Prognostic Value of D-Dimer/Fibrinogen Ratio in the Adverse Outcomes of Patients Hospitalized for Heart Failure

References

• Taylor CJ , Ordóñez-MenaJM, RoalfeAKet al. Trends in survival after a diagnosis of heart failure in the United Kingdom 2000-2017: population based cohort study. BMJ (Clin. Res. Ed.).364, l223 (2019).
   PubMedGoogle Scholar
• Greene SJ , FonarowGC, VaduganathanMet al. The vulnerable phase after hospitalization for heart failure. Nat. Rev. Cardiol.12(4), 220–229 (2015).
   PubMed Web of Science ®Google Scholar
• Farmakis D , FilippatosG, LainscakMet al. Anticoagulants, antiplatelets and statins in heart failure. Cardiol. Clin.26(1), 49–58 (2008).
   PubMed Web of Science ®Google Scholar
• Uretsky BF , ThygesenK, ArmstrongPWet al. Acute coronary findings at autopsy in heart failure patients with sudden death: results from the assessment of treatment with lisinopril and survival (ATLAS) trial. Circulation102(6), 611–616 (2000).
   PubMed Web of Science ®Google Scholar
• Issa VS , DinardiLF, PereiraTVet al. Diagnostic discrepancies in clinical practice: an autopsy study in patients with heart failure. Medicine96(4), e5978 (2017).
   PubMed Web of Science ®Google Scholar
• Lip GY , GibbsCR. Does heart failure confer a hypercoagulable state? Virchow's triad revisited. J. Am. Coll. Cardiol.33(5), 1424–1426 (1999).
   PubMed Web of Science ®Google Scholar
• Anderson RA , EllisGR, ChirkovYYet al. Determinants of platelet responsiveness to nitric oxide in patients with chronic heart failure. Eur. J. Heart Fail.6(1), 47–54 (2004).
   PubMed Web of Science ®Google Scholar
• Weitz JI , FredenburghJC, EikelboomJW. A test in context: D-Dimer. J. Am. Coll. Cardiol.70(19), 2411–2420 (2017).
   PubMed Web of Science ®Google Scholar
• Arbustini E , NarulaN, D'ArminiAM. Fibrinogen: a circulating factor in search of its genetic architecture. Circulation128(12), 1276–1280 (2013).
   PubMed Web of Science ®Google Scholar
• Wuillemin WA , KorteW, WaserG, LämmleB. Usefulness of the D-dimer/fibrinogen ratio to predict deep venous thrombosis. J. Thromb. Haemost.3(2), 385–387 (2005).
   PubMed Web of Science ®Google Scholar
• Hajsadeghi S , KermanSR, KhojandiMet al. Accuracy of D-dimer:fibrinogen ratio to diagnose pulmonary thromboembolism in patients admitted to intensive care units. Cardiovasc. J. Afr.23(8), 446–456 (2012).
   PubMed Web of Science ®Google Scholar
• Kucher N , KohlerHP, DornhöferT, WallmannD, LämmleB. Accuracy of D-dimer/fibrinogen ratio to predict pulmonary embolism: a prospective diagnostic study. J. Thromb. Haemost.1(4), 708–713 (2003).
   PubMed Web of Science ®Google Scholar
• Alvarez-Perez FJ , Castelo-BrancoM, Alvarez-SabinJ. Usefulness of measurement of fibrinogen, D-dimer, D-dimer/fibrinogen ratio, C reactive protein and erythrocyte sedimentation rate to assess the pathophysiology and mechanism of ischemic stroke. J. Neurol. Neurosurg. Psychiatry82(9), 986–992 (2011).
   PubMed Web of Science ®Google Scholar
• Cai HX , LiXQ, WangSF. Prognostic value of fibrinogen and D-dimer-fibrinogen ratio in resectable gastrointestinal stromal tumors. World J. Gastroentero.24(44), 5046–5056 (2018).
   PubMed Web of Science ®Google Scholar
• Bai Y , ShiM, YangXet al. The value of FDP/FIB and D-dimer/FIB ratios in predicting high-risk APL-related thrombosis. Leukemia res.79, 34–37 (2019).
   PubMed Web of Science ®Google Scholar
• Xu DX , DuWT, LiX, WuZX, YuGF. D-dimer/fibrinogen ratio for the prediction of progressive hemorrhagic injury after traumatic brain injury. Clin. Chim. Acta.507, 143–148 (2020).
   PubMed Web of Science ®Google Scholar
• Mongirdiene A , KursvietieneL, KasauskasA. The coagulation system changes in patients with chronic heart failure. Medicina (Kaunas, Lithuania).46(9), 642–647 (2010).
   PubMed Web of Science ®Google Scholar
• Sbarouni E , BradshawA, AndreottiFet al. Relationship between hemostatic abnormalities and neuroendocrine activity in heart failure. Am. Heart J.127(3), 607–612 (1994).
   PubMed Web of Science ®Google Scholar
• Hamatani Y , NagaiT, NakaiMet al. Elevated plasma D-Dimer level is associated with short-term risk of ischemic stroke in patients with acute heart failure. Stroke49(7), 1737–1740 (2018).
   PubMed Web of Science ®Google Scholar
• Minami Y , HarukiS, JujoKet al. Elevated D-dimer levels predict an adverse outcome in hospitalized patients with acute decompensated heart failure. Int. J. Cardiol.204, 42–44 (2016).
   PubMed Web of Science ®Google Scholar
• Huang B , LiYJ, ShenJet al. D-dimer level and long-term outcome in patients with end-stage heart failure secondary to idiopathic dilated cardiomyopathy. J. Geriatr. Cardiol.16(8), 621–629 (2019).
   PubMedGoogle Scholar
• Yucel O , YucelH, ZorluA. D-dimer is a predictor of cardiovascular death, and new-onset atrial fibrillation in patients with systolic heart failure. Int. J. Cardiol.247, 39 (2017).
   PubMed Web of Science ®Google Scholar
• Yan W , LiuJ, LiuHet al. Elevated D-dimer levels predict adverse outcomes in hospitalised elderly patients with chronic heart failure. Intern. Med. J.49(10), 1299–1306 (2019).
   PubMed Web of Science ®Google Scholar
• Zorlu A , YilmazMB, YucelHet al. Increased d-dimer levels predict cardiovascular mortality in patients with systolic heart failure. J. Thromb. Thrombolys33(4), 322–328 (2012).
   PubMed Web of Science ®Google Scholar
• [Chinese guidelines for the diagnosis and treatment of heart failure 2018]. Zhonghua Xin Xue Guan Bing Za Zhi.46(10), 760–789 (2018).
   PubMedGoogle Scholar
• Sajeev CG , RajanNS, GeorgeB, RajeshGN, KrishnanMN. Demographical and clinicopathological characteristics in heart failure and outcome predictors: a prospective, observational study. ESC Heart Fail.4(1), 16–22 (2017).
   PubMed Web of Science ®Google Scholar
• Ostręga M , GierlotkaMJ, SłonkaG, NadziakiewiczP, GąsiorM. Clinical characteristics, treatment, and prognosis of patients with ischemic and nonischemic acute severe heart failure. Analysis of data from the COMMIT-AHF registry. Pol. Arch. Intern. Med.127(5), 328–335 (2017).
   PubMedGoogle Scholar
• Angaran P , DorianP, HaACTet al. Association of left ventricular ejection fraction with mortality and hospitalizations. Journal of the American Society of Echocardiography (2020).
   Web of Science ®Google Scholar
• Di Tullio MR , QianM, ThompsonJLet al. Left ventricular ejection fraction and risk of stroke and cardiac events in heart failure: data from the warfarin versus aspirin in reduced ejection fraction trial. Stroke47(8), 2031–2037 (2016).
   PubMed Web of Science ®Google Scholar
• Lerman BJ , PopatRA, AssimesTL, HeidenreichPA, WrenSM. Association of left ventricular ejection fraction and symptoms with mortality after elective noncardiac surgery among patients with heart failure. JAMA321(6), 572–579 (2019).
   PubMed Web of Science ®Google Scholar
• Gotsman I , ShauerA, ZwasDRet al. Low serum albumin: A significant predictor of reduced survival in patients with chronic heart failure. Clin. Cardiol.42(3), 365–372 (2019).
   PubMed Web of Science ®Google Scholar
• Takaya Y , YoshiharaF, YokoyamaHet al. Impact of decreased serum albumin levels on acute kidney injury in patients with acute decompensated heart failure: a potential association of atrial natriuretic peptide. Heart Vessels32(8), 932–943 (2017).
   PubMed Web of Science ®Google Scholar
• Li K , FuW, BoY, ZhuY. Effect of albumin-globulin score and albumin to globulin ratio on survival in patients with heart failure: a retrospective cohort study in China. BMJ Open8(7), e22960 (2018).
   Web of Science ®Google Scholar
• Prenner SB , PillutlaR, YenigallaSet al. Serum Albumin Is a Marker of Myocardial Fibrosis, Adverse Pulsatile Aortic Hemodynamics, and Prognosis in Heart Failure With Preserved Ejection Fraction. J Am. Heart Assoc.9(3), e14716 (2020).
   Web of Science ®Google Scholar
• Weng TP , FuTC, WangCH, HsuCC, WangJS. Activation of lymphocyte autophagy/apoptosis reflects haemodynamic inefficiency and functional aerobic impairment in patients with heart failure. Clin. Sci.127(10), 589–602 (2014).
   Web of Science ®Google Scholar
• Carubelli V , BonadeiI, CastriniAIet al. Prognostic value of the absolute lymphocyte count in patients admitted for acute heart failure. J. Cardiovasc. Med.18(11), 859–865 (2017).
   Google Scholar
• Vaduganathan M , AmbrosyAP, GreeneSJet al. Predictive value of low relative lymphocyte count in patients hospitalized for heart failure with reduced ejection fraction: insights from the EVEREST trial. Circ. Heart Fail.5(6), 750–758 (2012).
   PubMed Web of Science ®Google Scholar
• Acanfora D , GheorghiadeM, TrojanoLet al. Relative lymphocyte count: a prognostic indicator of mortality in elderly patients with congestive heart failure. Am. Heart J.142(1), 167–173 (2001).
   PubMed Web of Science ®Google Scholar
• Mele D , NardozzaM, FerrariR. Left ventricular ejection fraction and heart failure: an indissoluble marriage?Eur. J. Heart Fail.20(3), 427–430 (2018).
   PubMed Web of Science ®Google Scholar
• Bui AL , Grau-SepulvedaMV, HernandezAFet al. Admission heart rate and in-hospital outcomes in patients hospitalized for heart failure in sinus rhythm and in atrial fibrillation. Am. Heart J.165(4), 567–574 (2013).
   PubMed Web of Science ®Google Scholar
• Greene SJ , VaduganathanM, WilcoxJEet al. The prognostic significance of heart rate in patients hospitalized for heart failure with reduced ejection fraction in sinus rhythm: insights from the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study With Tolvaptan) trial. JACC Heart Fail.1(6), 488–496 (2013).
   PubMed Web of Science ®Google Scholar
• Hiki M , IwataH, TakasuKet al. Elevated heart rate in combination with elevated blood pressure predicts lower cardiovascular mortality in acute decompensated heart failure. Int. Heart J.61(2), 308–315 (2020).
   PubMed Web of Science ®Google Scholar
• Erez O , MastroliaSA, ThachilJ. Disseminated intravascular coagulation in pregnancy: insights in pathophysiology, diagnosis and management. Am. J. Obstet. Gynecol.213(4), 452–463 (2015).
   PubMed Web of Science ®Google Scholar
• Kerr R , StirlingD, LudlamCA. Interleukin 6 and haemostasis. Br. J. Haematol.115(1), 3–12 (2001).
   PubMed Web of Science ®Google Scholar
• Markousis-Mavrogenis G , TrompJ, OuwerkerkWet al. The clinical significance of interleukin-6 in heart failure: results from the BIOSTAT-CHF study. Eur. J. Heart Fail.21(8), 965–973 (2019).
   PubMed Web of Science ®Google Scholar
• Levi M , TohCH, ThachilJ, WatsonHG. Guidelines for the diagnosis and management of disseminated intravascular coagulation. Brit. J. Haematol.145(1), 24–33 (2009).
   PubMed Web of Science ®Google Scholar
• Sarcon A , LiuX, TonD, HaywoodJ, HitchcockT. Advanced congestive heart failure associated with disseminated intravascular coagulopathy. J. Investig. Med. High Impact Case Rep.3(4), 1562878846 (2015).
   Google Scholar
• Belov D , LyubarovaR, FeinS, TorosoffM. Disseminated intravascular coagulation with congestive heart failure and left ventricular thrombus: a case report with literature review of 7 cases. Am. J. Case Rep.16(53–56) (2015).
   PubMedGoogle Scholar
• Itani R , MinamiY, HarukiS, WatanabeE, HagiwaraN. Prognostic impact of disseminated intravascular coagulation score in acute heart failure patients referred to a cardiac intensive care unit: a retrospective cohort study. Heart Vessels.32(7), 872–879 (2017).
   PubMed Web of Science ®Google Scholar
• Chin BS , BlannAD, GibbsCRet al. Prognostic value of interleukin-6, plasma viscosity, fibrinogen, von Willebrand factor, tissue factor and vascular endothelial growth factor levels in congestive heart failure. Eur. J. Clin. Invest.33(11), 941–948 (2003).
   PubMed Web of Science ®Google Scholar
• Okada A , SuganoY, NagaiTet al. Prognostic value of prothrombin time international normalized ratio in acute decompensated heart failure-a combined marker of hepatic insufficiency and hemostatic abnormality. Circ. J.80(4), 913–923 (2016).
   PubMed Web of Science ®Google Scholar
• Alehagen U , DahlströmU, LindahlTL. Low plasma concentrations of coagulation factors II, VII and XI indicate increased risk among elderly with symptoms of heart failure. Blood Coagul. Fibrinolysis21(1), 62–69 (2010).
   PubMed Web of Science ®Google Scholar
• Ponikowski P , VoorsAA, AnkerSDet al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur. Heart J.37(27), 2129–2200 (2016).
   PubMed Web of Science ®Google Scholar
• Zannad F , AnkerSD, ByraWMet al. Rivaroxaban in patients with heart failure, sinus rhythm, and coronary disease. N. Engl. J. Med.379(14), 1332–1342 (2018).
   PubMed Web of Science ®Google Scholar
• Cleland JG , FindlayI, JafriSet al. The Warfarin/Aspirin Study in Heart failure (WASH): a randomized trial comparing antithrombotic strategies for patients with heart failure. Am. Heart J.148(1), 157–164 (2004).
   PubMed Web of Science ®Google Scholar
• Cokkinos DV , HaralabopoulosGC, KostisJB, ToutouzasPK. Efficacy of antithrombotic therapy in chronic heart failure: the HELAS study. Eur. J. Heart Fail.8(4), 428–432 (2006).
   PubMed Web of Science ®Google Scholar
• Massie BM , CollinsJF, AmmonSEet al. Randomized trial of warfarin, aspirin, and clopidogrel in patients with chronic heart failure: the Warfarin and Antiplatelet Therapy in Chronic Heart Failure (WATCH) trial. Circulation119(12), 1616–1624 (2009).
   PubMed Web of Science ®Google Scholar
• Homma S , ThompsonJL, PullicinoPMet al. Warfarin and aspirin in patients with heart failure and sinus rhythm. N. Engl. J. Med.366(20), 1859–1869 (2012).
   PubMed Web of Science ®Google Scholar
• Filippatos G , FarmakisD. A look back: the quest for thrombosis in heart failure continues after COMMANDER HF. Cardiovasc. Res.115(13), e140–e142 (2019).
   PubMed Web of Science ®Google Scholar
• Ferreira JP , LamCSP, AnkerSDet al. Plasma D-dimer concentrations predicting stroke risk and rivaroxaban benefit in patients with heart failure and sinus rhythm: an analysis from the COMMANDER-HF trial. Eur. J. Heart Fail. doi:10.1002/ejhf.2003 (2020).
   Web of Science ®Google Scholar