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Research Article

Circular RNA Profile of Breast Cancer Brain Metastasis: Identification of Potential Biomarkers and Therapeutic Targets

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Pages 1619-1630 | Received 21 Jun 2018, Accepted 23 Jul 2018, Published online: 06 Dec 2018

References

  • Witzel I , Oliveira-FerrerL , PantelK , MullerV , WikmanH . Breast cancer brain metastases: biology and new clinical perspectives . Breast Cancer Res.18 ( 1 ), 8 ( 2016 ).
  • Mustafa DAM , PedrosaR , SmidMet al. T lymphocytes facilitate brain metastasis of breast cancer by inducing guanylate-binding protein 1 expression . Acta Neuropathol.135 ( 4 ), 581 – 599 ( 2018 ).
  • Lowery FJ , YuD . Brain metastasis: unique challenges and open opportunities . Biochim. Biophys. Acta1867 ( 1 ), 49 – 57 ( 2017 ).
  • Schulten HJ , BangashM , KarimSet al. Comprehensive molecular biomarker identification in breast cancer brain metastases . J. Transl. Med.15 ( 1 ), 269 ( 2017 ).
  • Chen S , ZhaoY . Circular RNAs: characteristics, function, and role in human cancer . Histol. Histopathol.33 ( 9 ), 887 – 893 ( 2018 ).
  • Han B , ChaoJ , YaoH . Circular RNA and its mechanisms in disease: from the bench to the clinic . Pharmacol. Ther.187 , 31 – 44 ( 2018 ).
  • Chen B , HuangS . Circular RNA: An emerging non-coding RNA as a regulator and biomarker in cancer . Cancer Lett.418 , 41 – 50 ( 2018 ).
  • Zhong L , WangY , ChengYet al. Circular RNA circC3P1 suppresses hepatocellular carcinoma growth and metastasis through miR-4641/PCK1 pathway . Biochem. Biophys. Res. Commun.499 ( 4 ), 1044 – 1049 ( 2018 ).
  • Qiu M , XiaW , ChenRet al. The circular RNA circPRKCI promotes tumor growth in lung adenocarcinoma . Cancer Res.78 ( 11 ), 2839 – 2851 ( 2018 ).
  • Zhu M , XuY , ChenY , YanF . Circular BANP, an upregulated circular RNA that modulates cell proliferation in colorectal cancer . Biomed. Pharmacother.88 , 138 – 144 ( 2017 ).
  • Guo S , XuX , OuyangYet al. Microarray expression profile analysis of circular RNAs in pancreatic cancer . Mol. Med. Rep.17 ( 6 ), 7661 – 7671 ( 2018 ).
  • Zhong Z , LvM , ChenJ . Screening differential circular RNA expression profiles reveals the regulatory role of circTCF25-miR-103a-3p/miR-107-CDK6 pathway in bladder carcinoma . Sci. Rep.6 , 30919 ( 2016 ).
  • Yoneda T , WilliamsPJ , HiragaT , NiewolnaM , NishimuraR . A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro . J. Bone Miner. Res.16 ( 8 ), 1486 – 1495 ( 2001 ).
  • Dun MD , ChalkleyRJ , FaulknerSet al. Proteotranscriptomic profiling of 231-BR breast cancer cells: identification of potential biomarkers and therapeutic targets for brain metastasis . Mol. Cell. Proteomics14 ( 9 ), 2316 – 2330 ( 2015 ).
  • Palmieri D , BronderJL , HerringJMet al. Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain . Cancer Res.67 ( 9 ), 4190 – 4198 ( 2007 ).
  • Nie F , YangJ , WenSet al. Involvement of epidermal growth factor receptor overexpression in the promotion of breast cancer brain metastasis . Cancer118 ( 21 ), 5198 – 5209 ( 2012 ).
  • Liu H , KatoY , ErzingerSAet al. The role of MMP-1 in breast cancer growth and metastasis to the brain in a xenograft model . BMC Cancer12 , 583 ( 2012 ).
  • Hohensee I , ChuangHN , GrottkeAet al. PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression . Oncotarget8 ( 4 ), 6155 – 6168 ( 2017 ).
  • Langmead B , TrapnellC , PopM , SalzbergSL . Ultrafast and memory-efficient alignment of short DNA sequences to the human genome . Genome Biol.10 ( 3 ), R25 ( 2009 ).
  • Memczak S , JensM , ElefsiniotiAet al. Circular RNAs are a large class of animal RNAs with regulatory potency . Nature495 ( 7441 ), 333 – 338 ( 2013 ).
  • Gao Y , ZhangJ , ZhaoF . Circular RNA identification based on multiple seed matching . Brief. Bioinform.19 ( 5 ), 803 – 810 ( 2018 ).
  • Zhou L , ChenJ , LiZet al. Integrated profiling of microRNAs and mRNAs: microRNAs located on Xq27.3 associate with clear cell renal cell carcinoma . PLoS ONE5 ( 12 ), e15224 ( 2010 ).
  • Zhou J , ChenH , FanY . Systematic analysis of the expression profile of non-coding RNAs involved in ischemia/reperfusion-induced acute kidney injury in mice using RNA sequencing . Oncotarget8 ( 59 ), 100196 – 100215 ( 2017 ).
  • Young MD , WakefieldMJ , SmythGK , OshlackA . Gene ontology analysis for RNA-seq: accounting for selection bias . Genome Biol.11 ( 2 ), R14 ( 2010 ).
  • Kanehisa M , FurumichiM , TanabeM , SatoY , MorishimaK . KEGG: new perspectives on genomes, pathways, diseases and drugs . Nucleic Acids Res.45 ( D1 ), D353 – D361 ( 2017 ).
  • Sang M , MengL , SangYet al. Circular RNA ciRS-7 accelerates ESCC progression through acting as a miR-876-5p sponge to enhance MAGE-A family expression . Cancer Lett.426 , 37 – 46 ( 2018 ).
  • Jiang W , WenD , GongL , WangY , LiuZ , YinF . Circular RNA hsa_circ_0000673 promotes hepatocellular carcinoma malignance by decreasing miR-767-3p targeting SET . Biochem. Biophys. Res. Commun.500 ( 2 ), 211 – 216 ( 2018 ).
  • Jiang MM , MaiZT , WanSZet al. Microarray profiles reveal that circular RNA hsa_circ_0007385 functions as an oncogene in non-small cell lung cancer tumorigenesis . J. Cancer Res. Clin. Oncol.144 ( 4 ), 667 – 674 ( 2018 ).
  • Zhang J , ZhaoX , ZhangJ , ZhengX , LiF . Circular RNA hsa_circ_0023404 exerts an oncogenic role in cervical cancer through regulating miR-136/TFCP2/YAP pathway . Biochem. Biophys. Res. Commun.501 ( 2 ), 428 – 433 ( 2018 ).
  • Wu J , JiangZ , ChenCet al. CircIRAK3 sponges miR-3607 to facilitate breast cancer metastasis . Cancer Lett.430 , 179 – 192 ( 2018 ).
  • Zhou J , ZhangWW , PengF , SunJY , HeZY , WuSG . Downregulation of hsa_circ_0011946 suppresses the migration and invasion of the breast cancer cell line MCF-7 by targeting RFC3 . Cancer Manag. Res.10 , 535 – 544 ( 2018 ).
  • Xing F , SharmaS , LiuYet al. miR-509 suppresses brain metastasis of breast cancer cells by modulating RhoC and TNF-alpha . Oncogene34 ( 37 ), 4890 – 4900 ( 2015 ).
  • Saunus JM , QuinnMC , PatchAMet al. Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance . J. Pathol.237 ( 3 ), 363 – 378 ( 2015 ).

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