Bibliography
- Hazelzet JA , DriessenGJA, AbboudP, WheelerDS, ShanleyTP, WongHR: Sepsis. In: Pediatric Critical Care Medicine: Basic Science and Clinical Evidence. Wheeler DS, Wong HR, Shanley TP (Eds). Springer, Berlin, Germany, 1421–1444 (2007).
- Watson RS , CarcilloJA, Linde-ZwirbleWT, ClermontG, LidickerJ, AngusDC: The epidemiology of severe sepsis in children in the United States.Am. J. Respir. Crit. Care Med.167, 695–701 (2003).
- Watson RS , CarcilloJA: Scope and epidemiology of pediatric sepsis.Pediatr. Crit. Care Med.6, S3–5 (2005).
- Carcillo JA , FieldsAI: Clinical practice parameters for hemodynamic support of pediatric and neonatal patients in septicShock. Crit. Care Med.30, 1365–1378 (2002).
- Nadel S , GoldsteinB, WilliamsMD et al.: Drotrecogin α (activated) in children with severe sepsis: a multicentre Phase III randomised controlled trial.Lancet369, 836–843 (2007).
- Laudanski K , Miller-GrazianoC, XiaoW et al.: Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways. Proc. Natl Acad. Sci. USA103, 15564–15569 (2006).
- Calvano SE , XiaoW, RichardsDR et al.: A network-based analysis of systemic inflammation in humans.Nature437, 1032–1037 (2005).
- Cobb JP , MindrinosMN, Miller-Graziano C et al.: Application of genome-wide expression analysis to human health and disease. Proc. Natl Acad. Sci. USA102, 4801–4806 (2005).
- Pachot A , LepapeA, VeyS, BienvenuJ, MouginB, MonneretG: Systemic transcriptional analysis in survivor and non-survivor septic shock patients: a preliminary study.Immunol. Lett.106, 63–71 (2006).
- Prucha M , RurykA, BorissH et al.: Expression profiling: toward an application in sepsis diagnostics.Shock.22, 29–33 (2004).
- Wong HR , ShanleyTP, SakthivelB et al.: Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome.Physiol. Genomics30, 146–155 (2007).
- King JC , ShamesDM, WoodhouseLR: Zinc homeostasis in humans.J. Nutr.130, 1360S–1366S (2000).
- Gaetke LM , McClainCJ, TalwalkarRT, ShedlofskySI: Effects of endotoxin on zinc metabolism in human volunteers.Am. J. Physiol.272, E952–956 (1997).
- Failla ML : Trace elements and host defense: recent advances and continuing challenges.J Nutr.133, 1443S-1447S (2003).
- Fraker PJ , KingLE: Reprogramming of the immune system during zinc deficiency.Annu. Rev. Nutr.24, 277–298 (2004).
- Ibs KH , RinkL: Zinc-altered immune function.J Nutr.133, 1452S–1456S (2003).
- Rink L , HaaseH: Zinc homeostasis and immunity.Trends Immunol.28, 1–4 (2007).
- Shanley TP , CvijanovichN, LinR et al.: Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septicShock. Mol. Med. (2007) [Epub ahead of print].
- Hotchkiss RS , KarlIE: The pathophysiology and treatment of sepsis.N. Engl. J. Med.348, 138–150 (2003).
- Abraham E : Why immunomodulatory therapies have not worked in sepsis.Intensive Care Med.25, 556–566 (1999).
- Ayala A , ChaudryIH: Immune dysfunction in murine polymicrobial sepsis: mediators, macrophages, lymphocytes and apoptosis.Shock6(Suppl.1), S27–S38 (1996).
- Hotchkiss RS , TinsleyKW, KarlIE: Role of apoptotic cell death in sepsis.Scand J. Infect. Dis.35, 585–592 (2003).
- Hotchkiss RS , CoopersmithCM, KarlIE: Prevention of lymphocyte apoptosis--a potential treatment of sepsis?Clin. Infect. Dis.41(Suppl.7), S465–S469 (2005).
- Hotchkiss RS , OsmonSB, ChangKC, WagnerTH, CoopersmithCM, KarlIE: Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways.J. Immunol.174, 5110–5118 (2005).
- Hotchkiss RS , McConnellKW, BullokK et al.: TAT-BH4 and TAT-Bcl-xL peptides protect against sepsis-induced lymphocyte apoptosis in vivo. J. Immunol.176, 5471–5477 (2006).
- Chang KC , UnsingerJ, DavisCG et al.: Multiple triggers of cell death in sepsis: death receptor and mitochondrial-mediated apoptosis.Faseb J.21, 708–719 (2007).
- Chung CS , SongGY, LomasJ, SimmsHH, ChaudryIH, AyalaA: Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity.J. Leukoc. Biol.74, 344–351 (2003).
- Hotchkiss RS , SwansonPE, KnudsonCM et al.: Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis.J. Immunol.162, 4148–4156 (1999).
- Mahidhara R , BilliarTR: Apoptosis in sepsis.Crit. Care Med.28, N105–113 (2000).
- Wesche DE , Lomas-NeiraJL, PerlM, ChungCS, AyalaA: Leukocyte apoptosis and its significance in sepsis and shock.J. Leukoc. Biol.78, 325–337 (2005).
- Hotchkiss RS , SwansonPE, FreemanBD et al.: Apoptotic cell death in patients with sepsis, Shock, and multiple organ dysfunction. Crit. Care Med.27, 1230–1251 (1999).
- Felmet KA , HallMW, ClarkRS, JaffeR, CarcilloJA: Prolonged lymphopenia, lymphoid depletion, and hypoprolactinemia in children with nosocomial sepsis and multiple organ failure.J. Immunol.174, 3765–3772 (2005).
- Heidecke CD , HenslerT, WeighardtH et al.: Selective defects of T lymphocyte function in patients with lethal intraabdominal infection. Am. J. Surg.178, 288–292 (1999).
- King LE , Osati-AshtianiF, FrakerPJ: Apoptosis plays a distinct role in the loss of precursor lymphocytes during zinc deficiency in mice.J. Nutr.132, 974–979 (2002).
- Kitamura H , MorikawaH, KamonH et al.: Toll-like receptor-mediated regulation of zinc homeostasis influences dendritic cell function.Nat. Immunol.7, 971–977 (2006).
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