157
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Adipose tissue DNA methylome changes in development of new-onset diabetes after kidney transplantation

, , , , , , , & show all
Pages 1423-1435 | Received 03 Apr 2017, Accepted 23 Jun 2017, Published online: 02 Oct 2017

References

  • Cosio FG , PesaventoTE , OseiK , HenryML , FergusonRM . Post-transplant diabetes mellitus: increasing incidence in renal allograft recipients transplanted in recent years . Kidney Int.59 ( 2 ), 732 – 737 ( 2001 ).
  • Dolzhenko E , SmithAD . Using beta-binomial regression for high-precision differential methylation analysis in multifactor whole-genome bisulfite sequencing experiments . BMC Bioinformat.15215 ( 2014 ).
  • Goldsmith D , PietrangeliCE . The metabolic syndrome following kidney transplantation . Kidney Int. Suppl.118 , S8 – S14 ( 2010 ).
  • Chakkera HA , KnowlerWC , DevarapalliYet al. Relationship between inpatient hyperglycemia and insulin treatment after kidney transplantation and future new onset diabetes mellitus . Clin. J. Am. Soc. Nephrol.5 ( 9 ), 1669 – 1675 ( 2010 ).
  • Cosio FG , KudvaY , Van Der VeldeMet al. New onset hyperglycemia and diabetes are associated with increased cardiovascular risk after kidney transplantation . Kidney Int.67 ( 6 ), 2415 – 2421 ( 2005 ).
  • Sharif A , BaboolalK . Complications associated with new-onset diabetes after kidney transplantation . Nat. Rev. Nephrol.8 ( 1 ), 34 – 42 ( 2012 ).
  • Wauters RP , CosioFG , Suarez FernandezML , KudvaY , ShahP , TorresVE . Cardiovascular consequences of new-onset hyperglycemia after kidney transplantation . Transplantation94 ( 4 ), 377 – 382 ( 2012 ).
  • Soleimanpour SA , CrutchlowMF , FerrariAMet al. Calcineurin signaling regulates human islet {beta}-cell survival . J. Biol. Chem.285 ( 51 ), 40050 – 40059 ( 2010 ).
  • Chakkera HA , KudvaY , KaplanB . Calcineurin inhibitors: pharmacologic mechanisms impacting both insulin resistance and insulin secretion leading to glucose dysregulation and diabetes mellitus . Clin. Pharmacol. Ther.101 ( 1 ), 114 – 120 ( 2017 ).
  • Defronzo RA , AlvestrandA , SmithD , HendlerR , HendlerE , WahrenJ . Insulin resistance in uremia . J. Clin. Invest.67 ( 2 ), 563 – 568 ( 1981 ).
  • Kobayashi S , MaesatoK , MoriyaH , OhtakeT , IkedaT . Insulin resistance in patients with chronic kidney disease . Am. J. Kidney Dis.45 ( 2 ), 275 – 280 ( 2005 ).
  • Lorenzo M , Fernandez-VeledoS , Vila-BedmarR , Garcia-GuerraL , De AlvaroC , Nieto-VazquezI . Insulin resistance induced by tumor necrosis factor-alpha in myocytes and brown adipocytes . J. Anim. Sci.86 ( 14 Suppl. ), E94 – E104 ( 2008 ).
  • Manolescu B , StoianI , AtanasiuV , BusuC , LupescuO . Review article: the role of adipose tissue in uraemia-related insulin resistance . Nephrol. (Carlton)13 ( 7 ), 622 – 628 ( 2008 ).
  • D’apolito M , DuX , ZongHet al. Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure . J. Clin. Invest.120 ( 1 ), 203 – 213 ( 2010 ).
  • Drong AW , LindgrenCM , MccarthyMI . The genetic and epigenetic basis of Type 2 diabetes and obesity . Clin. Pharmacol. Ther.92 ( 6 ), 707 – 715 ( 2012 ).
  • Gilbert ER , LiuD . Epigenetics: the missing link to understanding beta-cell dysfunction in the pathogenesis of Type 2 diabetes . Epigenetics7 ( 8 ), 841 – 852 ( 2012 ).
  • Nadler ST , StoehrJP , SchuelerKL , TanimotoG , YandellBS , AttieAD . The expression of adipogenic genes is decreased in obesity and diabetes mellitus . Proc. Natl Acad. Sci. USA97 ( 21 ), 11371 – 11376 ( 2000 ).
  • Yokomori N , TawataM , OnayaT . DNA demethylation during the differentiation of 3T3-L1 cells affects the expression of the mouse GLUT4 gene . Diabetes48 ( 4 ), 685 – 690 ( 1999 ).
  • ADA . Introduction: the American Diabetes Association’s (ADA) evidence-based practice guidelines, standards, and related recommendations and documents for diabetes care . Diabetes Care35 ( Suppl. 1 ), S1 – S2 ( 2012 ).
  • Sun Z , BahetiS , MiddhaSet al. SAAP-RRBS: streamlined analysis and annotation pipeline for reduced representation bisulfite sequencing . Bioinformatics28 ( 16 ), 2180 – 2181 ( 2012 ).
  • Xi Y , LiW . BSMAP: whole genome bisulfite sequence MAPping program . BMC Bioinform.10 , 232 ( 2009 ).
  • Li H , HandsakerB , WysokerAet al. The sequence alignment/map format and SAMtools . Bioinformatics25 ( 16 ), 2078 – 2079 ( 2009 ).
  • Qiagen Bioinformatics . http://www.ingenuity.com/
  • Liu Y , SiegmundKD , LairdPW , BermanBP . Bis-SNP: combined DNA methylation and SNP calling for Bisulfite-seq data . Genome Biol.13 ( 7 ), R61 ( 2012 ).
  • Nilsson E , JanssonPA , PerfilyevAet al. Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with Type 2 diabetes . Diabetes63 ( 9 ), 2962 – 2976 ( 2014 ).
  • Bani D , PiniA , YueSK . Relaxin, insulin and diabetes: an intriguing connection . Curr. Diabetes Rev.8 ( 5 ), 329 – 335 ( 2012 ).
  • Halls ML , BathgateRA , SuttonSW , DschietzigTB , SummersRJ . International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1–4, the receptors for relaxin family peptides . Pharmacol. Rev.67 ( 2 ), 389 – 440 ( 2015 ).
  • Liu Z , StanojevicV , AvadhaniS , YanoT , HabenerJF . Stromal cell-derived factor-1 (SDF-1)/chemokine (C-X-C motif) receptor 4 (CXCR4) axis activation induces intra-islet glucagon-like peptide-1 (GLP-1) production and enhances beta cell survival . Diabetologia54 ( 8 ), 2067 – 2076 ( 2011 ).
  • Vidakovic M , GrdovicN , DinicS , MihailovicM , UskokovicA , Arambasic JovanovicJ . the importance of the CXCL12/CXCR4 axis in therapeutic approaches to diabetes mellitus attenuation . Front. Immunol.6403 ( 2015 ).
  • Bonegio R , SusztakK . Notch signaling in diabetic nephropathy . Exp. Cell Res.318 ( 9 ), 986 – 992 ( 2012 ).
  • Kobashi C , AsamizuS , IshikiMet al. Inhibitory effect of IL-8 on insulin action in human adipocytes via MAP kinase pathway . J. Inflamm. (Lond.)625 ( 2009 ).
  • Basile KJ , JohnsonME , XiaQ , GrantSFA . Genetic susceptibility to Type 2 diabetes and obesity: follow-up of findings from genome-wide association studies . Int. J. Endocrinol. 201413 ( 2014 ).
  • Boyle AP , HongEL , HariharanMet al. Annotation of functional variation in personal genomes using RegulomeDB . Genome Res.22 ( 9 ), 1790 – 1797 ( 2012 ).
  • Ward LD , KellisM . HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants . Nucleic Acids Res.40 ( Database issue ), D930 – D934 ( 2012 ).
  • Eicher JD , LandowskiC , StackhouseBet al. GRASP v2.0: an update on the genome-wide repository of associations between SNPs and phenotypes . Nucleic Acids Res.43 ( Database issue ), D799 – D804 ( 2015 ).
  • Palepu S , PrasadGV . New-onset diabetes mellitus after kidney transplantation: current status and future directions . World J. Diabetes6 ( 3 ), 445 – 455 ( 2015 ).
  • Yamamoto H , ShimokawaH , HagaTet al. The expression of relaxin-3 in adipose tissue and its effects on adipogenesis . Protein Pept. Lett.21 ( 6 ), 517 – 522 ( 2014 ).
  • Pawlina W , LarkinLH , OgilvieS , FrostSC . Human relaxin inhibits division but not differentiation of 3T3-L1 cells . Mol. Cell Endocrinol.72 ( 1 ), 55 – 61 ( 1990 ).
  • Olefsky JM , SaekowM , KrocRL . Potentiation of insulin binding and insulin action by purified porcine relaxin . Ann. NY Acad. Sci.380200 – 216 ( 1982 ).
  • Jarrett JCN , BallejoG , SaleemTH , TsibrisJC , SpellacyWN . The effect of prolactin and relaxin on insulin binding by adipocytes from pregnant women . Am. J. Obstet. Gynecol.149 ( 3 ), 250 – 255 ( 1984 ).
  • Kim D , KimJ , YoonJHet al. CXCL12 secreted from adipose tissue recruits macrophages and induces insulin resistance in mice . Diabetologia57 ( 7 ), 1456 – 1465 ( 2014 ).
  • Cho HH , KyoungKM , SeoMJ , KimYJ , BaeYC , JungJS . Overexpression of CXCR4 increases migration and proliferation of human adipose tissue stromal cells . Stem Cells Dev.15 ( 6 ), 853 – 864 ( 2006 ).
  • Bi P , ShanT , LiuWet al. Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity . Nat. Med.20 ( 8 ), 911 – 918 ( 2014 ).
  • Xu H , ZhuJ , SmithSet al. Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization . Nat. Immunol.13 ( 7 ), 642 – 650 ( 2012 ).
  • Chartoumpekis DV , PalliyaguruDL , WakabayashiNet al. Notch intracellular domain overexpression in adipocytes confers lipodystrophy in mice . Mol. Metab.4 ( 7 ), 543 – 550 ( 2015 ).
  • Mccaughan JA , McknightAJ , MaxwellAP . Genetics of new-onset diabetes after transplantation . J. Am. Soc. Nephrol.25 ( 5 ), 1037 – 1049 ( 2014 ).
  • Mccaughan J , McknightA , MaxwellA . New onset diabetes after transplantation: unravelling the pathophysiological process . Lancet383 ( S73 ), ( 1037 – 1049 ( 2014 ).
  • Sun Z , CunninghamJ , SlagerS , KocherJP . Base resolution methylome profiling: considerations in platform selection, data preprocessing and analysis . Epigenomics7 ( 5 ), 813 – 828 ( 2015 ).
  • Zhang Y , BahetiS , SunZ . Statistical method evaluation for differentially methylated CpGs in base resolution next-generation DNA sequencing data . Brief Bioinform. doi:10.1093/bib/bbw133 ( 2016 ) ( Epub ahead of print ).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.