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Review

Redefining the role of thiazolidinediones in the management of type 2 diabetes

Pages 141-151 | Published online: 18 Jan 2009

References

  • Department of HealthForecasting obesity to 2010Department of Health82006Available from: http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsStatistics/DH_4138630 (accessed 17 October 2008).
  • AmosAFMcCartyDJZimmetPThe rising global burden of diabetes and its complications: estimates and projections to the year 2010Diabet Med199714S1S859450510
  • FordESPrevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the USDiabetes Care2005282745274916249550
  • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in AdultsExecutive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)JAMA20012852486249711368702
  • DormandyJACharbonnelBEcklandDJSecondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trialLancet20053661279128916214598
  • BloomgardenZTThe Avandia debateDiabetes Care2007302401240817726191
  • WeyerCTataranniPABogardusCPratleyREInsulin resistance and insulin secretory dysfunction are independent predictors of worsening of glucose tolerance during each stage of type 2 diabetes developmentDiabetes Care200124899411194248
  • KahnSEThe importance of the β-cell in the pathogenesis of type 2 diabetes mellitusAm J Med2000108Suppl 6a2S8S10764844
  • DeFronzoRA1988 Lilly Lecture The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDMDiabetes1987376676873289989
  • BergmanRNAderMHueckingKVan CittersGAccurate assessment of β-cell function: the hyperbolic correctionDiabetes200251Suppl 1S212S22011815482
  • UK Prospective Diabetes Study (UKPDS) GroupIntensive blood-glucose control with sulfonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)Lancet19983528378539742976
  • UK Prospective Diabetes Study (UKPDS) GroupUKPDS 16. Overview of 6 years’ therapy of type II diabetes: a progressive diseaseDiabetes199544124912587589820
  • NestoRWThe relation of insulin resistance syndromes to risk of cardiovascular diseaseRev Cardiovasc Med20034Suppl 6S111814668699
  • SmileyTOhPShaneLGThe relationship of insulin resistance measured by reliable indexes to coronary artery disease risk factors and outcomes–a systematic reviewCan J Cardiol20011779780511468646
  • BonoraEFormentiniGCalcaterraFHOMA-estimated insulin resistance is an independent predictor of cardiovascular disease in type 2 diabetic subjects: prospective data from the Verona Diabetes Complications StudyDiabetes Care2002251135114112087010
  • TontonozPSpiegelmanBMFat and beyond: the diverse biology of PPAR-γAnn Rev Biochem20087728931218518822
  • RavnskjærKBørgesenMRubiBPeroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cellsEndocrinology20051463266327615878969
  • SmithSAPeroxisome proliferator-activated receptors and the regulation of mammalian lipid metabolismBiochem Soc Trans200230(Pt 6):1086109012440979
  • OlefskyJMSaltielARPPAR gamma and the treatment of insulin resistanceTrends Endocrinol Metab20001136236811042466
  • FonsecaVARationale for the use of insulin sensitizers to prevent cardiovascular events in type 2 diabetes mellitusAm J Med20071209 Suppl 2S18S2517826042
  • LeiterLACan thiazolidinediones delay disease progression in type 2 diabetes?Curr Med Res Opin2006221193120116846552
  • CalkinACThomasMCPPAR agonists and cardiovascular disease in diabetesPPAR Res2008245410.
  • PatelCBDe LemosJAWyneKLMcGuireDKThiazolidinediones and risk for atherosclerosis: pleiotropic effects of PPARγ agonismDiabetes Vasc Dis Res200636571
  • TurnerRCCullCAFrighiVHolmanRGlycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49)JAMA19992812005201210359389
  • CookMNGirmanCJSteinPPAlexanderCMHolmanRRGlycemic control continues to deteriorate after sulfonylureas are added to metformin among patients with type 2 diabetesDiabetes Care200528995100015855556
  • AronoffSRosenblattSBraithwaiteSEganJWMathisenALSchneiderRLPioglitazone hydrochloride monotherapy improves glycemic control in the treatment of patients with type 2 diabetes: a 6-month randomized placebo-controlled dose-response study. The Pioglitazone 001 Study GroupDiabetes Care2000231605161111092281
  • ScherbaumWAGokeBMetabolic efficacy and safety of once-daily pioglitazone monotherapy in patients with type 2 diabetes: a double-blind, placebo-controlled studyHorm Metab Res20023458959512439788
  • HerzMJohnsDReviriegoJA randomized, double-blind, placebo-controlled, clinical trial of the effects of pioglitazone on glycemic control and dyslipidemia in oral antihyperglycemic medication-naive patients with type 2 diabetes mellitusClin Ther2003251074109512809958
  • LebovitzHEDoleJFPatwardhanRRappaportEBFreedMIfor the Rosiglitazone Clinical Trials Study GroupRosiglitazone monotherapy is effective in patients with type 2 diabetesJ Clin Endocrinol Metab20018628028811232013
  • PhillipsLSGrunbergerGMillerEfor the Rosiglitazone Clinical Trials Study GroupOnce- and twice-daily dosing with rosiglitazone improves glycemic control in patients with type 2 diabetesDiabetes Care20012430831511213884
  • ChiquetteERamirezGDeFronzoRA meta-analysis comparing the effect of thiazolidinediones on cardiovascular risk factorsArch Intern Med20041642097210415505122
  • CharbonnelBHMatthewsDRSchernthanerGHanefeldMBrunettiPfor The QUARTET Study GroupA long-term comparison of pioglitazone and gliclazide in patients with type 2 diabetes mellitus: a randomized, double-blind, parallel-group comparison trialDiabet Med20052239940515787663
  • TanMHBaksiAKrahulecBfor the GLAL Study GroupComparison of pioglitazone and gliclazide in sustaining glycemic control over 2 years in patients with type 2 diabetesDiabetes Care20052854455015735185
  • HällstenKVirtanenKALönnqvistFRosiglitazone but not metformin enhances insulin- and exercise-stimulated skeletal muscle glucose uptake in patients with newly diagnosed type 2 diabetesDiabetes2002513479348512453903
  • PavoIJermendyGVarkonyiTTEffect of pioglitazone compared with metformin on glycemic control and indicators of insulin sensitivity in recently diagnosed patients with type 2 diabetesJ Clin Endocrinol Metab2003881637164512679450
  • HanefeldMBrunettiPSchernthanerGHMatthewsDRCharbonnelBHfor the QUARTET Study GroupOne-year glycemic control with a sulfonylurea plus pioglitazone versus a sulfonylurea plus metformin in patients with type 2 diabetesDiabetes Care20042714114714693980
  • NagasakaSAisoYYoshizawaKIshibashiSComparison of pioglitazone and metformin efficacy using homeostasis model assessmentDiabet Med20042113614114984448
  • CharbonnelBSchernthanerGBrunettiPLong-term efficacy and tolerability of add-on pioglitazone therapy to failing monotherapy compared with addition of gliclazide or metformin in patients with type 2 diabetesDiabetologia2005481093110415889234
  • SchernthanerGMatthewsDRCharbonnelBHanefeldMBrunettiPfor the QUARTET Study GroupEfficacy and safety of pioglitazone versus metformin in patients with type 2 diabetes mellitus: a double-blind, randomized trialJ Clin Endocrinol Metab2004896068607615579760
  • KahnSEHaffnerSMHeiseMAfor the ADOPT Study GroupGlycemic durability of rosiglitazone, metformin, or glyburide mono-therapyN Engl J Med20063552427244317145742
  • TanMHJohnsDStrandJfor the GLAC Study GroupSustained effects of pioglitazone vs glibenclamide on insulin sensitivity, glycaemic control, and lipid profiles in patients with Type 2 diabetesDiabet Med20042185986615270789
  • National Institute for Health and Clinical Excellence (NICE)Type 2 diabetes: the management of type 2 diabetes (update) Available from: http://www.nice.org.uk/CG66 (accessed 17 October 2008).
  • IDF Clinical Guidelines Task ForceGlobal guideline for type 2 diabetes: recommendations for standard, comprehensive, and minimal careDiabet Med20062357959316759299
  • RosenstockJRoodJCobitzABiswasNChouHGarberAInitial treatment with rosiglitazone/metformin fixed-dose combination therapy compared with monotherapy with either rosiglitazone or metformin in patients with uncontrolled type 2 diabetesDiabetes Obes Metab2006865066017026489
  • NathanDMBuseJBDavidsonMBManagement of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapyDiabetologia2006491711172116802130
  • FonsecaVRosenstockJPatwardhanRSalzmanAEffect of metformin and rosiglitazone combination therapy in patients with type 2 diabetes mellitusJAMA20002831695170210755495
  • BaileyCJBagdonasARubesJRosiglitazone/metformin fixed dose combination compared with uptitrated metformin alone in type 2 diabetes mellitus: a 24 week, multicenter, randomized, double blind, parallel group studyClin Ther2005271548156116330291
  • HanefeldMPioglitazone and sulfonylureas: effectively treating type 2 diabetesInt J Clin Pract2007S1532027
  • SmileyTThe role of declining beta cell function in the progression of type 2 diabetes: implications for outcomes and pharmacological managementCan J Diabetes200327277286
  • GastaldelliAFerranniniEMiyazakiYMatsudaMMariADefronzoRAThiazolidinediones improve beta-cell function in type 2 diabetic patientsAm J Physiol Endocrinol Metab2007292E871E88317106061
  • JuhlCBHollingdalMPørksenNPrangeALönnqvistFSchmitzOInfluence of rosiglitizone treatment on β-cell function in type 2 diabetes: evidence of an increased ability of glucose to entrain high-frequency insulin pulsatilityJ Clin Endocrinol Metab2003883794380012915671
  • XiangAPetersRKjosSEffect of pioglitizone on pancreatic β-cell function and diabetes risk in Hispanic women with gestational diabetesDiabetes2006555172216443789
  • TripathyDBanerjiMABrayGAACTos NOW for the Prevention of Diabetes (ACT NOW) Study [Abstract]Diabetologia200851Suppl 1S99
  • DREAM (Diabetes REduction Assessment with ramipril and rosiglitazone Medication) Trial InvestigatorsEffect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trialLancet20063681096110516997664
  • GarberAKleinEBruceSSankohSMohideenPMetformin–glibenclamide versus metformin plus rosiglitazone in patients with type 2 diabetes inadequately controlled on metformin monotherapyDiabetes Obes Metab2006815616316448519
  • HamannAGarcia-PuigJPaulGDonaldsonJStewartMComparison of fixed-dose rosiglitazone/metformin combination therapy with sulfonylurea plus metformin in overweight individuals with type 2 diabetes inadequately controlled on metformin aloneExp Clin Endocrinol Diabetes200811661318095238
  • StewartMWCirkelDTFurusethKEffect of metformin plus roziglitazone compared with metformin alone on glycaemic control in well-controlled Type 2 diabetesDiabet Med2006231069107816978370
  • HomePDPocockSJBeck-NielsenHfor the RECORD Study GroupRosiglitazone evaluated for cardiovascular outcomes–an interim analysisN Engl J Med2007357283817551159
  • DorkhanMFridAA review of pioglitazone HCL and glimepiride in the treatment of type 2 diabetesVasc Health Risk Manag2007372173118078023
  • DerosaGPioglitazone plus glimepiride: a promising alternative in metabolic controlInt J Clin Pract2007S1532836
  • StaelsBMetformin and pioglitazone: Effectively treating insulin resistanceCurr Med Res Opin200622Suppl 2S27S3716914073
  • SeufertJA fixed-dose combination of pioglitazone and metformin: a promising alternative in metabolic controlCurr Med Res Opin200622Suppl 2S39S4816914074
  • MatthewsDRCharbonnelBHHanefeldMBrunettiPSchernthanerGLong-term therapy with addition of pioglitazone to metformin compared with the addition of gliclazide to metformin in patients with type 2 diabetes: a randomized, comparative studyDiabetes Metab Res Rev20052116717415386821
  • KerenyiZSamerHJamesRYanYStewartMCombination therapy with rosiglitazone and glibenclamide compared with upward titration of glibenclamide alone in patients with type 2 diabetes mellitusDiabetes Res Clin Pract20046321322314757293
  • ComaschiMDemicheliADi PietroCBellatrecciaAMarizSfor the COM06 Study InvestigatorsEffects of pioglitazone in combination with metformin or a sulfonylurea compared to a fixed-dose combination of metformin and glibenclamide in patients with type 2 diabetesDiabetes Technol Ther2007938739817705695
  • BetteridgeDJVergesBLong-term effects on lipids and lipoproteins of pioglitazone versus gliclazide addition to metformin and pioglitazone versus metformin addition to sulfonylurea in the treatment of type 2 diabetesDiabetologia2005482477248116283239
  • DerosaGCiceroAFGaddiAA comparison of the effects of pioglitazone and rosiglitazone combined with glimepiride on prothrombotic state in type 2 diabetic patients with the metabolic syndromeDiabetes Res Clin Pract20056951315955382
  • DerosaGGaddiAVPiccinniMNDifferential effect of glimepiride and rosiglitazone on metabolic control of type 2 diabetic patients treated with metformin: a randomized, double-blind, clinical trialDiabetes Obes Metab2006819720516448524
  • EinhornDRendellMRosenzweigJEganJWMathisenALSchneiderRLPioglitazone hydrochloride in combination with metformin in the treatment of type 2 diabetes mellitus: a randomized, placebo-controlled study. The Pioglitazone 027 Study GroupClin Ther2000221395140911192132
  • RosenblattSMiskinBGlazerNBPrinceMJRobertsonKEThe impact of pioglitazone on glycemic control and atherogenic dyslipidemia in patients with type 2 diabetes mellitusCoron Artery Dis20011241342311491207
  • MattooVEcklandDWidelMMetabolic effects of pioglitazone in combination with insulin in patients with type 2 diabetes mellitus whose disease is not adequately controlled with insulin therapy: results of a six-month, randomized, double-blind, prospective, multicenter, parallel-group studyClin Ther20052755456715978304
  • BerhanuPKipnesMSKhanMAEffects of pioglitazone on lipid and lipoprotein profiles in patients with type 2 diabetes and dyslipidaemia after treatment conversion from rosiglitazone while continuing stable statin therapyDiab Vasc Dis Res20063394416784180
  • GoldbergRBKendallDMDeegMAA comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemiaDiabetes Care2005281547155415983299
  • DerosaGD’AngeloARagonesiPDMetformin–pioglitazone and metformin–rosiglitazone effects on non-conventional cardiovascular risk factors plasma level in type 2 diabetic patients with metabolic syndromeJ Clin Pharm Ther20063137538316882108
  • DeegMABuseJBGoldbergRBfor the GLAI Study InvestigatorsPioglitazone and rosiglitazone have different effects on serum lipoprotein particle concentrations and sizes in patients with type 2 diabetes and dyslipidemiaDiabetes Care2007302458246417595355
  • LawrenceJMReidJTaylorGJStirlingCRecklessJPFavorable effects of pioglitazone and metformin compared with gliclazide on lipoprotein subfractions in overweight patients with early type 2 diabetesDiabetes Care200427414614693964
  • PerezAKhanMJohnsonTKarunaratneMPioglitazone plus a sulfonylurea or metformin is associated with increased lipoprotein particle size in patients with type 2 diabetesDiabetes Vasc Dis Res200414450
  • DerosaGD’AngeloARagnonesiPDEffects of rosiglitazone and pioglitazone combined with metformin on the prothrombotic state of patients with type 2 diabetes mellitus and metabolic syndromeJ Int Med Res20063454555517133785
  • GoldsteinBJWeissmanPNWooddellMJWaterhouseBRCobitzARReductions in biomarkers of cardiovascular risk in type 2 diabetes with rosiglitazone added to metformin compared with dose escalation of metformin: an EMPIRE trial sub-studyCurr Med Res Opin2006221715172316968575
  • PfutznerAMarxNLubbenGImprovement of cardiovascular risk markers by pioglitazone is independent from glycemic control: results from the PIONEER studyJ Am Coll Cardiol2005451925193115963388
  • YangWSJengCYWuTYSynthetic peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, increases plasma levels of adiponectin type 2 diabetic patientsDiabetes Care20022537638011815513
  • MazzoneTMeyerPMFeinsteinSBEffect of pioglitazone compared with glimepiride on carotid intima-media thickness in type 2 diabetes: a randomized trialJAMA20062962572258117101640
  • NissenSENichollsSJWolskiKComparison of pioglitazone vs glimepiride on progression of coronary atherosclerosis in patients with type 2 diabetes: the PERISCOPE randomized controlled trialJAMA20082991561157318378631
  • UK Prospective Diabetes Study (UKPDS) GroupEffect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)Lancet19983528548659742977
  • WilcoxRBousserM-GBetteridgeDJfor the PROactive InvestigatorsEffects of pioglitazone in patients with type 2 diabetes with or without previous stroke: results from PROactive (PROspective pioglitAzone Clinical Trial In macroVascular Events 04)Stroke20073886587317290029
  • ErdmannEDormandyJACharbonnelBMassi-BenedettiMMoulesIKSkeneAMfor the PROactive InvestigatorsThe effect of pioglitazone on recurrent myocardial infarction in 2,445 patients with type 2 diabetes and previous myocardial infarction. Results from the PROactive (PROactive 05) studyJ Am Coll Cardiol2007491772178017466227
  • LincoffAMWolskiKNichollsSJNissenSEPioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trialsJAMA20072981180118817848652
  • NissenSEWolskiKEffect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causesN Engl J Med20073562457247117517853
  • Action to Control Cardiovascular Risk in Diabetes Study GroupGersteinHCMillerMEByingtonRPGoffDCJrBiggerJTEffects of intensive glucose lowering in type 2 diabetesN Engl J Med20083582545255918539917
  • DuckworthWCAmerican Diabetes Association 68th Scientific Sessions: VA Diabetes Trial SymposiumPresented 682008
  • RaskinPRendellMRiddleMCDoleJFFreedMIRosenstockJfor the Rosiglitazone Clinical Trials Study GroupA randomized trial of rosiglitazone therapy in patients with inadequately controlled insulin-treated type 2 diabetesDiabetes Care2001241226123211423507
  • BasuAJensenMDMcCannFMukhopadhyayDJoynerMJRizzaRAEffects of pioglitazone versus glipizide on body fat distribution, body water content, and hemodynamics in type 2 diabetesDiabetes Care2006951051416505497
  • BaysHMandarinoLDeFronzoRARole of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approachJ Clin Endocrinol Metab20048946347814764748
  • RyanMacular Edema associated with glitazoneRetina20062656257016770264
  • LiazosSpontaneous resolution of diabetic macular edema after discontinuation of thizolidinedionesDiabet Med20082586086218644073
  • KarallieddeJBuckinghamRStarkieMLorandDStewartMVibertiGfor the Rosiglitazone Fluid Retention Study GroupEffect of various diuretic treatments on rosiglitazone-induced fluid retentionJ Am Soc Nephrol2006173482349017093067
  • GreyABollandMGambleGThe peroxisome proliferator-activated receptor-γ agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: a randomized, controlled trialJ Clin Endocrinol Metab2007921305131017264176
  • BerberogluZGursoyABayraktarNYaziciACBascil TutuncuNGuvener DemiragNRosiglitazone decreases serum bone-specific alkaline phosphatase activity in postmenopausal diabetic womenJ Clin Endocrinol Metab2007923523353017595249
  • GlintborgDAndersenMHagenCHeickendorffLHermannAPAssociation of pioglitazone treatment with decreased bone mineral density in obese premenopausal patients with polycystic ovary syndrome: a randomized, placebo-controlled trialJ Clin Endocrinol Metab2008931696170118285411
  • MeymehRHWooltortonEDiabetes drug pioglitazone (Actos): risk of fractureCMAJ200717772372417823139
  • YaturuSBryantBJainSKThiazolidinediones treatment decreases bone mineral density in type 2 diabetic menDiabetes Care2007301574157617363747
  • LauAHarperWThiazolidinediones and their effect on bone metabolism: a reviewCan J Diabetes200731378383
  • StrattonIMAdlerAINeilHAAssociation of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational studyBMJ200032140541210938048
  • NathanDMBuseJBDavidsonMBFerranniniEHolmanRRSherwinRZinmanBMedical management of hyperglycaemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy. A consensus statement of the American Diabetes Association and the European Association for the Study of DiabetesDiabetes Care200932111