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Research Article

CLDN10 Associated with Immune Infiltration is a Novel Prognostic Biomarker for Clear Cell Renal Cell Carcinoma

ORCID Icon, , , , , & ORCID Icon show all
Pages 31-45 | Received 21 Jun 2020, Accepted 23 Oct 2020, Published online: 18 Nov 2020

References

  • Siegel RL , MillerKD , JemalA. Cancer statistics, 2020. CA Cancer J Clin.70(1), 7–30 (2020).
  • Hsieh JJ , PurdueMP , SignorettiSet al. Renal cell carcinoma. Nat. Rev. Dis. Primers3, 17009 (2017).
  • Moch H , CubillaAL , HumphreyPAet al. The 2016 WHO classification of tumours of the urinary system and male genital organs—part A: renal, penile, and testicular tumours. Eur. Urol.70(1), 93–105 (2016).
  • Patard JJ , PignotG , EscudierBet al. ICUD-EAU International Consultation on Kidney Cancer 2010: treatment of metastatic disease. Eur. Urol.60(4), 684–690 (2011).
  • Capitanio U , MontorsiF. Renal cancer. Lancet387(10021), 894–906 (2016).
  • Rini BI , CampbellSC , EscudierB. Renal cell carcinoma. Lancet373(9669), 1119–1132 (2009).
  • Janzen NK , KimHL , FiglinRA , BelldegrunAS. Surveillance after radical or partial nephrectomy for localized renal cell carcinoma and management of recurrent disease. Urol. Clin. North Am.30(4), 843–852 (2003).
  • Choueiri TK , MotzerRJ. Systemic therapy for metastatic renal-cell carcinoma. New Engl. J. Med.376(4), 354–366 (2017).
  • Hirohashi S , KanaiY. Cell adhesion system and human cancer morphogenesis. Cancer Sci.94(7), 575–581 (2003).
  • Tsukita S , FuruseM , ItohM. Multifunctional strands in tight junctions. Nat. Rev. Mol. Cell Biol.2(4), 285–293 (2001).
  • Huang GW , DingX , ChenSL , ZengL. Expression of claudin 10 protein in hepatocellular carcinoma: Impact on survival. J. Cancer Res. Clin. Oncol.137(8), 1213–1218 (2011).
  • Zhou Y , XiangJ , BhandariAet al. CLDN10 is associated with papillary thyroid cancer progression. J. Cancer9(24), 4712–4717 (2018).
  • Yang W , ZhangK , LiLet al. Discovery and validation of the prognostic value of the lncRNAs encoding snoRNAs in patients with clear cell renal cell carcinoma. Aging12(5), 4424–4444 (2020).
  • Şenbabaoğlu Y , GejmanRS , WinerAGet al. Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures. Genome Biology17(1), 231 (2016).
  • Yoshihara K , ShahmoradgoliM , MartinezEet al. Inferring tumour purity and stromal and immune cell admixture from expression data. Nat. Commun.4, 2612 (2013).
  • Thompson RH , DongH , LohseCMet al. PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma. Clin. Cancer Res.13(6), 1757–1761 (2007).
  • Xiang Z , ZhongC , ChangAet al. Immune-related key gene CLDN10 correlates with lymph node metastasis but predicts favorable prognosis in papillary thyroid carcinoma. Aging12(3), 2825–2839 (2020).
  • Xu L , DengC , PangBet al. TIP: a web server for resolving tumor immunophenotype profiling. Cancer Res.78(23), 6575–6580 (2018).
  • Swisshelm K , MacekR , KubbiesM. Role of claudins in tumorigenesis. Adv. Drug Delivery Rev.57(6), 919–928 (2005).
  • Kominsky SL . Claudins: emerging targets for cancer therapy. Exp. Rev. Mol. Med.8(18), 1–11 (2006).
  • Luo Y , KishiS , SasakiTet al. Targeting claudin-4 enhances chemosensitivity in breast cancer. Cancer Sci.111(5), 1840–1850 (2020).
  • Cherradi S , Ayrolles-TorroA , Vezzo-VieNet al. Antibody targeting of claudin-1 as a potential colorectal cancer therapy. J. Exp. Clin. Cancer Res.36(1), 89 (2017).
  • Singh P , ToomS , HuangY. Anti-claudin 18.2 antibody as new targeted therapy for advanced gastric cancer. J. Hematol. Oncol.10(1), 105 (2017).
  • Gao Y , LiuX , LiTet al. Cross-validation of genes potentially associated with overall survival and drug resistance in ovarian cancer. Oncol. Rep.37(5), 3084–3092 (2017).
  • Li Y , GongY , NingXet al. Downregulation of CLDN7 due to promoter hypermethylation is associated with human clear cell renal cell carcinoma progression and poor prognosis. J. Exp. Clin. Cancer Res.37(1), 276 (2018).
  • Kwon MJ . Emerging roles of claudins in human cancer. Int. J. Mol. Sci.14(9), 18148–18180 (2013).
  • Honda H , PazinMJ , JiHet al. Crucial roles of Sp1 and epigenetic modifications in the regulation of the CLDN4 promoter in ovarian cancer cells. J. Biol. Chem.281(30), 21433–21444 (2006).
  • Sahin U , KoslowskiM , DhaeneKet al. Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development. Clin. Cancer Res.14(23), 7624–7634 (2008).
  • Ito T , KojimaT , YamaguchiHet al. Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA methylation in human pancreatic cancer cells. J. Cell. Biochem.112(7), 1761–1772 (2011).
  • Liu S , LiS , WangYet al. Prognostic value of infiltrating immune cells in clear cell renal cell carcinoma (ccRCC). J. Cell. Biochem.121(3), 2571–2581 (2020).

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