74
Views
0
CrossRef citations to date
0
Altmetric
Research Article

The Effect of Inflammation-Related Lifestyle Exposures and Interactions with Gene Variants on Long Interspersed Nuclear Element-1 DNA Methylation

, &
Pages 785-796 | Received 12 Dec 2017, Accepted 20 Feb 2018, Published online: 11 Jun 2018

References

  • Esteller M . Epigenetics in cancer . N. Engl. J. Med. 2008 ( 358 ), 1148 – 1159 ( 2008 ).
  • De Koning AJ , GuW , CastoeTA , BatzerMA , PollockDD . Repetitive elements may comprise over two-thirds of the human genome . PLoS Genet.7 ( 12 ), e1002384 ( 2011 ).
  • Rollins RA , HaghighiF , EdwardsJRet al. Large-scale structure of genomic methylation patterns . Genome Res.16 ( 2 ), 157 – 163 ( 2006 ).
  • Miousse IR , ChalbotM-CG , LumenA , FergusonA , KavourasIG , KoturbashI . Response of transposable elements to environmental stressors . Mutat. Res. Rev. Mutat. Res.765 , 19 – 39 ( 2015 ).
  • Kemp JR , LongworthMS . Crossing the LINE toward genomic instability: LINE-1 retrotransposition in cancer . Front. Chem. ( 2015 ). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679865/ .
  • Deroo LA , BolickSC , XuZet al. Global DNA methylation and one-carbon metabolism gene polymorphisms and the risk of breast cancer in the Sister Study . Carcinogenesis35 ( 2 ), 333 – 338 ( 2013 ).
  • Lam K , PanK , LinnekampJF , MedemaJP , KandimallaR . DNA methylation based biomarkers in colorectal cancer: a systematic review . Biochim. Biophys. Acta1866 ( 1 ), 106 – 120 ( 2016 ).
  • Joyce BT , GaoT , ZhengYet al. Prospective changes in global DNA methylation and cancer incidence and mortality . Br. J. Cancer115 ( 4 ), 465 – 472 ( 2016 ).
  • Zhu Z-Z , SparrowD , HouLet al. Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence, and mortality in elderly individuals: the Normative Aging Study . Cancer Causes Control22 ( 3 ), 437 – 447 ( 2011 ).
  • Cash HL , TaoL , YuanJMet al. LINE-1 hypomethylation is associated with bladder cancer risk among nonsmoking Chinese . Int. J. Cancer130 ( 5 ), 1151 – 1159 ( 2012 ).
  • Piyathilake CJ , MacalusoM , AlvarezRDet al. A higher degree of LINE-1 methylation in peripheral blood mononuclear cells, a one-carbon nutrient related epigenetic alteration, is associated with a lower risk of developing cervical intraepithelial neoplasia . Nutrition27 ( 5 ), 513 – 519 ( 2011 ).
  • Senthong A , KitkumthornN , RattanatanyongP , KhemapechN , TriratanachartS , MutiranguraA . Differences in LINE-1 methylation between endometriotic ovarian cyst and endometriosis-associated ovarian cancer . Int. J. Gynecol. Cancer24 ( 1 ), 36 – 42 ( 2014 ).
  • Kawano H , SaekiH , KitaoHet al. Chromosomal instability associated with global DNA hypomethylation is associated with the initiation and progression of esophageal squamous cell carcinoma . Ann. Surg. Oncol.21 ( 4 ), 696 – 702 ( 2014 ).
  • Gao Y , BaccarelliA , ShuXet al. Blood leukocyte Alu and LINE-1 methylation and gastric cancer risk in the Shanghai Women’s Health Study . Br. J. Cancer106 ( 3 ), 585 – 591 ( 2012 ).
  • Barchitta M , QuattrocchiA , MaugeriA , VinciguerraM , AgodiA . LINE-1 hypomethylation in blood and tissue samples as an epigenetic marker for cancer risk: a systematic review and meta-analysis . PLoS ONE9 ( 10 ), e109478 ( 2014 ).
  • Woo HD , KimJ . Global DNA hypomethylation in peripheral blood leukocytes as a biomarker for cancer risk: a meta-analysis . PLoS ONE7 ( 4 ), e34615 ( 2012 ).
  • Muka T , KoromaniF , PortillaEet al. The role of epigenetic modifications in cardiovascular disease: a systematic review . Int. J. Cardiol.212 , 174 – 183 ( 2016 ).
  • Coussens LM , WerbZ . Inflammation and cancer . Nature420 ( 6917 ), 860 – 867 ( 2002 ).
  • Gasche JA , HoffmannJ , BolandCR , GoelA . Interleukin-6 promotes tumorigenesis by altering DNA methylation in oral cancer cells . Int. J. Cancer129 ( 5 ), 1053 – 1063 ( 2011 ).
  • O’hagan HM , WangW , SenSet al. Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands . Cancer Cell20 ( 5 ), 606 – 619 ( 2011 ).
  • Oberdoerffer P , MichanS , McVayMet al. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging . Cell135 ( 5 ), 907 – 918 ( 2008 ).
  • Horsburgh S , Robson-AnsleyP , AdamsR , SmithC . Exercise and inflammation-related epigenetic modifications: focus on DNA methylation . Exerc. Immunol. Rev.21 , 26 – 41 ( 2015 ).
  • Yiannakopoulou E . Targeting epigenetic mechanisms and microRNAs by aspirin and other non steroidal anti-inflammatory agents-implications for cancer treatment and chemoprevention . Cell. Oncol.37 ( 3 ), 167 – 178 ( 2014 ).
  • Robson-Ansley P , SainiA , TomsCet al. Dynamic changes in DNA methylation status in peripheral blood mononuclear cells following an acute bout of exercise: potential impact of exercise-induced elevations in interleukin-6 concentration . J. Biol. Regul. Homeost. Agents28 , 407 – 417 ( 2014 ).
  • Da Silva IRV , De AraujoCLP , DornelesGPet al. Exercise-modulated epigenetic markers and inflammatory response in COPD individuals: a pilot study . Respir. Physiol. Neurobiol.242 , 89 – 95 ( 2017 ).
  • Fernández-Sánchez A , Madrigal-SantillánE , BautistaMet al. Inflammation, oxidative stress, and obesity . Int. J. Mol. Sci.12 ( 5 ), 3117 – 3132 ( 2011 ).
  • White AJ , SandlerDP , BolickSC , XuZ , TaylorJA , DerooLA . Recreational and household physical activity at different time points and DNA global methylation . Eur. J. Cancer49 ( 9 ), 2199 – 2206 ( 2013 ).
  • Duggan C , XiaoL , TerryMB , MctiernanA . No effect of weight loss on LINE-1 methylation levels in peripheral blood leukocytes from postmenopausal overweight women . Obesity22 ( 9 ), 2091 – 2096 ( 2014 ).
  • King-Himmelreich TS , SchrammS , WoltersMCet al. The impact of endurance exercise on global and AMPK gene-specific DNA methylation . Biochem. Biophys. Res. Comm.474 ( 2 ), 284 – 290 ( 2016 ).
  • Delgado-Cruzata L , ZhangW , McDonaldJAet al. Dietary modifications, weight loss, and changes in metabolic markers affect global DNA methylation in Hispanic, African American, and Afro-Caribbean breast cancer survivors . J. Nutr.145 ( 4 ), 783 – 790 ( 2015 ).
  • Zhang FF , CardarelliR , CarrollJet al. Physical activity and global genomic DNA methylation in a cancer-free population . Epigenetics6 ( 3 ), 293 – 299 ( 2011 ).
  • Morabia A , ZhangFF , KappilMAet al. Biologic and epigenetic impact of commuting to work by car or using public transportation: a case–control study . Prev. Med.54 ( 3 ), 229 – 233 ( 2012 ).
  • Perng W , VillamorE , ShroffMet al. Dietary intake, plasma homocysteine, and repetitive element DNA methylation in the Multi-Ethnic Study of Atherosclerosis (MESA) . Nutr. Metab. Cardiovasc. Dis.24 ( 6 ), 614 – 622 ( 2014 ).
  • Van Dijk SJ , MolloyP , VarinliHet al. Epigenetics and human obesity . Int. J. Obesity39 ( 1 ), 85 – 97 ( 2015 ).
  • Sharp L , LittleJ . Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review . Am. J. Epidemiol.159 ( 5 ), 423 – 443 ( 2004 ).
  • King WD , AshburyJE , TaylorSAet al. A cross-sectional study of global DNA methylation and risk of colorectal adenoma . BMC Cancer14 ( 1 ), 488 ( 2014 ).
  • Tse MY , AshburyJE , ZwingermanN , KingWD , TaylorSA , PangSC . A refined, rapid and reproducible high resolution melt (HRM)-based method suitable for quantification of global LINE-1 repetitive element methylation . BMC Res. Notes4 ( 1 ), 565 ( 2011 ).
  • Ehrich M , BöckerS , Van Den BoomD . Multiplexed discovery of sequence polymorphisms using base-specific cleavage and MALDI-TOF MS . Nucleic Acids Res.33 ( 4 ), e38 ( 2005 ).
  • Lee KW , PausovaZ . Cigarette smoking and DNA methylation . Front. Genet. ( 2013 ). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713237/ .
  • Terry MB , Delgado-CruzataL , Vin-RavivN , WuHC , SantellaRM . DNA methylation in white blood cells: association with risk factors in epidemiologic studies . Epigenetics6 ( 7 ), 828 – 837 ( 2011 ).
  • Schernhammer ES , GiovannucciE , KawasakiT , RosnerB , FuchsC , OginoS . Dietary folate, alcohol, and B vitamins in relation to LINE-1 hypomethylation in colon cancer . Gut59 ( 6 ), 794 – 799 ( 2010 ).
  • Delgado-Cruzata L , WuH-C , LiaoY , SantellaRM , TerryMB . Differences in DNA methylation by extent of breast cancer family history in unaffected women . Epigenetics9 ( 2 ), 243 – 248 ( 2014 ).
  • Craig CL , MarshallAL , SjöströmMet al. International physical activity questionnaire: 12-country reliability and validity . Med. Sci. Sports Exerc.35 ( 8 ), 1381 – 1395 ( 2003 ).
  • Van Poppel MN , ChinapawMJ , MokkinkLB , Van MechelenW , TerweeCB . Physical activity questionnaires for adults . Sports Med.40 ( 7 ), 565 – 600 ( 2010 ).
  • Ainsworth BE , HaskellWL , WhittMCet al. Compendium of physical activities: an update of activity codes and MET intensities . Med. Sci. Sports Exerc.32 ( 9, Suppl. 1 ), S498 – S504 ( 2000 ).
  • BMI Classification . WHO , Geneva, Switzerland ( 2013 ).
  • Wilson LE , KimS , XuZ , HarlidS , SandlerDP , TaylorJA . Non-steroidal anti-inflammatory drug use and genomic DNA methylation in blood . PLoS ONE10 ( 9 ), e0138920 ( 2015 ).
  • 2015–2020 Dietary Guidelines for Americans (8th Edition) . US Department of Health and Human Services and US Department of Agriculture , Washington, DC, USA ( 2015 ).
  • Byers T , MarshallJ , FiedlerR , ZieleznyM , GrahamS . Assessing nutrient intake with an abbreviated dietary interview . Am. J. Epidemiol.122 ( 1 ), 41 – 50 ( 1985 ).
  • Foley DL , CraigJM , MorleyRet al. Prospects for epigenetic epidemiology . Am. J. Epidemiol.169 ( 4 ), 389 – 400 ( 2009 ).
  • Zhang FF , CardarelliR , CarrollJet al. Significant differences in global genomic DNA methylation by gender and race/ethnicity in peripheral blood . Epigenetics6 ( 5 ), 623 – 629 ( 2011 ).
  • Rothman KJ , GreenlandS , LashTL . Modern Epidemiology . Wolters Kluwer Health/Lippincott Williams & Wilkins , PA, USA ( 2008 ).
  • Zhu Z-Z , HouL , BollatiVet al. Predictors of global methylation levels in blood DNA of healthy subjects: a combined analysis . Int. J. Epidemiol.41 ( 1 ), 126 – 139 ( 2010 ).
  • Tajuddin SM , AmaralAF , FernándezAFet al. Genetic and non-genetic predictors of LINE-1 methylation in leukocyte DNA . Environ. Health Perspect.121 ( 6 ), 650 ( 2013 ).
  • Hsiung DT , MarsitCJ , HousemanEAet al. Global DNA methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma . Cancer Epidemiol. Biomarkers Prev.16 ( 1 ), 108 – 114 ( 2007 ).
  • Moore LE , PfeifferRM , PoscabloCet al. Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case–control study . Lancet Oncol.9 ( 4 ), 359 – 366 ( 2008 ).
  • Moore LD , LeT , FanG . DNA methylation and its basic function . Neuropsychopharmacology38 ( 1 ), 23 – 38 ( 2013 ).
  • Luttropp K , NordforsL , EkströmTJ , LindL . Physical activity is associated with decreased global DNA methylation in Swedish older individuals . Scand. J. Clin. Lab. Invest.73 ( 2 ), 184 – 185 ( 2013 ).
  • Gomes MV , ToffoliLV , ArrudaDWet al. Age-related changes in the global DNA methylation profile of leukocytes are linked to nutrition but are not associated with the MTHFR C677T genotype or to functional capacities . PLoS ONE7 ( 12 ), e52570 ( 2012 ).
  • Kok RM , SmithDE , BartoRet al. Global DNA methylation measured by liquid chromatography–tandem mass spectrometry: analytical technique, reference values and determinants in healthy subjects . Clin. Chem. Lab. Med.45 ( 7 ), 903 – 911 ( 2007 ).
  • Piyathilake CJ , BadigaS , AlvarezRD , PartridgeEE , JohanningGL . A lower degree of PBMC L1 methylation is associated with excess body weight and higher HOMA-IR in the presence of lower concentrations of plasma folate . PLoS ONE8 ( 1 ), e54544 ( 2013 ).
  • Serum and Red Blood Cell Folate Concentrations for Assessing Folate Status in Populations . WHO , Geneva, Switzerland ( 2015 ).
  • Tahara T , ShibataT , YamashitaHet al. Chronic nonsteroidal anti-inflammatory drug (NSAID) use suppresses multiple CpG islands hyper methylation (CIHM) of tumor suppressor genes in the human gastric mucosa . Cancer Sci.100 ( 7 ), 1192 – 1197 ( 2009 ).
  • Pan M-R , ChangH-C , ChuangL-Y , HungW-C . The nonsteroidal anti-inflammatory drug NS398 reactivates SPARC expression via promoter demethylation to attenuate invasiveness of lung cancer cells . Exp. Biol. Med.233 ( 4 ), 456 – 462 ( 2008 ).
  • Harris RE , Beebe-DonkJ , DossH , DossDB . Aspirin, ibuprofen, and other non-steroidal anti-inflammatory drugs in cancer prevention: a critical review of non-selective COX-2 blockade . Oncol. Rep.13 ( 4 ), 559 – 583 ( 2005 ).
  • Brasky TM , PotterJD , KristalARet al. Non-steroidal anti-inflammatory drugs and cancer incidence by sex in the VITamins And Lifestyle (VITAL) cohort . Cancer Causes Control23 ( 3 ), 431 – 444 ( 2012 ).
  • Franco R , SchoneveldO , GeorgakilasAG , PanayiotidisMI . Oxidative stress, DNA methylation and carcinogenesis . Cancer Lett.266 ( 1 ), 6 – 11 ( 2008 ).
  • Donkena KV , YoungCY , TindallDJ . Oxidative stress and DNA methylation in prostate cancer . Obstet. Gynecol. Int. ( 2010 ). https://www.hindawi.com/journals/ogi/2010/302051/ .
  • Huang SK , ScruggsAM , DonaghyJet al. Prostaglandin E2 increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expression . FASEB J.26 ( 9 ), 3703 – 3714 ( 2012 ).
  • Xia D , WangD , KimS-H , KatohH , DuboisRN . Prostaglandin E2 promotes intestinal tumor growth via DNA methylation . Nat. Med.18 ( 2 ), 224 – 226 ( 2012 ).
  • Weisenberger DJ , CampanM , LongTIet al. Analysis of repetitive element DNA methylation by MethyLight . Nucleic Acids Res.33 ( 21 ), 6823 – 6836 ( 2005 ).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.