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Pharmacogenomics Volume 8, 2007 - Issue 10
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Research Report

Combined Glutathione S-transferase T1 and M1 Positive Genotypes Afford Protection Against Type 2 Diabetes in Japanese

Masaharu Hori1 Kumamoto University, Division of Pharmacology and Therapeutics, Graduate School of Medical and Pharmaceutical Sciences, Oe-honmachi 5-1, Kumamoto, 862–0973, Japan.View further author information
,
Kentaro Oniki1 Kumamoto University, Division of Pharmacology and Therapeutics, Graduate School of Medical and Pharmaceutical Sciences, Oe-honmachi 5-1, Kumamoto, 862–0973, Japan.View further author information
,
Kentaro Ueda1 Kumamoto University, Division of Pharmacology and Therapeutics, Graduate School of Medical and Pharmaceutical Sciences, Oe-honmachi 5-1, Kumamoto, 862–0973, Japan.View further author information
,
Shuji Goto1 Kumamoto University, Division of Pharmacology and Therapeutics, Graduate School of Medical and Pharmaceutical Sciences, Oe-honmachi 5-1, Kumamoto, 862–0973, Japan.View further author information
,
Shuichi Mihara2 Japanese Red Cross Kumamoto Health Care Center, Nagamine-minami 2-1-1, Kumamoto, 861-8528, JapanView further author information
,
Toru Marubayashi2 Japanese Red Cross Kumamoto Health Care Center, Nagamine-minami 2-1-1, Kumamoto, 861-8528, JapanView further author information
&
Kazuko Nakagawa1 Kumamoto University, Division of Pharmacology and Therapeutics, Graduate School of Medical and Pharmaceutical Sciences, Oe-honmachi 5-1, Kumamoto, 862–0973, Japan.Correspondence[email protected]
View further author information
 show all
Pages 1307-1314 | Published online: 02 Nov 2007

Bibliography

  • Shoelson SE , LeeJ, GoldfineAB: Inflammation and insulin resistance.J. Clin. Invest.116, 1793–1801 (2006).
  • Evans JL , GoldfineID, MadduxBA, GrodskyGM: Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of Type 2 diabetes.Endocr. Rev.23, 599–622 (2002).
  • Ceriello A , MotzE: Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited.Arterioscler. Thromb. Vasc. Biol.24, 816–823 (2004).
  • Hu FB , StampferMJ, HaffnerSM, SolomonCG, WillettWC, MansonJE: Elevated risk of cardiovascular disease prior to clinical diagnosis of Type 2 diabetes.Diabetes Care25, 1129–1134 (2002).
  • Booth GL , KapralMK, FungK, TuJV: Recent trends in cardiovascular complications among men and women with and without diabetes.Diabetes Care29, 32–37 (2006).
  • Danaei G , LawesCM, Vander Hoorn S, Murray CJ, Ezzati M: Global and regional mortality from ischaemic heart disease and stroke attributable to higher-than-optimum blood glucose concentration: comparative risk assessment. Lancet368, 1651–1659 (2006).
  • Stern MP : Diabetes and cardiovascular disease. The “common soil” hypothesis.Diabetes44, 369–374 (1995).
  • Hayes JD , FlanaganJU, JowseyIR: Glutathione transferases.Annu. Rev. Pharmacol. Toxicol.45, 51–88 (2005).
  • Hayes JD , StrangeRC: Glutathione S-transferase polymorphisms and their biological consequences.Pharmacology61, 154–166 (2000).
  • Cotton SC , SharpL, LittleJ, BrocktonN: Glutathione S-transferase polymorphisms and colorectal cancer: a HuGE review.Am. J. Epidemiol.151, 7–32 (2000).
  • Wiencke JK , KelseyKT, LamelaRA, ToscanoWA Jr: Human glutathione S-transferase deficiency as a marker of susceptibility to epoxide-induced cytogenetic damage. Cancer Res.50, 1585–1590 (1990).
  • Foy CG , BellRA, FarmerDF, GoffDC Jr, Wagenknecht LE: Smoking and incidence of diabetes among U.S. adults: findings from the Insulin Resistance Atherosclerosis Study. Diabetes Care28, 2501–2507 (2005).
  • Eliasson B : Cigarette smoking and diabetes.Prog. Cardiovasc. Dis.45, 405–413 (2003).
  • Doney AS , LeeS, LeeseGP, MorrisAD, PalmerCN: Increased cardiovascular morbidity and mortality in Type 2 diabetes is associated with the glutathione S transferase theta-null genotype: a Go-DARTS study.Circulation111, 2927–2934 (2005).
  • Hayek T , StephensJW, HubbartCS et al.: A common variant in the glutathione S transferase gene is associated with elevated markers of inflammation and lipid peroxidation in subjects with diabetes mellitus.Atherosclerosis184, 404–412 (2006).
  • Wang G , ZhangL, LiQ: Genetic polymorphisms of GSTT1, GSTM1, and NQO1 genes and diabetes mellitus risk in Chinese population.Biochem. Biophys. Res. Commun.341, 310–313 (2006).
  • Yalin S , HatungilR, TamerL et al.: Glutathione S-transferase gene polymorphisms in Turkish patients with diabetes mellitus. Cell Biochem. Funct.25(5), 509–513 (2007)
  • Fujita H , NaritaT, MeguroH et al.: No association of glutathione S-transferase M1 gene polymorphism with diabetic nephropathy in Japanese Type 2 diabetic patients.Ren. Fail.22, 479–486 (2000).
  • Yang Y , KaoMT, ChangCC et al.: Glutathione S-transferase T1 deletion is a risk factor for developing end-stage renal disease in diabetic patients.Int. J. Mol. Med.14, 855–859 (2004).
  • Bekris LM , ShephardC, PetersonM et al.: Glutathione-S-transferase M1 and T1 polymorphisms and associations with Type 1 diabetes age-at-onset.Autoimmunity38, 567–575 (2005).
  • Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care20, 1183–1197 (1997).
  • Ueda K , IshitsuT, SeoT et al.: Glutathione S-transferase M1 null genotype as a risk factor for carbamazepine-induced mild hepatotoxicity.Pharmacogenomics8, 435–442 (2007).
  • Abu-Amero KK , Al-BoudariOM, MohamedGH, DzimiriN: T null and M null genotypes of the glutathione S-transferase gene are risk factor for CAD independent of smoking.BMC Med. Genet.7, 38 (2006).
  • Tamer L , ErcanB, CamsariA et al.: Glutathione S-transferase gene polymorphism as a susceptibility factor in smoking-related coronary artery disease.Basic. Res. Cardiol.99, 223–229 (2004).
  • Masetti S , BottoN, ManfrediS et al.: Interactive effect of the glutathione S-transferase genes and cigarette smoking on occurrence and severity of coronary artery risk.J. Mol. Med.81, 488–494 (2003).
  • Miller EA , PankowJS, MillikanRC et al.: Glutathione-S-transferase genotypes, smoking, and their association with markers of inflammation, hemostasis, and endothelial function: the Atherosclerosis Risk In Communities (ARIC) study.Atherosclerosis171, 265–272 (2003).
  • Townsend DM , TewKD, TapieroH: The importance of glutathione in human disease.Biomed. Pharmacother.57, 145–155 (2003).
  • Morita H , IkedaH, HaramakiN, Eguchi H, Imaizumi T: Only two-week smoking cessation improves platelet aggregability and intraplatelet redox imbalance of long-term smokers. J. Am. Coll. Cardiol.45, 589–594 (2005).
  • Eliasson B , AttvallS, TaskinenMR, Smith U: Smoking cessation improves insulin sensitivity in healthy middle-aged men. Eur. J. Clin. Invest.27, 450–456 (1997).
  • Pemble S , SchroederKR, SpencerSR et al.: Human glutathione S-transferase θ (GSTT1): cDNA cloning and the characterization of a genetic polymorphism.Biochem. J.300 (Pt 1), 271–276 (1994).
  • Wang L , GrovesMJ, HepburnMD, Bowen DT: Glutathione S-transferase enzyme expression in hematopoietic cell lines implies a differential protective role for T1 and A1 isoenzymes in erythroid and for M1 in lymphoid lineages. Haematologica85, 573–579 (2000).
  • Tsantes AE , BonovasS, TravlouA, Sitaras NM: Redox imbalance, macrocytosis, and RBC homeostasis. Antioxid. Redox Signal.8, 1205–1216 (2006).
  • Straface E , RivabeneR, MasellaR, Santulli M, Paganelli R, Malorni W: Structural changes of the erythrocyte as a marker of non-insulin-dependent diabetes: protective effects of N-acetylcysteine. Biochem. Biophys. Res. Commun.290, 1393–1398 (2002).
  • Sailaja YR , BaskarR, SaralakumariD: The antioxidant status during maturation of reticulocytes to erythrocytes in Type 2 diabetics.Free Radic. Biol. Med.35, 133–139 (2003).

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