The Research Advances of Exosomes in Esophageal Cancer

References

• Zeng H , ZhengR, ZhangSet al. Esophageal cancer statistics in China, 2011: estimates based on 177 cancer registries. Thorac. Cancer7(2), 232–237 (2016).
   PubMed Web of Science ®Google Scholar
• Huang FL , YuSJ. Esophageal cancer: risk factors, genetic association, and treatment. Asian J. Surg.41(3). 210–215 (2018).
   PubMed Web of Science ®Google Scholar
• Zhang SW , ZhengRS, ZuoTT, ZengHM, ChenWQ, HeJ. Mortality and survival analysis of esophageal cancer in China. Zhonghua Zhong Liu Za Zhi38(9), 709–715 (2016).
   PubMedGoogle Scholar
• Chen W , ZhengR, BaadePDet al. Cancer statistics in China, 2015. CA Cancer J. Clin.66(2), 115–132 (2016).
   PubMed Web of Science ®Google Scholar
• Jing He , MingxiaZhou, XinfengChenet al. Inhibition of SALL4 reduces tumorigenicity involving epithelial-mesenchymal transition via Wnt/β-catenin pathway in esophageal squamous cell carcinoma. J. Exp. Clin. Cancer Res.35, 98 (2016).
   PubMed Web of Science ®Google Scholar
• Matsumoto Y , KanoM, AkutsuYet al. Quantification of plasma exosome is a potential prognostic marker for esophageal squamous cell carcinoma. Oncol. Rep.36(5), 2535–2543 (2016).
   PubMed Web of Science ®Google Scholar
• Whiteside TL . The potential of tumor-derived exosomes for noninvasive cancer monitoring. Expert Rev. Mol. Diagn.15(10), 1293–1310 (2015).
   PubMed Web of Science ®Google Scholar
• Kahlert C , MeloS, LueckeLet al. GPC-1 positive exosomes are ultrasensitive serum biomarkers for the non-invasive detection of early pancreatic cancer. Oncol. Res. Treat.39, 81 (2016).
   Web of Science ®Google Scholar
• Matsushita H , YangYM, PandolSJ, SekiE. Exosome migration inhibitory factor as a marker and therapeutic target for pancreatic cancer. Gastroenterology150(4), 1033–1035 (2016).
   PubMedGoogle Scholar
• Lv LL , CaoY, LiuDet al. Isolation and quantification of microRNAs from urinary exosomes/microvesicles for biomarker discovery. Int. J. Biol. Sci.9(10), 1021–1031 (2013).
   PubMed Web of Science ®Google Scholar
• Skog J , WürdingerT, van RijnSet al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat. Cell Biol.10(12), 1470–1476 (2008).
   PubMed Web of Science ®Google Scholar
• Nagata M , MutoS, HorieS. Molecular biomarkers in bladder cancer: novel potential indicators of prognosis and treatment outcomes. Dis. Markers.8205836 (2016).
   PubMed Web of Science ®Google Scholar
• Lin J , LiJ, HuangBet al. Exosomes: novel biomarkers for clinical diagnosis. Sci. World J.657086 (2015).
   Google Scholar
• Qin J , XuQ. Functions and application of exosomes. Acta Pol. Pharm.71(4), 537–543 (2014).
   PubMed Web of Science ®Google Scholar
• Milane L , SinghA, MattheolabakisG, SureshM, AmijiMM. Exosome mediated communication within the tumor microenvironment. J. Control. Rel.219, 278–294 (2015).
   PubMed Web of Science ®Google Scholar
• Segura E , AmigorenaS, ThéryC. Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses. Blood Cells Mol. Dis.35(2), 89–93 (2005).
   PubMed Web of Science ®Google Scholar
• Han Y , JiaLF, ZhengYF, LiWR. Salivary exosomes: emerging roles in systemic disease. Int. J. Biol. Sci.14(6), 633–643 (2018).
   PubMed Web of Science ®Google Scholar
• Yu SR , CaoHX, ShenB, FengJF. Tumor-derived exosomes in cancer progression and treatment failure. Oncotarget6(35), 37151–37168 (2015).
   PubMedGoogle Scholar
• Roma-Rodrigues C , FernandesAR, BaptistaPV. Exosome in tumour microenvironment: overview of the crosstalk between normal and cancer cells. Biomed. Res. Int.179486 (2014).
   PubMed Web of Science ®Google Scholar
• Zhou YY , WangLW. Progress in exosomes in human gastrointestinal tumor. Tumor35, 810–815 (2015).
   Google Scholar
• Hu MR , ChenT, YangCQ, GeBJ. Exosomes in the precision diagnosis and treatment of cancer. J. Shanghai Univ. (Nat. Sci.)23(2), 161–168 (2017).
   Google Scholar
• ExoCarta . Exosome protein, RNA and lipid database (2018). www.exocarta.org
   Google Scholar
• He CJ , ZhengSJ, LuoYJ, WangB. Exosome theranostics: biology and translational medicine. Theranostics8(1), 237–255 (2018).
   PubMed Web of Science ®Google Scholar
• Li P , FengJ, LiuYet al. Novel therapy for glioblastoma multiforme by restoring LRRC4 in tumor cells: LRRC4 inhibits tumor-infitrating regulatory T cells by cytokine and programmed cell death 1-containing exosomes. Front. Immunol.8, 1748 (2017).
   PubMed Web of Science ®Google Scholar
• Cheng L , LiuJ, LiuQet al. Exosomes from melatonin treated hepatocellularcarcinoma cells alter the immunosupression status through STAT3 pathway in macrophages. Int. J. Biol. Sci.13(6), 723–734 (2017).
   PubMed Web of Science ®Google Scholar
• Mu C , ZhangX, WangLet al. Enhanced suppression of polyclonal CD8+25+ regulatory T cells via exosomal arming of antigen-specific peptide/MHC complexes. J. Leukoc. Biol.101(5), 1221–1231 (2017).
   PubMed Web of Science ®Google Scholar
• Szajnik M , CzystowskaM, SzczepanskiMJ, MandapathilM, WhitesideTL. Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg). PLoS ONE5(7), e11469 (2010).
   PubMed Web of Science ®Google Scholar
• Peinado H , AlečkovićM, LavotshkinSet al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastaticphenotype through MET. Nat. Med.18(6), 883–891 (2012).
   PubMed Web of Science ®Google Scholar
• Valadi H , EkströmK, BossiosAet al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol.9(6), 654–659 (2007).
   PubMed Web of Science ®Google Scholar
• Baumgart S , HöltersS, OhlmannCHet al. Exosomes of invasive urothelial carcinoma cells are characterized by a specific miRNA expression signature. Oncotarget8(35), 58278–58291 (2017).
   PubMedGoogle Scholar
• Salehi M , SharifiM. Exosomal miRNAs as novel cancer biomarkers: challenges and opportunities. J. Cell. Physiol.233(9), 6370–6380 (2018).
   PubMed Web of Science ®Google Scholar
• Liao J , LiuR, YinL, PuY. Expression profiling of exosomal miRNAs derived from human esophageal cancer cells by Solexa high-throughput sequencing. Int. J. Mol. Sci.15(9), 15530–15551 (2014).
   PubMed Web of Science ®Google Scholar
• Liao J , LiuR, ShiYJ, YinLH, PuYP. Exosome-shuttling microRNA-21 promotes cell migration and invasion-targeting PDCD4 in esophageal cancer. Int. J. Oncol.48(6), 2567–2579 (2016).
   PubMed Web of Science ®Google Scholar
• Li Z , MaYY, WangJet al. Exosomal microRNA-141 is upregulated in the serum of prostate cancer patients. Onco Targets Ther.9, 139–148 (2015).
   PubMed Web of Science ®Google Scholar
• Gheinani AH , VögeliM, BaumgartnerUet al. Improved isolation strategies to increase the yield and purity of human urinary exosomes for biomarker discovery. Sci. Rep.8(1), 3945 (2018).
   PubMedGoogle Scholar
• Fuessel S , Lohse-FischerA, Vu VanD, SalomoK, ErdmannK, WirthMP. Quantification of microRNAs in urine-derived specimens. Methods Mol. Biol.1655, 201–226 (2018).
   PubMedGoogle Scholar
• Wani S , KaulD, MavuduruRS, KakkarN, BhatiaA. Urinary-exosomal miR-2909: a novel pathognomonic trait of prostate cancer severity. J. Biotechnol.259, 135–139 (2017).
   PubMed Web of Science ®Google Scholar
• Di Meo A , BartlettJ, ChengY, PasicMD, YousefGM. Liquid biopsy: a step forward towards precision medicine in urologic malignancies. Mol. Cancer16(1), 80 (2017).
   PubMedGoogle Scholar
• Royo F , DiwanI, TackettMRet al. Comparative miRNA analysis of urine extracellular vesicles isolated through five different methods. Cancers (Basel)8(12), 112 (2016).
   PubMed Web of Science ®Google Scholar
• Long JD , SullivanTB, HumphreyJet al. A non-invasive miRNA based assay to detect bladder cancer in cell-free urine. Am. J. Transl. Res.7(11), 2500–2509 (2015).
   PubMed Web of Science ®Google Scholar
• Armstrong DA , GreenBB, SeigneJD, SchnedAR, MarsitCJ. MicroRNA molecular profiling from matched tumor and bio-fluids in bladder cancer. Mol. Cancer14, 194 (2015).
   PubMed Web of Science ®Google Scholar
• Cheng L , SunX, SciclunaBJ, ColemanBM, HillAF. Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in humanurine. Kidney Int.86(2), 433–444 (2014).
   PubMed Web of Science ®Google Scholar
• Lin XQ , HuangB. Research progress of exosomes applied in tumor liquid biopsy. Exp. Lab. Med.34(5), 535–538 (2016).
   Google Scholar
• Kalluri R , LeBleuVS. Discovery of double-stranded genomic DNA in circulating exosomes. Cold Spring Harb. Symp. Quant. Biol.81, 275–280 (2016).
   PubMedGoogle Scholar
• Thakur BK , ZhangH, BeckerAet al. Double-stranded DNA in exosomes: a novel biomarker in cancer detection. Cell. Res.24(6), 766–769 (2014).
   PubMed Web of Science ®Google Scholar
• Yang S , CheSP, KurywchakPet al. Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer. Cancer Biol. Ther.18(3), 158–165 (2017).
   PubMed Web of Science ®Google Scholar
• Castillo J , BernardV, SanLucas FAet al. Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients. Ann. Oncol.29(1), 223–229 (2018).
   PubMed Web of Science ®Google Scholar
• Record M , CarayonK, PoirotM, Silvente-PoirotS. Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies. Biochim. Biophys. Acta.1841(1), 108–120 (2014).
   PubMed Web of Science ®Google Scholar
• Colombo M , RaposoG, TheryC. Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu. Rev. Cell. Dev. Biol.30, 255–289 (2014).
   PubMed Web of Science ®Google Scholar
• Li Y , ZhengQ, BaoCet al. Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis. Cell. Res.25(8), 981–984 (2015).
   PubMed Web of Science ®Google Scholar
• Ge Q , ZhouY, LuJ, BaiY, XieX, LuZ. miRNA in plasma exosome is stable under different storage conditions. Molecules19(2), 1568–1575 (2014).
   PubMed Web of Science ®Google Scholar
• Urbanelli L , BurattaS, SaginiK, FerraraG, LanniM, EmilianiC. Exosome-based strategies for diagnosis and therapy. Recent Pat. CNS Drug Discov.10(1), 10–27 (2015).
   PubMedGoogle Scholar
• Dang VD , JellaKK, RaghebRRT, DenslowND, AlliAA. Lipidomic and proteomic analysis of exosomes from mouse cortical collecting duct cells. FASEB J.31(12), 5399–5408 (2017).
   PubMed Web of Science ®Google Scholar
• Zhang M , ZhangCG, DingW. Exosome in cancer diagnosis and treatment. Prog. Physiol. Sci.45(5), 372–377 (2014).
   PubMedGoogle Scholar
• Kalluri R . The biology and function of exosomes in cancer. J. Clin. Invest.126(4), 1208–1215 (2016).
   PubMed Web of Science ®Google Scholar
• Melo SA , LueckeLB, KahlertCet al. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature523(7559), 177–182 (2015).
   PubMed Web of Science ®Google Scholar
• Melo SA . Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. Cancer Cell.26(5), 707–721 (2014).
   PubMed Web of Science ®Google Scholar
• Caradec J , KharmateG, Hosseini-BeheshtiE, AdomatH, GleaveM, GunsE. Reproducibility and efficiency of serum-derived exosome extraction methods. Clin. Biochem.47(13–14), 1286–1292 (2014).
   PubMed Web of Science ®Google Scholar
• Zhao L , YuJ, WangJ, LiHH, CheJJ, CaoBW. Isolation and identification of miRNAs in exosomes derived from serum of colon cancer patients. J. Cancer8(7), 1145–1152 (2017).
   PubMed Web of Science ®Google Scholar
• Greening DW , XuR, JiH, TauroBJ, SimpsonRJ. A protocol for exosome isolation and characterization: evaluation of ultracentrifugation, density-gradient separation, and immunoaffinity capture methods. Methods Mol. Biol.1295, 179–209 (2015).
   PubMedGoogle Scholar
• Xu XD , LiuZH. Biological function and isolation methods of exosomes. J. Nephrol. Dialy. Transplant.26(2), 159–163 (2017).
   Google Scholar
• Zarovni N , CorradoA, GuazziPet al. Integrated isolation and quantitative analysis of exosome shuttled proteins and nucleic acids using immunocapture approaches. Methods87, 46–58 (2015).
   PubMed Web of Science ®Google Scholar
• Kim J , TanZ, LubmanDM. Exosome enrichment of human serum using multiple cycles of centrifugation. Electrophoresis36(17), 2017–2026 (2015).
   PubMed Web of Science ®Google Scholar
• Smith RA , LamAK. Liquid biopsy for investigation of cancer DNA in esophageal adenocarcinoma: cell-free plasma DNA and exosome-associated DNA. Methods Mol. Biol.1756, 187–194 (2018).
   PubMedGoogle Scholar
• Liao J . Study on the mechanism of exosome-shuttling microRNAs in human esophageal cancer microenvironment [PhD Thesis]. Southeast University, Nanjing, China (2016).
   Google Scholar
• Wang QL , ZhuangX, SriwastvaMKet al. Blood exosomes regulate the tissue distribution of grapefruit-derived nanovector via CD36 and IGFR1 pathways. Theranostics8(18), 4912–4924 (2018).
   PubMed Web of Science ®Google Scholar
• Shi YJ . Study on the association between exosomes shuttling miR-21 and Incidence of esophageal cancer [PhD Thesis]. Southeast University, Nanjing, China (2014).
   Google Scholar
• Lin F , WangHJ, LiCXet al. Effects of esophageal cancer cell-derived exosomes on cancer cell migration and invasion and its mechanism research. Med. J. Chin. PLA42(4), 307–313 (2017).
   Google Scholar
• Khazaei S , NouraeeN, MoradiA, MowlaSJ. A novel signaling role for miR-451 in esophageal tumor microenvironment and its contribution to tumor progression. Clin. Transl. Oncol.19(5), 633–640 (2017).
   PubMed Web of Science ®Google Scholar
• Tanaka Y , KamoharaH, KinoshitaKet al. Clinical impact of serum exosomal microRNA-21 as a clinical biomarker in human esophageal squamous cell carcinoma. Cancer119(6), 1159–1167 (2013).
   PubMed Web of Science ®Google Scholar
• Huang Z , ZhangL, ZhuDet al. A novel serum microRNA signature to screen esophageal squamous cell carcinoma. Cancer Med.6(1), 109–119 (2017).
   PubMed Web of Science ®Google Scholar
• Chiam K , WangT, WatsonDIet al. Circulating serum exosomal miRNAs as potential biomarkers for esophageal adenocarcinoma. J. Gastrointest. Surg.19(7), 1208–1215 (2015).
   PubMed Web of Science ®Google Scholar
• Warnecke-Eberz U , ChonSH, HölscherAH, DrebberU, BollschweilerE. Exosomal onco-miRs from serum of patients with adenocarcinoma of the esophagus: comparison of miRNA profiles of exosomes and matching tumor. Tumour Biol.36(6), 4643–4653 (2015).
   PubMedGoogle Scholar
• Nouraee N , KhazaeiS, VaseiM, RazavipourSF, SadeghizadehM, MowlaSJ. MicroRNAs contribution in tumor microenvironment of esophageal cancer. Cancer Biomark.16(3), 367–376 (2016).
   PubMed Web of Science ®Google Scholar
• Zhou X , WenW, ZhuJet al. A six-microRNA signature in plasma was identified as a potential biomarker in diagnosis of esophageal squamous cell carcinoma. Oncotarget8(21), 34468–34480 (2017).
   PubMedGoogle Scholar
• Katsuda T , KosakaN, OchiyaT. The roles of extracellular vesicles in cancer biology: toward the development of novel cancer biomarkers. Proteomics14, 412–425 (2014).
   PubMed Web of Science ®Google Scholar
• Shao H , ChungJ, IssadoreD. Diagnostic technologies for circulating tumour cells and exosomes. Biosci. Rep.36(1), e00292 (2015).
   PubMedGoogle Scholar
• Zhang W , XiaW, LvZ, NiC, XinY, YangL. Liquid biopsy for cancer: circulating tumor cells, circulating free DNA or exosomes?Cell. Physiol. Biochem.41(2), 755–768 (2017).
   PubMedGoogle Scholar
• He M , ZengY. Microfluidic exosome analysis toward liquid biopsy for cancer. J. Lab. Autom.21(4), 599–608 (2016).
   PubMedGoogle Scholar
• Ekström EJ , BergenfelzC, von BülowVet al. WNT5A induces release of exosomes containing pro-angiogenic and immunosuppressive factors from malignant melanoma cells. Mol. Cancer.13, 88 (2014).
   PubMed Web of Science ®Google Scholar
• Min H , SunX, YangXet al. Exosomes derived from irradiated esophageal carcinoma-infiltrating T cells promote metastasis by inducing the epithelial-mesenchymal transition in esophageal cancer cells. Pathol. Oncol. Res.24(1), 11–18 (2018).
   PubMed Web of Science ®Google Scholar