195
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Molecular Function Predictions and Diagnostic Value Analysis of Plasma Exosomal miRNAs in Hirschsprung’s Disease

, , , , , & show all
Pages 409-422 | Received 08 Jul 2019, Accepted 17 Jan 2020, Published online: 16 Apr 2020

References

  • Ray K . Enteric nervous system: modelling and treating Hirschsprung disease: stem cells to the rescue?Nat. Rev. Gastroenterol. Hepatol.13(4), 187 (2016).
  • Heanue TA , PachnisV. Enteric nervous system development and Hirschsprung’s disease: advances in genetic and stem cell studies. Nat. Rev. Neurosci.8(6), 466–479 (2007).
  • Mccabe ER . Hirschsprung’s disease: dissecting complexity in a pathogenetic network. Lancet359(9313), 1169–1170 (2002).
  • Sribudiani Y , ChauhanRK , AlvesMMet al. Identification of variants in RET and IHH pathway members in a large family with history of Hirschsprung disease. Gastroenterology155(1), 118–129 (2018).
  • Gui H , SchriemerD , ChengWWet al. Whole exome sequencing coupled with unbiased functional analysis reveals new Hirschsprung disease genes. Genome Biol.18(1), 48 (2017).
  • Heuckeroth RO . Hirschsprung disease – integrating basic science and clinical medicine to improve outcomes. Nat. Rev. Gastroenterol. Hepatol.15(3), 152–167 (2018).
  • Bracken CP , ScottHS , GoodallGJ. A network-biology perspective of microRNA function and dysfunction in cancer. Nat. Rev. Genet.17(12), 719–732 (2016).
  • Patel M , VermaA , AslamI , PringleH , SinghB. Novel plasma microRNA biomarkers for the identification of colitis-associated carcinoma. Lancet385(Suppl. 1), S78 (2015).
  • Verma AM , PatelM , AslamMIet al. Circulating plasma microRNAs as a screening method for detection of colorectal adenomas. Lancet385(Suppl. 1), S100 (2015).
  • Tang W , LiH , TangJet al. Specific serum microRNA profile in the molecular diagnosis of Hirschsprung’s disease. J. Cell Mol. Med.18(8), 1580–1587 (2014).
  • Raposo G , StoorvogelW. Extracellular vesicles: exosomes, microvesicles, and friends. J. Cell Biol.200(4), 373–383 (2013).
  • Sohn W , KimJ , KangSHet al. Serum exosomal microRNAs as novel biomarkers for hepatocellular carcinoma. Exp. Mol. Med.47, e184 (2015).
  • Valadi H , EkstromK , BossiosA , SjostrandM , LeeJJ , LotvallJO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol.9(6), 654–659 (2007).
  • Budnik V , Ruiz-CanadaC , WendlerF. Extracellular vesicles round off communication in the nervous system. Nat. Rev. Neurosci.17(3), 160–172 (2016).
  • Lee YR , KimG , TakWYet al. Circulating exosomal noncoding RNAs as prognostic biomarkers in human hepatocellular carcinoma. Int. J. Cancer144(6), 1444–1452 (2019).
  • Kalluri R . The biology and function of exosomes in cancer. J. Clin. Invest.126(4), 1208–1215 (2016).
  • Yang B , ChenY , ShiJ. Exosome biochemistry and advanced nanotechnology for next-generation theranostic platforms. Adv. Mater.31(2), e1802896 (2019).
  • Munagala R , AqilF , JeyabalanJ , GuptaRC. Bovine milk-derived exosomes for drug delivery. Cancer Lett.371(1), 48–61 (2016).
  • Mitchell PS , ParkinRK , KrohEMet al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc. Natl Acad. Sci. USA105(30), 10513–10518 (2008).
  • Li Y , ZhouL , LuCet al. Long non-coding RNA FAL1 functions as a ceRNA to antagonize the effect of miR-637 on the down-regulation of AKT1 in Hirschsprung’s disease. Cell Prolif.51(5), e12489 (2018).
  • Zhou L , LiY , JiangWet al. Down-regulation of circ-PRKCI inhibits cell migration and proliferation in Hirschsprung disease by suppressing the expression of miR-1324 target PLCB1. Cell Cycle17(9), 1092–1101 (2018).
  • Tilghman JM , LingAY , TurnerTNet al. Molecular genetic anatomy and risk profile of Hirschsprung’s disease. N. Engl. J. Med.380(15), 1421–1432 (2019).
  • Fattahi F , SteinbeckJA , KriksSet al. Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease. Nature531(7592), 105–109 (2016).
  • Nabi Z , ShavaU , SekharanA , NageshwarReddy D. Diagnosis of Hirschsprung’s disease in children: preliminary evaluation of a novel endoscopic technique for rectal biopsy. JGH Open2(6), 322–326 (2018).
  • Rosenfield NS , AblowRC , MarkowitzRIet al. Hirschsprung disease: accuracy of the barium enema examination. Radiology150(2), 393–400 (1984).
  • Lanfranchi GA , BazzocchiG , FedericiSet al. Anorectal manometry in the diagnosis of Hirschsprung’s disease--comparison with clinical and radiological criteria. Am. J. Gastroenterol.79(4), 270–275 (1984).
  • Meinds RJ , KuiperGA , ParryKet al. Infant’s age influences the accuracy of rectal suction biopsies for diagnosing of Hirschsprung’s disease. Clin. Gastroenterol. Hepatol.13(10), 1801–1807 (2015).
  • Whiteside TL . The emerging role of plasma exosomes in diagnosis, prognosis and therapies of patients with cancer. Contemp. Oncol. (Pozn)22(1A), 38–40 (2018).
  • Faure J , LachenalG , CourtMet al. Exosomes are released by cultured cortical neurones. Mol. Cell. Neurosci.31(4), 642–648 (2006).
  • Fruhbeis C , FrohlichD , KuoWPet al. Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol.11(7), e1001604 (2013).
  • Lachenal G , Pernet-GallayK , ChivetMet al. Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity. Mol. Cell. Neurosci.46(2), 409–418 (2011).
  • O’donnell AM , NakamuraH , TomuschatC , MarayatiNF , PuriP. Altered expression of KCNG3 and KCNG4 in Hirschsprung’s disease. Pediatr. Surg. Int.35(2), 193–197 (2019).
  • Fan L , LuY , ShenX , ShaoH , SuoL , WuQ. α protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice. Elife7, e35242 (2018).
  • Chen G , PengL , ZhuZet al. LncRNA AFAP1-AS functions as a competing endogenous RNA to regulate RAP1B expression by sponging miR-181a in the HSCR. Int. J. Med. Sci.14(10), 1022–1030 (2017).
  • Soret R , MennetreyM , BergeronKFet al. A collagen VI-dependent pathogenic mechanism for Hirschsprung’s disease. J. Clin. Invest.125(12), 4483–4496 (2015).
  • Xia H , NhoRS , KahmJ , KleidonJ , HenkeCA. Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a β 1 integrin viability signaling pathway. J. Biol. Chem.279(31), 33024–33034 (2004).
  • Reif S , LangA , LindquistJNet al. The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression. J. Biol. Chem.278(10), 8083–8090 (2003).
  • Li L , ChenHZ , ChenFFet al. Global microRNA expression profiling reveals differential expression of target genes in 6-hydroxydopamine-injured MN9D cells. Neuromolecular Med.15(3), 593–604 (2013).
  • Li J , XuX , MengSet al. MET/SMAD3/SNAIL circuit mediated by miR-323a-3p is involved in regulating epithelial–mesenchymal transition progression in bladder cancer. Cell Death Dis.8(8), e3010 (2017).
  • Zeng Z , ZhouW , DuanLet al. Circular RNA circ-VANGL1 as a competing endogenous RNA contributes to bladder cancer progression by regulating miR-605-3p/VANGL1 pathway. J. Cell. Physiol.234(4), 3887–3896 (2019).
  • Prajapati P , SripadaL , SinghKet al. Systemic analysis of miRNAs in PD stress condition: miR-5701 modulates mitochondrial-lysosomal cross talk to regulate neuronal death. Mol. Neurobiol.55(6), 4689–4701 (2018).
  • Venugopal C , KS , RaiKS , PinnelliVB , KuttyBM , DhanushkodiA. Neuroprotection by human dental pulp mesenchymal stem cells: from billions to nano. Curr. Gene Ther.18(5), 307–323 (2018).
  • Du C , XieH , ZangRet al. Apoptotic neuron-secreted HN12 inhibits cell apoptosis in Hirschsprung’s disease. Int. J. Nanomedicine11, 5871–5881 (2016).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.