DNA Methylation Profiling as a Tool for Testicular Germ Cell Tumors Subtyping

References

• Ferlay J , SoerjomataramI , DikshitRet al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012 . Int. J. Cancer136 ( 5 ), e359 – e386 ( 2015 ).
   PubMed Web of Science ®Google Scholar
• Trabert B , ChenJ , DevesaS , BrayF , McGlynnK . International patterns and trends in testicular cancer incidence, overall and by histologic subtype, 1973–2007 . Andrology3 ( 1 ), 4 – 12 ( 2015 ).
   PubMed Web of Science ®Google Scholar
• SEER Cancer Statistics Review, 1975–2013 . HowladerN , NooneA , KrapchoM ( Eds ). National Cancer Institute . http://seer.cancer.gov/csr/1975_2013
   Google Scholar
• Hanna NH , EinhornLH . Testicular cancer – discoveries and updates . N. Engl. J. Med.371 ( 21 ), 2005 – 2016 ( 2014 ).
   PubMed Web of Science ®Google Scholar
• Stevenson SM , LowranceWT . Epidemiology and diagnosis of testis cancer . Urol. Clin. North Am.42 ( 3 ), 269 – 275 ( 2015 ).
   PubMed Web of Science ®Google Scholar
• Oosterhuis JW , LooijengaLH . Testicular germ-cell tumours in a broader perspective . Nat. Rev. Cancer5 ( 3 ), 210 – 222 ( 2005 ).
   PubMed Web of Science ®Google Scholar
• Rajpert-De Meyts E , McGlynnKA , OkamotoK , JewettMA , BokemeyerC . Testicular germ cell tumours . Lancet387 ( 10029 ), 1762 – 1774 ( 2016 ).
   PubMed Web of Science ®Google Scholar
• Murray MJ , HuddartRA , ColemanN . The present and future of serum diagnostic tests for testicular germ cell tumours . Nat. Rev. Urol.13 ( 12 ), 715 – 725 ( 2016 ).
   PubMed Web of Science ®Google Scholar
• Kawakami T , OkamotoK , OgawaO , OkadaY . XIST unmethylated DNA fragments in male-derived plasma as a tumour marker for testicular cancer . Lancet363 ( 9402 ), 40 – 42 ( 2004 ).
   PubMed Web of Science ®Google Scholar
• Rijlaarsdam MA , TaxDM , GillisAJet al. Genome wide DNA methylation profiles provide clues to the origin and pathogenesis of germ cell tumors . PLoS ONE10 ( 4 ), e0122146 ( 2015 ).
   PubMed Web of Science ®Google Scholar
• Gillis AJ , RijlaarsdamMA , EiniRet al. Targeted serum miRNA (TSmiR) test for diagnosis and follow-up of (testicular) germ cell cancer patients: a proof of principle . Mol. Oncol.7 ( 6 ), 1083 – 1092 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Moch H , CubillaAL , HumphreyPA , ReuterVE , UlbrightTM . The 2016 WHO classification of tumours of the urinary system and male genital organs-part A: renal, penile, and testicular tumours . Eur. Urol.70 ( 1 ), 93 – 105 ( 2016 ).
   PubMed Web of Science ®Google Scholar
• WHO Classification of Tumours of the Urinary System and Male Genital Organs (4th Edition) . MochH , UlbrightT , ReuterV ( Eds ). IARC , Lyon, France ( 2016 ).
   Google Scholar
• Litchfield K , LevyM , HuddartRA , ShipleyJ , TurnbullC . The genomic landscape of testicular germ cell tumours: from susceptibility to treatment . Nat. Rev. Urol.13 ( 7 ), 409 – 419 ( 2016 ).
   PubMed Web of Science ®Google Scholar
• Costa AL , LoboJ , JerónimoC , HenriqueR . The epigenetics of testicular germ cell tumors: looking for novel disease biomarkers . Epigenomics9 ( 2 ), 155 – 169 ( 2017 ).
   PubMed Web of Science ®Google Scholar
• Spiller CM , GillisAJ , BurnetGet al. Cripto: expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors . Mol. Oncol.10 ( 4 ), 526 – 537 ( 2016 ).
   PubMed Web of Science ®Google Scholar
• Smiraglia DJ , SzymanskaJ , KraggerudSM , LotheRA , PeltomäkiP , PlassC . Distinct epigenetic phenotypes in seminomatous and nonseminomatous testicular germ cell tumors . Oncogene21 ( 24 ), 3909 ( 2002 ).
   PubMed Web of Science ®Google Scholar
• Koul S , HouldsworthJ , MansukhaniMMet al. Characteristic promoter hypermethylation signatures in male germ cell tumors . Mol. Cancer1 ( 1 ), 8 ( 2002 ).
   PubMedGoogle Scholar
• Smith-S⊘rensen B , LindG , SkotheimRet al. Frequent promoter hypermethylation of the O6-methylguanine-DNA methyltransferase (MGMT) gene in testicular cancer . Oncogene21 ( 57 ), 8878 ( 2002 ).
   PubMed Web of Science ®Google Scholar
• Honorio S , AgathanggelouA , WernertN , RotheM , MaherER , LatifF . Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours . Oncogene22 ( 3 ), 461 – 466 ( 2003 ).
   PubMed Web of Science ®Google Scholar
• Cottrell SE , LairdPW . Sensitive detection of DNA methylation . Ann. NY Acad. Sci.983 ( 1 ), 120 – 130 ( 2003 ).
   PubMedGoogle Scholar
• Eads CA , LordRV , WickramasingheKet al. Epigenetic patterns in the progression of esophageal adenocarcinoma . Cancer Res.61 ( 8 ), 3410 – 3418 ( 2001 ).
   PubMed Web of Science ®Google Scholar
• Ramalho-Carvalho J , PiresM , LisboaSet al. Altered expression of MGMT in high-grade gliomas results from the combined effect of epigenetic and genetic aberrations . PLoS ONE8 ( 3 ), e58206 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Lind G , SkotheimR , FragaM , AbelerV , EstellerM , LotheR . Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1) . J. Pathol.210 ( 4 ), 441 – 449 ( 2006 ).
   PubMed Web of Science ®Google Scholar
• Arya M , ShergillIS , WilliamsonM , GommersallL , AryaN , PatelHR . Basic principles of real-time quantitative PCR . Expert. Rev. Mol. Diagn.5 ( 2 ), 209 – 219 ( 2005 ).
   PubMed Web of Science ®Google Scholar
• Mead G , StenningS . The International Germ Cell Consensus Classification: a new prognostic factor-based staging classification for metastatic germ cell tumours . Clin. Oncol.9 ( 4 ), 207 – 209 ( 1997 ).
   Google Scholar
• Sharma P , DhillonJ , AgarwalG , Zargar-ShoshtariK , SextonWJ . Disparities in interpretation of primary testicular germ cell tumor pathology . Am. J. Clin. Pathol.144 ( 2 ), 289 – 294 ( 2015 ).
   PubMed Web of Science ®Google Scholar
• Murray MJ , ColemanN . Testicular cancer: a new generation of biomarkers for malignant germ cell tumours . Nat. Rev. Urol.9 ( 6 ), 298 – 300 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Brait M , MaldonadoL , BegumSet al. DNA methylation profiles delineate epigenetic heterogeneity in seminoma and non-seminoma . Br. J. Cancer106 ( 2 ), 414 – 423 ( 2012 ).
   PubMed Web of Science ®Google Scholar
• Netto GJ , NakaiY , NakayamaMet al. Global DNA hypomethylation in intratubular germ cell neoplasia and seminoma, but not in nonseminomatous male germ cell tumors . Mod. Pathol.21 ( 11 ), 1337 – 1344 ( 2008 ).
   PubMed Web of Science ®Google Scholar
• Hoque MO , TopalogluO , BegumSet al. Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects . J. Clin. Oncol.23 ( 27 ), 6569 – 6575 ( 2005 ).
   PubMed Web of Science ®Google Scholar
• Fackler MJ , McVeighM , MehrotraJet al. Quantitative multiplex methylation-specific PCR assay for the detection of promoter hypermethylation in multiple genes in breast cancer . Cancer Res.64 ( 13 ), 4442 – 4452 ( 2004 ).
   PubMed Web of Science ®Google Scholar
• Shames DS , MinnaJD , GazdarAF . Methods for detecting DNA methylation in tumors: from bench to bedside . Cancer Lett.251 ( 2 ), 187 – 198 ( 2007 ).
   PubMed Web of Science ®Google Scholar
• Rijlaarsdam MA , LooijengaLH . An oncofetal and developmental perspective on testicular germ cell cancer . Semin. Cancer Biol.29 , 59 – 74 ( 2014 ).
   PubMed Web of Science ®Google Scholar
• Cheng L , LyuB , RothLM . Perspectives on testicular germ cell neoplasms . Hum. Pathol.59 , 10 – 25 ( 2017 ).
   PubMed Web of Science ®Google Scholar
• Spiller CM , BowlesJ , KoopmanP . Nodal/Cripto signaling in fetal male germ cell development: implications for testicular germ cell tumors . Int. J. Dev. Biol.57 ( 2-3-4 ), 211 – 219 ( 2013 ).
   PubMed Web of Science ®Google Scholar
• Ross JH , RybickiL , KayR . Clinical behavior and a contemporary management algorithm for prepubertal testis tumors: a summary of the Prepubertal Testis Tumor Registry . J. Urol.168 ( 4 ), 1675 – 1679 ( 2002 ).
   PubMed Web of Science ®Google Scholar
• David S , AndrásF , EndreKet al. More cases of benign testicular teratomas are detected in adults than in children. a clinicopathological study of 543 testicular germ cell tumor cases . Pathol. Oncol. Res.23 ( 3 ), 513 – 517 ( 2017 ).
   PubMed Web of Science ®Google Scholar
• Da Silva Martinelli CM , Van Helvoort LengertA , MavignierF . MGMT and CALCA promoter methylation are associated with poor prognosis in testicular germ cell tumor patients . Oncotarget8 ( 31 ), 50608 – 50617 ( 2017 ).
   PubMedGoogle Scholar
• Ellinger J , AlbersP , PeraboFG , MüllerSC , Von RueckerA , BastianPJ . CpG island hypermethylation of cell-free circulating serum DNA in patients with testicular cancer . J. Urol.182 ( 1 ), 324 – 329 ( 2009 ).
   PubMed Web of Science ®Google Scholar