References
- BeghettiMCongenital heart disease and pulmonary hypertensionRev Port Cardiol200423227328115116461
- HaworthSGThe management of pulmonary hypertension in childrenArch Dis Child200893762062518381346
- BeghettiM[Pulmonary arterial hypertension in children: new therapeutic approaches]Ann Fr Anesth Reanim200726657057517524605
- HumbertMSitbonOSimonneauGTreatment of pulmonary arterial hypertensionN Engl J Med200430;351141425143615459304
- RashidAIvyDSevere paediatric pulmonary hypertension: new management strategiesArch Dis Child2005901929815613526
- RosenzweigEBBarstRJPulmonary arterial hypertension in children: a medical updateCurr Opin Pediatr200820328829318475097
- GalieNTorbickiABarstRDartevellePHaworthSHigenbottamTGuidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of CardiologyEur Heart J200425242243227815589643
- RubinLJMendozaJHoodMMcGoonMBarstRWilliamsWBTreatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol). Results of a randomized trialAnn Intern Med199011274854912107780
- SimonneauGBarstRJGalieNNaeijeRRichSBourgeRCContinuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary hypertensionAm J Respir Crit Care Med20021651511779720
- OlschewskiHSimonneauGGalieNHigenbottamTNaeijeRRubinLJInhaled iloprost for severe pulmonary hypertensionN Engl J Med2002347532232912151469
- ChannickRNSimonneauGSitbonORobbinsIMFrostATapsonVFEffects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled studyLancet200135892881119112311597664
- RubinLJBadeschDBBarstRJGalieNBlackCMKeoghABosentan therapy for pulmonary arterial hypertensionN Engl J Med20023461289690311907289
- GalieNOlschewskiHOudizRJTorresFFrostAGhofraniHAAmbrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2Circulation2008117233010301918506008
- GalieNGhofraniHATorbickiABarstRJRubinLJBadeschDSildenafil citrate therapy for pulmonary arterial hypertensionN Engl J Med2005353202148215716291984
- BeghettiMCurrent treatment options in children with pulmonary arterial hypertension and experiences with oral bosentanEur J Clin Invest200636Suppl 3162416919006
- YungDWidlitzACRosenzweigEBKersteinDMaislinGBarstRJOutcomes in children with idiopathic pulmonary arterial hypertensionCirculation2004110666066515289375
- BarstRJMaislinGFishmanAPVasodilator therapy for primary pulmonary hypertension in childrenCirculation19;9991197120810069788
- MoncadaSGryglewskiRBuntingSVaneJRAn enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregationNature19762635579663665802670
- MoncadaSVaneJRArachidonic acid metabolites and the interactions between platelets and blood-vessel wallsN Engl J Med19793002011421147219340
- GrantSMGoaKLIloprost. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in peripheral vascular disease, myocardial ischaemia and extracorporeal circulation proceduresDrugs19924368899241379160
- VaneJRBottingRMPharmacodynamic profile of prostacyclinAm J Cardiol19957533A10A
- SchermulyRTYilmazHGhofraniHAWoydaKPullamsettiSSchulzAInhaled iloprost reverses vascular remodeling in chronic experimental pulmonary hypertensionAm J Respir Crit Care Med2005172335836315879421
- SchermulyRTKreisselmeierKPGhofraniHASamiduraiAPullamsettiSWeissmannNAntiremodeling effects of iloprost and the dual-selective phosphodiesterase 3/4 inhibitor tolafentrine in chronic experimental pulmonary hypertensionCirc Res20049481101110815031263
- HildebrandMPharmacokinetics and tolerability of oral iloprost in thromboangiitis obliterans patientsEur J Clin Pharmacol199753151569349930
- AiroPRossiMScarsiMDanieliEGrottoloAZambruniADisease-modifying effects of long-term cyclic iloprost therapy in systemic sclerosis. A retrospective analysis and comparison with a control groupClin Exp Rheumatol200725572272718078620
- WalmrathDSchermulyRPilchJGrimmingerFSeegerWEffects of inhaled versus intravenous vasodilators in experimental pulmonary hypertensionEur Respir J1997105108410929163651
- SchermulyRTPullamsettiSSBreitenbachSCWeissmannNGhofraniHAGrimmingerFIloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungsRespir Res20078417257398
- SchermulyRTSchulzAGhofraniHABreitenbachCSWeissmannNHildebrandMComparison of pharmacokinetics and vasodilatory effect of nebulized and infused iloprost in experimental pulmonary hypertension: rapid tolerance developmentJ Aerosol Med200619335336317034310
- OlschewskiHGhofraniHASchmehlTWinklerJWilkensHHoperMMInhaled iloprost to treat severe pulmonary hypertension. An uncontrolled trial. German PPH Study GroupAnn Intern Med20;132643544310733442
- OlschewskiHWalmrathDSchermulyRGhofraniAGrimmingerFSeegerWAerosolized prostacyclin and iloprost in severe pulmonary hypertensionAnn Intern Med199612498208248610951
- McLaughlinVVOudizRJFrostATapsonVFMuraliSChannickRNRandomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertensionAm J Respir Crit Care Med2006174111257126316946127
- SchermulyRTKrupnikETenorHSchudtCWeissmannNRoseFCoaerosolization of phosphodiesterase inhibitors markedly enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension. Maintenance of lung selectivityAm J Respir Crit Care Med200116491694170011719312
- SchermulyRTLeuchteHGhofraniHAWeissmannNRoseFKohstallMZardaverine and aerosolised iloprost in a model of acute respiratory failureEur Respir J200322234234712952271
- GhofraniHARoseFSchermulyRTOlschewskiHWiedemannRKreckelAOral sildenafil as long-term adjunct therapy to inhaled iloprost in severe pulmonary arterial hypertensionJ Am Coll Cardiol200342115816412849677
- SchermulyRTGhofraniHAEnkeBWeissmannNGrimmingerFSeegerWLow-dose systemic phosphodiesterase inhibitors amplify the pulmonary vasodilatory response to inhaled prostacyclin in experimental pulmonary hypertensionAm J Respir Crit Care Med19;160(5 Pt 1):1500150610556112
- BeghettiMBernerMRimensbergerPCLong term inhalation of iloprost in a child with primary pulmonary hypertension: an alternative to continuous infusionHeart2001863E1011514501
- BeghettiMNicodLBarazzone-ArgiroffoCRimensbergerPCNew combined treatments avoided transplantation in a child with severe pulmonary hypertensionHeart200490215414729784
- TissieresPNicodLBarazzone-ArgiroffoCRimensbergerPCBeghettiMAerosolized iloprost as a bridge to lung transplantation in a patient with cystic fibrosis and pulmonary hypertensionAnn Thorac Surg2004783e48e5015337084
- IvyDDDoranAKSmithKJMalloryGBJrBeghettiMBarstRJShort- and long-term effects of inhaled iloprost therapy in children with pulmonary arterial hypertensionJ Am Coll Cardiol200851216116918191742
- ZwisslerBKemmingGHableroKleenMMerkelMHallerMInhaled prostacyclin (PGI2) versus inhaled nitric oxide in adult respiratory distress syndromeAm J Respir Crit Care Med1996154167116778970353
- OlschewskiHGhofraniHAWalmrathDTemmesfeld-WollbruckBGrimmingerFSeegerWRecovery from circulatory shock in severe primary pulmonary hypertension (PPH) with aerosolization of iloprostIntensive Care Med19982466316349681789
- OpitzCFWenselRBettmannMSchaffarczykRLinscheidMHetzerRAssessment of the vasodilator response in primary pulmonary hypertension. Comparing prostacyclin and iloprost administered by either infusion or inhalationEur Heart J200324435636512581683
- De LucaDZeccaEPiastraMRomagnoliCIloprost as ‘rescue’ therapy for pulmonary hypertension of the neonatePaediatr Anaesth200717439439517359413
- ChotigeatUJaratwashirakulSInhaled iloprost for severe persistent pulmonary hypertension of the newbornJ Med Assoc Thai200790116717017621749
- EifingerFSreeramNMehlerKHuenselerCKribsARothBAerosolized iloprost in the treatment of pulmonary hypertension in extremely preterm infants: a pilot studyKlin Padiatr20082202666917710738
- ZwisslerBRankNJaenickeUSchürleBWelteMReichartBSelective pulmonary vasodilation by inhaled prostacyclin in a newborn with congenital heart disease and cardiopulmonary bypassAnesthesiology199582151215167793663
- SitbonOBrenotFDenjeanABergeronAParentFAzarianRInhaled nitric oxide as a screening vasodilator agent in primary pulmonary hypertensionAm J Respir Crit Care Med19951513843897842196
- RobertsJDJrLangPBigatelloLMVlahakesGJZapolWMInhaled nitric oxide in congenital heart diseaseCirculation19938724474538425292
- HoeperMMOlschewskiHGhofraniHAWilkensHWinklerJBorstMMA comparison of the acute hemodynamic effects of inhaled nitric oxide and aerosolized iloprost in primary pulmonary hypertension. German PPH study groupJ Am Coll Cardiol2035117618210636277
- BernerMBeghettiMSpahr-SchopferIOberhansliIFriedliBInhaled nitric oxide to test the vasodilator capacity of the pulmonary vascular bed in children with long-standing pulmonary hypertension and congenital heart diseaseAm J Cardiol19967775325358629600
- RimensbergerPCSpahr-SchopferIBernerMJaeggiEKalangosAFriedliBInhaled nitric oxide versus aerosolized iloprost in secondary pulmonary hypertension in children with congenital heart disease: vasodilator capacity and cellular mechanismsCirculation2001103454454811157720
- HalliogluODilberECelikerAComparison of acute hemodynamic effects of aerosolized and intravenous iloprost in secondary pulmonary hypertension in children with congenital heart diseaseAm J Cardiol20039281007100914556887