References
- Malhotra D , SebatJ. CNVs: harbingers of a rare variant revolution in psychiatric genetics. Cell148(6) , 1223–1241 (2012).
- Rasetti R , WeinbergerDR. Intermediate phenotypes in psychiatric disorders. Curr. Opin. Genet. Dev.21(3) , 340–348 (2011).
- Ripke S , SandersAR, KendlerKS et al. Genome-wide association study identifies five new schizophrenia loci. Nat. Genet. 43(10) , 969–976 (2011).
- Sullivan PF . Puzzling over schizophrenia: schizophrenia as a pathway disease. Nat. Med.18(2) , 210–211 (2012).
- Zandi MS , IraniSR, LangB et al. Disease-relevant autoantibodies in first episode schizophrenia. J. Neurol. 258(4) , 686–688 (2011).
- Li T , LiZ, ChenP et al. Common variants in major histocompatibility complex region and TCF4 gene are significantly associated with schizophrenia in Han Chinese. Biol. Psychiatry 68(7) , 671–673 (2010).
- Bjornsson HT , SigurdssonMI, FallinMD et al. Intra-individual change over time in DNA methylation with familial clustering. JAMA 299(24) , 2877–2883 (2008).
- Wyatt RJ , TerminiBA, DavisJ. Part II. Sleep studies. Schizophr. Bull.1(4) , 45–66 (1971).
- Dolinoy DC , HuangD, JirtleRL. Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc. Natl Acad. Sci. USA104(32) , 13056–13061 (2007).
- Brown AS , SusserES. Prenatal nutritional deficiency and risk of adult schizophrenia. Schizophr. Bull.34(6) , 1054–1063 (2008).
- Roseboom TJ , PainterRC, Van Abeelen AF, Veenendaal MV, De Rooij SR. Hungry in the womb: what are the consequences? Lessons from the Dutch famine. Maturitas70(2) , 141–145 (2011).
- Weaver IC , CervoniN, ChampagneFA et al. Epigenetic programming by maternal behavior. Nat. Neurosci. 7(8) , 847–854 (2004).
- Mcgowan PO , SasakiA, D‘alessioAC et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat. Neurosci. 12(3) , 342–348 (2009).
- Schlinzig T , JohanssonS, GunnarA, EkströmTJ, NormanM. Epigenetic modulation at birth – altered DNA-methylation in white blood cells after Caesarean section. Acta Paediatr.98(7) , 1096–1099 (2009).
- Gavin DP , AkbarianS. Epigenetic and post-transcriptional dysregulation of gene expression in schizophrenia and related disease. Neurobiol. Dis.46(2) , 255–262 (2012).
- Guidotti A , AutaJ, ChenY et al. Epigenetic GABAergic targets in schizophrenia and bipolar disorder. Neuropharmacology 60(7–8) , 1007–1016 (2011).
- Roth TL , LubinFD, SodhiM, KleinmanJE. Epigenetic mechanisms in schizophrenia. Biochim. Biophys. Acta1790(9) , 869–877 (2009).
- Dempster EL , PidsleyR, SchalkwykLC et al. Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Hum. Mol. Genet. 20(24) , 4786–4796 (2011).
- Benes FM , BerrettaS. GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology25(1) , 1–27 (2001).
- Mill J , TangT, KaminskyZ et al. Epigenomic profiling reveals DNA-methylation changes associated with major psychosis. Am. J. Hum. Genet. 82(3) , 696–711 (2008).
- Melas PA , RogdakiM, OsbyU, SchallingM, LavebrattC, EkströmTJ. Epigenetic aberrations in leukocytes of patients with schizophrenia: association of global DNA methylation with antipsychotic drug treatment and disease onset. FASEB J.26(6) , 2712–2718 (2012).
- Kyriakopoulos M , FrangouS. Pathophysiology of early onset schizophrenia. Int. Rev. Psychiatry19(4) , 315–324 (2007).
- Söderlund J , SchroderJ, NordinC et al. Activation of brain interleukin-1β in schizophrenia. Mol. Psychiatry 14(12) , 1069–1071 (2009).
- Khojasteh-Fard M , TabriziM, AmoliMM. Is DNA methylation responsible for immune system dysfunction in schizophrenia? Med. Hypotheses77(4) , 573–579 (2011).
- Herceg Z , Hernandez-VargasH. New concepts of old epigenetic phenomena and their implications for selecting specific cell populations for epigenomic research. Epigenomics3(4) , 383–386 (2011).