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Review

Smoking and Atherosclerotic Cardiovascular Disease: Part I: Atherosclerotic Disease Process

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Pages 411-428 | Published online: 06 Aug 2009

Bibliography

  • Kannel W : Contributions of the Framingham study to the conquest of coronary artery disease.Am. J. Cardiol.62, 1109–1112 (1988).
  • Bradford Hill A : The environment and disease: association or causation.Proc. R. Soc. Med.58, 295–300 (1965).
  • Greenlee RT , Hill-HarmonMB, MurrayT, ThunM: Cancer statistics, 2001.CA Cancer J. Clin.51, 15–36 (2001).
  • Willett WC , GreenA, StampferMJet al.: Relative and absolute excess risks of coronary heart disease among women who smoke cigarettes.N. Engl. J. Med.317, 1303–1309 (1987).
  • McGinnis JM , FoegeWH: Actual causes of death in the united states.J. Am. Med. Assoc.270, 2207–2212 (1993).
  • Nilsson S , CarstensenJM, PershagenG: Mortality among male and female smokers in sweden: a 33 year follow up.J. Epidemiol. Commun. Health55, 825–830 (2001).
  • Center for Disease Control and Prevention: Annual smoking-attributable mortality, years of potential life lost, and economic costs – United States, 1995–1999. MMWR Morb. Mortal. Wkly Rep.51, 300–303 (2002).
  • Ezzati M , HenleySJ, ThunMJ, LopezAD: Role of smoking in global and regional cardiovascular mortality.Circulation112, 489–497 (2005).
  • Bronnum-Hansen H : Predicted effect of smoking cessation of tobacco-related mortality.Ugeskr. Laeg.162, 5772–5777 (2000).
  • Feenstra TL , van GenugtenML, HoogenveenRT, WoutersEF, Rutten-van MolkenMP: The impact of aging and smoking on the future burden of chronic obstructive pulmonary disease: a model analysis in The Netherlands. Am. J. Respir. Crit. Care Med.164, 590–596 (2001).
  • Jones A : Causes and effects of chronic obstructive pulmonary disease.Br. J. Nurs.10, 845–850 (2001).
  • Lundback B , LindbergA, LindstromMet al.: Not 15 but 50% of smokers develop COPD? – Report from the obstructive lung disease in northern Sweden studies.Respir. Med.97, 115–122 (2003).
  • Siafakas NM , TzortzakiEG: Few smokers develop COPD. Why.Respir. Med.96, 615–624 (2002).
  • Hyland A , VenaC, BauerJet al.: Cigarette smoking-attributable mobidity united states 2000.Morb. Mortal. Wkly Rep.52, 842–844 (2003).
  • Ando M , WakaiK, SekiNet al.: Attributable and absolute risk of lung cancer death by smoking status: findings from the Japan collaborative cohort study.Int. J. Cancer105, 249–254 (2003).
  • Darby SC , DollR, StrattonIM: Trends in mortality from smoking-related diseases in England and Wales. In: Nicotine, Smoking, and the Low Tar Programme. Wald N, Froggatt P (Eds). Oxford University Press, Oxford, UK (1989).
  • Institute of Medicine: Clearing the smoke: assessing the science base for tobacco harm reduction. Executive summary, research conclusions and recommendations. Institute of Medicine, Washington, DC, USA (2001).
  • Ebert RV : Cessation of cigarette smoking and pulmonary disease.J. Am. Med. Assoc.240, 2159–2161 (1978).
  • Doll R , PetoR, WheatleyK, GrayR, SutherlandI: Mortality in relation to smoking: 40 years‘ observations on male british doctors.Br. Med. J.309, 901–911 (1994).
  • Wu MS , WuCY, ChenCJ, LinMT, ShunCT, LinJT: Interleukin-10 genotypes associate with the risk of gastric carcinoma in Taiwanese Chinese.Int. J. Cancer104, 617–623 (2003).
  • Kato I , NomuraA, StemmermannG, ChyouP: A prospective study of gastric and duodenal ulcer and its relation to smoking, alcohol, and diet.Am. J. Epidemiol.135, 521–530 (1992).
  • Department of Health, Education and Welfare: Smoking and health: a report of the US Surgeon General. US DHEW, Washington, DC, USA publication no. (PHS) 79–50066 (1979).
  • Rhodes J , GAT: Smoking: good or bad for inflammatory bowel disease.Gastroenterology106, 807–810 (1994).
  • Calkins BM : A meta-analysis of the role of smoking in inflammatory bowel disease.Dig. Dis. Sci.34, 1841–1854 (1989).
  • Duffy LC , ZieleznyMA, MarshallJRet al.: Cigarette smoking and risk of clinical relapse in patients with Crohn‘s disease.Am. J. Prev. Med.6, 161–166 (1990).
  • Cottone M , RosselliM, OrlandoAet al.: Smoking habits and recurrence in Crohn‘s disease.Gastroenterology106, 643–648 (1994).
  • Kurata JH , Kantor-FishS, FranklH, GodbyP, VadheimCM: Crohn‘s disease among ethnic groups in a large health maintenance organization.Gastroenterology102, 1940–1948 (1992).
  • Sutherland LR , RamcharanS, BryantH, FickG: Effect of cigarette smoking on recurrence of Crohn‘s disease.Gastroenterology98, 1123–1128 (1990).
  • Hujoel PP , DrangsholtM, SpiekermanC, DeRouenTA: Periodontitis-systemic disease associations in the presence of smoking – causal or coincidental.Periodontol. 200030, 51–60 (2002).
  • Haber J , WattlesJ, CrowleyM, MandellR, JoshipuraK, KentRL: Evidence for cigarette smoking as a major risk factor for periodontitis.J. Periodontol.64, 16–23 (1993).
  • Haber J , KentRL: Cigarette smoking in a periodontal practice.J. Periodontol.63, 100–106 (1992).
  • Bergstrom J : Tobacco smoking and supragingival dental calculus.J. Clin. Periodontol.26, 541–547 (1999).
  • Haber J : Smoking is a major risk factor for periodontitis.Curr. Opin. Periodontol.12–18 (1994).
  • Haber J : Cigarette smoking: a major risk factor for periodontitis.Compendium15, 1002, 1004–1008 (1994).
  • Hujoel PP : Does chronic periodontitis cause coronary heart disease? A review of the literature.J. Am. Dent. Assoc.133(Suppl.), 31S–36S (2002).
  • Horning GM , HatchCL, CohenME: Risk indicators for periodontitis in a military treatment population.J. Periodontol.63, 297–302 (1992).
  • Locker D , LeakeJ: Risk indicators and risk markers for periodontal disease experience in older adults living independently in Ontario, Canada.J. Dent. Res.72, 9–17 (1993).
  • Center for Disease Control and Prevention: Annual smoking-attributable morbidity United States, 2000. MMWR Morb. Mortal. Wkly Rep.52, 842–844 (2003).
  • Chen Z , BorehamJ: Smoking and cardiovascular disease.Semin. Vasc. Med.2, 243–252 (2002).
  • Ross R : Atherosclerosis – an inflammatory disease.N. Engl. J. Med.340, 115–126 (1999).
  • Szmitko PE , WangCH, WeiselRD, JeffriesGA, AndersonTJ, VermaS: Biomarkers of vascular disease linking inflammation to endothelial activation: part II.Circulation108, 2041–2048 (2003).
  • Szmitko P , WangC, WeiselR, de AmeidaJ, AndersonT, VermaS: New markers of inflammation and endothelial cell activation – part I. Circulation108, 1917–1923 (2003).
  • Badimon JJ , FusterV, ChesebroJH, BadimonL: Coronary atherosclerosis. A multifactorial disease.Circulation87(3 Suppl.), II3–I16 (1993).
  • Davignon J : The lipid hypothesis. Pathophysiological basis.Arch. Surg.113, 28–34 (1978).
  • Berliner J , NavabM, FogelmanAet al.: Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics.Circulation91, 2488–2496 (1995).
  • Lobstein JF : Traîte d‘Anatomie Pathologique (Volume 1). Imprimierie de FG Levrault, Imprimeur du Roi (Eds). Paris and Strasbourg, France (1829).
  • Keys A : Human atherosclerosis and diet.Circulation5, 115–118 (1952).
  • Virchow R : Über die parenchymatöse entzündung virchows.Arch. Path. Anat.4, 261–324 (1852).
  • Rokitansky C : Über eine der Wichtigsten Krankheiten der Arterien (Volume 4). Hof KK, Staatsdruckerei (Eds). Vienna, Austria, 1–72 (1852).
  • Anitschkow N : Über die atheroskerose der aorta beim kaninchen und über deren entstehungsbedingungen.Beitr. Pathol. Anat.59, 306–348 (1914).
  • Biermann L , RossR: Aging and atherosclerosis.Atheroscler. Rev.2, 79–85 (1977).
  • Aschoff L : Arteriosklerose.Medizinische Klinik (Beiheft 1) 10 (1914).
  • Hueck W : Über das mesenchym. Die bedeutung seiner entwicklung und seines baues fur die pathologie.Beitr. Pathol. Anat.66, 330–366 (1920).
  • Doerr W : Morphologische untersuchungen zur entstehung der aortensklerose.Dtsch. Med. Wochenschr.85, 1401–1405 (1960).
  • Dugiud J : Thrombosis as a factor of pathogenesis of coronary atherosclerosis.J. Pathol. Bacteriol.58, 207–211 (1948).
  • Hauss W , Junge-HülsingG: Veränderungen des bindegewebsstoffwechsels durch toxische, infektiöse und allergische einflüsse.Z. Rheumaforsch.20, 161–175 (1961).
  • Ross R , GlomsetJ: Atherosclerosis and the smooth muscle – proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis.Science80, 1332–1339 (1973).
  • Ross R , GlomsetJ, KariyaBet al.: A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro.Proc. Natl Acad. Sci. USA71, 1207–1211 (1976).
  • Ross MA , CrosleyLK, BrownKMet al.: Plasma concentrations of carotenoids and antioxidant vitamins in scottish males: influences of smoking.Eur. J. Clin. Nutr.49, 861–865 (1995).
  • Ross R : The pathogenesis of atherosclerosis: a perspective for the 1990s.Nature362, 801–809 (1993).
  • Ross R , GlomsetJ, HarkerL: Response to injury and atherogenesis.Am. J. Pathol.86, 675–684 (1977).
  • Munro J , CotranR: The pathogenesis of atherosclerosis: atherogenesis and inflammation.Lab. Invest.58, 249–261 (1988).
  • Bauriedel G , AndrieR, LikunguJAet al.: Persistenz von Chlamydia pneumonia in koronarem plaquegewebe. [Persistence of Chlamydia pneumoniae in coronary plaque tissue. A contribution to infection and immune hypothesis in unstable angina pectoris].Dtsch. Med. Wochenschr.124, 1408–1413 (1999).
  • Grayston JT , KuoCC, CoulsonASet al.: Chlamydia pneumoniae (twar) in atherosclerosis of the carotid artery [see comments].Circulation92, 3397–3400 (1995).
  • Jackson LA , CampbellLA, SchmidtRAet al.: Specificity of detection of Chlamydia pneumoniae in cardiovascular atheroma: Evaluation of the innocent bystander hypothesis.Am. J. Pathol.150, 1785–1790 (1997).
  • Jackson LA , CampbellLA, SchmidtRAet al.: Specificity of detection of Chlamydia pneumoniae in cardiovascular atheroma.J. Infect. Dis.181(Suppl. 3), S447–S448 (2000).
  • Kuo CC , GraystonJT, CampbellLA, GooYA, WisslerRW, BendittEP: Chlamydia pneumoniae (twar) in coronary arteries of young adults (15–34 years old).Proc. Natl Acad. Sci. USA92, 6911–6914 (1995).
  • Juvonen J , JuvonenT, LaurilaAet al.: Immunohistochemical detection of Chlamydia pneumoniae in abdominal aortic aneurysms.Ann. NY Acad. Sci.800, 236–238 (1996).
  • Maass M : Persistence of Chlamydia pneumoniae in human arteriosclerotic plaque substance. Evidence and consequences. [Persistenz von Chlamydiae pneumoniae in humanem artzeriosklerotischem plaquematerial].Herz23, 178–184 (1998).
  • Maass M , GieffersJ, SolbachW: Atherogenetically relevant cells support continuous growth of Chlamydia pneumoniae.Herz25, 68–72 (2000).
  • Melnick SL , ShaharE, FolsomARet al.: Past infection by Chlamydia pneumoniae strain twar and asymptomatic carotid atherosclerosis. Atherosclerosis Risk in Communities (ARIC) study investigators.Am. J. Med.95, 499–504 (1993).
  • Miettinen H , LehtoS, SaikkuPet al.: Association of Chlamydia pneumoniae and acute coronary heart disease events in non-insulin dependent diabetic and non-diabetic subjects in Finland.Eur. Heart J.17, 682–688 (1996).
  • Patel P , MendallMA, CarringtonDet al.: Association of helicobacter pylori and Chlamydia pneumoniae infections with coronary heart disease and cardiovascular risk factors.Br. Med. J.311, 711–714 (1995).
  • Ramirez JA : Isolation of Chlamydia pneumoniae from the coronary artery of a patient with coronary atherosclerosis. The Chlamydia pneumoniae/atherosclerosis study group.Ann. Intern. Med.125, 979–982 (1996).
  • Shor A , KuoCC, PattonDL: Detection of Chlamydia pneumoniae in coronary arterial fatty streaks and atheromatous plaques.S. Afr. Med. J.82, 158–161 (1992).
  • Thom DH , GraystonJT, SiscovickDS, WangSP, WeissNS, DalingJR: Association of prior infection with Chlamydia pneumoniae and angiographically demonstrated coronary artery disease.J. Am. Med. Assoc.268, 68–72 (1992).
  • Fabricant C , FabricantJ, LitrentaM, MinickC: Herpes-virus induced atherosclerosis. In: Viruses in Naturally Occurring Cancers. Essex M, Todara G, zur Hausen H (Eds). Cold Spring Harbor Laboratory, NY, USA, 7, 1251–1258 (1980).
  • Fabricant C , FabricantJ, LitrentaM, MinickC: Virus-induced atherosclerosis.J. Exp. Med.148, 335–340 (1978).
  • Saikku P , LeinonenM, MattilaKet al.: Serological evidence of an association of a novel chlamydia, twar, with chronic coronary heart disease and acute myocardial infarction.Lancet2, 983–986 (1988).
  • The Lipid Research Clinics Program: The lipid research clinics coronary primary prevention trial results. I. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering. J. Am. Med. Assoc.251, 365–374 (1984).
  • Benditt EP , BendittJM: Evidence for a monoclonal origin of human atherosclerotic plaques.Proc. Natl Acad. Sci. USA70, 1753–1756 (1973).
  • Brown MS , GoldsteinJL: A receptor-mediated pathway for cholesterol homeostasis.Science232, 34–47 (1986).
  • Arbustini E , MorbiniP, BelloBD, PratiF, SpecchiaG: From plaque biology to clinical setting.Am. Heart J.138, S55-S60 (1999).
  • Bhakdi S : Complement and atherogenesis: the unknown connection.Ann. Med.30, 503–507 (1998).
  • Ross R , GlomsetJA: The pathogenesis of atherosclerosis (first of two parts).N. Engl. J. Med.295, 369–377 (1976).
  • Ross R : Mechanisms of atherosclerosis – a review.Adv. Nephrol. Necker Hosp.19, 79–86 (1990).
  • Keaney J , GazianoJ, XuAet al.: Low-dose a-tocopherol improves and high-dose a-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits.J. Clin. Invest.93, 844–851 (1994).
  • Fish R , NabelE, SelwynAet al.: Response of coronary arteries of cardiac transplant patients to acetylcholine.J. Clin. Invest.81, 21–31 (1988).
  • Celermajer DS , SorensenKE, GoochVMet al.: Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis.Lancet340, 1111–1115 (1992).
  • Celermajer DS , AdamsMR, ClarksonPet al.: Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults.N. Engl. J. Med.334, 150–154 (1996).
  • Steinberg D , ParthasarathyS, CarewTE, KhooJC, WitztumJL: Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity.N. Engl. J. Med.320, 915–924 (1989).
  • Steinberg D : Thematic review series: The pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy: part ii: the early evidence linking hypercholesterolemia to coronary disease in humans.J. Lipid Res.46, 179–190 (2005).
  • Steinberg D : Thematic review series: the pathogenesis of atherosclerosis: an interpretive history of the cholesterol controversy, part III: mechanistically defining the role of hyperlipidemia.J. Lipid Res.46, 2037–2051 (2005).
  • Aengevaeren W : Beyond lipids – the role of the endothelium in coronary artery disease.Atherosclerosis147(Suppl. 1), S11–S16 (1999).
  • Stehouwer C : Is measurement of endothelial dysfunction useful.Eur. J. Clin. Invest.29, 459–461 (1999).
  • Raitakari O , CelermajerD: Testing for endothelial dysfunction.Ann. Med.32, 293–304 (1999).
  • Keaney JF Jr : Atherosclerosis: from lesion formation to plaque activation and endothelial dysfunction. Mol. Aspects Med.21, 99–166 (2000).
  • Hansen HH , VammenB, JensenMK: [Smoking cessation in patients with stable or unstable ischemic heart disease].Ugeskr. Laeg.161, 3659–3662 (1999).
  • Libby P , RidkerPM, MaseriA: Inflammation and atherosclerosis.Circulation105, 1135–1143 (2002).
  • Libby P , HanssonGK: Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions.Lab. Invest.64, 5–15 (1991).
  • Lopes-Virella MF , VirellaG: Atherosclerosis and autoimmunity.Clin. Immunol. Immunopathol.73, 155–167 (1994).
  • Lerman A , ZeiherAM: Endothelial function: cardiac events.Circulation111, 363–368 (2005).
  • Haegeli L , QuitzauK, LuescherTF: From endothelial dysfunction to clinical events: concept and update on the encore trials.Eur. Heart J. (Suppl. 3), B12–B19 (2001).
  • Sriraman R , TookeJE: Endothelial dysfunction and insulin resistance.Metab. Syndr. Relat. Disord.2, 129–136 (2004).
  • Pillarisetti S : Lipoprotein modulation of subendothelial heparan sulfate proteoglycans (perlecan) and atherogenicity.Trends Cardiovasc. Med.10, 60–65 (2000).
  • Kohler HP , GrantPJ: Plasminogen-activator inhibitor type 1 and coronary artery disease.N. Engl. J. Med.342, 1792–1801 (2000).
  • Esmon CT , XuJ, GuJMet al.: Endothelial protein c receptor.Thromb. Haemost.82, 251–258 (1999).
  • Esmon CT : The endothelial cell protein c receptor.Thromb. Haemost.83, 639–643 (2000).
  • Prescott SM , McIntyreTM, ZimmermanGA, StafforiniDM: Sol sherry lecture in thrombosis: molecular events in acute inflammation.Arterioscler. Thromb. Vasc. Biol.22, 727–733 (2002).
  • Dittman WA , MajerusPW: Structure and function of thrombomodulin: a natural anticoagulant.Blood75, 329–336 (1990).
  • Takanashi S , HasegawaY, KanehiraYet al.: Interleukin-10 level in sputum is reduced in bronchial asthma, COPD and in smokers.Eur. Respir. J.14, 309–314 (1999).
  • Moons AH , LeviM, PetersRJ: Tissue factor and coronary artery disease.Cardiovasc. Res.53, 313–325 (2002).
  • Polgar J , MatuskovaJ, WagnerDD: The p-selectin, tissue factor, coagulation triad.J. Thromb. Haemost.3, 1590–1596 (2005).
  • Muldowney JA, III, VaughanDE: Tissue-type plasminogen activator release: new frontiers in endothelial function. J. Am. Coll. Cardiol.40, 967–969 (2002).
  • Meyer D , GirmaJP: Von willebrand factor: structure and function.Thromb. Haemost.70, 99–104 (1993).
  • Vlot AJ , KoppelmanSJ, BoumaBN, SixmaJJ: Factor viii and von Willebrand factor.Thromb. Haemost.79, 456–465 (1998).
  • Mondino A , ResnatiM, BlasiF: Structure and function of the urokinase receptor.Thromb. Haemost.82(Suppl. 1), 19–22 (1999).
  • Grand R , TurnellA, GrabhamP: Cellular consequences of thrombin-receptor activation.Biochem. J.313, 353–368 (1996).
  • Bajaj MS , BirktoftJJ, SteerSA, BajajSP: Structure and biology of tissue factor pathway inhibitor.Thromb. Haemost.86, 959–972 (2001).
  • Reutelingsperger C : Annexins: Key regulators of haemostasis, thrombosis, and apoptosis.Thromb. Haemost.86, 413–419 (2001).
  • Lloyd-Jones DM , BlochKD: The vascular biology of nitric oxide and its role in atherogenesis.Annu. Rev. Med.47, 365–375 (1996).
  • Gewaltig MT , KojdaG: Vasoprotection by nitric oxide: mechanisms and therapeutic potential.Cardiovasc. Res.55, 250–260 (2002).
  • Brown JS , SteeleK: Cigarette smoking and random serum cholesterol levels in a Northern Ireland general practice population of 18- to 20-year-old students and non-students.Br. J. Gen. Pract.46, 665–669 (1996).
  • Barrow SE , WardPS, SleightholmMA, RitterJM, DolleryCT: Cigarette smoking: Profiles of thromboxane- and prostacyclin-derived products in human urine.Biochim. Biophys. Acta993, 121–127 (1989).
  • Kedzierski RM , YanagisawaM: Endothelin system: the double-edged sword in health and disease.Annu. Rev. Pharmacol. Toxicol.41, 851–876 (2001).
  • Best PJ , LermanA: Endothelin in cardiovascular disease: from atherosclerosis to heart failure.J. Cardiovasc. Pharmacol.35, S61–S63 (2000).
  • Palkhiwala SA , FrishmanWH, WarshafskyS: Bradykinin for the treatment of cardiovascular disease.Heart Dis.3, 333–339 (2001).
  • Shriver Z , LiuD, SasisekharanR: Emerging views of heparan sulfate glycosaminoglycan structure/activity relationships modulating dynamic biological functions.Trends Cardiovasc. Med.12, 71–77 (2002).
  • Waltenberger J : Modulation of growth factor action: implications for the treatment of cardiovascular diseases.Circulation96, 4083–4094 (1997).
  • Blobe GC , SchiemannWP, LodishHF: Role of transforming growth factor β in human disease.N. Engl. J. Med.342, 1350–1358 (2000).
  • Delafontaine P : Insulin-like growth factor I and its binding proteins in the cardiovascular system.Cardiovasc. Res.30, 825–834 (1995).
  • Bornstein P : Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1.J. Cell Biol.130, 503–506 (1995).
  • Breier G : Functions of the VEGF/VEGF receptor system in the vascular system.Semin. Thromb. Hemost.26, 553–559 (2000).
  • Bhakdi S , TorzewskiM, KloucheM, HemmesM: Complement and atherogenesis: Binding of crp to degraded, nonoxidized LDL enhances complement activation.Arterioscler. Thromb. Vasc. Biol.19, 2348–2354 (1999).
  • Carlos TM , HarlanJM: Leukocyte-endothelial adhesion molecules.Blood84, 2068–2101 (1994).
  • Cines DB , PollakES, BuckCAet al.: Endothelial cells in physiology and in the pathophysiology of vascular disorders.Blood91, 3527–3561 (1998).
  • Kharitonov SA , RobbinsRA, YatesD, KeatingsV, BarnesPJ: Acute and chronic effects of cigarette smoking on exhaled nitric oxide.Am. J. Respir. Crit. Care Med.152, 609–612 (1995).
  • Fernandez EJ , LolisE: Structure, function, and inhibition of chemokines.Annu. Rev. Pharmacol. Toxicol.42, 469–499 (2002).
  • Haddad JJ : Cytokines and related receptor-mediated signaling pathways.Biochem. Biophys. Res. Commun.297, 700–713 (2002).
  • Lasky LA : Selectins: Interpreters of cell-specific carbohydrate information during inflammation.Science258, 964–969 (1992).
  • Fukai T , FolzRJ, LandmesserU, HarrisonDG: Extracellular superoxide dismutase and cardiovascular disease.Cardiovasc. Res.55, 239–249 (2002).
  • Harms G , KraftR, GrelleG, VolzB, DerneddeJ, TauberR: Identification of nucleolin as a new l-selectin ligand.Biochem. J.360, 531–538 (2001).
  • Mashima R , WittingPK, StockerR: Oxidants and antioxidants in atherosclerosis.Curr. Opin. Lipidol.12, 411–418 (2001).
  • Mach F , SchonbeckU, SukhovaGKet al.: Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40–CD40 ligand signaling in atherosclerosis.Proc. Natl Acad. Sci. USA94, 1931–1936 (1997).
  • Brasier AR , RecinosA, III, EledrisiMS: Vascular inflammation and the renin–angiotensin system. Arterioscler. Thromb. Vasc. Biol.22, 1257–1266 (2002).
  • Laine P , PentikainenMO, WurznerRet al.: Evidence for complement activation in ruptured coronary plaques in acute myocardial infarction.Am. J. Cardiol.90, 404–408 (2002).
  • Gross PL , AirdWC: The endothelium and thrombosis.Semin. Thromb. Hemost.26, 463–478 (2000).
  • Gimbrone MA Jr : Endothelial dysfunction, hemodynamic forces, and atherosclerosis. Thromb. Haemost.82, 722–726 (1999).
  • Vanhoutte PM : Endothelial control of vasomotor function: from health to coronary disease.Circ. J.67, 572–575 (2003).
  • Hambrecht R , WolfA, GielenSet al.: Effect of exercise on coronary endothelial function in patients with coronary artery disease.N. Engl. J. Med.342, 454–460 (2000).
  • Zeiher AM , SchachingerV, MinnersJ: Long-term cigarette smoking impairs endothelium-dependent coronary arterial vasodilator function.Circulation92, 1094–1100 (1995).
  • Kunsch C , MedfordRM: Oxidative stress as a regulator of gene expression in the vasculature.Circ. Res.85, 753–766 (1999).
  • Dhalla NS , TemsahRM, NetticadanT: Role of oxidative stress in cardiovascular diseases.J. Hypertens.18, 655–673 (2000).
  • Cai H , HarrisonDG: Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress.Circ. Res.87, 840–844 (2000).
  • Horstman LL , JyW, JimenezJJ, AhnYS: Endothelial microparticles as markers of endothelial dysfunction.Front. Biosci.9, 1118–1135 (2004).
  • Jy W , JimenezJJ, ChengPet al.: Endothelial microaprticles (emp) bind and complex with unusually-large multimers of von Willebrand factor (ulvWF) and act as potent induceers of platelet adhesion and aggregation.Blood104, 997a (2004).
  • Jy W , MinagarA, JimenezJJet al.: Endothelial microparticles (emp) bind and activate monocytes: elevated emp-monocyte conjugates in multiple sclerosis.Front. Biosci.9, 3137–3144 (2004).
  • Sabatier F , RouxV, AnfossoF, CamoinL, SampolJ, Dignat-GeorgeF: Interaction of endothelial microparticles with monocytic cells in vitro induces tissue factor-dependent procoagulant activity.Blood99, 3962–3970 (2002).
  • Prescott SM , ZimmermanGA, McIntyreTM, StafforiniDM: Inflammation in the vascular wall as an early event in atherosclerosis.Diabetologia40(Suppl. 2), S111–S112 (1997).
  • Napoli C , LermanLO: Involvement of oxidation-sensitive mechanisms in the cardiovascular effects of hypercholesterolemia.Mayo. Clin. Proc.76, 619–631 (2001).
  • Napoli C , IgnarroLJ: Nitric oxide and atherosclerosis.Nitric Oxide5, 88–97 (2001).
  • Forstermann U , ClossEI, PollockJSet al.: Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions.Hypertension23, 1121–1131 (1994).
  • Morris SM Jr , BilliarTR: New insights into the regulation of inducible nitric oxide synthesis. Am. J. Physiol.266, E829–E839 (1994).
  • Nathan C , XieQW: Nitric oxide synthases: roles, tolls, and controls.Cell78, 915–918 (1994).
  • Boger RH , Bode-BogerSM, FrolichJC: The L-arginine-nitric oxide pathway: role in atherosclerosis and therapeutic implications.Atherosclerosis127, 1–11 (1996).
  • Hogg N , KalyanaramanB, JosephJ, StruckA, ParthasarathyS: Inhibition of low-density lipoprotein oxidation by nitric oxide. Potential role in atherogenesis.FEBS Lett.334, 170–174 (1993).
  • Cooke JP : Does adma cause endothelial dysfunction.Arterioscler. Thromb. Vasc. Biol.20, 2032–2037 (2000).
  • Rubanyi GM , VanhouttePM: Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor.Am. J. Physiol.250, H822–H827 (1986).
  • Abu-Soud HM , HazenSL: Nitric oxide is a physiological substrate for mammalian peroxidases.J. Biol. Chem.275, 37524–37532 (2000).
  • Pou S , PouWS, BredtDS, SnyderSH, RosenGM: Generation of superoxide by purified brain nitric oxide synthase.J. Biol. Chem.267, 24173–24176 (1992).
  • Stroes E , de Bruin T, de Valk H et al.: No activity in familial combined hyperlipidemia: potential role of cholesterol remnants. Cardiovasc. Res.36, 445–452 (1997).
  • Xia Y , RomanLJ, MastersBS, ZweierJL: Inducible nitric-oxide synthase generates superoxide from the reductase domain.J. Biol. Chem.273, 22635–22639 (1998).
  • Pritchard KA Jr , Groszek L, Smalley DM et al.: Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion. Circ. Res.77, 510–518 (1995).
  • Vasquez-Vivar J , KalyanaramanB, MartasekPet al.: Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors.Proc. Natl Acad. Sci. USA95, 9220–9225 (1998).
  • Moncada S , PalmerRM, HiggsEA: Nitric oxide: physiology, pathophysiology, and pharmacology.Pharmacol. Rev.43, 109–142 (1991).
  • Kubes P , SuzukiM, GrangerDN: Nitric oxide: an endogenous modulator of leukocyte adhesion.Proc. Natl Acad. Sci. USA88, 4651–4655 (1991).
  • Radomski MW , PalmerRM, MoncadaS: An L-arginine/nitric oxide pathway present in human platelets regulates aggregation.Proc. Natl Acad. Sci. USA87, 5193–5197 (1990).
  • Ginnan R , GuikemaBJ, HalliganKE, SingerHA, Jourd‘heuilD: Regulation of smooth muscle by inducible nitric oxide synthase and nadph oxidase in vascular proliferative diseases.Free Radic. Biol. Med.44, 1232–1245 (2008).
  • Hansson GK , GengYJ, HolmJ, HardhammarP, WennmalmA, JennischeE: Arterial smooth muscle cells express nitric oxide synthase in response to endothelial injury.J. Exp. Med.180, 733–738 (1994).
  • Kibbe M , BilliarT, TzengE: Inducible nitric oxide synthase and vascular injury.Cardiovasc. Res.43, 650–657 (1999).
  • Ku DN , GiddensDP, ZarinsCK, GlagovS: Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress.Arteriosclerosis5, 293–302 (1985).
  • Gnasso A , CaralloC, IraceCet al.: Association between intima-media thickness and wall shear stress in common carotid arteries in healthy male subjects.Circulation94, 3257–3262 (1996).
  • Sessa WC , PritchardK, SeyediN, WangJ, HintzeTH: Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression.Circ. Res.74, 349–353 (1994).
  • Blair SN , KohlHWIII, BarlowCE, PaffenbargerRSJr, GibbonsLW, MaceraCA: Changes in physical fitness and all-cause mortality. A prospective study of healthy and unhealthy men. J. Am. Med. Assoc.273, 1093–1098 (1995).
  • Salonen JT , PuskaP, TuomilehtoJ: Physical activity and risk of myocardial infarction, cerebral stroke and death: a longitudinal study in eastern finland.Am. J. Epidemiol.115, 526–537 (1982).
  • Davies MJ , ThomasAC: Plaque fissuring – the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina.Br. Heart J.53, 363–373 (1985).
  • Higashi Y , SasakiS, KurisuSet al.: Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects: role of endothelium-derived nitric oxide.Circulation100, 1194–1202 (1999).
  • Glagov S , WeisenbergE, ZarinsCK, StankunaviciusR, KolettisGJ: Compensatory enlargement of human atherosclerotic coronary arteries.N. Engl. J. Med.316, 1371–1375 (1987).
  • Hambrecht R , HilbrichL, ErbsSet al.: Correction of endothelial dysfunction in chronic heart failure: additional effects of exercise training and oral L-arginine supplementation.J. Am. Coll. Cardiol.35, 706–713 (2000).
  • Rudic RD , SheselyEG, MaedaN, SmithiesO, SegalSS, SessaWC: Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling.J. Clin. Invest.101, 731–736 (1998).
  • Niebauer J , CookeJP: Cardiovascular effects of exercise: role of endothelial shear stress.J. Am. Coll. Cardiol.28, 1652–1660 (1996).
  • Clarkson P , MontgomeryH, MullenMet al.: Exercise training enhances endothelial function in young men.J. Am. Coll. Cardiol.33, 1379–1385 (1999).
  • Langille BL , O‘DonnellF: Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent.Science231, 405–407 (1986).
  • Bucher HC , GriffithLE, GuyattGH: Systematic review on the risk and benefit of different cholesterol-lowering interventions.Arterioscler. Thromb. Vasc. Biol.19, 187–195 (1999).
  • Stamler J , WentworthD, NeatonJ: Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT).J. Am. Med. Assoc.256, 2823–2828 (1986).
  • Brotons C , RiberaA, PerichRet al.: Worldwide distribution of blood lipids and lipoproteins in childhood and adolescence: a review study.Atherosclerosis139, 1–9 (1998).
  • Stein E : Laboratory surrogates for anti-atherosclerotic drug development.Am. J. Cardiol.87, 21A–26A (2001).
  • Williams KJ , TabasI: The response-to-retention hypothesis of early atherogenesis.Arterioscler. Thromb. Vasc. Biol.15, 551–561 (1995).
  • Steinberg D : Antioxidants in the prevention of human atherosclerosis. Summary of the proceedings of a national heart, lung, and blood institute workshop: September 5–6, 1991, Bethesda, Maryland.Circulation85, 2337–2344 (1992).
  • Esterbauer H , RamosP: Chemistry and pathophysiology of oxidation of LDL.Rev. Physiol. Biochem. Pharmacol.127, 31–64 (1996).
  • Steinberg D : Low density lipoprotein oxidation and its pathobiological significance.J. Biol. Chem.272, 20963–20966 (1997).
  • Ok E , BasnakianAG, ApostolovEO, BarriYM, ShahSV: Carbamylated low-density lipoprotein induces death of endothelial cells: a link to atherosclerosis in patients with kidney disease.Kidney. Int.68, 173–178 (2005).
  • Asci G , BasciA, ShahSVet al.: Carbamylated low-density lipoprotein induces proliferation and increases adhesion molecule expression of human coronary artery smooth muscle cells.Nephrology (Carlton)13, 480–486 (2008).
  • Horkko S , SavolainenMJ, KervinenK, KesaniemiYA: Carbamylation-induced alterations in low-density lipoprotein metabolism.Kidney. Int.41, 1175–1181 (1992).
  • Loria V , DatoI, GrazianiF, BiasucciLM: Myeloperoxidase: a new biomarker of inflammation in ischemic heart disease and acute coronary syndromes.Mediators Inflamm.2008, 135625 (2008).
  • Shao B , OdaMN, OramJF, HeineckeJW: Myeloperoxidase: an inflammatory enzyme for generating dysfunctional high density lipoprotein.Curr. Opin. Cardiol.21, 322–328 (2006).
  • Malle E , MarscheG, ArnholdJ, DaviesMJ: Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid.Biochim. Biophys. Acta1761, 392–415 (2006).
  • Sirpal S : Myeloperoxidase-mediated lipoprotein carbamylation as a mechanistic pathway for atherosclerotic vascular disease.Clin. Sci.116, 681–695 (2009).
  • Nicholls SJ , HazenSL: Myeloperoxidase and cardiovascular disease.Arterioscler. Thromb. Vasc. Biol.25, 1102–1111 (2005).
  • Wang Z , NichollsSJ, RodriguezERet al.: Protein carbamylation links inflammation, smoking, uremia and atherogenesis.Nat. Med.13, 1176–1184 (2007).
  • Stary HC , ChandlerAB, GlagovSet al.: A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the committee on vascular lesions of the council on arteriosclerosis, American Heart Association.Arterioscler. Thromb.14, 840–856 (1994).
  • Ridker PM , HennekensCH, BuringJE, RifaiN: C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women.N. Engl. J. Med.342, 836–843 (2000).
  • Lusis AJ : Atherosclerosis.Nature407, 233–241 (2000).
  • Imai T , NishimuraM, NankiT, UmeharaH: [Fractalkine and inflammatory diseases].Nihon Rinsho Meneki Gakkai Kaishi28, 131–139 (2005).
  • Debette S , BevanS, DartiguesJFet al.: Fractalkine receptor/ligand genetic variants and carotid intima-media thickness.Stroke40, 2212–2214 (2009).
  • McComb JG , RanganathanM, LiuXHet al.: Cx3cl1 up-regulation is associated with recruitment of cx3cr1+ mononuclear phagocytes and T lymphocytes in the lungs during cigarette smoke-induced emphysema.Am. J. Pathol.173, 949–961 (2008).
  • Moatti D , FaureS, FumeronFet al.: Polymorphism in the fractalkine receptor cx3cr1 as a genetic risk factor for coronary artery disease.Blood97, 1925–1928 (2001).
  • Mosmann TR , SadS: The expanding universe of T-cell subsets: th1, th2 and more.Immunol. Today17, 138–146 (1996).
  • Villa-Colinayo V , ShiW, AraujoJ, LusisAJ: Genetics of atherosclerosis: the search for genes acting at the level of the vessel wall.Curr. Atheroscler. Rep.2, 380–389 (2000).
  • Celermajer DS , SorensenKE, GeorgakopoulosDet al.: Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults.Circulation88, 2149–2155 (1993).
  • Kojda G , BeckJK, MeyerW, NoackE: Nitrovasodilator-induced relaxation and tolerance development in porcine vena cordis magna: dependence on intact endothelium.Br. J. Pharmacol.112, 533–540 (1994).
  • Moreno HJ , ChalonS, UraeAet al.: Endothelial dysfunction in human hand veins is rapidly reversible after smoking cessation.Am. J. Physiol.275, H1040–H1045 (1998).
  • Bonetti PO , PumperGM, HiganoST, HolmesDRJr, KuvinJT, LermanA: Noninvasive identification of patients with early coronary atherosclerosis by assessment of digital reactive hyperemia. J. Am. Coll. Cardiol.44, 2137–2141 (2004).
  • Kuvin JT , PatelAR, SlineyKAet al.: Assessment of peripheral vascular endothelial function with finger arterial pulse wave amplitude.Am. Heart J.146, 168–174 (2003).
  • De Caterina R : Endothelial dysfunctions: Common denominators in vascular disease.Curr. Opin. Clin. Nutr. Metab. Care3, 453–467 (2000).
  • Blann A , McCollumC, LipG: Relationship between plasma markers of endothelial cell integrity and the framingham cardiovascular disease risk-factor scores in apparently healthy individuals.Blood Coagul. Fibrinolysis13, 513–518 (2002).
  • Blann AD , LipGY, McCollumCN: Changes in von Willebrand factor and soluble icam, but not soluble vcam, soluble e selectin or soluble thrombomodulin, reflect the natural history of the progression of atherosclerosis.Atherosclerosis165, 389–391 (2002).
  • Hamsten A , de Faire U, Walldius G et al.: Plasminogen activator inhibitor in plasma: risk factor for recurrent myocardial infarction. Lancet2, 3–9 (1987).
  • Hamsten A , WimanB, de FaireU, BlombackM: Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction. N. Engl. J. Med.313, 1557–1563 (1985).
  • Sobel BE : Increased plasminogen activator inhibitor-1 and vasculopathy. A reconcilable paradox.Circulation99, 2496–2498 (1999).
  • Binder B : Physiology and pathophysiology of the fibrinolytic system.Fibrinolysis9(Suppl. 1), 3–8 (1995).
  • Macy EM , MeilahnEN, DeclerckPJ, TracyRP: Sample preparation for plasma measurement of plasminogen activator inhibitor-1 antigen in large population studies.Arch. Pathol. Lab. Med.117, 67–70 (1993).
  • Eliasson M , EvrinP, LundbladD, AsplundK, RanbyM: Influence of gender, age, and sampling time on plasma fibrinolytic variables and fibrinogen – a population study.Fibrinolysis7, 316–323 (1993).
  • Nguyen ND , GhaddarH, StinsonV, ChamblessLE, WuKK: ARIC hemostasis study-iv. Intraindividual variability and reliability of hemostatic factors. The Atherosclerosis Risk in Communities (ARIC).Thromb. Haemost.73, 256–260 (1995).
  • Woodhouse PR , MeadeTW, KhawKT: Plasminogen activator inhibitor-1, the acute phase response and vitamin c.Atherosclerosis133, 71–76 (1997).
  • Blomback B : Fibrinogen and fibrin – proteins with complex roles in hemostasis and thrombosis.Thromb. Res.83, 1–75 (1996).
  • Kannel WB , D‘AgostinoRB, BelangerAJ: Fibrinogen, cigarette smoking, and risk of cardiovascular disease: insights from the Framingham study.Am. Heart J.113, 1006–1010 (1987).
  • Ma J , HennekensCH, RidkerPM, StampferMJ: A prospective study of fibrinogen and risk of myocardial infarction in the physicians‘ health study.J. Am. Coll. Cardiol.33, 1347–1352 (1999).
  • Woodward M , LoweGD, RumleyA, Tunstall-PedoeH: Fibrinogen as a risk factor for coronary heart disease and mortality in middle-aged men and women. The Scottish Heart Health Study.Eur. Heart J.19, 55–62 (1998).
  • Wu LL : Review of risk factors for cardiovascular diseases.Ann. Clin. Lab. Sci.29, 127–133 (1999).
  • Margaglione M , CappucciG, ColaizzoDet al.: Fibrinogen plasma levels in an apparently healthy general population – relation to environmental and genetic determinants.Thromb. Haemost.80, 805–810 (1998).
  • Cook NS , UbbenD: Fibrinogen as a major risk factor in cardiovascular disease.Trends Pharmacol. Sci.11, 444–451 (1990).
  • Hackam DG , AnandSS: Emerging risk factors for atherosclerotic vascular disease: a critical review of the evidence.J. Am. Med. Assoc.290, 932–940 (2003).
  • Hansson G : Immune mechanisms in atherosclerosis.Arterioscler. Thromb. Vasc. Biol.21, 1876–1890 (2001).
  • Getz GS : Thematic review series: the immune system and atherogenesis. Immune function in atherogenesis.J. Lipid Res.46, 1–10 (2005).
  • Parkin J , CohenB: An overview of the immune system.Lancet357, 1777–1789 (2001).
  • Tobias P , CurtissLK: Thematic review series: the immune system and atherogenesis. Paying the price for pathogen protection: Toll receptors in atherogenesis.J. Lipid Res.46, 404–411 (2005).
  • Urbich C , DimmelerS: CD40 and vascular inflammation.Can. J. Cardiol.20, 681–683 (2004).
  • Phipps RP : Atherosclerosis: the emerging role of inflammation and the CD40–CD40 ligand system.Proc. Natl Acad. Sci. USA97, 6930–6932 (2000).
  • Heeschen C , DimmelerS, HammCWet al.: Soluble cd40 ligand in acute coronary syndromes.N. Engl. J. Med.348, 1104–1111 (2003).
  • MacPhee CH : Lipoprotein-associated phospholipase A2, a potential new risk factor for coronary artery disease and a therapeutic target.Curr. Opin. Pharmacol.1, 121–125 (2001).
  • MacPhee CH , MooresKE, BoydHFet al.: Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor.Biochem. J.338(Pt 2), 479–487 (1999).
  • Prescott SM , ZimmermanGA, StafforiniDM, McIntyreTM: Platelet-activating factor and related lipid mediators.Annu. Rev. Biochem.69, 419–445 (2000).
  • Ostermann G , LangA, HoltzH, RuhlingK, WinklerL, TillU: The degradation of platelet-activating factor in serum and its discriminative value in atherosclerotic patients.Thromb. Res.52, 529–540 (1988).
  • Hurt-Camejo E , AndersenS, StandalRet al.: Localization of nonpancreatic secretory phospholipase A2 in normal and atherosclerotic arteries. Activity of the isolated enzyme on low-density lipoproteins.Arterioscler. Thromb. Vasc. Biol.17, 300–309 (1997).
  • Hurt-Camejo E , CamejoG: Potential involvement of type ii phospholipase A2 in atherosclerosis.Atherosclerosis132, 1–8 (1997).
  • Chait A , HanCY, OramJF, HeineckeJW: Thematic review series: the immune system and atherogenesis. Lipoprotein-associated inflammatory proteins: markers or mediators of cardiovascular disease.J. Lipid Res.46, 389–403 (2005).
  • Ridker PM , RifaiN, RoseL, BuringJE, CookNR: Comparison of c-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events.N. Engl. J. Med.347, 1557–1565 (2002).
  • Pepys M , HirschfieldG: C-reactive protein: A critical update.J. Clin. Invest.111, 1805–1812 (2001).
  • Armani A , BeckerRC: The biology, utilization, and attenuation of c-reactive protein in cardiovascular disease: part I.Am. Heart J.149, 971–976 (2005).
  • Armani A , BeckerRC: The biology, utilization, and attenuation of c-reactive protein in cardiovascular disease: part ii.Am. Heart J.149, 977–983 (2005).
  • Ridker PM , DanielsonE, FonsecaFAet al.: Rosuvastatin to prevent vascular events in men and women with elevated c-reactive protein.N. Engl. J. Med.359, 2195–2207 (2008).
  • Daugherty A , DunnJL, RateriDL, HeineckeJW: Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.J. Clin. Invest.94, 437–444 (1994).
  • Brennan M , PennM, Van Lente F et al.: Prognostic value of myeloperoxidase in patients with chest pain. N. Engl. J. Med.349, 1595–1604 (2003).
  • Baldus S , HeeschenC, MeinertzTet al.: Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes.Circulation108, 1440–1445 (2003).
  • Biasucci LM , D‘OnofrioG, LiuzzoGet al.: Intracellular neutrophil myeloperoxidase is reduced in unstable angina and acute myocardial infarction, but its reduction is not related to ischemia.J. Am. Coll. Cardiol.27, 611–616 (1996).
  • Gerdes N , SukhovaGK, LibbyP, ReynoldsRS, YoungJL, SchonbeckU: Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis.J. Exp. Med.195, 245–257 (2002).
  • Tenger C , SundborgerA, JawienJ, ZhouX: IL-18 accelerates atherosclerosis accompanied by elevation of IFN-γ and CXCL16 expression independently of T cells.Arterioscler. Thromb. Vasc. Biol.25, 791–796 (2005).
  • Blankenberg S , LucG, DucimetierePet al.: Interleukin-18 and the risk of coronary heart disease in european men: the prospective epidemiological study of myocardial infarction (prime).Circulation108, 2453–2459 (2003).
  • Blankenberg S , TiretL, BickelCet al.: Interleukin-18 is a strong predictor of cardiovascular death in stable and unstable angina.Circulation106, 24–30 (2002).
  • Frenette PS , WagnerDD: Adhesion molecules – part I.N. Engl. J. Med.334, 1526–1529 (1996).
  • Frenette PS , WagnerDD: Adhesion molecules – part II: blood vessels and blood cells.N. Engl. J. Med.335, 43–45 (1996).
  • Jang Y , LincoffAM, PlowEF, TopolEJ: Cell adhesion molecules in coronary artery disease.J. Am. Coll. Cardiol.24, 1591–1601 (1994).
  • Adams DH , LloydAR: Chemokines: leucocyte recruitment and activation cytokines.Lancet349, 490–495 (1997).
  • Springer T , CybulskiM: Traffic signals on endothelium for leucocytes in health, inflammation, and atherosclerosis. In: Atherosclerosis and Coronary Artery Disease. Fuster V, Ross R, Topol E (Eds). Lippincott-Raven, PA, USA, Chapter29, 511–537 (1996).
  • Mulvihill NT , FoleyJB, CreanP, WalshM: Prediction of cardiovascular risk using soluble cell adhesion molecules.Eur. Heart J.23, 1569–1574 (2002).
  • Blankenberg S , RupprechtHJ, BickelCet al.: Circulating cell adhesion molecules and death in patients with coronary artery disease.Circulation104, 1336–1342 (2001).
  • Cimminiello C , ToschiV: Atherothrombosis: The role of platelets.Eur. Heart J.20(Suppl. A), A8–A13 (1999).
  • Prentice C : Platelets and atherosclerosis.Eur. Heart J.20(Suppl. A), A3–A7 (1999).
  • Entman ML BC: Association of neutrophils with platelet aggregates in unstable angina. Should we alter therapy. Circulation94, 1206–1208 (1996).
  • Fateh-Moghadam S , ErselS, BockschWet al.: Platelet degranulation is associated with progression of intima-media thickness of the common carotid artery in patients with diabetes mellitus Type 2.Arterioscler. Thromb. Vasc. Biol.25, 1299–1303 (2005).
  • Maresca G , Di BlasioA, MarchioliR, Di MinnoG: Measuring plasma fibrinogen to predict stroke and myocardial infarction: an update. Arterioscler. Thromb. Vasc. Biol.19, 1368–1377 (1999).
  • Frohlich M , SundM, LowelH, ImhofA, HoffmeisterA, KoenigW: Independent association of various smoking characteristics with markers of systemic inflammation in men. Results from a representative sample of the general population (Monica Augsburg survey 1994/95).Eur. Heart J.24(Suppl. A), 1365–1372 (2003).
  • Schwartz SM , deBloisD, O‘BrienER: The intima. Soil for atherosclerosis and restenosis.Circ. Res.77, 445–465 (1995).
  • Schwartz SM , MurryCE: Proliferation and the monoclonal origins of atherosclerotic lesions.Annu. Rev. Med.49, 437–460 (1998).
  • Cercek B , YamashitaM, DimayugaPet al.: Nuclear factor-κb activity and arterial response to balloon injury.Atherosclerosis131, 59–66 (1997).
  • Landry DB , CouperLL, BryantSR, LindnerV: Activation of the NF-κb and Iκb system in smooth muscle cells after rat arterial injury. Induction of vascular cell adhesion molecule-1 and monocyte chemoattractant protein-1.Am. J. Pathol.151, 1085–1095 (1997).
  • Bu DX , ErlW, de MartinR, HanssonGK, YanZQ: Ikkβ-dependent NF-κb pathway controls vascular inflammation and intimal hyperplasia. FASEB J.19, 1293–1295 (2005).
  • Rainer D , HoethM, Hofer-WarbinekR, SchmidL: The transcription factor NF-κb and the regulation of vascular cell function.Arteroscler. Thromb. Vasc. Biol.20, e83–e88 (2000).
  • Lindner V , LappiDA, BairdA, MajackRA, ReidyMA: Role of basic fibroblast growth factor in vascular lesion formation.Circ. Res.68, 106–113 (1991).
  • Fingerle J , JohnsonR, ClowesA, MajeskyM, ReidyM: Role of platelets in smooth muscle cell proliferation and migration after vascular injury in rat carotid artery.Proc. Natl Acad. Sci. USA86, 8412–8416 (1989).
  • Liau G , ChanL: Regulation of extracellular matrix RNA levels in cultured smooth muscle cells. Relationship to cellular quiescence.J. Biol. Chem.264, 10315–10320 (1989).
  • Hamon M , BautersC, McFaddenEPet al.: Restenosis after coronary angioplasty.Eur. Heart J.16(Suppl. I), 33–48 (1995).
  • Davies M , HagenP: Pathobiology of intimal hyperplasia.Br. J. Surg.81, 1254–1269 (1994).
  • Libby P , SchwartzD, BrogiE, TanakaH, ClintonS: A cascade model for restenosis. A special case for atherosclerosis progression.Circulation86, 47–52 (1992).
  • Tell GS , PolakJF, WardBJ, KittnerSJ, SavagePJ, RobbinsJ: Relation of smoking with carotid artery wall thickness and stenosis in older adults. The Cardiovascular Health Sudy. The Cardiovascular Health Study (CHS) collaborative research group.Circulation90, 2905–2908 (1994).
  • Howard G , WagenknechtLE, BurkeGLet al.: Cigarette smoking and progression of atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) study.J. Am. Med. Assoc.279, 119–124 (1998).
  • Sanders M : Molecular and cellular concepts in atherosclerosis.Pharmacol. Ther.61, 109–153 (1994).
  • Libby P : Molecular bases of the acute coronary syndromes.Circulation91, 2844–2850 (1995).

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