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Editorial

Early-life Disruption of Epigenetic Marks May Contribute to the Origins of Mental Illness

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Pages 355-357 | Published online: 24 Aug 2012

References

  • Volpe TA , KidnerC, HallIM, TengG, GrewalSI, MartienssenRA. Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science297(5588) , 1833–1837 (2002).
  • Saxonov S , BergP, BrutlagDL. A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters. Proc. Natl Acad. Sci. USA103(5) , 1412–1417 (2006).
  • Jenuwein T , AllisCD. Translating the histone code. Science293(5532) , 1074–1080 (2001).
  • Feinberg AP , VogelsteinB. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature301(5895) , 89–92 (1983).
  • Fraga MF , BallestarE, PazMF et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc. Natl Acad. Sci. USA 102(30) , 10604–10609 (2005).
  • Jaenisch R , BirdA. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet.33(Suppl.) , 245–254 (2003).
  • Alisch RS , BarwickBG, ChopraP et al. Age-associated DNA methylation in pediatric populations. Genome Res. 22(4) , 623–632 (2012).
  • Craddock N , JonesI. Genetics of bipolar disorder. J. Med. Genet.36(8) , 585–594 (1999).
  • Sullivan PF , PrescottCA, KendlerKS. The subtypes of major depression in a twin registry. J. Affect Disord.68(2–3) , 273–284 (2002).
  • Kringlen E . Twin studies in schizophrenia with special emphasis on concordance figures. Am. J. Med. Genet.97(1) , 4–11 (2000).
  • Levy F , HayDA, McStephenM, WoodC, WaldmanI. Attention-deficit hyperactivity disorder: a category or a continuum? Genetic analysis of a large-scale twin study. J. Am. Acad. Child Adolesc. Psychiatry36(6) , 737–744 (1997).
  • Weaver IC , CervoniN, ChampagneFA et al. Epigenetic programming by maternal behavior. Nat. Neurosci. 7(8) , 847–854 (2004).
  • McGowan PO , SasakiA, D‘AlessioAC et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat. Neurosci. 12(3) , 342–348 (2009).
  • Brown AS , PattersonPH. Maternal infection and schizophrenia: implications for prevention. Schizophr. Bull.37(2) , 284–290 (2011).
  • Grayson DR , JiaX, ChenY et al. Reelin promoter hypermethylation in schizophrenia. Proc. Natl Acad. Sci. USA 102(26) , 9341–9346 (2005).
  • Abdolmaleky HM , ChengKH, FaraoneSV et al. Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder. Hum. Mol. Genet. 15(21) , 3132–3145 (2006).
  • Dempster EL , PidsleyR, SchalkwykLC et al. Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Hum. Mol. Genet. 20(24) , 4786–4796 (2011).
  • Chen Y , SharmaRP, CostaRH, CostaE, GraysonDR. On the epigenetic regulation of the human reelin promoter. Nucleic Acids Res.30(13) , 2930–2939 (2002).
  • Tremolizzo L , CarboniG, RuzickaWB et al. An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability. Proc. Natl Acad. Sci. USA 99(26) , 17095–17100 (2002).
  • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (4th Edition Text Revision). American Psychiatric Association, DC, USA (2000).
  • Perlis RH . Translating biomarkers to clinical practice. Mol. Psychiatry16(11) , 1076–1087 (2011).
  • Mayeux R , SchupfN. Blood-based biomarkers for Alzheimer‘s disease: plasma Aβ40 and Aβ42, and genetic variants. Neurobiol. Aging32(Suppl. 1) , S10–S19 (2011).

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