miRNA Deregulation in Childhood Acute Lymphoblastic Leukemia: A Systematic Review

References

• Woo JS , AlbertiMO , TiradoCA. Childhood B-acute lymphoblastic leukemia: a genetic update. Exp. Hematol. Oncol.3, 16 (2014).
   PubMedGoogle Scholar
• Moriyama T , RellingMV , YangJJ. Inherited genetic variation in childhood acute lymphoblastic leukemia. Blood125(26), 3988–3995 (2015).
   PubMed Web of Science ®Google Scholar
• Kaneko Y , HayashiY , SakuraiM. Chromosomal findings and their correlation to prognosis in acute lymphocytic leukemia. Cancer Genet. Cytogenet.4(3), 227–235 (1981).
   PubMedGoogle Scholar
• Paulsson K , LilljebjörnH , BiloglavAet al. The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia. Nat. Genet.47(6), 672–676 (2015).
   PubMed Web of Science ®Google Scholar
• Pui CH , RellingMV , DowningJR. Acute lymphoblastic leukemia. N. Engl. J. Med.350(15), 1535–1548 (2004).
   PubMed Web of Science ®Google Scholar
• Moorman AV , EnsorHM , RichardsSMet al. Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trial. Lancet Oncol.11(5), 429–438 (2010).
   PubMed Web of Science ®Google Scholar
• Mullighan CG . Molecular genetics of B-precursor acute lymphoblastic leukemia. J. Clin. Invest.122(10), 3407–3415 (2012).
   PubMed Web of Science ®Google Scholar
• Caron M , St-OngeP , DrouinSet al. Very long intergenic non-coding RNA transcripts and expression profiles are associated to specific childhood acute lymphoblastic leukemia subtypes. PLoS ONE13(11), e0207250 (2018).
   PubMed Web of Science ®Google Scholar
• Lilljebjörn H , HenningssonR , Hyrenius-WittstenAet al. Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia. Nat. Commun.7, 11790 (2016).
   PubMed Web of Science ®Google Scholar
• Haferlach T , KohlmannA , WieczorekLet al. Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group. J. Clin. Oncol.28(15), 2529–2537 (2010).
   PubMed Web of Science ®Google Scholar
• Gutierrez-Camino A , Martin-GuerreroI , García-OradA. Genetic susceptibility in childhood acute lymphoblastic leukemia. Med. Oncol.34(10), 179 (2017).
   PubMed Web of Science ®Google Scholar
• Ryan BM , RoblesAI , HarrisCC. Genetic variation in microRNA networks: the implications for cancer research. Nat. Rev. Cancer10(6), 389–402 (2010).
   PubMed Web of Science ®Google Scholar
• Churov A , SummerhillV , GrechkoA , OrekhovaV , OrekhovA. MicroRNAs as potential biomarkers in atherosclerosis. Int. J. Mol. Sci.20(22), E5547 (2019).
   PubMed Web of Science ®Google Scholar
• Johanson TM , SkinnerJP , KumarA , ZhanY , LewAM , ChongMM. The role of microRNAs in lymphopoiesis. Int. J. Hematol.100(3), 246–253 (2014).
   PubMed Web of Science ®Google Scholar
• Gutierrez-Camino A , Martin-GuerreroI , DolzanVet al. Involvement of SNPs in miR-3117 and miR-3689d2 in childhood acute lymphoblastic leukemia risk. Oncotarget9(33), 22907–22914 (2018).
   PubMedGoogle Scholar
• Xiao C , SrinivasanL , CaladoDPet al. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat. Immunol.9(4), 405–414 (2008).
   PubMed Web of Science ®Google Scholar
• Musilova K , MrazM. MicroRNAs in B-cell lymphomas: how a complex biology gets more complex. Leukemia29(5), 1004–1017 (2015).
   PubMed Web of Science ®Google Scholar
• Neilson JR , ZhengGX , BurgeCB , SharpPA. Dynamic regulation of miRNA expression in ordered stages of cellular development. Genes Dev.21(5), 578–589 (2007).
   PubMed Web of Science ®Google Scholar
• Sun X , SitA , FeinbergMW. Role of miR-181 family in regulating vascular inflammation and immunity. Trends Cardiovasc. Med.24(3), 105–112 (2014).
   PubMed Web of Science ®Google Scholar
• Wallace JA , O’ConnellRM. MicroRNAs and acute myeloid leukemia: therapeutic implications and emerging concepts. Blood130(11), 1290–1301 (2017).
   PubMed Web of Science ®Google Scholar
• Ultimo S , MartelliAM , ZauliG , VitaleM , CalinGA , NeriLM. Roles and clinical implications of microRNAs in acute lymphoblastic leukemia. J. Cell Physiol.233(8), 5642–5654 (2018).
   PubMed Web of Science ®Google Scholar
• Schotte D , DeMenezes RX , AkbariMoqadam Fet al. MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia. Haematologica96(5), 703–711 (2011).
   PubMed Web of Science ®Google Scholar
• de Oliveira JC , ScrideliCA , BrassescoMSet al. Differential miRNA expression in childhood acute lymphoblastic leukemia and association with clinical and biological features. Leuk. Res.36(3), 293–298 (2012).
   PubMed Web of Science ®Google Scholar
• Renou L , BoellePY , DeswarteCet al. Homeobox protein TLX3 activates miR-125b expression to promote T-cell acute lymphoblastic leukemia. Blood Adv.1(12), 733–747 (2017).
   PubMed Web of Science ®Google Scholar
• Borze I , GuledM , MusseSet al. MicroRNA microarrays on archive bone marrow core biopsies of leukemias–method validation. Leuk. Res.35(2), 188–195 (2011).
   PubMed Web of Science ®Google Scholar
• Zhang H , YangJH , ZhengYSet al. Genome-wide analysis of small RNA and novel MicroRNA discovery in human acute lymphoblastic leukemia based on extensive sequencing approach. PLoS ONE4(9), e6849 (2009).
   PubMed Web of Science ®Google Scholar
• Nemes K , CsókaM , NagyNet al. Expression of certain leukemia/lymphoma related microRNAs and its correlation with prognosis in childhood acute lymphoblastic leukemia. Pathol. Oncol. Res.21(3), 597–604 (2015).
   PubMed Web of Science ®Google Scholar
• Duyu M , DurmazB , GunduzCet al. Prospective evaluation of whole genome microRNA expression profiling in childhood acute lymphoblastic leukemia. Biomed. Res. Int.2014, 967585 (2014).
   PubMed Web of Science ®Google Scholar
• Schotte D , ChauJC , SylvesterGet al. Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia. Leukemia23(2), 313–322 (2009).
   PubMed Web of Science ®Google Scholar
• Li XJ , LuoXQ , HanBW , DuanFT , WeiPP , ChenYQ. MicroRNA-100/99a, deregulated in acute lymphoblastic leukaemia, suppress proliferation and promote apoptosis by regulating the FKBP51 and IGF1R/mTOR signalling pathways. Br. J. Cancer109(8), 2189–2198 (2013).
   PubMed Web of Science ®Google Scholar
• Akbari Moqadam F , Lange-TurenhoutEA , AriësIM , PietersR , den BoerML. MiR-125b, miR-100 and miR-99a co-regulate vincristine resistance in childhood acute lymphoblastic leukemia. Leuk. Res.37(10), 1315–1321 (2013).
   PubMed Web of Science ®Google Scholar
• Zhang H , LuoXQ , ZhangPet al. MicroRNA patterns associated with clinical prognostic parameters and CNS relapse prediction in pediatric acute leukemia. PLoS ONE4(11), e7826 (2009).
   PubMed Web of Science ®Google Scholar
• Akbari Moqadam F , BoerJM , Lange-TurenhoutEA , PietersR , den BoerML. Altered expression of miR-24, miR-126 and miR-365 does not affect viability of childhood TCF3-rearranged leukemia cells. Leukemia28(5), 1008–1014 (2014).
   PubMed Web of Science ®Google Scholar
• Akbari Moqadam F , Lange-TurenhoutEA , vander Veer Aet al. MicroRNA signature in BCR-ABL1-like and BCR-ABL1-positive childhood acute lymphoblastic leukemia: similarities and dissimilarities. Leuk. Lymphoma55(8), 1942–1945 (2014).
   PubMed Web of Science ®Google Scholar
• Avigad S , VerlyIR , LebelAet al. miR expression profiling at diagnosis predicts relapse in pediatric precursor B-cell acute lymphoblastic leukemia. Genes Chromosomes Cancer55(4), 328–339 (2016).
   PubMed Web of Science ®Google Scholar
• Bhatia S , KaulD , VarmaN. Functional genomics of tumor suppressor miR-196b in T-cell acute lymphoblastic leukemia. Mol. Cell Biochem.346(1–2), 103–116 (2011).
   PubMed Web of Science ®Google Scholar
• Cao L , WangN , PanJet al. Clinical significance of microRNA-34b expression in pediatric acute leukemia. Mol. Med. Rep.13(3), 2777–2784 (2016).
   PubMed Web of Science ®Google Scholar
• Chen P , ShenT , WangHet al. MicroRNA-185-5p restores glucocorticoid sensitivity by suppressing the mammalian target of rapamycin complex (mTORC) signaling pathway to enhance glucocorticoid receptor autoregulation. Leuk. Lymphoma.58(11)1–11 (2017).
   PubMed Web of Science ®Google Scholar
• Diakos C , ZhongS , XiaoYet al. TEL-AML1 regulation of survivin and apoptosis via miRNA-494 and miRNA-320a. Blood116(23), 4885–4893 (2010).
   PubMed Web of Science ®Google Scholar
• Doerrenberg M , KloetgenA , HezavehKet al. T-cell acute lymphoblastic leukemia in infants has distinct genetic and epigenetic features compared to childhood cases. Genes Chromosomes Cancer56(2), 159–167 (2017).
   PubMed Web of Science ®Google Scholar
• Gefen N , BinderV , ZaliovaMet al. Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53. Leukemia24(1), 89–96 (2010).
   PubMed Web of Science ®Google Scholar
• Ghodousi ES , RahgozarS. MicroRNA-326 and microRNA-200c: Two novel biomarkers for diagnosis and prognosis of pediatric acute lymphoblastic leukemia. J. Cell Biochem.119(7), 6024–6032 (2018).
   PubMed Web of Science ®Google Scholar
• Han BW , FengDD , LiZGet al. A set of miRNAs that involve in the pathways of drug resistance and leukemic stem-cell differentiation is associated with the risk of relapse and glucocorticoid response in childhood ALL. Hum. Mol. Genet.20(24), 4903–4915 (2011).
   PubMed Web of Science ®Google Scholar
• Ju X , LiD , ShiQ , HouH , SunN , ShenB. Differential microRNA expression in childhood B-cell precursor acute lymphoblastic leukemia. Pediatr. Hematol. Oncol.26(1), 1–10 (2009).
   PubMed Web of Science ®Google Scholar
• Kaddar T , ChienWW , BertrandYet al. Prognostic value of miR-16 expression in childhood acute lymphoblastic leukemia relationships to normal and malignant lymphocyte proliferation. Leuk. Res.33(9), 1217–1223 (2009).
   PubMed Web of Science ®Google Scholar
• Krzanowski J , MadzioJ , PastorczakAet al. Selected miRNA levels are associated with. Oncol. Lett.14(3), 3853–3861 (2017).
   PubMed Web of Science ®Google Scholar
• Labib HA , ElantounyNG , IbrahimNF , AlnagarAA. Upregulation of microRNA-21 is a poor prognostic marker in patients with childhood B cell acute lymphoblastic leukemia. Hematology22(7), 392–397 (2017).
   PubMed Web of Science ®Google Scholar
• Li X , SandaT , LookAT , NovinaCD , von BoehmerH. Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL. J. Exp. Med.208(4), 663–675 (2011).
   PubMed Web of Science ®Google Scholar
• Liang YN , TangYL , KeZYet al. MiR-124 contributes to glucocorticoid resistance in acute lymphoblastic leukemia by promoting proliferation, inhibiting apoptosis and targeting the glucocorticoid receptor. J. Steroid Biochem. Mol. Biol.172, 62–68 (2017).
   PubMed Web of Science ®Google Scholar
• Lou Y , LiuL , ZhanL , WangX , FanH. miR-187-5p regulates cell growth and apoptosis in acute lymphoblastic leukemia via DKK2. Oncol. Res.24(2), 89–97 (2016).
   PubMed Web of Science ®Google Scholar
• Malik D , KaulD , ChauhanN , MarwahaRK. miR-2909-mediated regulation of KLF4: a novel molecular mechanism for differentiating between B-cell and T-cell pediatric acute lymphoblastic leukemias. Mol. Cancer13, 175 (2014).
   PubMed Web of Science ®Google Scholar
• Mansour MR , SandaT , LawtonLNet al. The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia. J. Exp. Med.210(8), 1545–1557 (2013).
   PubMed Web of Science ®Google Scholar
• Mei Y , GaoC , WangKet al. Effect of microRNA-210 on prognosis and response to chemotherapeutic drugs in pediatric acute lymphoblastic leukemia. Cancer Sci.105(4), 463–472 (2014).
   PubMed Web of Science ®Google Scholar
• Mosakhani N , SarhadiVK , UsvasaloAet al. MicroRNA profiling in pediatric acute lymphoblastic leukemia: novel prognostic tools. Leuk. Lymphoma53(12), 2517–2520 (2012).
   PubMed Web of Science ®Google Scholar
• Nabhan M , LoukaML , KhairyE , TashF , Ali-LabibR , El-HabashyS. MicroRNA-181a and its target Smad 7 as potential biomarkers for tracking child acute lymphoblastic leukemia. Gene628, 253–258 (2017).
   PubMed Web of Science ®Google Scholar
• Nishi M , Eguchi-IshimaeM , WuZet al. Suppression of the let-7b microRNA pathway by DNA hypermethylation in infant acute lymphoblastic leukemia with MLL gene rearrangements. Leukemia27(2), 389–397 (2013).
   PubMed Web of Science ®Google Scholar
• de Oliveira JC , ScrideliCA , BrassescoMS , YunesJA , BrandaliseSR , ToneLG. MiR-708-5p is differentially expressed in childhood acute lymphoblastic leukemia but not strongly associated to clinical features. Pediatr. Blood Cancer62(1), 177–178 (2015).
   PubMed Web of Science ®Google Scholar
• Organista-Nava J , Gómez-GómezY , Illades-AguiarBet al. High miR-24 expression is associated with risk of relapse and poor survival in acute leukemia. Oncol. Rep.33(4), 1639–1649 (2015).
   PubMed Web of Science ®Google Scholar
• Piatopoulou D , AvgerisM , MarmarinosAet al. miR-125b predicts childhood acute lymphoblastic leukaemia poor response to BFM chemotherapy treatment. Br. J. Cancer117(6), 801–812 (2017).
   PubMed Web of Science ®Google Scholar
• Schotte D , AkbariMoqadam F , Lange-TurenhoutEAet al. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. Leukemia25(9), 1389–1399 (2011).
   PubMed Web of Science ®Google Scholar
• Schotte D , Lange-TurenhoutEA , StumpelDJet al. Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia. Haematologica95(10), 1675–1682 (2010).
   PubMed Web of Science ®Google Scholar
• Swellam M , El-KhazragyN. Clinical impact of circulating microRNAs as blood-based marker in childhood acute lymphoblastic leukemia. Tumour Biol.37(8), 10571–10576 (2016).
   PubMedGoogle Scholar
• Tassano E , AcquilaM , TavellaE , MicalizziC , PanarelloC , MorerioC. MicroRNA-125b-1 and BLID upregulation resulting from a novel IGH translocation in childhood B-Cell precursor acute lymphoblastic leukemia. Genes Chromosomes Cancer49(8), 682–687 (2010).
   PubMed Web of Science ®Google Scholar
• Vendramini E , GiordanM , GiarinEet al. High expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia. Oncotarget8(26), 42398–42413 (2017).
   PubMedGoogle Scholar
• Yan J , JiangN , HuangGet al. Deregulated MIR335 that targets MAPK1 is implicated in poor outcome of paediatric acute lymphoblastic leukaemia. Br. J. Haematol.163(1), 93–103 (2013).
   PubMed Web of Science ®Google Scholar
• Yu L , SlovakML , MannoorKet al. Microarray detection of multiple recurring submicroscopic chromosomal aberrations in pediatric T-cell acute lymphoblastic leukemia. Leukemia25(6), 1042–1046 (2011).
   PubMed Web of Science ®Google Scholar
• Yang Y , XuJ , ChenHet al. MiR-128-2 inhibits common lymphoid progenitors from developing into progenitor B cells. Oncotarget7(14), 17520–17531 (2016).
   PubMedGoogle Scholar
• Mets E , Van PeerG , Vander Meulen Jet al. MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia. Haematologica99(8), 1326–1333 (2014).
   PubMed Web of Science ®Google Scholar
• Mi S , LuJ , SunMet al. MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia. Proc. Natl Acad. Sci. USA104(50), 19971–19976 (2007).
   PubMed Web of Science ®Google Scholar
• Zhu YD , WangL , SunCet al. Distinctive microRNA signature is associated with the diagnosis and prognosis of acute leukemia. Med. Oncol.29(4), 2323–2331 (2012).
   PubMed Web of Science ®Google Scholar
• Pons A , NomdedeuB , NavarroAet al. Hematopoiesis-related microRNA expression in myelodysplastic syndromes. Leuk. Lymphoma50(11), 1854–1859 (2009).
   PubMed Web of Science ®Google Scholar
• Pichiorri F , SuhSS , LadettoMet al. MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis. Proc. Natl Acad. Sci. USA105(35), 12885–12890 (2008).
   PubMed Web of Science ®Google Scholar
• Su R , LinHS , ZhangXHet al. MiR-181 family: regulators of myeloid differentiation and acute myeloid leukemia as well as potential therapeutic targets. Oncogene34(25), 3226–3239 (2015).
   PubMed Web of Science ®Google Scholar
• Chen CZ , LiL , LodishHF , BartelDP. MicroRNAs modulate hematopoietic lineage differentiation. Science303(5654), 83–86 (2004).
   PubMed Web of Science ®Google Scholar
• Cichocki F , FelicesM , McCullarVet al. Cutting edge: microRNA-181 promotes human NK cell development by regulating Notch signaling. J. Immunol.187(12), 6171–6175 (2011).
   PubMed Web of Science ®Google Scholar
• Lyu X , LiJ , YunXet al. miR-181a-5p, an inducer of Wnt-signaling, facilitates cell proliferation in acute lymphoblastic leukemia. Oncol. Rep.37(3), 1469–1476 (2017).
   PubMed Web of Science ®Google Scholar
• Verduci L , AzzalinG , GioiosaSet al. microRNA-181a enhances cell proliferation in acute lymphoblastic leukemia by targeting EGR1. Leuk. Res.39(4), 479–485 (2015).
   PubMed Web of Science ®Google Scholar
• Thai TH , CaladoDP , CasolaSet al. Regulation of the germinal center response by microRNA-155. Science316(5824), 604–608 (2007).
   PubMed Web of Science ®Google Scholar
• Zhang Y , LiH , CaoRet al. Suppression of miR-708 inhibits the Wnt/β-catenin signaling pathway by activating DKK3 in adult B-all. Oncotarget8(38), 64114–64128 (2017).
   PubMedGoogle Scholar
• Zhang L , LiX , KeZet al. MiR-99a may serve as a potential oncogene in pediatric myeloid leukemia. Cancer Cell Int.13(1), 110 (2013).
   PubMedGoogle Scholar
• Chao MP , AlizadehAA , TangCet al. Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia. Cancer Res.71(4), 1374–1384 (2011).
   PubMed Web of Science ®Google Scholar
• Huang W , WangWT , FangKet al. MIR-708 promotes phagocytosis to eradicate T-ALL cells by targeting CD47. Mol. Cancer17(1), 12 (2018).
   PubMedGoogle Scholar
• La Starza R , BarbaG , DemeyerSet al. Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia. Haematologica101(8), 951–958 (2016).
   PubMed Web of Science ®Google Scholar
• He Y , JiangX , ChenJ. The role of miR-150 in normal and malignant hematopoiesis. Oncogene33(30), 3887–3893 (2014).
   PubMed Web of Science ®Google Scholar
• Vergani E , DiGuardo L , DugoMet al. Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b. Oncotarget7(4), 4428–4441 (2016).
   PubMedGoogle Scholar
• Kandi R , GuttiU , SaladiRG , GuttiRK. MiR-125b and miR-99a encoded on chromosome 21 co-regulate vincristine resistance in childhood acute megakaryoblastic leukemia. Hematol. Oncol. Stem Cell Ther.8(2), 95–97 (2015).
   PubMedGoogle Scholar
• Umerez M , Garcia-ObregonS , Martin-GuerreroI , AstigarragaI , Gutierrez-CaminoA , Garcia-OradA. Role of miRNAs in treatment response and toxicity of childhood acute lymphoblastic leukemia. Pharmacogenomics19(4), 361–373 (2018).
   PubMed Web of Science ®Google Scholar