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Research Highlights

Research Highlights: PRC2 Dysfunction through Multiple Mechanisms in Myeloid Malignancies

Pages 481-482 | Published online: 24 Sep 2013

References

References

  • Mak KS , FunnellAP, PearsonRC, CrossleyM. PU.1 and haematopoietic cell fate: dosage matters. Int. J. Cell Biol.2011 , 808524 (2011).
  • Shen X , LiuY, HsuYJ et al. EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Mol. Cell 32 , 491–502 (2008).
  • Lee TI , JennerRG, BoyerLA et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125 , 301–313 (2006).
  • Cheng JX , AnastasiJ, WatanabeK et al. Genome-wide profiling reveals epigenetic inactivation of the PU.1 pathway by histone H3 lysine 27 trimethylation in cytogenetically normal myelodysplastic syndrome. Leukemia 27(6) , 1291–1300 (2013).

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