Promotional Effects of HIF1α and KDM3A Interaction on Vascular Smooth Muscle Cells in Thoracic Aortic Dissection

References

• Zheng HQ , RongJB , YeFM , XuYC , LuHS , WangJA. Induction of thoracic aortic dissection: a mini-review of beta-aminopropionitrile-related mouse models. J. Zhejiang Univ. Sci. B21(8), 603–610 (2020).
   PubMed Web of Science ®Google Scholar
• Doyle BJ , NormanPE. Computational biomechanics in thoracic aortic dissection: today’s approaches and tomorrow’s opportunities. Ann. Biomed. Eng.44(1), 71–83 (2016).
   PubMed Web of Science ®Google Scholar
• Saremi F , HassaniC , LinLMet al. Image predictors of treatment outcome after thoracic aortic dissection repair. Radiographics38(7), 1949–1972 (2018).
   PubMed Web of Science ®Google Scholar
• Wu D , ShenYH , RussellL , CoselliJS , LeMaireSA. Molecular mechanisms of thoracic aortic dissection. J. Surg. Res.184(2), 907–924 (2013).
   PubMed Web of Science ®Google Scholar
• Uchida T , SadahiroM. Thoracic endovascular aortic repair for acute aortic dissection. Ann. Vasc. Dis.11(4), 464–472 (2018).
   PubMedGoogle Scholar
• Sun Y , ZhaoZ , HouLet al. The regulatory role of smooth muscle 22 on the proliferation of aortic smooth muscle cells participates in the development of aortic dissection. J. Vasc. Surg.66(3), 875–882 (2017).
   PubMed Web of Science ®Google Scholar
• Galbraith MD , AllenMA , BensardCLet al. HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia. Cell153(6), 1327–1339 (2013).
   PubMed Web of Science ®Google Scholar
• Liu K , FangC , ShenYet al. Hypoxia-inducible factor 1a induces phenotype switch of human aortic vascular smooth muscle cell through PI3K/AKT/AEG-1 signaling. Oncotarget8(20), 33343–33352 (2017).
   PubMedGoogle Scholar
• Revollo JR , OakleyRH , LuNZ , KadmielM , GandhavadiM , CidlowskiJA. HES1 is a master regulator of glucocorticoid receptor-dependent gene expression. Sci. Signal6(304), ra103 (2013).
   PubMed Web of Science ®Google Scholar
• Vecera J , ProchazkovaJ , SumberovaVet al. Hypoxia/Hif1alpha prevents premature neuronal differentiation of neural stem cells through the activation of Hes1. Stem Cell Res.45, 101770 (2020).
   PubMedGoogle Scholar
• Zou S , RenP , NguyenM , CoselliJS , ShenYH , LeMaireSA. Notch signaling in descending thoracic aortic aneurysm and dissection. PLoS One7(12), e52833 (2012).
   PubMed Web of Science ®Google Scholar
• Yoo J , JeonYH , ChoHYet al. Advances in Histone Demethylase KDM3A as a Cancer Therapeutic Target. Cancers (Basel)12(5), 2020).
   Web of Science ®Google Scholar
• Wilson S , FanL , SahgalN , QiJ , FilippFV. The histone demethylase KDM3A regulates the transcriptional program of the androgen receptor in prostate cancer cells. Oncotarget8(18), 30328–30343 (2017).
   PubMedGoogle Scholar
• Zhang BF , JiangH , ChenJ , GuoX , HuQ , YangS. KDM3A inhibition attenuates high concentration insulin-induced vascular smooth muscle cell injury by suppressing MAPK/NFkappaB pathways. Int. J. Mol. Med.41(3), 1265–1274 (2018).
   PubMed Web of Science ®Google Scholar
• Aghazadeh S , YazdanparastR. Activation of STAT3/HIF-1alpha/Hes-1 axis promotes trastuzumab resistance in HER2-overexpressing breast cancer cells via down-regulation of PTEN. Biochim. Biophys. Acta. Gen. Subj.1861(8), 1970–1980 (2017).
   PubMed Web of Science ®Google Scholar
• Mimura I , NangakuM , KankiYet al. Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A. Mol. Cell. Biol.32(15), 3018–3032 (2012).
   PubMed Web of Science ®Google Scholar
• Cai C , HeHH , ChenSet al. Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1. Cancer Cell20(4), 457–471 (2011).
   PubMed Web of Science ®Google Scholar
• Clark EA , WuF , ChenYet al. GR and LSD1/KDM1A-targeted gene activation requires selective H3K4me2 demethylation at enhancers. Cell Rep.27(12), 3522–3532; e3523 (2019).
   PubMed Web of Science ®Google Scholar
• Babu AR , ByjuAG , GundiahN. Biomechanical properties of human ascending thoracic aortic dissections. J. Biomech. Eng.137(8), 081013 (2015).
   PubMed Web of Science ®Google Scholar
• Yang YY , LiLY , JiaoXLet al. Intermittent hypoxia alleviates beta-aminopropionitrile monofumarate induced thoracic aortic dissection in C57BL/6 Mice. Eur. J. Vasc. Endovasc. Surg.59(6), 1000–1010 (2020).
   PubMed Web of Science ®Google Scholar
• Le S , ZhangH , HuangXet al. PKM2 activator TEPP-46 attenuates thoracic aortic aneurysm and dissection by inhibiting NLRP3 inflammasome-mediated IL-1beta secretion. J. Cardiovasc. Pharmacol. Ther.25(4), 364–376 (2020).
   PubMed Web of Science ®Google Scholar
• Tsai SH , HuangPH , HsuYJet al. Inhibition of hypoxia inducible factor-1alpha attenuates abdominal aortic aneurysm progression through the down-regulation of matrix metalloproteinases. Sci Rep.6, 28612 (2016).
   PubMed Web of Science ®Google Scholar
• Zheng X , NarayananS , ZhengXet al. A Notch-independent mechanism contributes to the induction of Hes1 gene expression in response to hypoxia in P19 cells. Exp. Cell Res.358(2), 129–139 (2017).
   PubMed Web of Science ®Google Scholar
• Wu JR , YehJL , LiouSF , DaiZK , WuBN , HsuJH. Gamma-secretase inhibitor prevents proliferation and migration of ductus arteriosus smooth muscle cells through the notch3-HES1/2/5 pathway. Int. J. Biol. Sci.12(9), 1063–1073 (2016).
   PubMed Web of Science ®Google Scholar
• Zhang X , LiuS , WengXet al. Brg1 trans-activates endothelium-derived colony stimulating factor to promote calcium chloride induced abdominal aortic aneurysm in mice. J. Mol. Cell. Cardiol.125, 6–17 (2018).
   PubMed Web of Science ®Google Scholar
• Zhang QJ , TranTAT , WangMet al. Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis. Nat. Commun.9(1), 5230 (2018).
   PubMed Web of Science ®Google Scholar
• Imanishi M , ChibaY , TomitaNet al. Hypoxia-inducible factor-1alpha in smooth muscle cells protects against aortic aneurysms-brief report. Arterioscler. Thromb. Vasc. Biol.36(11), 2158–2162 (2016).
   PubMed Web of Science ®Google Scholar
• Pan KL , HsuYC , TungCW , ChangST , ChungCM , LinCL. Inhibition of notch signaling alleviated diabetic macrovasculopathy in an in vitro model. Acta. Cardiol. Sin.36(5), 503–513 (2020).
   PubMed Web of Science ®Google Scholar