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Research Article

Intracellular African Swine Fever Virus DNA Remains Unmethylated in Infected Vero Cells

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Pages 289-299 | Received 11 Oct 2017, Accepted 05 Dec 2017, Published online: 12 Jan 2018

References

  • Doerfler W . DNA methylation and gene activity . Ann. Rev. Biochem.52 , 93 – 124 ( 1983 ).
  • Doerfler W . Epigenetic consequences of foreign DNA integration: global alterations of methylation and transcription patterns in recipient genomes . Rev. Med. Virol.21 , 336 – 346 ( 2011 ).
  • Sutter D , WestphalM , DoerflerW . Patterns of integration of viral DNA sequences in the genomes of adenovirus type 12-transformed hamster cells . Cell14 , 569 – 585 ( 1978 ).
  • Sutter D , DoerflerW . Methylation of integrated adenovirus type 12 DNA sequences in transformed cells is inversely correlated with viral gene expression . Proc. Natl Acad. Sci. USA77 , 253 – 256 ( 1980 ).
  • Vardimon L , NeumannR , KuhlmannI , SutterD , DoerflerW . DNA methylation and viral gene expression in adenovirus-transformed and -infected cells . Nucleic Acids Res.8 , 2461 – 2473 ( 1980 ).
  • Wienhues U , DoerflerW . Lack of evidence for methylation of parental and newly synthesized adenovirus type 2 DNA in productive infections . J. Virol.56 , 320 – 324 ( 1985 ).
  • Kämmer C , DoerflerW . Genomic sequencing reveals absence of DNA methylation in the major late promoter of adenovirus type 2 DNA in the virion and in productively infected cells . FEBS Lett.362 , 301 – 305 ( 1995 ).
  • Hochstein N , MuiznieksI , MangelL , BrondkeH , DoerflerW . Epigenetic status of an adenovirus type 12 transgenome upon long-term cultivation in hamster cells . J. Virol.81 , 5349 – 5361 ( 2007 ).
  • Kalantari M , OsannK , Calleja-MaciasIEet al. Methylation of human papillomavirus 16, 18, 31 and 45 L2 and L1 genes and the cellular DAPK gene: considerations for use as biomarkers of the progression of cervical neoplasia . Virology448 , 314 – 321 ( 2014 ).
  • Falk KI , SzekelyL , AlemanA , ErnbergI . Specific methylation patterns in two control regions of Epstein–Barr virus latency: the LMP-1-coding upstream regulatory region and an origin of DNA replication (oriP) . J. Virol.72 , 2969 – 2974 ( 1998 ).
  • Birdwell CE , QueenKJ , KilgorePCSRet al. Genome-wide DNA methylation as an epigenetic consequence of Epstein–Barr virus infection of immortalized keratinocytes . J. Virol.88 , 11442 – 11458 ( 2014 ).
  • Scott RS . Epstein–Barr virus: a master epigenetic manipulator . Curr. Opin. Virol.26 , 74 – 80 ( 2017 ).
  • Karlin S , DoerflerW , CardonLR . Why is CpG suppressed in the genomes of virtually all small eukaryotic viruses but not in those of large eukaryotic viruses?J. Virol.68 , 2889 – 2897 ( 1994 ).
  • Darst RP , HaeckerI , PardoCE , RenneR , KladdeMP . Epigenetic diversity of Kaposi’s sarcoma-associated herpesvirus . Nucl. Acids Res.41 , 2993 – 3009 ( 2013 ).
  • Zakaryan H , RevillaY . African swine fever virus: current state and future perspectives in vaccine and antiviral research . Vet. Microbiol.185 , 15 – 19 ( 2016 ).
  • Rodriguez JM , MorenoLT , AlejoA , LacastaA , RodriguezF , SalasML . Genome sequence of African swine fever virus BA71, the virulent parental strain of the nonpathogenic and tissue-culture adapted BA71V . PLoS ONE10 ( 11 ), e0142889 ( 2015 ).
  • Yáñez RJ , RodríguezJM , NogalMLet al. Analysis of the complete nucleotide sequence of African swine fever virus . Virology208 , 249 – 278 ( 1995 ).
  • Rodríguez JM , SalasML . African swine fever virus transcription . Virus. Res.173 , 15 – 28 ( 2013 ).
  • Sánchez EG , QuintasA , NogalM , CastellóA , RevillaY . African swine fever virus controls the host transcription and cellular machinery of protein synthesis . Virus Res.173 , 58 – 75 ( 2013 ).
  • Simões M , RinoJ , PinheiroI , MartinsC , FerreiraF . Alterations of nuclear architecture and epigenetic signatures during African swine fever virus infection . Viruses7 , 4978 – 4996 ( 2015 ).
  • EMBOSS Cpgplot . www.ebi.ac.uk/Tools/seqstats/emboss_cpgplot/ .
  • Zhong C , HouZ , HuangJ , XieQ , ZhongY . Mutations and CpG islands among hepatitis B virus genotypes in Europe . BMC Bioinformatics16 , 38 ( 2015 ).
  • Carrascosa AL , BustosMJ , de LeónP . Methods for growing and titrating African swine fever virus: field and laboratory samples . Curr. Protoc. Cell Biol. Chapter 26(Unit 26) , 14 ( 2011 ).
  • Bastos ADS , PenrithML , CrucièreCet al. Genotyping field strains of African swine fever virus by partial p72 gene characterization . Arch. Virol.148 , 693 – 706 ( 2003 ).
  • Frommer M , McDonaldLE , MillarDSet al. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands . Proc. Natl Acad. Sci. USA89 , 1827 – 1831 ( 1992 ).
  • Clark SJ , HarrisonJ , PaulCL , FrommerM . High sensitivity mapping of methylated cytosines . Nucl. Acids Res.22 , 2990 – 2999 ( 1994 ).
  • Naumann A , HochsteinN , WeberS , FanningE , DoerflerW . A distinct DNA methylation boundary in the 5′-upstream sequence of the FMR1 promoter binds nuclear proteins and is lost in fragile X syndrome . Am. J. Hum. Genet.85 , 606 – 616 ( 2009 ).
  • NCBI GenBank . African swine fever virus strain BA71V, complete genome . www.ncbi.nlm.nih.gov/nuccore/NC_001659.2 .
  • Rojo G , García-BeatoR , ViñuelaE , SalasM-L , SalasJ . Replication of African swine fever virus DNA in infected cells . Virology257 , 524 – 536 ( 1999 ).
  • Dixon LK , ChapmanDA , NethertonCL , UptonC . African swine fever virus replication and genomics . Virus Res.173 , 3 – 14 ( 2013 ).
  • Almendral JM , AlmazánF , BlascoR , ViñuelaE . Multigene families in African swine fever virus: family 110 . J. Virol.64 , 2064 – 2072 ( 1990 ).
  • Yáñez RJ , RodríguezJM , BoursnellM , RodríguezJF , ViñuelaE . Two putative African swine fever virus helicases similar to yeast ‘DEAH’ pre-mRNA processing proteins and vaccinia virus ATPases D11L and D6R . Gene134 , 161 – 174 ( 1993a ).
  • Prados FJ , ViñuelaE , AlcamíA . Sequence and characterization of the major early phosphoprotein p32 of African swine fever virus . J. Virol.67 , 2475 – 2485 ( 1993 ).
  • Rodriguez JM , SalasML , ViñuelaE . Genes homologous to ubiquitin conjugating proteins and eukaryotic transcription factor SII in African swine fever virus . Virology186 , 40 – 52 ( 1992 ).
  • Lu Z , KutishGF , SussmanMD , RockDL . An African swine fever virus gene with a similarity to eukaryotic RNA polymerase subunit 6 . Nucl. Acids Res.21 , 2940 ( 1993 ).
  • Dixon LK , TwiggSR , BaylisSAet al. Nucleotide sequence of a 55 kbp region from the right end of the genome of a pathogenic African swine fever virus isolate (Malawi LIL20/1) . J. Gen. Virol.75 , 1655 – 1684 ( 1994 ).
  • García-Beato R , FreijeJM , López-OtínC , BlascoR , ViñuelaE , SalasML . A gene homologous to topoisomerase II in African swine fever virus . Virology188 , 938 – 947 ( 1992 ).
  • Yáñez RJ , BoursnellM , NogalML , YusteL , ViñuelaE . African swine fever virus encodes two genes which share significant homology with the two largest subunits of DNA-dependent RNA polymerases . Nucl. Acids Res.21 , 2423 – 2427 ( 1993b ).
  • Baylis SA , TwiggSR , VydelingumS , DixonLK , SmithGL . Three African swine fever virus genes encoding proteins with homology to putative helicases of vaccinia virus . J. Gen. Virol.74 , 1969 – 1974 ( 1993 ).
  • Yáñez RJ , ViñuelaE . African swine fever virus encodes a DNA ligase . Virology193 , 531 – 536 ( 1993c ).
  • Hoeben RC , UilTG . Adenovirus DNA replication . Cold Spring Harb. Perspect. Biol.5 ( 3 ), a013003 ( 2013 ).
  • Deuring R , KlotzG , DoerflerW . An unusual symmetric recombinant between adenovirus type 12 DNA and human cell DNA . Proc. Natl Acad. Sci. USA78 , 3142 – 3146 ( 1981 ).
  • Bednarik DP , CookJA , PithaPM . Inactivation of the HIV LTR by DNA CpG methylation: evidence for a role in latency . EMBO J.9 , 1157 – 1164 ( 1990 ).
  • Blazkova J , MurrayD , JustementJSet al. Paucity of HIV DNA methylation in latently infected, resting CD4+ T cells from infected individuals receiving antiretroviral therapy . J. Virol.86 , 5390 – 5392 ( 2012 ).
  • Weber S , WeiserB , BurgerHet al. Epigenetic analysis of HIV-1 proviral genomes from infected individuals: predominance of unmethylated CpG’s . Virology449 , 181 – 189 ( 2014 ).
  • Willis DB , GranoffA . Frog virus 3 DNA is heavily methylated at CpG sequences . Virology107 , 250 – 257 ( 1980 ).
  • Munnes M , SchetterC , HölkerI , DoerflerW . A fully 5′-CG-3′ but not a 5′-CCGG-3′ methylated late frog virus 3 promoter retains activity . J. Virol.69 , 2240 – 2247 ( 1995 ).

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