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Research Highlights:Highlights from the latest articles in epigenomics

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Pages 505-507 | Published online: 05 Aug 2010

References

  • Archin NM , KeedyKS, EspesethAet al.: Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors.Aids23 , 1799–1806 (2009).
  • du Chene I , BasyukE, LinYLet al.: Suv39H1 and HP1γ are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency.EMBO J.26 , 424–435 (2007).
  • Blazkova J , TrejbalovaK, Gondois-ReyFet al.: CpG methylation controls reactivation of HIV from latency.PLoS Pathog.5 , E1000554 (2009).
  • Keedy KS , MargolisDM: Therapy for persistent HIV.Trends Pharmacol. Sci.31 , 206–211 (2010).
  • Yang HC , ShenL, SilicianoRF, PomerantzJL: Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation.Proc. Natl Acad. Sci. USA106 , 6321–6326 (2009).
  • Treand C , du Chene I, Bres V et al.: Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter. EMBO J.25 , 1690–1699 (2006).
  • Choi BS , LeeHS, OhYTet al.: Novel histone deacetylase inhibitors CG05 and CG06 effectively reactivate latently infected HIV-1.Aids24 , 609–611 (2010).
  • Matalon S , PalmerBE, NoldMF, FurlanA, KassuA, et al.: The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro. J. Acquir. Immune Defic. Syndr.54 , 1–9 (2010).
  • Shehu-Xhilaga M , RhodesD, WightmanFet al.: The novel histone deacetylase inhibitors metacept-1 and metacept-3 potently increase HIV-1 transcription in latently infected cells.Aids23 , 2047–2050 (2009).

References

  • Yang HC , ShenL, SilicianoRF, PomerantzJL: Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation.Proc. Natl Acad. Sci. USA106 , 6321–6326 (2009).
  • Archin NM , KeedyKS, EspesethAet al.: Expression of latent human immunodeficiency Type 1 is induced by novel and selective histone deacetylase inhibitors.Aids23 , 1799–1806 (2009).
  • du Chene I , BasyukE, LinYLet al.: Suv39H1 and HP1g are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency.EMBO J.26 , 424–435 (2007).
  • Blazkova J , TrejbalovaK, Gondois-ReyFet al.: CpG methylation controls reactivation of HIV from latency.PLoS Pathog.5 , E1000554 (2009).
  • Keedy KS , MargolisDM: Therapy for persistent HIV.Trends Pharmacol. Sci.31 , 206–211 (2010).
  • Treand C , du Chene I, Bres V et al.: Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter. EMBO J.25 , 1690–1699 (2006).
  • Imai K , TogamiH, OkamotoT: Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294.J. Biol. Chem.285 , 16538–16545 (2010).
  • Jenuwein T : The epigenetic magic of histone lysine methylation.FEBS J.273 , 3121–3135 (2006).
  • Epsztejn-Litman S , FeldmanN, Abu-RemailehMet al.: De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes.Nat. Struct. Mol. Biol.15 , 1176–1183 (2008).

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