Advanced search
Publication Cover
Epigenomics Volume 9, 2017 - Issue 6
Submit an article Journal homepage
3,202
Views
0
CrossRef citations to date
0
Altmetric
Editorial

Epigenetics and Noncommunicable Diseases

Gemma C Sharp1 MRC Integrative Epidemiology Unit, School of Oral & Dental Sciences, University of Bristol, Oakfield House, Bristol, BS8 2BN, UKCorrespondence[email protected]
&
Caroline L Relton2 MRC Integrative Epidemiology Unit, School of Social & Community Medicine, University of Bristol, Oakfield House, Bristol, BS8 2BN, UK
Pages 789-791 | Received 24 Mar 2017, Accepted 12 Apr 2017, Published online: 19 May 2017

References

  • WHO . WHO Global Status Report on Noncommunicable Diseases 2014 . World Health Organisation , Geneva, Switzerland , 1 – 51 ( 2014 ).
  • Bogdarina I , WelhamS , KingPJ , BurnsSP , ClarkAJL . Epigenetic modification of the renin-angiotensin system in the fetal programming of hypertension . Circ. Res.100 ( 4 ), 520 – 526 ( 2007 ).
  • Baylin SB , JonesPA . A decade of exploring the cancer epigenome – biological and translational implications . Nat. Rev. Cancer11 ( 10 ), 726 – 734 ( 2011 ).
  • DeVries A , WlasiukG , MillerSJet al. Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers . J. Allergy Clin. Immunol. doi:10.1016/j.jaci.2016.10.041 ( 2016 ) ( Epub ahead of print ).
  • Wahl S , DrongA , LehneBet al. Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity . Nature.541 ( 7635 ), 81 – 86 ( 2016 ).
  • Elliott HR , ShihabHA , LockettGAet al. The role of DNA methylation in Type 2 diabetes aetiology – using genotype as a causal anchor . Diabetes doi:10.2337/db16-0874 ( 2017 ) ( Epub ahead of print ).
  • Birney E , SmithGD , GreallyJM . Epigenome-wide association studies and the interpretation of disease-omics . PLoS Genet.12 ( 6 ), e1006105 ( 2016 ).
  • Richmond RC , Al-AminA , SmithGD , ReltonCL . Approaches for drawing causal inferences from epidemiological birth cohorts: a review . Early Hum. Dev.90 ( 11 ), 769 – 80 ( 2014 ).
  • Murray R , BryantJ , TitcombePet al. DNA methylation at birth within the promoter of ANRIL predicts markers of cardiovascular risk at 9 years . Clin. Epigenetics8 ( 1 ), 90 ( 2016 ).
  • Joubert BR , FelixJF , YousefiPet al. DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis . Am. J. Hum. Genet.98 ( 4 ), 680 – 696 ( 2016 ).
  • Brion M-JA , LawlorDA , MatijasevichAet al. What are the causal effects of breastfeeding on IQ, obesity and blood pressure? Evidence from comparing high-income with middle-income cohorts . Int. J. Epidemiol.40 ( 3 ), 670 – 680 ( 2011 ).
  • Castillo-Fernandez JE , SpectorTD , BellJT . Epigenetics of discordant monozygotic twins: implications for disease . Genome Med.6 ( 7 ), 60 ( 2014 ).
  • Davies MN , KrauseL , BellJTet al. Hypermethylation in the ZBTB20 gene is associated with major depressive disorder . Genome Biol.15 ( 4 ), R56 ( 2014 ).
  • Richmond RC , SharpGC , WardMEet al. DNA methylation and BMI: investigating identified methylation sites at HIF3A in a causal framework . Diabetes65 ( 5 ), 1231 – 1244 ( 2016 ).
  • Sharp GC , LawlorDA , RichmondRCet al. Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the avon longitudinal study of parents and children . Int. J. Epidemiol.44 ( 4 ), 1288 – 1304 ( 2015 ).
  • Davey Smith G , HemaniG . Mendelian randomization: genetic anchors for causal inference in epidemiological studies . Hum. Mol. Genet.23 ( R1 ), R89 – R98 ( 2014 ).
  • Relton CL , Davey SmithG . Two-step epigenetic mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease . Int. J. Epidemiol.41 ( 1 ), 161 – 76 ( 2012 ).
  • Relton CL , Davey SmithG . Mendelian randomization: applications and limitations in epigenetic studies . Epigenomics7 ( 8 ), 1239 – 1243 ( 2015 ).
  • Mendelson MM , MarioniRE , JoehanesRet al. Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a mendelian randomization approach . PLOS Med.14 ( 1 ), e1002215 ( 2017 ).
  • Relton CL , HartwigFP , Davey SmithG . From stem cells to the law courts: DNA methylation, the forensic epigenome and the possibility of a biosocial archive . Int. J. Epidemiol.44 ( 4 ), 1083 – 1093 ( 2015 ).
  • Liu C , MarioniRE , HedmanÅKet al. A DNA methylation biomarker of alcohol consumption . Mol. Psychiatry doi:10.1038/mp.2016.192 ( 2016 ) ( Epub ahead of print ).
  • Reese SE , ZhaoS , WuMCet al. DNA methylation score as a biomarker in newborns for sustained maternal smoking during pregnancy . Environ. Health Perspect.125 ( 4 ), 760 – 766 ( 2016 ).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.