References
- Stone NJ , RobinsonJG , LichtensteinAHet al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines. J. Am. Coll. Cardiol.63(25, Part B), 2889–2934 (2014).
- Betteridge DJ , CarmenaR. The diabetogenic action of statins – mechanisms and clinical implications. Nat. Rev. Endocrinol.12(2), 99–110 (2016).
- Ochoa-Rosales C , Portilla-FernandezE , NanoJet al. Epigenetic link between statin therapy and Type 2 diabetes. Diabetes Care43(4), 875–884 (2020).
- McCartney DL , WalkerRM , MorrisSW , McIntoshAM , PorteousDJ , EvansKL. Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip. Genomics Data9, 22–24 (2016).
- Houseman EA , MolitorJ , MarsitCJ. Reference-free cell mixture adjustments in analysis of DNA methylation data. Bioinformatics30(10), 1431–1439 (2014).
- Wang J , LiaoY , JaehnigE , ShiZ , ShengQ. WebGestaltR: gene set analysis toolkit WebGestaltR. (2020). https://CRAN.R-project.org/package=WebGestaltR
- Tingley D , YamamotoT , HiroseK , KeeleL , ImaiK. Mediation: r package for causal mediation analysis. J. Stat. Softw.59(5), (2014). http://www.jstatsoft.org/v59/i05/
- R Core Team . R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria, https://www.R-project.org
- Mo X , GuoY , QianQ , FuM , ZhangH. Phosphorylation-related SNPs influence lipid levels and rheumatoid arthritis risk by altering gene expression and plasma protein levels. Rheumatol. Oxf. Engl.59(4), 889–898 (2020).
- Yang Y , WangH , KouadirM , SongH , ShiF. Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors. Cell Death Dis.10(2), 1–11 (2019).
- Greenwood J , SteinmanL , ZamvilSS. Statin therapy and autoimmune disease: from protein prenylation to immunomodulation. Nat. Rev. Immunol.6(5), 358–370 (2006).
- van Iterson M , van ZwetEW , HeijmansBT. the BIOS Consortium. Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution. Genome Biol.18(1), 19 (2017).