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Research Article

SPARCL1 Exhibits Different Expressions in Left- and Right-Sided Colon Cancer and is Downregulated Via DNA Methylation

, , , , , , , , , , & ORCID Icon show all
Pages 1269-1282 | Received 29 Jun 2021, Accepted 10 Aug 2021, Published online: 26 Aug 2021

References

  • Ogino S , NoshoK , KirknerGJet al. CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. Gut58(1), 90–96 (2009).
  • Cancer Genome Atlas Network . Comprehensive molecular characterization of human colon and rectal cancer. Nature487(7407), 330–337 (2012).
  • Li FY , LaiMD. Colorectal cancer, one entity or three. J. Zhejiang Univ. Sci. B.10(3), 219–229 (2009).
  • Di Pietro M , SabatesBellver J , MenigattiMet al. Defective DNA mismatch repair determines a characteristic transcriptional profile in proximal colon cancers. Gastroenterology129(3), 1047–1059 (2005).
  • Gao XH , YuGY , GongHFet al. Differences of protein expression profiles, KRAS and BRAF mutation, and prognosis in right-sided colon, left-sided colon and rectal cancer. Sci. Rep.7(1), 7882 (2017).
  • Arnold D , LuezaB , DouillardJYet al. Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR directed antibodies in six randomized trials. Ann. Oncol.28(8), 1713–1729 (2017).
  • Girard JP , SpringerTA. Cloning from purified high endothelial venule cells of hevin, a close relative of the antiadhesive extracellular matrix protein SPARC. Immunity2(1), 113–123 (1995).
  • Shen C , YinY , ChenHet al. Secreted protein acidic and rich in cysteine-like 1 suppresses metastasis in gastric stromal tumors. BMC Gastroenterol.18(1), 105 (2018).
  • Claeskens A , OngenaeN , NeefsJMet al. Hevin is down-regulated in many cancers and is a negative regulator of cell growth and proliferation. Br. J. Cancer82(6), 1123–1130 (2000).
  • Girard JP , SpringerTA. Modulation of endothelial cell adhesion by hevin, an acidic protein associated with high endothelial venules. J. Biol. Chem.271(8), 4511–4517 (1996).
  • Gongidi V , RingC , MoodyMet al. SPARC-like 1 regulates the terminal phase of radial glia-guided migration in the cerebral cortex. Neuron41(1), 57–69 (2004).
  • Oritani K , KincadePW. Lymphopoiesis and matrix glycoprotein SC1/ECM2. Leuk. Lymphoma32(1-2), 1–7 (1998).
  • Naschberger E , LieblA , SchellererVSet al. Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinoma. J. Clin. Invest.126(11), 4187–4204 (2016).
  • Luo H-L , ChiangP-H , HuangC-Cet al. Methylation of SPARCL1 is associated with oncologic outcome of advanced upper urinary tract urothelial carcinoma. Int. J. Mol. Sci.20(7), 1653 (2019).
  • Zhao SJ , JiangYQ , XuNWet al. SPARCL1 suppresses osteosarcoma metastasis and recruits macrophages by activation of canonical WNT/beta-catenin signaling through stabilization of the WNT-receptor complex. Oncogene37(8), 1049–1061 (2018).
  • Hu H , ZhangH , GeWet al. Secreted protein acidic and rich in cysteines-like 1 suppresses aggressiveness and predicts better survival in colorectal cancers. Clin. Cancer. Res.18(19), 5438–5448 (2012).
  • Cerami E , GaoJ , DogrusozUet al. The cBio cancer genomics portal, an open platform for exploring multidimensional cancer genomics data. Cancer Discov.2(5), 401–404 (2012).
  • Hu H . Study of novel tumor metastasis-related gene SPARCL1 [PhD dissertation]. Zhejiang University, Hangzhou, China (2010).
  • Nakamura Y , HokutoD , KoyamaFet al. The prognosis and recurrence pattern of right- and left-sided colon cancer in Stage II, Stage III, and liver metastasis after curative resection. Ann. Coloproctol. doi:10.3393/ac.2020.09.14 (2020) ( Epub ahead of print).
  • Shida D , InoueM , TanabeTet al. Prognostic impact of primary tumor location in Stage III colorectal cancer-right-sided colon versus left-sided colon versus rectum, a nationwide multicenter retrospective study. J. Gastroenterol.55(10), 958–968 (2020).
  • Hu H , CaiW , ZhengS , GeW. SPARCL1, a novel prognostic predictive factor for GI malignancies, a meta-analysis. Cell Physiol. Biochem.44(4), 1485–1496 (2017).
  • Ge W , HuH , CaiWet al. High-risk Stage III colon cancer patients identified by a novel five-gene mutational signature are characterized by upregulation of IL-23A and gut bacterial translocation of the tumor microenvironment. Int. J. Cancer146(7), 2027–2035 (2020).
  • Schubeler D . Function and information content of DNA methylation. Nature517(7534), 321–326 (2015).
  • Yin Y , MorgunovaE , JolmaAet al. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science356(6337), e2239 (2017).
  • Brenet F , MohM , FunkPet al. DNA methylation of the first exon is tightly linked to transcriptional silencing. PLoS ONE6(1), e14524 (2011).
  • Bormann F , Rodriguez-ParedesM , LasitschkaFet al. Cell-of-origin DNA methylation signatures are maintained during colorectal carcinogenesis. Cell Rep.23(11), 3407–3418 (2018).
  • Gallois C , Laurent-PuigP , TaiebJ. Methylator phenotype in colorectal cancer: a prognostic factor or not?Crit. Rev. Oncol. Hematol.99, 74–80 (2016).
  • Hurley PJ , HughesRM , SimonsBWet al. Androgen-regulated SPARCL1 in the tumor microenvironment inhibits metastatic progression. Cancer Res.75(20), 4322–4334 (2015).
  • Wu DM , ShiJ , LiuT , DengSH , HanR , XuY. Integrated analysis reveals down-regulation of SPARCL1 is correlated with cervical cancer development and progression. Cancer Biomark.21(2), 355–365 (2018).
  • Taieb J , KourieHR , EmileJFet al. Association of prognostic value of primary tumor location in stage III colon cancer with RAS and BRAF mutational status. JAMA Oncol.4(7), e173695 (2018).
  • Song K , ZhaoW , WangW , ZhangN , WangK , ChangZ. Individualized predictive signatures for 5-fluorouracil-based chemotherapy in right- and left-sided colon cancer. Cancer Sci.109(6), 1939–1948 (2018).
  • Nawa T , KatoJ , KawamotoHet al. Differences between right- and left-sided colon cancer in patient characteristics, cancer morphology and histology. J. Gastroenterol. Hepatol.23(3), 418–423 (2008).
  • Missiaglia E , JacobsB , D’ArioGet al. Distal and proximal colon cancers differ in terms of molecular, pathological, and clinical features. Ann. Oncol.25(10), 1995–2001 (2014).
  • Deng G , KakarS , TanakaHet al. Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics. Eur. J. Cancer44(9), 1290–1301 (2008).
  • Maus MK , HannaDL , StephensCLet al. Distinct gene expression profiles of proximal and distal colorectal cancer, implications for cytotoxic and targeted therapy. Pharmacogenom. J.15(4), 354–362 (2015).
  • Sanz-Garcia E , ArgilesG , ElezE , TaberneroJ. BRAF mutant colorectal cancer, prognosis, treatment, and new perspectives. Ann. Oncol.28(11), 2648–2657 (2017).
  • Cremolini C , AntoniottiC , LonardiSet al. Primary tumor sidedness and benefit from FOLFOXIRI plus bevacizumab as initial therapy for metastatic colorectal cancer. Retrospective analysis of the TRIBE trial by GONO. Ann. Oncol.29(7), 1528–1534 (2018).
  • Clara Tenkerian DR , VictoriaL , AnikaKet al. SPARCL1 is an angiocrine inhibitor of tumorigenesis in colorectal carcinoma. Proceedings of: AACR Annual Meeting 2019.Atlanta, GA, USA, 29 March–3 April 2019 ( Abstract 30).
  • Isler SG , LudwigCU , Chiquet-EhrismannR , SchenkS. Evidence for transcriptional repression of SPARC-like 1, a gene downregulated in human lung tumors. Int. J. Oncol.25(4), 1073–1079 (2004).
  • Yan H , GuanQ , HeJet al. Individualized analysis reveals CpG sites with methylation aberrations in almost all lung adenocarcinoma tissues. J. Transl. Med.15(1), 26 (2017).
  • Zhu H , WangG , QianJ. Transcription factors as readers and effectors of DNA methylation. Nat. Rev. Genet.17(9), 551–565 (2016).
  • Banskota S , DahalS , KwonE , KimDY , KimJA. β-Catenin gene promoter hypermethylation by reactive oxygen species correlates with the migratory and invasive potentials of colon cancer cells. Cell Oncol. (Dordr.)41(5), 569–580 (2018).
  • Chen C , WangB , SunJet al. DAC can restore expression of NALP1 to suppress tumor growth in colon cancer. Cell Death Dis.6(1), e1602 (2015).

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