57
Views
0
CrossRef citations to date
0
Altmetric
Short Report

Protein C preserves microcirculation in a model of neonatal septic shock

, , , &
Pages 775-781 | Published online: 10 Sep 2009

References

  • MeadowWFrainLRenYLeeGSonejiSLantosJSerial assessment of mortality in the neonatal intensive care unit by algorithm and intuition: certainty, uncertainty, and informed consentPediatrics2002109587888611986450
  • AsakaSShibayamaYNakataKPathogenesis of focal and random hepatocellular necrosis in endotoxemia: microscopic observation in vivoLiver2006161831878873005
  • TaylorFBJrChangAEsmonCTD’AngeloAVigano-D’AngeloSBlickKEProtein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboonJ Clin Invest1987799189253102560
  • KurosawaSEsmonCTStearns-KurosawaDJThe soluble endothelial protein C receptor binds to activated neutrophils: involvement of proteinase-3 and CD11b/CD18J Immunol20001654697470311035113
  • NoldMFNold-PetryCAFischerDActivated protein C down-regulates p38 mitogen-activated protein kinase and improves clinical parameters in an in-vivo model of septic shockThromb Haemost2007981118112618000619
  • TaylorFBJrStearns-KurosawaDJKurosawaSThe endothelial cell protein C receptor aids in host defense against Escherichia coli sepsisBlood2000951680168610688824
  • WhiteBSchmidtMMurphyCLivingstoneWActivated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNF-alpha) production in the THP-1 monocytic cell lineBr J Haematol200011013013410930989
  • BernardGRVincentJLLaterrePFEfficacy and safety of recombinant human activated protein C for severe sepsisN Engl J Med200134469970911236773
  • NadelSGoldsteinBWilliamsMDDrotrecogin alfa (activated) in children with severe sepsis: a multicentre phase III randomised controlled trialLancet200736983684317350452
  • AlbualiWJSinghRNFraserDDScottLAKorneckiADrotrecogin alfa activated treatment in a neonate with sepsis and multi-organ failureSaudi Med J2005261289129216127532
  • RawiczMSitkowskaBRudzinskaIKornackaMKBochenskiPRecombinant human activated protein C for severe sepsis in a neonateMed Sci Monit20028CS90CS9412444386
  • De CarolisMPPolimeniVPapacciPLacerenzaSRomagnoliCSevere sepsis in a premature baby. protein c replacement therapyTurk J Pediatr200850440540819014060
  • YesilirmakDCKumralATugyanKEffects of activated protein C on neonatal hypoxic ischemic brain injuryBrain Res20081210566218420181
  • KreuzWVeldmannAFischerDSchlosserRVolkWREttingshausenCENeonatal sepsis: a challenge in hemostaseologySemin Thromb Hemost19992553153510632474
  • VenkataseshanSDuttaSAhluwaliaJNarangALow plasma protein C vaules predict mortality in low birth weight neonates with septicemiaPediatr Infect Dis J20072668468817848878
  • IbaTKidokoroAFukunagaMNagakariKShirahamaAIdaYActivated protein C improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat lipopolysaccharide modelCrit Care Med20053336837215699841
  • Genzel-BoroviczenyOStrotgenJHarrisAGMessmerKChristFOrthogonal polarization spectral imaging (OPS): a novel method to measure the microcirculation in term and preterm infants transcutaneouslyPediatr Res20035138639111861946
  • SlaafDWTangelderGJRenemanRSJagerKBollingerAA versatile incident illuminator for intravital microscopyInt J Microcirc Clin Exp198763913973429145
  • GrossJFAroestyJMathematical models of capillary flow: a critical reviewBiorheology197292252644579396
  • LangerSBiberthalerPHarrisAGSteinauHUMessmerKIn vivo monitoring of microvessels in skin flaps: introduction of a novel techniqueMicrosurgery20012131732411754431
  • BiberthalerPLangerSLuchtingBKhandogaAMessmerKIn vivo assessment of colon microcirculation: comparison of the new OPS imaging technique with intravital microscopyEur J Med Res2001652553411772540
  • BoermaECMathuraKRvan der VoortPHSpronkPEInceCQuantifying bedside-derived imaging of microcirculatory abnormalities in septic patients: a prospective validation studyCrit Care20059R601R60616280059
  • De BackerVerdantCChieregoMKochMGulloAVincentJLEffects of drotrecogin alfa activated on microcirculatory alterations in patients with severe sepsisCrit Care Med2006341918192416715034
  • WangZSuFRogiersPVincentJLBeneficial effects of recombinant activated protein C in a ewe model of septic shockCrit Care2007351125942600
  • RussoGLa SpinaMDismaNAstutoMDrotrecogin alfa activated as a treatment for severe sepsis in pediatric cancerBone Marrow Transplant20063857557616921401
  • KylatRIOhlssonARecombinant human activated protein C for severe sepsis in neonatesCochrane Database Syst Rev20062CD00538516625638
  • de KleijnEDde GrootRHackCEActivation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: a randomized, double-blinded, placebo-controlled, dose-finding studyCrit Care Med2003311839184712794428
  • WhiteBLivingstoneWMurphyCHodgsonARaffertyMSmithOPAn open-label study of the role of adjuvant hemostatic support with protein C replacement therapy in purpura fulminans-associated meningococcemiaBlood2000963719372411090052