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Research Article

Resveratrol Affects ccRCC Cell Senescence and Macrophage Polarization by Regulating the Stability of CCNB1 by RBM15

ORCID Icon, , , &
Pages 895-910 | Received 25 Apr 2023, Accepted 11 Oct 2023, Published online: 01 Nov 2023

References

  • Xi W , ChenX , SunJet al. Combined treatment with valproic acid and 5-Aza-2′-deoxycytidine synergistically inhibits human clear cell renal cell carcinoma growth and migration. Med. Sci. Monit.24, 1034–1043 (2018).
  • Rausch M , WeissA , ZoetemelkMet al. Optimized combination of HDACI and TKI efficiently inhibits metabolic activity in renal cell carcinoma and overcomes sunitinib resistance. Cancers (Basel).12(11), (2020).
  • Jiang N , NiuG , PanYHet al. CBX4 transcriptionally suppresses KLF6 via interaction with HDAC1 to exert oncogenic activities in clear cell renal cell carcinoma. EBioMedicine.53, 102692 (2020).
  • Chen J , RenJJ , CaiJ , WangX. Efficacy and safety of HDACIs in the treatment of metastatic or unresectable renal cell carcinoma with a clear cell phenotype: a systematic review and meta-analysis. Medicine (Baltimore).100(31), e26788 (2021).
  • He L , LiH , WuAet al. Functions of N6-methyladenosine and its role in cancer. Mol. Cancer18(1), 176 (2019).
  • Liu L , LiH , HuDet al. Insights into N6-methyladenosine and programmed cell death in cancer. Mol. Cancer21(1), 32 (2022).
  • Wang S , GaoS , ZengYet al. N6-methyladenosine reader YTHDF1 promotes ARHGEF2 translation and RhoA signaling in colorectal cancer. Gastroenterology162(4), 1183–1196 (2022).
  • Wang T , KongS , TaoM , JuS. The potential role of RNA N6-methyladenosine in cancer progression. Mol. Cancer.19(1), 88 (2020).
  • Ren B , KwahMX , LiuCet al. Resveratrol for cancer therapy: challenges and future perspectives. Cancer Lett.515, 63–72 (2021).
  • Carter LG , D’orazioJA , PearsonKJ. Resveratrol and cancer: focus on in vivo evidence. Endocr. Relat. Cancer.21(3), R209–225 (2014).
  • Zaffaroni N , BerettaGL. Resveratrol and Prostate Cancer: The Power of Phytochemicals. Curr Med Chem.28(24), 4845–4862 (2021).
  • Gu YR , KimJ , NaJC , HanWK. Mitochondrial metabolic reprogramming by SIRT3 regulation ameliorates drug resistance in renal cell carcinoma. PLOS ONE17(6), e0269432 (2022).
  • Galiniak S , AebisherD , Bartusik-AebisherD. Health benefits of resveratrol administration. Acta Biochim. Pol.66(1), 13–21 (2019).
  • Rauf A , ImranM , ButtMSet al. Resveratrol as an anti-cancer agent: a review. Crit. Rev. Food Sci. Nutr.58(9), 1428–1447 (2018).
  • Yue B , SongC , YangLet al. METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer. Mol. Cancer.18(1), 142 (2019).
  • Zeng X , ChenK , LiLet al. Epigenetic activation of RBM15 promotes clear cell renal cell carcinoma growth, metastasis and macrophage infiltration by regulating the m6A modification of CXCL11. Free Radic. Biol. Med.184, 135–147 (2022).
  • Bian Y , WangX , ZhengZet al. Resveratrol drives cancer cell senescence via enhancing p38MAPK and DLC1 expressions. Food Funct.13(6), 3283–3293 (2022).
  • Ma F , MaY , LiuKet al. Resveratrol induces DNA damage-mediated cancer cell senescence through the DLC1-DYRK1A-EGFR axis. Food Funct.14(3), 1484–1497 (2023).
  • Zhang H , ZhangX , LiXet al. Effect of CCNB1 silencing on cell cycle, senescence, and apoptosis through the p53 signaling pathway in pancreatic cancer. J. Cell Physiol.234(1), 619–631 (2018).
  • Yang D , GuoQ , LiangYet al. Wogonin induces cellular senescence in breast cancer via suppressing TXNRD2 expression. Arch Toxicol.94(10), 3433–3447 (2020).
  • Vicente R , Mausset-BonnefontAL , JorgensenCet al. Cellular senescence impact on immune cell fate and function. Aging Cell.15(3), 400–406 (2016).
  • Lu L , LiY , WenH , FengC. Overexpression of miR-15b promotes resistance to sunitinib in renal cell carcinoma. J. Cancer.10(15), 3389–3396 (2019).
  • Ansari MSZ , StagniV , IuzzolinoAet al. Pharmacological targeting of CBP/p300 drives a redox/autophagy axis leading to senescence-induced growth arrest in non-small cell lung cancer cells. Cancer Gene Ther. doi: 10.1038/s41417-022-00524-8 (2022).
  • Feng Y , WangX , XuLet al. The transcription factor ZBP-89 suppresses p16 expression through a histone modification mechanism to affect cell senescence. Febs J.276(15), 4197–4206 (2009).
  • Birch J , GilJ. Senescence and the SASP: many therapeutic avenues. Genes Dev.34(23–24), 1565–1576 (2020).
  • Cuollo L , AntonangeliF , SantoniA , SorianiA. The senescence-associated secretory phenotype (SASP) in the challenging future of cancer therapy and age-related diseases. Biology (Basel).9(12), (2020).
  • He S , SharplessNE. Senescence in health and disease. Cell169(6), 1000–1011 (2017).
  • Liu Y , YangS , WangKet al. Cellular senescence and cancer: Focusing on traditional Chinese medicine and natural products. Cell Prolif.53(10), e12894 (2020).
  • Mabrouk N , GhioneS , LaurensVet al. Senescence and Cancer: Role of Nitric Oxide (NO) in SASP. Cancers (Basel).12(5), (2020).
  • Takasugi M , YoshidaY , OhtaniN. Cellular senescence and the tumour microenvironment. Mol. Oncol.16(18), 3333–3351 (2022).
  • Wang B , KohliJ , DemariaM. Senescent cells in cancer therapy: friends or foes?Trends Cancer6(10), 838–857 (2020).
  • Sun H , WangH , WangXet al. Aurora-A/SOX8/FOXK1 signaling axis promotes chemoresistance via suppression of cell senescence and induction of glucose metabolism in ovarian cancer organoids and cells. Theranostics10(15), 6928–6945 (2020).
  • Wang Y , ChenY , GuanLet al. Carnitine palmitoyltransferase 1C regulates cancer cell senescence through mitochondria-associated metabolic reprograming. Cell Death Differ.25(4), 735–748 (2018).
  • Chen KY , ChenCC , ChangYC , ChangMC. Resveratrol induced premature senescence and inhibited epithelial-mesenchymal transition of cancer cells via induction of tumor suppressor Rad9. PLOS ONE14(7), e0219317 (2019).
  • Farhadnejad H , EmamatH , ZandH. The effect of resveratrol on cellular senescence in normal and cancer cells: focusing on cancer and age-related diseases. Nutr Cancer71(7), 1175–1180 (2019).
  • Li YR , LiS , LinCC. Effect of resveratrol and pterostilbene on aging and longevity. Biofactors.44(1), 69–82 (2018).
  • Pyo IS , YunS , YoonYEet al. Mechanisms of aging and the preventive effects of resveratrol on age-related diseases. Molecules25(20), (2020).
  • Chen EB , QinX , PengKet al. HnRNPR-CCNB1/CENPF axis contributes to gastric cancer proliferation and metastasis. Aging (Albany NY).11(18), 7473–7491 (2019).
  • Xia P , ZhangH , XuKet al. MYC-targeted WDR4 promotes proliferation, metastasis, and sorafenib resistance by inducing CCNB1 translation in hepatocellular carcinoma. Cell Death Dis.12(7), 691 (2021).
  • Zou Y , RuanS , JinLet al. CDK1, CCNB1, and CCNB2 are prognostic biomarkers and correlated with immune infiltration in hepatocellular carcinoma. Med. Sci. Monit.26, e925289 (2020).
  • Shen L , KangL , WangDet al. Legumain-deficient macrophages promote senescence of tumor cells by sustaining JAK1/STAT1 activation. Cancer Lett.472, 40–49 (2020).

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