Transcriptome Profiling and ceRNA Network of Small Extracellular Vesicles from Resting and Degranulated Mast Cells

References

• Derakhshan T , BoyceJA , DwyerDF. Defining mast cell differentiation and heterogeneity through single-cell transcriptomics analysis. J. Allergy Clin. Immunol.150(4), 739–747 (2022).
   PubMed Web of Science ®Google Scholar
• Elieh Ali Komi D , WohrlS , BieloryL. Mast cell biology at molecular level: a comprehensive review. Clin. Rev. Allergy Immunol.58(3), 342–365 (2020).
   PubMed Web of Science ®Google Scholar
• Jain R , TikooS , WeningerW. Mast cell granules: modulating adaptive immune response remotely. J. Allergy Clin. Immunol.143(5), 1731–1733 (2019).
   PubMed Web of Science ®Google Scholar
• West PW , Bulfone-PausS. Mast cell tissue heterogeneity and specificity of immune cell recruitment. Front. Immunol.13, 932090 (2022).
   PubMed Web of Science ®Google Scholar
• Groot Kormelink T , ArkesteijnGJ , VanDe Lest CHet al. Mast cell degranulation is accompanied by the release of a selective subset of extracellular vesicles that contain mast cell-specific proteases. J. Immunol.197(8), 3382–3392 (2016).
   PubMed Web of Science ®Google Scholar
• Lecce M , MolfettaR , MilitoNDet al. FcepsilonRI signaling in the modulation of allergic response: role of mast cell-derived exosomes. Int. J. Mol. Sci.21(15), 5464 (2020).
   PubMed Web of Science ®Google Scholar
• Keller S , SandersonMP , StoeckA , AltevogtP. Exosomes: from biogenesis and secretion to biological function. Immunol. Lett.107(2), 102–108 (2006).
   PubMed Web of Science ®Google Scholar
• Yang D , ZhangW , ZhangHet al. Progress, opportunity, and perspective on exosome isolation – efforts for efficient exosome-based theranostics. Theranostics10(8), 3684–3707 (2020).
   PubMed Web of Science ®Google Scholar
• Ekstrom K , ValadiH , SjostrandMet al. Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. J. Extracell. Vesicles1, doi: 10.3402/jev.v1i0.18389 (2012).
   PubMedGoogle Scholar
• Valadi H , EkstromK , BossiosAet al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol.9(6), 654–659 (2007).
   PubMed Web of Science ®Google Scholar
• Wang J , GuS , QinB. Eosinophil and mast cell-derived exosomes promote integrity of intestinal mucosa via the NEAT1/miR-211-5p/glial cell line-derived neurotrophic factor axis in duodenum. Environ. Toxicol. doi: 10.1002/tox.23895 (2023) ( Online ahead of print).
   Web of Science ®Google Scholar
• Li M , ZhaoJ , CaoMet al. Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells. Biol. Res.53(1), 12 (2020).
   PubMed Web of Science ®Google Scholar
• Hu L , SiL , DaiXet al. Exosomal miR-409-3p secreted from activated mast cells promotes microglial migration, activation and neuroinflammation by targeting Nr4a2 to activate the NF-κB pathway. J. Neuroinflammation18(1), 68 (2021).
   PubMed Web of Science ®Google Scholar
• Salmena L , PolisenoL , TayYet al. A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? Cell 146(3), 353–358 (2011).
   PubMed Web of Science ®Google Scholar
• Liang Y , HuangS , QiaoLet al. Characterization of protein, long noncoding RNA and microRNA signatures in extracellular vesicles derived from resting and degranulated mast cells. J. Extracell. Vesicles9(1), 1697583 (2020).
   PubMed Web of Science ®Google Scholar
• Thapaliya M , ChompunudNa Ayudhya C , AmponnawaratA , RoyS , AliH. Mast cell-specific MRGPRX2: a key modulator of neuro-immune interaction in allergic diseases. Curr. Allergy Asthma Rep.21(1), 3 (2021).
   PubMed Web of Science ®Google Scholar
• Zhang Y , ShiY , LinJ , LiX , YangB , ZhouJ. Immune cell infiltration analysis demonstrates excessive mast cell activation in psoriasis. Front. Immunol.12, 773280 (2021).
   PubMed Web of Science ®Google Scholar
• Zhang A , YangJ , MaC , LiF , LuoH. Development and validation of a robust ferroptosis-related prognostic signature in lung adenocarcinoma. Front. Cell Dev. Biol.9, 616271 (2021).
   PubMed Web of Science ®Google Scholar
• Merluzzi S , BettoE , CeccaroniAA , MagrisR , GiuntaM , MionF. Mast cells, basophils and B cell connection network. Mol. Immunol.63(1), 94–103 (2015).
   PubMed Web of Science ®Google Scholar
• Skokos D , LePanse S , VillaIet al. Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes. J. Immunol.166(2), 868–876 (2001).
   PubMed Web of Science ®Google Scholar
• Shefler I , SalamonP , MekoriYA. Extracellular vesicles as emerging players in intercellular communication: relevance in mast cell-mediated pathophysiology. Int. J. Mol. Sci.22(17), 9176 (2021).
   PubMed Web of Science ®Google Scholar
• Liang Y , QiaoL , PengXet al. The chemokine receptor CCR1 is identified in mast cell-derived exosomes. Am. J. Transl. Res.10(2), 352–367 (2018).
   PubMed Web of Science ®Google Scholar
• Aye CC , TodaM , MorohoshiK , OnoSJ. Identification of genes and proteins specifically regulated by costimulation of mast cell Fcepsilon receptor I and chemokine receptor 1. Exp. Mol. Pathol.92(3), 267–274 (2012).
   PubMed Web of Science ®Google Scholar
• Mukai K , TsaiM , SaitoH , GalliSJ. Mast cells as sources of cytokines, chemokines, and growth factors. Immunol. Rev.282(1), 121–150 (2018).
   PubMed Web of Science ®Google Scholar
• Kuo CH , CollinsAM , BoettnerDRet al. Role of CCL7 in type I hypersensitivity reactions in murine experimental allergic conjunctivitis. J. Immunol.198(2), 645–656 (2017).
   PubMed Web of Science ®Google Scholar
• Korosec P , TurnerPJ , SilarMet al. Basophils, high-affinity IgE receptors, and CCL2 in human anaphylaxis. J. Allergy Clin. Immunol.140(3), 750–758; e715 (2017).
   PubMed Web of Science ®Google Scholar
• Eissmann MF , DijkstraC , JarnickiAet al. IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization. Nat. Commun.10(1), 2735 (2019).
   PubMedGoogle Scholar
• Mcdonald MK , TianY , QureshiRAet al. Functional significance of macrophage-derived exosomes in inflammation and pain. Pain155(8), 1527–1539 (2014).
   PubMed Web of Science ®Google Scholar
• Lv LL , FengY , WenYet al. Exosomal CCL2 from tubular epithelial cells is critical for albumin-induced tubulointerstitial inflammation. J. Am. Soc. Nephrol.29(3), 919–935 (2018).
   PubMed Web of Science ®Google Scholar
• Zhang W , SunY , BaiLet al. RBMS1 regulates lung cancer ferroptosis through translational control of SLC7A11. J. Clin. Invest131(22), e152067 (2021).
   PubMed Web of Science ®Google Scholar
• Zhang J , ZhangG , ZhangWet al. Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer. Cell Death Differ.29(11), 2247–2261 (2022).
   PubMed Web of Science ®Google Scholar
• Yu J , NavickasA , AsgharianHet al. RBMS1 suppresses colon cancer metastasis through targeted stabilization of its mRNA regulon. Cancer Discov.10(9), 1410–1423 (2020).
   PubMed Web of Science ®Google Scholar
• Habib K , BishayeeK , KangJet al. RNA binding protein Rbms1 enables neuronal differentiation and radial migration during neocortical development by binding and stabilizing the RNA message for Efr3a. Mol. Cells45(8), 588–602 (2022).
   PubMed Web of Science ®Google Scholar
• Zhang L , ZouL , SunP. Relationship between miR-378c and YY1 expression in patients with gastric cancer and the clinicopathological features. Cell Mol. Biol. Lett.26(1), 12 (2021).
   PubMed Web of Science ®Google Scholar
• Xia H , ZhangZ , YuanJ , NiuQ. The lncRNA PVT1 promotes invasive growth of lung adenocarcinoma cells by targeting miR-378c to regulate SLC2A1 expression. Hum. Cell34(1), 201–210 (2021).
   PubMed Web of Science ®Google Scholar
• Yang J , CaoLL , WangXPet al. Neuronal extracellular vesicle derived miR-98 prevents salvageable neurons from microglial phagocytosis in acute ischemic stroke. Cell Death Dis.12(1), 23 (2021).
   PubMed Web of Science ®Google Scholar
• Xu L , XuQ , DaiSet al. lncRNA Xist regulates sevoflurane-induced social and emotional impairment by modulating miR-98-5p/EDEM1 signaling axis in neonatal mice. Mol. Ther. Nucleic Acids24, 939–950 (2021).
   PubMedGoogle Scholar
• Sun X , LiX , MaSet al. MicroRNA-98-5p ameliorates oxygen-glucose deprivation/reoxygenation (OGD/R)-induced neuronal injury by inhibiting Bach1 and promoting Nrf2/ARE signaling. Biochem. Biophys. Res. Commun.507(1–4), 114–121 (2018).
   PubMed Web of Science ®Google Scholar
• Zhu X , ZouY , WuTet al. ANP32E contributes to gastric cancer progression via NUF2 upregulation. Mol. Med. Rep.26(3), 275 (2022).
   PubMed Web of Science ®Google Scholar
• Xiong Z , YeL , ZhenyuHet al. ANP32E induces tumorigenesis of triple-negative breast cancer cells by upregulating E2F1. Mol. Oncol.12(6), 896–912 (2018).
   PubMed Web of Science ®Google Scholar
• Zhang J , LanZ , QiuGet al. Over-expression of ANP32E is associated with poor prognosis of pancreatic cancer and promotes cell proliferation and migration through regulating beta-catenin. BMC Cancer20(1), 1065 (2020).
   PubMed Web of Science ®Google Scholar
• Cao W , ZhouW , LiMet al. A novel signature based on CeRNA and immune status predicts prognostic risk and drug sensitivity in gastric cancer patients. Front Immunol.13, 951135 (2022).
   PubMedGoogle Scholar
• Guo G , GongK , BeckleyNet al. EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulation. Nat. Cell Biol.24(8), 1291–1305 (2022).
   PubMed Web of Science ®Google Scholar
• Kim J , KangH , SonBet al. NRBF2-mediated autophagy contributes to metabolite replenishment and radioresistance in glioblastoma. Exp. Mol. Med.54(11), 1872–1885 (2022).
   PubMed Web of Science ®Google Scholar
• Zhang S , WangY , DaiSD , WangEH. Down-regulation of NKD1 increases the invasive potential of non-small-cell lung cancer and correlates with a poor prognosis. BMC Cancer11, 186 (2011).
   PubMed Web of Science ®Google Scholar
• Chen X , XuP , ZhuJ , LiuF. Downregulation of NKD1 in human osteosarcoma and its clinical significance. Mol. Med. Rep.17(1), 1111–1117 (2018).
   PubMed Web of Science ®Google Scholar
• Dong H , ZhangX , WangYet al. Suppression of brain mast cells degranulation inhibits microglial activation and central nervous system inflammation. Mol. Neurobiol.54(2), 997–1007 (2017).
   PubMed Web of Science ®Google Scholar
• Theoharides TC , CholevasC , PolyzoidisK , PolitisA. Long-COVID syndrome-associated brain fog and chemofog: luteolin to the rescue. Biofactors47(2), 232–241 (2021).
   PubMed Web of Science ®Google Scholar
• Sandhu JK , KulkaM. Decoding mast cell-microglia communication in neurodegenerative diseases. Int. J. Mol. Sci.22(3), 1093 (2021).
   PubMed Web of Science ®Google Scholar
• Gaudenzio N , BassoL. Mast cell-neuron axis in allergy. Curr. Opin. Immunol.77, 102213 (2022).
   PubMed Web of Science ®Google Scholar
• Gupta K , HarvimaIT. Mast cell-neural interactions contribute to pain and itch. Immunol. Rev.282(1), 168–187 (2018).
   PubMed Web of Science ®Google Scholar
• Ben S , HuangX , ShiYet al. Change in cytokine profiles released by mast cells mediated by lung cancer-derived exosome activation may contribute to cancer-associated coagulation disorders. Cell Commun. Signal.21(1), 97 (2023).
   PubMed Web of Science ®Google Scholar