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Research Highlights

Research Highlights: Highlights from the Latest Articles in Advances in the Understanding of Sperm Epigenetics

Pages 21-24 | Published online: 15 Feb 2013

References

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References

  • Trimmer EE . Methylenetetrahydrofolate reductase: biochemical characterization and medical significance. Curr. Pharm. Des. doi:10.2174/1381213231163966128 (2012) (Epub ahead of print).
  • Matthews RG . Methylenetetrahydrofolate reductase: a common human polymorphism and its biochemical implications. Chem. Rec.2(1) , 4–12 (2002).
  • Rubes J , RybarR, PrinosilovaP et al. Genetic polymorphisms influence the susceptibility of men to sperm DNA damage associated with exposure to air pollution. Mutat. Res. 683(1–2) , 9–15 (2010).
  • Wu W , ShenO, QinY et al. Idiopathic male infertility is strongly associated with aberrant promoter methylation of methylenetetrahydrofolate reductase (MTHFR). PLoS ONE 5(11) , e13884 (2010).
  • Carrell DT , WilcoxAL, LowyL et al. Elevated sperm chromosome aneuploidy and apoptosis in patients with unexplained recurrent pregnancy loss. Obstet. Gynecol. 101(6) , 1229–1235 (2003).
  • Wu X , ZhaoL, ZhuH, HeD, TangW, LuoY. Association between the MTHFR C677T polymorphism and recurrent pregnancy loss: a meta-analysis. Genet. Test. Mol. Biomarkers16(7) , 806–811 (2012).
  • Rotondo JC , BosiS, BazzanE et al. Methylenetetrahydrofolate reductase gene promoter hypermethylation in semen samples of infertile couples correlates with recurrent spontaneous abortion. Hum. Reprod. 27(12) , 3632–3638 (2012).

References

  • Morcos L , GeB, KokaV et al. Genome-wide assessment of imprinted expression in human cells. Genome Biol. 12(3) , R25 (2011).
  • Kobayashi H , HiuraH, JohnRM et al. DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm. Eur. J. Hum. Genet. 17(12) , 1582–1591 (2009).
  • Hammoud SS , NixDA, HammoudAO, GibsonM, CairnsBR, CarrellDT. Genome-wide analysis identifies changes in histone retention and epigenetic modifications at developmental and imprinted gene loci in the sperm of infertile men. Hum. Reprod.26(9) , 2558–2569 (2011).
  • Nanassy L , CarrellDT. Paternal effects on early embryogenesis. J. Exp. Clin. Assist. Reprod.5 , 2 (2008).
  • Ankolkar M , PatilA, WarkeH et al. Methylation analysis of idiopathic recurrent spontaneous miscarriage cases reveals aberrant imprinting at H19 ICR in normozoospermic individuals. Fertil. Steril. 98(5) , 1186–1192 (2012).

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