Bibliography
- Wogan GN , HechtSS, FeltonJS, ConneyAH, LoebLA: Environmental and chemical carcinogenesis.Semin. Cancer Biol.14(6) , 473–486 (2004).
- Schiffman M , CastlePE, JeronimoJ, RodriguezAC, WacholderS: Human papillomavirus and cervical cancer.Lancet370(9590) , 890–907 (2007).
- DePinho RA : The age of cancer.Nature408(6809) , 248–254 (2000).
- Knudson AG Jr: Mutation and cancer: statistical study of retinoblastoma. Proc. Natl Acad. Sci. USA68(4) , 820–823 (1971).
- Zhu L : Tumour suppressor retinoblastoma protein Rb: a transcriptional regulator.Eur. J. Cancer41(16) , 2415–2427 (2005).
- Li FP , FraumeniJF Jr: Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome? Ann. Intern. Med.71(4) , 747–752 (1969).
- Sengupta S , HarrisCC: p53: traffic cop at the crossroads of DNA repair and recombination.Nat. Rev. Mol. Cell Biol.6(1) , 44–55 (2005).
- Malkin D , LiFP, StrongLC et al.: Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms.Science250(4985) , 1233–1238 (1990).
- Li FP , FraumeniJF Jr, Mulvihill JJ et al.: A cancer family syndrome in twenty-four kindreds. Cancer Res.48(18) , 5358–5362 (1988).
- Wang W : Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins.Nat. Rev. Genet.8(10) , 735–748 (2007).
- Wooster R , NeuhausenSL, MangionJ et al.: Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12–13.Science265(5181) , 2088–2090 (1994).
- Hall JM , LeeMK, NewmanB et al.: Linkage of early-onset familial breast cancer to chromosome 17q21.Science250(4988) , 1684–1689 (1990).
- The International HapMap Consortium: The International HapMap Project. Nature426(6968) , 789–796 (2003).
- Eichler EE , NickersonDA, AltshulerD et al.: Completing the map of human genetic variation.Nature447(7141) , 161–165 (2007).
- Packer BR , YeagerM, BurdettL et al.: SNP500Cancer: a public resource for sequence validation, assay development, and frequency analysis for genetic variation in candidate genes.Nucleic Acids Res.34(Database issue) , D617–D621 (2006).
- Stram DO : Tag SNP selection for association studies.Genet. Epidemiol.27(4) , 365–374 (2004).
- de Bakker PI , YelenskyR, Pe‘erI, GabrielSB, DalyMJ, AltshulerD: Efficiency and power in genetic association studies.Nat.Genet.37(11) , 1217–1223 (2005).
- Savage SA , AbnetCC, MarkSD et al.: Variants of the IL8 and IL8RB genes and risk for gastric cardia adenocarcinoma and esophageal squamous cell carcinoma.Cancer Epidemiol. Biomarkers Prev.13(12) , 2251–2257 (2004).
- Lee WP , TaiDI, LanKH et al.: The -251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese population.Clin. Cancer Res.11(18) , 6431–6441 (2005).
- Ohyauchi M , ImataniA, YonechiM et al.: The polymorphism interleukin 8 -251 A/T influences the susceptibility of Helicobacter pylorirelated gastric diseases in the Japanese population.Gut54(3) , 330–335 (2005).
- Taguchi A , OhmiyaN, ShiraiK et al.: Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan.Cancer Epidemiol. Biomarkers Prev.14(11 Pt 1) , 2487–2493 (2005).
- Savage SA , HouL, LissowskaJ et al.: Interleukin-8 polymorphisms are not associated with gastric cancer risk in a Polish population.Cancer Epidemiol. Biomarkers Prev.15(3) , 589–591 (2006).
- Garza-Gonzalez E , Bosques-PadillaFJ, Mendoza-IbarraSI, Flores-GutierrezJP, Maldonado-GarzaHJ, Perez-PerezGI: Assessment of the toll-like receptor 4 Asp299Gly, Thr399Ile and interleukin-8 -251 polymorphisms in the risk for the development of distal gastric cancer.BMC. Cancer7 , 70 (2007).
- Hirschhorn JN , LohmuellerK, ByrneE, HirschhornK: A comprehensive review of genetic association studies.Genet. Med.4(2) , 45–61 (2002).
- Lohmueller KE , PearceCL, PikeM, LanderES, HirschhornJN: Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease.Nat. Genet.33(2) , 177–182 (2003).
- Dong LM , PotterJD, WhiteE, UlrichCM, CardonLR, PetersU: Genetic susceptibility to cancer: the role of polymorphisms in candidate genes.JAMA299(20) , 2423–2436 (2008).
- Wacholder S , ChanockS, Garcia-ClosasM, El Ghormli L, Rothman N: Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J. Natl Cancer Inst.96(6) , 434–442 (2004).
- Khoury MJ , LittleJ, GwinnM, IoannidisJP: On the synthesis and interpretation of consistent but weak gene-disease associations in the era of genome-wide association studies.Int. J. Epidemiol.36(2) , 439–445 (2007).
- Rebbeck TR , MartinezME, SellersTA, ShieldsPG, WildCP, PotterJD: Genetic variation and cancer: improving the environment for publication of association studies.Cancer Epidemiol. Biomarkers Prev.13(12) , 1985–1986 (2004).
- Boffetta P , McLaughlinJK, La Vecchia C, Tarone RE, Lipworth L, Blot WJ: False-positive results in cancer epidemiology: a plea for epistemological modesty. J. Natl Cancer Inst.100(14) , 988–995 (2008).
- Ioannidis JP , GwinnM, LittleJ et al.: A road map for efficient and reliable human genome epidemiology.Nat. Genet.38(1) , 3–5 (2006).
- Hunter DJ , ThomasG, HooverRN, ChanockSJ: Scanning the horizon: what is the future of genome-wide association studies in accelerating discoveries in cancer etiology and prevention?Cancer Causes Control18(5) , 479–484 (2007).
- Amos CI : Successful design and conduct of genome-wide association studies.Hum. Mol. Genet.16(Spec No. 2) , R220–R225 (2007).
- Hunter DJ , KraftP: Drinking from the fire hose – statistical issues in genome wide association studies.N. Engl. J. Med.357(5) , 436–439 (2007).
- Zanke BW , GreenwoodCM, RangrejJ et al.: Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24.Nat. Genet.39(8) , 989–994 (2007).
- Yeager M , OrrN, HayesRB et al.: Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.Nat. Genet.39(5) , 645–649 (2007).
- Schumacher FR , FeigelsonHS, CoxDG et al.: A common 8q24 variant in prostate and breast cancer from a large nested case-control study.Cancer Res.67(7) , 2951–2956 (2007).
- Gudmundsson J , SulemP, ManolescuA et al.: Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.Nat. Genet.39(5) , 631–637 (2007).
- Eeles RA , Kote-JaraiZ, GilesGG et al.: Multiple newly identified loci associated with prostate cancer susceptibility.Nat. Genet.40(3) , 316–321 (2008).
- Ghoussaini M , SongH, KoesslerT et al.: Multiple loci with different cancer specificities within the 8q24 gene desert.J. Natl Cancer Inst.100(13) , 962–966 (2008).
- Hunter DJ , KraftP, JacobsKB et al.: A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.Nat. Genet.39(7) , 870–874 (2007).
- Easton DF , PooleyKA, DunningAM et al.: Genome-wide association study identifies novel breast cancer susceptibility loci.Nature447(7148) , 1087–1093 (2007).
- Maris JM , MosseYP, BradfieldJP et al.: Chromosome 6p22 locus associated with clinically aggressive neuroblastoma.N. Engl. J. Med.358(24) , 2585–2593 (2008).
- Li JZ , AbsherDM, TangH et al.: Worldwide human relationships inferred from genome-wide patterns of variation.Science319(5866) , 1100–1104 (2008).
- Hughes AL , WelchR, PuriV et al.: Genome-wide SNP typing reveals signatures of population history.Genomics92(1) , 1–8 (2008).
- Yu K , WangZ, LiQ et al.: Population substructure and control selection in genome-wide association studies.PLoS one3(7) , E2551 (2008).
- Wellcome Trust Case Control Consortium: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature447(7145) , 661–678 (2007).
- Pharoah PD , AntoniouAC, EastonDF, PonderBA: Polygenes, risk prediction, and targeted prevention of breast cancer.N. Engl. J. Med.358(26) , 2796–2803 (2008).
- Savage SA , GreeneMH: The evidence for prostate cancer risk loci at 8q24 grows stronger.J. Natl Cancer Inst.99(20) , 1499–1501 (2007).
- Wang L , McDonnellSK, SlusserJP et al.: Two common chromosome 8q24 variants are associated with increased risk for prostate cancer.Cancer Res.67(7) , 2944–2950 (2007).
- Zheng SL , SunJ, ChengY et al.: Association between two unlinked loci at 8q24 and prostate cancer risk among European Americans.J. Natl Cancer Inst.99(20) , 1525–1533 (2007).
- Zheng SL , SunJ, WiklundF et al.: Cumulative association of five genetic variants with prostate cancer.N. Engl J. Med.358(9) , 910–919 (2008).
- Coates RJ , KhouryMJ, GwinnM: Five genetic variants associated with prostate cancer.N. Engl. J. Med.358(25) , 2738 (2008).
- Gelmann EP : Complexities of prostate-cancer risk.N. Engl. J. Med.358(9) , 961–963 (2008).
- Eisinger F : Five genetic variants associated with prostate cancer.N. Engl. J. Med.358(25) , 2740–2741 (2008).
- Gartner CE , BarendregtJJ, HallWD: Five genetic variants associated with prostate cancer.N. Engl. J. Med.358(25) , 2738–2739 (2008).
- Janssens AC , van Duijn CM: Five genetic variants associated with prostate cancer. N. Engl. J. Med.358(25) , 2739 (2008).
- Severi G , ByrnesGB, HopperJL: Five genetic variants associated with prostate cancer.N. Engl. J. Med.358(25) , 2739–2740 (2008).
- Thorat MA : Five genetic variants associated with prostate cancer.N. Engl. J. Med.358(25) , 2740 (2008).
- Vickers A , LiljaH, ScardinoP: Five genetic variants associated with prostate cancer.N. Engl. J. Med.358(25) , 2740 (2008).
- Hunter DJ , KhouryMJ, DrazenJM: Letting the genome out of the bottle – will we get our wish?N. Engl. J. Med.358(2) , 105–107 (2008).
- Greene MH , PiedmonteM, AlbertsD et al.: A prospective study of risk-reducing salpingo-oophorectomy and longitudinal CA–125 screening among women at increased genetic risk of ovarian cancer: design and baseline characteristics: a Gynecologic Oncology Group study.Cancer Epidemiol. Biomarkers Prev.17(3) , 594–604 (2008).
- Khoury MJ , GwinnM, YoonPW, DowlingN, MooreCA, BradleyL: The continuum of translation research in genomic medicine: how can we accelerate the appropriate integration of human genome discoveries into health care and disease prevention?Genet. Med.9(10) , 665–674 (2007).
- Easton DF , PooleyKA, DunningAM et al.: Genome-wide association study identifies novel breast cancer susceptibility loci.Nature447(7148) , 1087–1093 (2007).
- Gold B , KirchhoffT, StefanovS et al.: Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.Proc. Natl Acad. Sci. USA105(11) , 4340–4345 (2008).
- Stacey SN , ManolescuA, SulemP et al.: Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer.Nat. Genet.39(7) , 865–869 (2007).
- Tomlinson I , WebbE, Carvajal-CarmonaL et al.: A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21.Nat. Genet.39(8) , 984–988 (2007).
- Tomlinson IP , WebbE, Carvajal-CarmonaL et al.: A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10.14 and 8q23.3.Nat. Genet.40(5) , 623–630 (2008).
- Broderick P , Carvajal-CarmonaL, PittmanAM et al.: A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk.Nat. Genet.39(11) , 1315–1317 (2007).
- Tenesa A , FarringtonSM, PrendergastJG et al.: Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.Nat. Genet.40(5) , 631–637 (2008).
- Sakamoto H , YoshimuraK, SaekiN et al.: Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.Nat. Genet.40(6) , 730–740 (2008).
- Hung RJ , McKayJD, GaborieauV et al.: A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.Nature452(7187) , 633–637 (2008).
- Thorgeirsson TE , GellerF, SulemP et al.: A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.Nature452(7187) , 638–642 (2008).
- Amos CI , WuX, BroderickP et al.: Genome‑wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.Nat. Genet.40(5) , 616–622 (2008).
- Brown KM , MacgregorS, MontgomeryGW et al.: Common sequence variants on 20q11.22 confer melanoma susceptibility.Nat. Genet.40(7) , 817–818 (2008).
- Gudmundsson J , SulemP, SteinthorsdottirV et al.: Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against Type 2 diabetes.Nat. Genet.39(8) , 977–983 (2007).
- Gudmundsson J , SulemP, RafnarT et al.: Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer.Nat. Genet.40(3) , 281–283 (2008).
- Nam RK , ZhangWW, LoblawDA et al.: A genome-wide association screen identifies regions on chromosomes 1q25 and 7p21 as risk loci for sporadic prostate cancer.Prostate Cancer Prostatic. Dis.11(3) , 241–246 (2007).
- Duggan D , ZhengSL, KnowltonM et al.: Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP.J. Natl Cancer Inst.99(24) , 1836–1844 (2007).
- Thomas G , JacobsKB, YeagerM et al.: Multiple loci identified in a genome-wide association study of prostate cancer.Nat. Genet.40(3) , 310–315 (2008).
▪ Websites
- SeattleSNPs: Variation discovery resource http://pga.gs.washington.edu
- 1000 Genomes www.1000genomes.org
- Genetic Association Database http://geneticassociationdb.nih.gov
- Genome-Wide Association Studies, NIH policies http://grants.nih.gov/grants/gwas/index.htm
- db GaP: GENOTYPE and PHENOTYPE www.ncbi.nlm.nih.gov/entrez/query/Gap/gap_tmpl/about.html