References
- Kendler KS , PrescottCA, MyersJ, NealeMC. The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Arch. Gen. Psychiatry60(9) , 929–937 (2003).
- Caspi A , SugdenK, MoffittTE et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301(5631) , 386–389 (2003).
- Binder EB , BradleyRG, LiuW et al. Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA 299(11) , 1291–1305 (2008).
- Klengel T , MehtaD, AnackerC et al. Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat. Neurosci. 16(1) , 33–41 (2013).
- Xie P , KranzlerHR, PolingJ et al. Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder 3. Neuropsychopharmacology 35(8) , 1684–1692 (2010).
- Borghol N , SudermanM, McArdleW et al. Associations with early-life socio-economic position in adult DNA methylation. Int. J. Epidemiol. 41(1) , 62–74 (2012).
- McGowan PO , SasakiA, D‘AlessioAC et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat. Neurosci. 12(3) , 342–348 (2009).
- Szyf M . The early life environment and the epigenome. Biochim. Biophys. Acta1790(9) , 878–885 (2009).
- Weaver IC , CervoniN, ChampagneFA et al. Epigenetic programming by maternal behavior. Nat. Neurosci. 7(8) , 847–854 (2004).
- Lienert F , WirbelauerC, SomI, DeanA, MohnF, SchubelerD. Identification of genetic elements that autonomously determine DNA methylation states. Nat. Genet.43(11) , 1091–1097 (2011).
- Schalkwyk LC , MeaburnEL, SmithR et al. Allelic skewing of DNA methylation is widespread across the genome. Am. J. Hum. Genet. 86(2) , 196–212 (2010).
- Bell JT , PaiAA, PickrellJK et al. DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol. 12(1) , 13 (2011).
- Stadler MB , MurrR, BurgerL et al. DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature 480(7378) , 490–495 (2011).
- Kress C , ThomassinH, GrangeT. Active cytosine demethylation triggered by a nuclear receptor involves DNA strand breaks. Proc. Natl Acad. Sci. USA103(30) , 11112–11117 (2006).
- Thomassin H , FlavinM, EspinasML, GrangeT. Glucocorticoid-induced DNA demethylation and gene memory during development. EMBO J.20(8) , 1974–1983 (2001).
- Paakinaho V , MakkonenH, JaaskelainenT, PalvimoJJ. Glucocorticoid receptor activates poised FKBP51 locus through long-distance interactions. Mol. Endocrinol.24(3) , 511–525 (2010).
- Denissov S , van Driel M, Voit R et al. Identification of novel functional TBP-binding sites and general factor repertoires. EMBO J.26(4) , 944–954 (2007).
- Maurano MT , HumbertR, RynesE et al. Systematic localization of common disease-associated variation in regulatory DNA. Science 337(6099) , 1190–1195 (2012).
- Schadt EE , BjorkegrenJLM. NEW: network-enabled wisdom in biology, medicine, and health care. Sci. Transl. Med.4(115) , 8 (2012).
- Lee RS , TamashiroKL, YangX et al. Chronic corticosterone exposure increases expression and decreases deoxyribonucleic acid methylation of Fkbp5 in mice. Endocrinology 151(9) , 4332–4343 (2010).