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Biomarkers in Medicine Volume 13, 2019 - Issue 14
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Research Article

The Relationship Between CYP7A1 Polymorphisms, Coronary Artery Disease & Serum Lipid Markers

Tomasz Iwanicki1 Department of Biochemistry & Medical Genetics, School of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, PolandCorrespondence[email protected]
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,
Anna Balcerzyk1 Department of Biochemistry & Medical Genetics, School of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, PolandView further author information
,
Paweł Niemiec1 Department of Biochemistry & Medical Genetics, School of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, PolandView further author information
,
Wanda Trautsolt2 Department of Internal Medicine, Diabetes & Nephrology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, 3 Maja Street 13–18, 41-800 Zabrze, PolandView further author information
,
Władysław Grzeszczak2 Department of Internal Medicine, Diabetes & Nephrology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, 3 Maja Street 13–18, 41-800 Zabrze, PolandView further author information
,
Anna Ochalska-Tyka3 Regional Centre of Blood Donation & Blood Treatment in Raciborz, Sienkiewicza Street 3, 47-400 Raciborz, PolandView further author information
,
Jolanta Krauze4 1st Department of Cardiac Surgery in Upper Silesian Center of Cardiology in Katowice, School of Medicine in Katowice, Medical University of Silesia, Ziolowa Street 47, 40-635 Katowice, PolandView further author information
,
Tomasz Nowak1 Department of Biochemistry & Medical Genetics, School of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, PolandView further author information
&
Iwona Żak1 Department of Biochemistry & Medical Genetics, School of Health Sciences in Katowice, Medical University of Silesia, Medykow Street 18, 40-752 Katowice, PolandView further author information
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Pages 1199-1208 | Received 07 Dec 2018, Accepted 16 Jul 2019, Published online: 03 Oct 2019

References

  • Pikuleva IA . Cholesterol-metabolizing cytochromes P450. Drug Metab. Dispos.34(4), 513–520 (2006).
  • Björkhem I , ArayaZ, RudlingM, AngelinB, EinarssonC, WikvallK. Differences in the regulation of the classical and the alternative pathway for bile acid synthesis in human liver. No coordinate regulation of CYP7A1 and CYP27A1. J. Biol. Chem.277(30), 26804–26807 (2002).
  • Pullinger CR , EngC, SalenGet al. Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype. J. Clin. Invest.110(1), 109–117 (2002).
  • Wang J , FreemanDJ, GrundySM, LevineDM, GuerraR, CohenJC. Linkage between cholesterol 7α-hydroxylase and high plasma low-density lipoprotein cholesterol concentrations. J. Clin. Invest.101, 1283–1291 (1998).
  • Couture P , OtvosJD, CupplesLA, WilsonPWF, SchaeferEJ, OrdovasJM. Association of the A-204C polymorphism in the cholesterol 7(α)- hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study. J. Lipid Res.40(10), 1883–1889 (1999)
  • Qayyum F , LauridsenB, Frikke-SchmidtR, NordestgaardB, Tybjærg-HansenA. Genetic variants in CYP7A1 and risk of myocardial infarction and symptomatic gallstone disease. Atherosclerosis39(22), 2106–2116 (2017).
  • Hofman MK , PrincenHM, ZwindermanAH, WouterJukema J. Genetic variation in the rate-limiting enzyme in cholesterol catabolism (cholesterol 7α-hydroxylase) influences the progression of atherosclerosis and risk of new clinical events. Clin. Sci.108(6), 539–545 (2005).
  • Iwanicki T , BalcerzykA, NiemiecPet al. CYP7A1 gene polymorphism located in the 5′ upstream region modifies the risk of coronary artery disease. Dis. Markers.2015, 185969 (2015).
  • Wang D , HartmannK, SewerynM, SadeeW. Interactions between regulatory variants in CYP7A1 (cholesterol 7α-hydroxylase) promoter and enhancer regions regulate CYP7A1 expression. Circ. Genomic Precis. Med. (10), e002082 (2018).
  • Fu L , ZhaoY, WuXet al. CYP7A1 genotypes and haplotypes associated with hypertension in an obese Han Chinese population. Hypertens. Res.34(6), 722–727 (2011).
  • Wertheim BC , SmithJW, FangC, AlbertsDS, LanceP, ThompsonPA. Risk modification of colorectal adenoma by CYP7A1 polymorphisms and the role of bile acid metabolism in carcinogenesis. Cancer Prev. Res.5(2), 197–204 (2012).
  • Ito H , MatsuoK, HosonoSet al. Association between CYP7A1 and the risk of proximal colon cancer in Japanese. Int. J. Mol. Epidemiol. Genet.1(1), 35–46 (2010).
  • Friedewald WT , LevyRI, FredricksonDS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem.18(6), 499–502 (1972).
  • Morcillo-Suarez C , AlegreJ, SangrosRet al. SNP analysis to results (SNPator): a web-based environment oriented to statistical genomics analyses upon SNP data. Bioinformatics24(14), 1643–1644 (2008).
  • Purcell S , NealeB, Todd-BrownKet al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet.81(3), 559–575 (2007).
  • Horita N , KanekoT. Genetic model selection for a case–control study and a meta-analysis. Meta Gene5, 1–8 (2015).
  • Barrett JC , FryB, MallerJ, DalyMJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics21(2), 263–265 (2005).
  • Gabriel SB , SchaffnerSF, NguyenHet al. The structure of haplotype blocks in the human genome. Science296(5576), 2225–2229 (2002).
  • Lambrinoudaki IV , KaparosGI, VlachouS aet al. CYP A-204C polymorphism is associated with subclinical atherosclerosis in postmenopausal women. Menopause15(6), 1163–1168 (2008).
  • Iorga A , CunninghamCM, MoazeniS, RuffenachG, UmarS, EghbaliM. The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy. Biol. Sex Differ.8(1), 33 (2017).
  • Miyake JH , WangSL, DavisRA. Bile acid induction of cytokine expression by macrophages correlates with repression of hepatic cholesterol 7alpha-hydroxylase. J. Biol. Chem.275(29), 21805–21808 (2000).
  • Cai Q , WangZQ, CaiQ, LiC, ChenEZ, JiangZY. Relationship between CYP7A1-204A>C polymorphism with gallbladder stone disease and serum lipid levels: a meta-analysis. Lipids Health Dis.13(1), 126 (2014).
  • Klein C , LohmannK, ZieglerA. The promise and limitations of genome-wide association studies. J. Am. Med. Assoc.308(18), 1867–1868 (2012).

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