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Review

Genetic Markers of Vascular Aging

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Pages 453-465 | Published online: 05 Nov 2007

Bibliography

  • Zieman SJ , MelenovskyV, KassDA: Mechanisms, pathophysiology, and therapy of arterial stiffness.Arterioscler. Thromb. Vasc. Biol.25(5), 932–943 (2005).
  • Lewington S , ClarkeR, QizilbashN, PetoR, CollinsR: Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet360(9349), 1903–1913 (2002).
  • Kullo IJ , MalikAR: Arterial ultrasonography and tonometry as adjuncts to cardiovascular risk stratification.J. Am. Coll. Cardiol.49(13), 1413–1426 (2007).
  • Blacher J , StaessenJA, GirerdXet al.: Pulse pressure not mean pressure determines cardiovascular risk in older hypertensive patients. Arch. Intern. Med.160(8), 1085–1089 (2000).
  • Sorof JM : Prevalence and consequence of systolic hypertension in children.Am. J. Hypertens.15(Suppl. 2, Pt 2) , 57S–60S (2002).
  • Saeki A , RecchiaF, KassDA: Systolic flow augmentation in hearts ejecting into a model of stiff aging vasculature. Influence on myocardial perfusion-demand balance.Circ. Res.76(1), 132–141 (1995).
  • Pannier BM , AvolioAP, HoeksA, ManciaG, TakazawaK: Methods and devices for measuring arterial compliance in humans. Am. J. Hypertens.15(8), 743–753 (2002).
  • Safar ME , LevyBI, Struijker-BoudierH: Current perspectives on arterial stiffness and pulse pressure in hypertension and cardiovascular diseases.Circulation107(22), 2864–2869 (2003).
  • Safar ME , BoudierHS: Vascular development, pulse pressure, and the mechanisms of hypertension.Hypertension46(1), 205–209 (2005).
  • Oliver JJ , WebbDJ: Noninvasive assessment of arterial stiffness and risk of atherosclerotic events.Arterioscler. Thromb. Vasc. Biol.23(4), 554–566 (2003).
  • Laurent S , CockcroftJ, Van BortelLet al.: Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur. Heart J.27(21), 2588–2605 (2006).
  • Willum-Hansen T , StaessenJA, Torp-PedersenCet al.: Prognostic value of aortic pulse wave velocity as index of arterial stiffness in the general population. Circulation113(5), 664–670 (2006).
  • Mattace-Raso FU , van der CammenTJ, HofmanAet al.: Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation113(5), 657–663 (2006).
  • Weber T , AuerJ, LammG, O‘RourkeMF, EberB: Arterial stiffness, wave reflections, and the risk of coronary artery disease.Circulation109(2), 184–189 (2004).
  • London GM , BlacherJ, PannierB, GuérinAP, MarchaisSJ, SafarME: Arterial wave reflections and survival in end-stage renal failure. Hypertension38(3), 434–438 (2001).
  • McEniery CM , Yasmin, HallIRet al.: Normal vascular aging: differential effects on wave reflection and aortic pulse wave velocity: the Anglo-Cardiff Collaborative Trial (ACCT). J. Am. Coll. Cardiol.46(9), 1753–1760 (2005).
  • Wojciechowska W , StaessenJA, NawrotTet al.: Reference values in white Europeans for the arterial pulse wave recorded by means of the SphygmoCor device. Hypertens. Res.29(7), 475–483 (2006).
  • Adeyemo AA , OmotadeOO, RotimiCNet al.: Heritability of blood pressure in Nigerian families. J. Hypertens.20(5), 859–863 (2002).
  • Snieder H , HarshfieldGA, TreiberFA: Heritability of blood pressure and hemodynamics in African– and European–American youth.Hypertension41(6), 1196–1201 (2003).
  • Atwood LD , SamollowPB, HixsonJE, SternMP, MacCluerJW: Genome-wide linkage analysis of pulse pressure in Mexican Americans.Hypertension37(Suppl. 2 Pt 2) , 425–428 (2001).
  • Camp NJ , HopkinsPN, HasstedtSJet al.: Genome-wide multipoint parametric linkage analysis of pulse pressure in large, extended Utah pedigrees. Hypertension42(3), 322–328 (2003).
  • Bielinski SJ , LynchAI, MillerMBet al.: Genome-wide linkage analysis for loci affecting pulse pressure: the Family Blood Pressure Program. Hypertension46(6), 1286–1293 (2005).
  • Williams JT , DuggiralaR, BlangeroJ: Statistical properties of a variance components method for quantitative trait linkage analysis in nuclear families and extended pedigrees.Genet. Epidemiol.14(6), 1065–1070 (1997).
  • Hsu FC , ZaccaroDJ, LangeLAet al.: The impact of pedigree structure on heritability estimates for pulse pressure in three studies. Hum. Hered.60(2), 63–72 (2005).
  • Bochud M , BovetP, ElstonRCet al.: High heritability of ambulatory blood pressure in families of East African descent. Hypertension45(3), 445–450 (2005).
  • DeStefano AL , LarsonMG, MitchellGFet al.: Genome-wide scan for pulse pressure in the National Heart, Lung and Blood Institute‘s Framingham Heart Study. Hypertension44(2), 152–155 (2004).
  • Medley TL , ColeTJ, DartAM, GatzkaCD, KingwellBA: Matrix metalloproteinase-9 genotype influences large artery stiffness through effects on aortic gene and protein expression.Arterioscler. Thromb. Vasc. Biol.24(8), 1479–1484 (2004).
  • Cwynar M , StaessenJA, TichaMet al.: Epistatic interaction between α- and γ-adducin influences peripheral and central pulse pressures in white Europeans. J. Hypertens.23(5), 961–969 (2005).
  • Powell JT , TurnerRJ, HenneyAM, MillerGJ, HumphriesSE: An association between arterial pulse pressure and variation in the fibrillin-1 gene. Heart78(4), 396–398 (1997).
  • Medley TL , ColeTJ, GatzkaCDet al.: Fibrillin-1 genotype is associated with aortic stiffness and disease severity in patients with coronary artery disease. Circulation105(7), 810–815 (2002).
  • Powell JT , TurnerRJ, SianM, DebassoR, LanneT: Influence of fibrillin-1 genotype on the aortic stiffness in men.J. Appl. Physiol.99(3), 1036–1040 (2005).
  • Yasmin O ‘Shaughnessy KM, McEniery CM, Cockcroft JR, Wilkinson IB: Genetic variation in fibrillin-1 gene is not associated with arterial stiffness in apparently healthy individuals. J. Hypertens.24(3), 499–502 (2006).
  • Mitchell GF , GuoCY, KathiresanSet al.: Vascular stiffness and genetic variation at the endothelial nitric oxide synthase locus. The Framingham Heart Study. Hypertension49(6), 1285–1290 (2007).
  • Mourad JJ , DucailarG, RudnickiAet al.: Age-related increase of pulse pressure and gene polymorphisms in essential hypertension: a preliminary study. J. Renin Angiotensin Aldosterone Syst.3(2), 109–115 (2002).
  • Safar ME , LajemiM, RudnichiA, AsmarR, BenetosA: Angiotensin-converting enzyme D/I gene polymorphism and age-related changes in pulse pressure in subjects with hypertension.Arterioscler. Thromb. Vasc. Biol.24(4), 782–786 (2004).
  • Sayed-Tabatabaei FA , van RijnMJ, SchutAFet al.: Heritability of the function and structure of the arterial wall: findings of the Erasmus Rucphen Family (ERF) study. Stroke36(11), 2351–2356 (2005).
  • Mitchell GF , DeStefanoAL, LarsonMGet al.: Heritability and a genome-wide linkage scan for arterial stiffness, wave reflection, and mean arterial pressure: the Framingham Heart Study. Circulation112(2), 194–199 (2005).
  • Benetos A , GautierS, RicardSet al.: Influence of angiotensin-converting enzyme and angiotensin II type 1 receptor gene polymorphisms on aortic stiffness in normotensive and hypertensive patients. Circulation94(4), 698–703 (1996).
  • Lajemi M , LabatC, GautierSet al.: Angiotensin II type 1 receptor-153A/G and 1166A/C gene polymorphisms and increase in aortic stiffness with age in hypertensive subjects. J. Hypertens.19(3), 407–413 (2001).
  • Gardier S , VincentM, LantelmePet al.: A1166C polymorphism of angiotensin II type 1 receptor, blood pressure and arterial stiffness in hypertension. J. Hypertens.22(11), 2135–2142 (2004).
  • Taniwaki H , KawagishiT, EmotoMet al.: Association of ACE gene polymorphism with arterial stiffness in patients with type 2 diabetes. Diabetes Care22(11), 1858–1864 (1999).
  • Mattace-Raso FU , van der CammenTJ, Sayed-TabatabaeiFAet al.: Angiotensin-converting enzyme gene polymorphism and common carotid stiffness. The Rotterdam study. Atherosclerosis174(1), 121–126 (2004).
  • Pojoga L , GautierS, BlancHet al.: Genetic determination of plasma aldosterone levels in essential hypertension. Am. J. Hypertens.11(7), 856–860 (1998).
  • Yasmin M cEniery CM, O‘Shaughnessy KM et al.: Variation in the human matrix metalloproteinase-9 gene is associated with arterial stiffness in healthy individuals. Arterioscler. Thromb. Vasc. Biol.26(8), 1799–1805 (2006).
  • Lajemi M , GautierS, PoirierOet al.: Endothelin gene variants and aortic and cardiac structure in never-treated hypertensives. Am. J. Hypertens.14(8 Pt 1) , 755–760 (2001).
  • Nurnberger J , Opazo SaezA, MitchellAet al.: The T-allele of the C825Tpolymorphism is associated with higher arterial stiffness in young healthy males. J. Hum. Hypertens.18(4), 267–271 (2004).
  • Snieder H , HaywardCS, PerksUet al.: Heritability of central systolic pressure augmentation: a twin study. Hypertension35(2), 574–579 (2000).
  • North KE , MacCluerJW, DevereuxRBet al.: Heritability of carotid artery structure and function: The Strong Heart Family Study. Arterioscler. Thromb. Vasc. Biol.22(10), 1698–1703 (2002).
  • Wojciechowska W , StaessenJA, StolarzKet al.: Association of peripheral and central arterial wave reflections with the CYP11B2-344C allele and sodium excretion. J. Hypertens.22(12), 2311–2319 (2004).
  • Juo SH , RundekT, LinHFet al.: Heritability of carotid artery distensibility in Hispanics: the Northern Manhattan Family Study. Stroke36(11), 2357–2361 (2005).
  • Medley TL , KingwellBA, GatzkaCD, PillayP, ColeTJ: Matrix metalloproteinase-3 genotype contributes to age-related aortic stiffening through modulation of gene and protein expression.Circ. Res.92(11), 1254–1261 (2003).
  • Bozec E , LacolleyP, BergayaSet al.: Arterial stiffness and angiotensinogen gene in hypertensive patients and mutant mice. J. Hypertens.22(7), 1299–1307 (2004).
  • Balkestein EJ , StaessenJA, WangJGet al.: Carotid and femoral artery stiffness in relation to three candidate genes in a white population. Hypertension38(5), 1190–1197. (2001).
  • Jondeau G , BoutouyrieP, LacolleyPet al.: Central pulse pressure is a major determinant of ascending aorta dilation in Marfan syndrome. Circulation99(20), 2677–2681 (1999).
  • Aggoun Y , SidiD, LevyBIet al.: Mechanical properties of the common carotid artery in Williams syndrome. Heart84(3), 290–293 (2000).
  • Boutouyrie P , GermainDP, FiessingerJNet al.: Increased carotid wall stress in vascular Ehlers–Danlos syndrome. Circulation109(12), 1530–1535 (2004).
  • Hopper JL : Heritability. In:Biostatistical Genetics and Genetic Epidemiology. Elston RS, Olsen J, Palmer I (Eds). Wiley, Chichester, UK, 371–372 (2002).
  • Xiang AH , AzenSP, BuchananTAet al.: Heritability of subclinical atherosclerosis in Latino families ascertained through a hypertensive parent. Arterioscler. Thromb. Vasc. Biol.22(5), 843–848 (2002).
  • Lander E , KruglyakL: Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results.Nat. Genet.11(3), 241–247 (1995).
  • Williams GH : Genetic approaches to understanding the pathophysiology of complex human traits.Kidney Int.46(6), 1550–1553 (1994).
  • Risch NJ , ZhangH: Mapping quantitative trait loci with extreme discordant sib pairs: sampling considerations.Am. J. Hum. Genet.58(4), 836–843 (1996).
  • Peltonen L , McKusickVA: Genomics and medicine. Dissecting human disease in the postgenomic era.Science291(5507), 1224–1229 (2001).
  • Palmer LJ , CardonLR: Shaking the tree: mapping complex disease genes with linkage disequilibrium.Lancet366(9492), 1223–1234 (2005).
  • Nichols WW , O‘RourkeM: McDonald’s Blood Flow in Arteries: Theoretical, Experimental and Clinical Principles (4th Edition). Arnold, London, UK, 107–135 (1998).
  • Oh JK , SewardJB, TajikAJ: The Echo Manual (3rd Edition). Lippincott Williams & Wilkins, Philadelphia, USA, 383–389 (2006).
  • Xu X , RogusJJ, TerwedowHAet al.: An extreme-sib-pair genome scan for genes regulating blood pressure. Am. J. Hum. Genet.64(6), 1694–1701 (1999).
  • Rice T , RankinenT, ProvinceMAet al.: Genome-wide linkage analysis of systolic and diastolic blood pressure: the Quebec Family Study. Circulation102(16), 1956–1963 (2000).
  • Luft FC : Molecular genetics of human hypertension.J. Hypertens.16(12 Pt 2) , 1871–1878 (1998).
  • DeStefano AL , BaldwinCT, BurzstynMet al.: Autosomal dominant orthostatic hypotensive disorder maps to chromosome 18q. Am. J. Hum. Genet.63(5), 1425–1430 (1998).
  • Wu DA , BuX, WardenCHet al.: Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22. J. Clin. Invest.97(9), 2111–2118 (1996).
  • Xu X , YangJ, RogusJet al.: Mapping of a blood pressure quantitative trait locus to chromosome 15q in a Chinese population. Hum. Mol. Genet.8(13), 2551–2555 (1999).
  • Levy D , DeStefanoAL, LarsonMGet al.: Evidence for a gene influencing blood pressure on chromosome 17. Genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the Framingham Heart Study. Hypertension36(4), 477–483 (2000).
  • Kristjansson K , ManolescuA, KristinssonAet al.: Linkage of essential hypertension to chromosome 18q. Hypertension39(6), 1044–1049 (2002).
  • Jacobs KB , Gray-McGuireC, CartierKC, ElstonRC: Genome-wide linkage scan for genes affecting longitudinal trends in systolic blood pressure.BMC Genet.4(Suppl. 1) , S82 (2003).
  • Cooper RS , LukeA, ZhuXet al.: Genome scan among Nigerians linking blood pressure to chromosomes 2, 3, and 19. Hypertension40(5), 629–633 (2002).
  • Perola M , KainulainenK, PajukantaPet al.: Genome-wide scan of predisposing loci for increased diastolic blood pressure in Finnish siblings. J. Hypertens.18(11), 1579–1585 (2000).
  • Lacolley P , GautierS, PoirierOet al.: Nitric oxide synthase gene polymorphisms, blood pressure and aortic stiffness in normotensive and hypertensive subjects. J. Hypertens.16(1), 31–35 (1998).
  • Hanon O , LuongV, MouradJJet al.: Aging, carotid artery distensibility, and the Ser422Gly elastin gene polymorphism in humans. Hypertension38(5), 1185–1189 (2001).
  • Chen W , SrinivasanSR, BondMGet al.: Nitric oxide synthase gene polymorphism (G894T) influences arterial stiffness in adults: The Bogalusa Heart Study. Am. J. Hypertens.17(7), 553–559 (2004).
  • De Paepe A , DevereuxRB, DietzHC, HennekamRC, PyeritzRE: Revised diagnostic criteria for the Marfan syndrome.Am. J. Med. Genet.62(4), 417–426 (1996).
  • Tsipouras P , Del MastroR, SarfaraziMet al.: Genetic linkage of the Marfan syndrome, ectopia lentis, and congenital contractural arachnodactyly to the fibrillin genes on chromosomes 15 and 5. The International Marfan Syndrome Collaborative Study. N. Engl. J. Med.326(14), 905–909 (1992).
  • Morris CA , DemseySA, LeonardCO, DiltsC, BlackburnBL: Natural history of Williams syndrome: physical characteristics. J. Pediatr.113(2), 318–326 (1988).
  • Beighton P , De PaepeA, SteinmannB, TsipourasP, WenstrupRJ: Ehlers–Danlos syndromes: revised nosology, Villefranche, 1997. Ehlers–Danlos National Foundation (USA) and Ehlers–Danlos Support Group (UK). Am. J. Med. Genet.77(1), 31–37 (1998).
  • Coucke PJ , WillaertA, WesselsMWet al.: Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome. Nat. Genet.38(4), 452–457 (2006).
  • Coucke PJ , WesselsMW, Van AckerPet al.: Homozygosity mapping of a gene for arterial tortuosity syndrome to chromosome 20q13. J. Med. Genet.40(10), 747–751 (2003).
  • Eriksson M , BrownWT, GordonLBet al.: Recurrent de novo point mutations in lamin-A cause Hutchinson-Gilford progeria syndrome. Nature423(6937), 293–298 (2003).

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