57
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Decreased Level of Serum Autoantibody Against LG72 is a Biosignature of Amyotrophic Lateral Sclerosis

, , , &
Pages 73-79 | Published online: 17 Dec 2015

References

  • Worms PM . The epidemiology of motor neuron diseases: a review of recent studies. J. Neurol. Sci.191(1–2), 3–9 (2001).
  • Mitchell JD , BorasioGD. Amyotrophic lateral sclerosis. Lancet369(9578), 2031–2041 (2007).
  • Dettmers C , FatepourD, FaustH, JerusalemF. Sympathetic skin response abnormalities in amyotrophic lateral sclerosis. Muscle Nerve16(9), 930–934 (1993).
  • Oey PL , VosPE, WienekeGH, WokkeJH, BlankestijnPJ, KaremakerJM. Subtle involvement of the sympathetic nervous system in amyotrophic lateral sclerosis. Muscle Nerve25(3), 402–408 (2002).
  • Hsueh KW , HsiehAC, HarnHJ, LinSZ. Stem cell therapy in amyotrophic lateral sclerosis. BioMedicine2(2), 58–63 (2012).
  • Huang JL , ChangHT, ChengR, HsuHH, PaiTW. Identification of simple sequence repeat biomarkers through cross-species comparison in a tag cloud representation. BioMed Res. Int.2014, 678971 (2014).
  • Chang H-T , LoY-Y, HuangJ-L, LinW-Y, PaiT-W. Cross-species identification of in silico microsatellite biomarkers for genetic disease. BioMedicine4(2), 47–50 (2014).
  • Liu GT , HwangCS, HsiehCHet al. Eosinophil-derived neurotoxin is elevated in patients with amyotrophic lateral sclerosis. Mediators Inflamm.2013, 421389 (2013).
  • Al-Chalabi A , LeighPN. Recent advances in amyotrophic lateral sclerosis. Curr. Opin. Neurol.13(4), 397–405 (2000).
  • Conwit RA . Preventing familial ALS: a clinical trial may be feasible but is an efficacy trial warranted?J. Neurol. Sci.251(1–2), 1–2 (2006).
  • Hwang SC , HsiehCH, LiuGT, ChenSY, TschenJS, ChangHT. Molecular biomarkers for amyotrophic lateral sclerosis. Curr. Bioinform.8(1), 87–92 (2013).
  • Bergeron C . Oxidative stress: its role in the pathogenesis of amyotrophic lateral sclerosis. J. Neurol. Sci.129(Suppl.), 81–84 (1995).
  • Siddique T , DengHX. Genetics of amyotrophic lateral sclerosis. Hum. Mol. Genet.5, 1465–1470 (1996).
  • Gurney ME , PuH, ChiuAYet al. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science264(5166), 1772–1775 (1994).
  • Liu D , WenJ, LiuJ, LiL. The roles of free radicals in amyotrophic lateral sclerosis: reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids. FASEB J.13(15), 2318–2328 (1999).
  • Appel SH , EngelhardtJI, GarciaJ, StefaniE. Autoimmunity and ALS: a comparison of animal models of immune-mediated motor neuron destruction and human ALS. Adv. Neurol.56, 405–412 (1991).
  • Couratier P , YiFH, Preud’hommeJLet al. Serum autoantibodies to neurofilament proteins in sporadic amyotrophic lateral sclerosis. J. Neurol. Sci.154(2), 137–145 (1998).
  • Engelhardt JI , AppelSH, KillianJM. Motor neuron destruction in guinea pigs immunized with bovine spinal cord ventral horn homogenate: experimental autoimmune gray matter disease. J. Neuroimmunol.27(1), 21–31 (1990).
  • Duarte F , BinetS, LacomblezL, BoucheP, Preud’hommeJL, MeiningerV. Quantitative analysis of monoclonal immunoglobulins in serum of patients with amyotrophic lateral sclerosis. J. Neurol. Sci.104(1), 88–91 (1991).
  • Rowland LP , DefendiniR, ShermanWet al. Macroglobulinemia with peripheral neuropathy simulating motor neuron disease. Ann. Neurol.11(5), 532–536 (1982).
  • Chumakov I , BlumenfeldM, GuerassimenkoOet al. Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia. Proc. Natl. Acad. Sci. USA99(21), 13675–13680 (2002).
  • Pollegioni L , PiubelliL, SacchiS, PiloneMS, MollaG. Physiological functions of D-amino acid oxidases: from yeast to humans. Cell. Mol. Life Sci.64(11), 1373–1394 (2007).
  • Romano D , MollaG, PollegioniL, MarinelliF. Optimization of human D-amino acid oxidase expression in Escherichia coli. Protein Expr. Purif.68(1), 72–78 (2009).
  • Chang SL , HsiehCH, ChenYJet al. The C-terminal region of G72 increases D-amino acid oxidase activity. Int. J. Mol. Sci.15(1), 29–43 (2014).
  • Kvajo M , DhillaA, SworDE, KarayiorgouM, GogosJA. Evidence implicating the candidate schizophrenia/bipolar disorder susceptibility gene G72 in mitochondrial function. Mol. Psychiatry13(7), 685–696 (2008).
  • Wang M , ChenHJ, ZhangJ, LiWM, XieX, ChangHT. Identification of pLG72-induced oxidative stress using systemic approaches. BioMed Res. Int.2015, 429253 (2015).
  • Otte DM , SommersbergB, KudinAet al. N-acetyl cysteine treatment rescues cognitive deficits induced by mitochondrial dysfunction in G72/G30 transgenic mice. Neuropsychopharmacology36(11), 2233–2243 (2011).
  • Hwang CS , LiuGT, ChangMD, LiaoIL, ChangHT. Elevated serum autoantibody against high mobility group box 1 as a potent surrogate biomarker for amyotrophic lateral sclerosis. Neurobiol. Dis.58, 13–18 (2013).
  • Goldberg TE , StraubRE, CallicottJHet al. The G72/G30 gene complex and cognitive abnormalities in schizophrenia. Neuropsychopharmacology31(9), 2022–2032 (2006).
  • Mossner R , SchuhmacherA, WagnerMet al. DAOA/G72 predicts the progression of prodromal syndromes to first episode psychosis. Eur. Arch. Psychiatry Clin. Neurosci.260(3), 209–215 (2010).
  • James DI , ParonePA, MattenbergerY, MartinouJC. hFis1, a novel component of the mammalian mitochondrial fission machinery. J. Biol. Chem.278(38), 36373–36379 (2003).
  • Chen H , ChomynA, ChanDC. Disruption of fusion results in mitochondrial heterogeneity and dysfunction. J. Biol. Chem.280(28), 26185–26192 (2005).
  • Siciliano G , D’avinoC, Del CoronaAet al. Impaired oxidative metabolism and lipid peroxidation in exercising muscle from ALS patients. Amyotroph. Lateral Scler. Other Motor Neuron Disord.3(2), 57–62 (2002).
  • Cataldo AM , McphieDL, LangeNTet al. Abnormalities in mitochondrial structure in cells from patients with bipolar disorder. Am. J. Pathol.177(2), 575–585 (2010).
  • Shao L , MartinMV, WatsonSJet al. Mitochondrial involvement in psychiatric disorders. Ann. Med.40(4), 281–295 (2008).
  • Zhang XY , TanYL, ZhouDFet al. Disrupted antioxidant enzyme activity and elevated lipid peroxidation products in schizophrenic patients with tardive dyskinesia. J. Clin. Psychiatry68(5), 754–760 (2007).
  • Do KQ , TrabesingerAH, Kirsten-KrugerMet al. Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo. Eur. J. Neurosci.12(10), 3721–3728 (2000).
  • Zhang XY , TanYL, CaoLYet al. Antioxidant enzymes and lipid peroxidation in different forms of schizophrenia treated with typical and atypical antipsychotics. Schizophr. Res.81(2–3), 291–300 (2006).
  • Hwang CS , WengHH, WangLF, TsaiCH, ChangHT. An eye-tracking assistive device improves the quality of life for ALS patients and reduces the caregivers’ burden. J. Mot. Behav.46(4), 233–238 (2014).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.