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Editorial

CpG-specific methylation at rheumatoid arthritis diagnosis as a marker of treatment response

, &
Pages 595-597 | Received 17 Jan 2017, Accepted 02 Feb 2017, Published online: 27 Apr 2017

References

  • Neidhart M , RethageJ , KuchenSet al. Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression . Arthritis Rheum.43 ( 12 ), 2634 – 2647 ( 2000 ).
  • Karouzakis E , RengelY , JungelAet al. DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts . Genes Immun.12 ( 8 ), 643 – 652 ( 2011 ).
  • Nakano K , WhitakerJW , BoyleDL , WangW , FiresteinGS . DNA methylome signature in rheumatoid arthritis . Ann. Rheum. Dis.72 ( 1 ), 110 – 117 ( 2013 ).
  • Nile CJ , ReadRC , AkilM , DuffGW , WilsonAG . Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis . Arthritis Rheum.58 ( 9 ), 2686 – 2693 ( 2008 ).
  • Bui C , BarterMJ , ScottJLet al. cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis . FASEB J.26 ( 7 ), 3000 – 3011 ( 2012 ).
  • Heyn H , EstellerM . DNA methylation profiling in the clinic: applications and challenges . Nat. Rev. Genet.13 ( 10 ), 679 – 692 ( 2012 ).
  • Reynolds GP , FachimHA . Does DNA methylation influence the effects of psychiatric drugs?Epigenomics8 ( 3 ), 309 – 312 ( 2016 ).
  • Glossop JR , NixonNB , EmesRDet al. DNA methylation at diagnosis is associated with response to disease-modifying drugs in early rheumatoid arthritis . Epigenomics doi:10.2217/epi-2016–0042 ( 2016 ) ( Epub ahead of print ).
  • Farragher TM , LuntM , FuB , BunnD , SymmonsDP . Early treatment with, and time receiving, first disease-modifying antirheumatic drug predicts long-term function in patients with inflammatory polyarthritis . Ann. Rheum. Dis.69 ( 4 ), 689 – 695 ( 2010 ).
  • Barres R , YanJ , EganBet al. Acute exercise remodels promoter methylation in human skeletal muscle . Cell Metab.15 ( 3 ), 405 – 411 ( 2012 ).
  • Lane SC , CameraDM , LassiterDGet al. Effects of sleeping with reduced carbohydrate availability on acute training responses . J. Appl. Physiol. (1985)119 ( 6 ), 643 – 655 ( 2015 ).
  • O’Reilly S . MicroRNAs in fibrosis: opportunities and challenges . Arthritis Res. Ther.18 , 11 ( 2016 ).
  • Altorok N , TsouPS , CoitP , KhannaD , SawalhaAH . Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies . Ann. Rheum. Dis.74 ( 8 ), 1612 – 1620 ( 2015 ).
  • Varga J , PascheB . Transforming growth factor beta as a therapeutic target in systemic sclerosis . Nat. Rev. Rheumatol.5 ( 4 ), 200 – 206 ( 2009 ).
  • Gras C , RatusznyD , HadamitzkyC , ZhangH , BlasczykR , FigueiredoC . miR-145 contributes to hypertrophic scarring of the skin by inducing myofibroblast activity . Mol. Med.21 , 296 – 304 ( 2015 ).
  • Ciechomska M , O’ReillyS , SuwaraM , Bogunia-KubikK , van LaarJM . MiR-29a reduces TIMP-1 production by dermal fibroblasts via targeting TGF-beta activated kinase 1 binding protein 1, implications for systemic sclerosis . PLoS ONE9 ( 12 ), e115596 ( 2014 ).
  • Maurer B , StanczykJ , JungelAet al. MicroRNA-29, a key regulator of collagen expression in systemic sclerosis . Arthritis Rheum.62 ( 6 ), 1733 – 1743 ( 2010 ).
  • Kurowska-Stolarska M , AliverniniS , BallantineLEet al. MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis . Proc. Natl Acad. Sci. USA108 ( 27 ), 11193 – 11198 ( 2011 ).

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