stress and restores nitric oxide bioavailability in endothelium of black AmericansCirculation2005112379580116330685
   PubMed Web of Science ®Google Scholar
• MazzaAGil-ExtremeraBMaldonatoANebivolol vs amlodipine as first-line treatment of essential arterial hypertension in the elderlyBlood Press200211182812126265
   PubMed Web of Science ®Google Scholar
• McEnieryCMSchmittMQasemANebivolol increases arterial distensibility in vivoHypertension2004443051015262912
   PubMed Web of Science ®Google Scholar
• MeaumeSBenetosAHenryOFAortic pulse wave velocity predicts cardiovascular mortality in subjects. >70 years of ageArterioscler Thromb Vasc Biol20012120465011742883
   PubMed Web of Science ®Google Scholar
• MillarJALeverAFBurkeVPulse pressure as a risk factor for cardiovascular events in the MRC Mild Hypertension TrialJ Hypertens19991710657210466460
   PubMed Web of Science ®Google Scholar
• MitchellGFMoyeLABraunwaldESphygomanometrically determined pulse pressure is a powerful independent predictor of recurrent events after myocardial infarction in patients with impaired left ventricular functionCirculation1997964254609416890
   PubMed Web of Science ®Google Scholar
• MitchellGFTardifJCArnoldJMPulsatile hemodynamics in congestive heart failureHypertension2001381433911751731
   PubMed Web of Science ®Google Scholar
• MoncadaSNitric oxideJ Hypertens Suppl199412S35S97539493
   PubMedGoogle Scholar
• MottramPMHaluskaBALeanoRRelation of arterial stiffness to diastolic dysfunction in hypertensive heart diseaseHeart2005911551616287739
   PubMed Web of Science ®Google Scholar
• NICEHypertension: Management of Hypertension in Adults in Primamry care – Partial update.NICE2006
   Google Scholar
• O’RourkeMFKellyRPAvolioAPEffects of arterial dilator agents on central systolic pressure and on left ventricular hydraulic loadAm J Cardiol198963381441
   Web of Science ®Google Scholar
• PalatiniPCasigliaEJuliusSHigh heart rate: a risk factor for cardiovascular death in elderly menArch Int Med19991595859210090115
   PubMed Web of Science ®Google Scholar
• PalmerRMAshtonDSMoncadaSVascular endothelial cells synthesize nitric oxide from L-arginineNature198833366463131684
   PubMed Web of Science ®Google Scholar
• PedersenMECockcroftJRThe latest generation of beta-blockers:new pharmacologic propertiesCurr Hypertens Rep200682798616884657
   PubMed Web of Science ®Google Scholar
• RedfieldMMJacobsenSJBorlaugBAAge- and gender-related ventricular-vascular stiffening: a community-based studyCirculation200511222546216203909
   PubMed Web of Science ®Google Scholar
• ResnickLMLesterMHDifferential effects of antihypertensive drug therapy on arterial complianceAm J Hypertens200215109610012460707
   PubMed Web of Science ®Google Scholar
• RitterJMNebivolol: endothelium-mediated vasodilating effectJ Cardiovasc Pharmacol200138Suppl 3S13S1611811387
   PubMedGoogle Scholar
• RobertsonJISBallSGHypertension for the clinician1994LondonW.B. Saunders
   Google Scholar
• SchmittMAvolioAQasemABasal NO locally modulates human iliac artery function in vivoHypertension2005462273115867142
   PubMed Web of Science ®Google Scholar
• ShibataMFlatherMWangWSystematic review of the impact of beta blockers on mortality and hospital admissions in heart failureEur J Heart Failure200133517
   PubMed Web of Science ®Google Scholar
• StaessenJWangJ-GThijsLCardiovascular prevention and blood pressure reduction: a quantitative overview updated until March 2003Hypertension200321105576
   Web of Science ®Google Scholar
• SteinerSSFriedhoffAJWilsonBLAntihypertensive therapy and quality of life: comparison of atenolol, enalapril and propanololJ Hum Hypertens19904217252194029
   PubMed Web of Science ®Google Scholar
• StoleruLWijnsWvan EyllCEffects of d-nebivolol and l-nebivolol on left ventricular systolic and diastolic function: comparison with dl-nebivolol and atenololJ Cardiovasc Pharmacol199322183907692155
   PubMed Web of Science ®Google Scholar
• TzemosNLimPOMacDonaldTMNebivolol reverses endothelial dysfunction in essential hypertensionCirculation20011045111411479245
   PubMed Web of Science ®Google Scholar
• UhlirOFejifusaMHavranekKNebivolol versus metoprolol in the treatment of hypertensionClin Drug Investig19913Suppl 110710
   Google Scholar
• Van BortelLMBulpittCJFiciFQuality of life and antihypertensive effect with nebivolol and losartanAm J Hypertens2005181060616296572
   PubMed Web of Science ®Google Scholar
• Van BortelLMABBreedJGSJoostenJNebivolol in hypertension: a double-blind placebo-controlled multicenter study assessing its antihypertensive efficacy and impact on quality of lifeJ Cardiovasc Pharmacol199321856627687708
   PubMed Web of Science ®Google Scholar
• Van BortelLMABde HoonJNJMKoolMJPharmacological properties of nebivolol in manEur J Clin Pharmacol199751379849049578
   PubMed Web of Science ®Google Scholar
• Van BortelLMABKoolMJBoudierHAEffects of antihypertensive agents on local arterial distensibility and complianceHypertension19952653147649594
   PubMed Web of Science ®Google Scholar
• Van BortelLMABVan BaakMAExercise tolerance with nebivolol and atenololCardiovasc Drugs Ther19926239471353367
   PubMed Web of Science ®Google Scholar
• Van de WaterAJanssensWJVan NuetenLPharmacological and hemodynamic profile of nebivolol, a chemically novel, potent and selective beta1-adrenergic antagonistJ Cardiovasc Pharmacol198811552632455841
   PubMed Web of Science ®Google Scholar
• Van MerodeTVan BortelLMABSmeetsFAVerapamil and nebivolol improve carotid artery distensibility in hypertensive patientsJ Hypertens1989Suppl 7S262S3
   Google Scholar
• Van NuetenLDe CreeJNebivolol: a comparison of the effects of dl-nebivolol, d-nebivolol, l-nebivolol, atenolol, and placebo on exercise-induced increases in heart rate and systolic blood pressureCardiovasc Drugs Therap199812339449825177
   PubMed Web of Science ®Google Scholar
• Van NuetenLDupontAGVertommenCA dose-response trial of nebivolol in essential hypertensionJ Hum Hypertens1997a11139449140802
   PubMed Web of Science ®Google Scholar
• Van NuetenLLacourciereYVyssoulisGNebivolol versus nifedipine in the treatment of essential hypertension: a double-blind randomised comparative trialAm J Therap1998a52374310099065
   PubMedGoogle Scholar
• Van NuetenLSchellingAVertommenCNebivolol versus enalapril in the treatment of essential hypertension:a double-blind randomised trialJ Hum Hypertens1997b11813199468009
   PubMed Web of Science ®Google Scholar
• Van NuetenLTaylorFRRobertsonJINebivolol vs atenolol and placebo in essential hypertension: a double-blind randomised trialJ Hum Hypertens1998b12135409504355
   PubMed Web of Science ®Google Scholar
• Van NuetenLTaylorFRRobertsonJISNebivolol versus atenolol and placebo in essential hypertension: a double-blind randomised trialJ Hum Hypertens1998c12135409504355
   PubMed Web of Science ®Google Scholar
• van PopeleNMMattace-RasoFUVliegenthartRAortic stiffness is associated with atherosclerosis of the coronary arteries in older adults: the Rotterdam StudyJ Hypertens2006242371617082718
   PubMed Web of Science ®Google Scholar
• WHO-ISHHypertension guidelinesJ Hypertens1999171518310067786
   PubMed Web of Science ®Google Scholar
• WilkinsonIBFranklinSSCockcroftJRNitric oxide and the regulation of large artery stiffness: from physiology to pharmacologyHypertension200444112615262901
   PubMed Web of Science ®Google Scholar
• WilkinsonIBMcEnieryCMCockcroftJRAtenolol and cardiovascular risk: an issue close to the heartLancet2006367627916503444
   PubMed Web of Science ®Google Scholar
• WilkinsonIBQasemAMcEnieryCMNitric oxide regulates local arterial distensibility in vivoCirculation2002105213711790703
   PubMed Web of Science ®Google Scholar
• WilliamsBLacyPSThomSMDifferential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) studyCirculation200611312132516476843
   PubMed Web of Science ®Google Scholar
• YambeMTomiyamaHHirayamaYArterial stiffening as a possible risk factor for both atherosclerosis and diastolic heart failureHypertens Res2004276253115750255
   PubMed Web of Science ®Google Scholar